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Tytuł:
Mechanistic insight into the free radical scavenging and xanthine oxidase (XO) inhibitor potent of monoacetylphloroglucinols (MAPGs).
Autorzy:
Prasetyo WE; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia.
Admojo BT; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia.
Kusumaningsih T; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia.
Marliyana SD; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia.
Wibowo FR; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia.
Firdaus M; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia.
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Źródło:
Free radical research [Free Radic Res] 2023 Dec; Vol. 57 (3), pp. 174-194. Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/chemistry
Xanthine Oxidase*/chemistry
Protons ; Molecular Docking Simulation ; Hydrogen ; Phenols ; Water ; Free Radicals ; Thermodynamics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Vitro Inhibition of Xanthine Oxidase Purified from Arthritis Serum Patients by Nanocurcumin and Artemisinin Active Compounds.
Autorzy:
Al-Dulaimy WYM; Department of Chemistry, College of Science, University of Diyala, Baquba 32001, Iraq.
Hussein AA; Department of Molecular and Medical Biotechnology, College of Biotechnology, Al-Nahrain University, Jadriya, Baghdad 64074, Iraq.
Mahdi MA; Department of Chemistry, College of Science, University of Diyala, Baquba 32001, Iraq.
Kadhom M; Department of Environmental Science, College of Energy and Environmental Science, Al-Karkh University of Science, Baghdad 10081, Iraq.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 29; Vol. 28 (13). Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
Xanthine Oxidase*/antagonists & inhibitors
Xanthine Oxidase*/blood
Curcumin*/chemistry
Curcumin*/pharmacology
Artemisinins*/chemistry
Artemisinins*/pharmacology
Arthritis*/blood
Arthritis*/enzymology
Humans ; Molecular Docking Simulation ; Allopurinol/chemistry ; Allopurinol/pharmacology ; Protein Binding
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
XDH and XO Research and Drug Discovery-Personal History.
Autorzy:
Nishino T; NESA LLC, Yamatomura Greenhouse 501, Honkomagome 6-13-6, Bunkyo-ku, Tokyo 113-0021, Japan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 30; Vol. 28 (11). Date of Electronic Publication: 2023 May 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Xanthine Oxidase*/metabolism
Xanthine Dehydrogenase*/metabolism
Animals ; Enzyme Inhibitors/pharmacology ; Drug Discovery ; Mammals/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining redox balance.
Autorzy:
Okesina, Kazeem Bidemi (AUTHOR)
Odetayo, Adeyemi Fatai (AUTHOR)
Adeyemi, Wale Johnson (AUTHOR)
Ajibare, Ayodeji Johnson (AUTHOR)
Okesina, Akeem Ayodeji (AUTHOR)
Olayaki, Luqman Aribidesi (AUTHOR)
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Źródło:
Laboratory Animal Research. 2/18/2024, Vol. 40 Issue 1, p1-10. 10p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Xanthine Oxidase-A Personal History.
Autorzy:
Hille R; Department of Biochemistry, University of California, Riverside, CA 92521, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 17; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Xanthine Oxidase*
Molybdenum*
Electron Spin Resonance Spectroscopy ; Xanthine Dehydrogenase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of Xanthine Oxidase Protects against Diabetic Kidney Disease through the Amelioration of Oxidative Stress via VEGF/VEGFR Axis and NOX-FoxO3a-eNOS Signaling Pathway.
Autorzy:
Yang KJ; Clinical Research Institute, Daejeon St. Mary's Hospital, 64, Daeheung-ro, Jung-gu, Daejeon 34943, Republic of Korea.
Choi WJ; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea.
Chang YK; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea.
Park CW; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea.
Kim SY; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea.
Hong YA; Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetic Nephropathies*/drug therapy
Diabetic Nephropathies*/enzymology
Xanthine Oxidase*/antagonists & inhibitors
Animals ; Humans ; Male ; Mice ; Endothelial Cells/metabolism ; Febuxostat/pharmacology ; Mice, Inbred C57BL ; NADPH Oxidases/metabolism ; Nitric Oxide Synthase Type III/metabolism ; Oxidative Stress ; RNA, Messenger/metabolism ; Signal Transduction ; Uric Acid/pharmacology ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Syntheses, Crystal Structures and Xanthine Oxidase Inhibitory Activity of Aroylhydrazones.
Autorzy:
Han YJ; Pingdingshan University. yongjun_.
Guo XY
Xue LW
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Źródło:
Acta chimica Slovenica [Acta Chim Slov] 2022 Dec 15; Vol. 69 (4), pp. 928-936. Date of Electronic Publication: 2022 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Hydrazones*/pharmacology
Hydrazones*/chemistry
Xanthine Oxidase*/antagonists & inhibitors
Xanthine Oxidase*/metabolism
Molecular Structure ; Proton Magnetic Resonance Spectroscopy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Insights into the Inhibitory Mechanism of Viniferifuran on Xanthine Oxidase by Multiple Spectroscopic Techniques and Molecular Docking.
Autorzy:
Yang Y; School of Basic Medicine, Guizhou Medical University, Guian New District, Guizhou 550025, China.; State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
Chen Q; State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
Ruan S; State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
Ao J; State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
Liao SG; School of Basic Medicine, Guizhou Medical University, Guian New District, Guizhou 550025, China.; State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 10; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 10.
Typ publikacji:
Journal Article
MeSH Terms:
Xanthine Oxidase*
Enzyme Inhibitors*/pharmacology
Enzyme Inhibitors*/chemistry
Molecular Docking Simulation ; Spectroscopy, Fourier Transform Infrared ; Kinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of Hydroxytyrosol Derivatives of Donepezil on the Activity of Enzymes Involved in Neurodegenerative Diseases and Oxidative Damage.
Autorzy:
D'Errico A; Department of Medical, Movement and Well-Being Sciences, University of Naples 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
Nasso R; Department of Medical, Movement and Well-Being Sciences, University of Naples 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
Rullo R; Institute for the Animal Production Systems in the Mediterranean Environment, Consiglio Nazionale delle Ricerche Piazzale Enrico Fermi 1, 80055 Portici, Italy.
Maiuolo J; Department of Health Science, Institute of Research for Food Safety & Health (IRC-FSH), University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.
Costanzo P; Department of Chemistry and Chemical Technologies, University of Calabria, Via P. Bucci, Cubo 12C, 87036 Rende, Italy.
Bonacci S; Department of Health Sciences, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.
Oliverio M; Department of Health Sciences, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.
De Vendittis E; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Napoli, Italy.
Masullo M; Department of Medical, Movement and Well-Being Sciences, University of Naples 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
Arcone R; Department of Medical, Movement and Well-Being Sciences, University of Naples 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 22; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/drug therapy
Phenylethyl Alcohol/*analogs & derivatives
Humans ; Donepezil/pharmacology ; Donepezil/therapeutic use ; Xanthine Oxidase ; Monoamine Oxidase Inhibitors/pharmacology ; Monoamine Oxidase Inhibitors/therapeutic use ; Monoamine Oxidase/metabolism ; Oxidative Stress ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chemical Comparison and Identification of Xanthine Oxidase Inhibitors of Dioscoreae Hypoglaucae Rhizoma and Dioscoreae Spongiosae Rhizoma by Chemometric Analysis and Spectrum-Effect Relationship.
Autorzy:
Rui G; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.; International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
Qin ZY; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.; International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
Chang YQ; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.; International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
Zheng YG; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.; Department of Pharmaceutical Engineering, Hebei Chemical & Pharmaceutical College, Shijiazhuang 050026, China.
Zhang D; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.; International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
Yao LM; Bethune International Peace Hospital, Shijiazhuang 050082, China.
Guo L; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.; International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 15; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Plants, Medicinal*
Drugs, Chinese Herbal*/chemistry
Saponins*/pharmacology
Xanthine Oxidase ; Chemometrics ; Molecular Docking Simulation ; Chromatography, High Pressure Liquid
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Zinc protects against lead-induced testicular damage via modulation of steroidogenic and xanthine oxidase/uric acid/caspase 3-mediated apoptotic signaling in male Wistar rats.
Autorzy:
Besong EE; Department of Physiology, Ebonyi State University, Abakaliki, Nigeria.
Ashonibare PJ; Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.; Reproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Osun State, Nigeria.
Obembe OO; Department of Physiology, College of Health Sciences, Osun State University, Osun State, Nigeria.
Folawiyo MA; Department of Physiology, College of Medicine, Ekiti State University, Ado-Ekiti, Nigeria.
Adeyemi DH; Department of Physiology, College of Health Sciences, Osun State University, Osun State, Nigeria.
Hamed MA; Reproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Osun State, Nigeria.; Department of Medical Laboratory Science, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria.; The Brainwill Laboratory, Osogbo, Osun State, Nigeria.
Akhigbe TM; Reproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Osun State, Nigeria.; Breeding and Plant Genetics Unit, Department of Agronomy, Osun State University, Osun State.
Akhigbe RE; Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.; Reproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Osun State, Nigeria.
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Źródło:
The aging male : the official journal of the International Society for the Study of the Aging Male [Aging Male] 2023 Dec; Vol. 26 (1), pp. 2224428.
Typ publikacji:
Journal Article
MeSH Terms:
Testis*/pathology
Uric Acid*
Rats ; Animals ; Male ; Rats, Wistar ; Xanthine Oxidase/metabolism ; Xanthine Oxidase/pharmacology ; Zinc/metabolism ; Zinc/pharmacology ; Caspase 3/metabolism ; Caspase 3/pharmacology ; Semen/metabolism ; Testosterone/metabolism ; Antioxidants/metabolism ; Oxidative Stress ; Apoptosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Discovery of coumaric acid derivatives hinted by coastal marine source to seek for uric acid lowering agents.
Autorzy:
Yang YS; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.; Research and Development Center, Nanjing Shibeitai Biotechnology Co., Ltd., Nanjing, China.
Wang B; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Liu J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Li Q; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Jiao QC; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Qin P; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.; Research and Development Center, Nanjing Shibeitai Biotechnology Co., Ltd., Nanjing, China.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2163241.
Typ publikacji:
Journal Article
MeSH Terms:
Allopurinol*/pharmacology
Allopurinol*/therapeutic use
Hyperuricemia*/drug therapy
Humans ; Mice ; Animals ; Uric Acid/therapeutic use ; Coumaric Acids ; Xanthine Oxidase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Improving the thermostability of Pseudoalteromonas Porphyrae κ-carrageenase by rational design and MD simulation.
Autorzy:
Sang, Yuyan (AUTHOR)
Huang, Xiaoyi (AUTHOR)
Li, Hebin (AUTHOR)
Hong, Tao (AUTHOR)
Zheng, Mingjing (AUTHOR)
Li, Zhipeng (AUTHOR)
Jiang, Zedong (AUTHOR)
Ni, Hui (AUTHOR)
Li, Qingbiao (AUTHOR)
Zhu, Yanbing (AUTHOR)
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Źródło:
AMB Express. 1/20/2024, Vol. 14 Issue 1, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Geranium tuberosum Metanol Ekstraktının Enzim İnhibitör Özellikleri ve Antimikrobiyal Aktivitesi.
Autorzy:
ALMAZ, Züleyha
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Alternatywny tytuł:
Enzyme Inhibitory Properties and Antimicrobial Activity of Geranium tuberosum Methanol Extract.
Źródło:
Journal of the Institute of Science & Technology / Fen Bilimleri Estitüsü Dergisi. Dec2023, Vol. 13 Issue 4, p2875-2882. 8p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Celebrating Versatility: Febuxostat's Multifaceted Therapeutic Application.
Autorzy:
Kraev, Krasimir Iliev (AUTHOR)
Geneva-Popova, Mariela Gencheva (AUTHOR)
Hristov, Bozhidar Krasimirov (AUTHOR)
Uchikov, Petar Angelov (AUTHOR)
Popova-Belova, Stanislava Dimitrova (AUTHOR)
Kraeva, Maria Ilieva (AUTHOR)
Basheva-Kraeva, Yordanka Mincheva (AUTHOR)
Stoyanova, Nina Staneva (AUTHOR)
Mitkova-Hristova, Vesela Todorova (AUTHOR)
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Źródło:
Life (2075-1729). Nov2023, Vol. 13 Issue 11, p2199. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthetic heterocyclic derivatives as promising xanthine oxidase inhibitors: An overview.
Autorzy:
Kaur G; University Institute of Pharma. Sciences, Chandigarh University, Mohali, India.
Singh A; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Arora G; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Monga A; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Jassal AK; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Uppal J; University Institute of Pharma. Sciences, Chandigarh University, Mohali, India.
Bedi PMS; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.; Drug and Pollution testing Laboratory, Guru Nanak Dev University, Amritsar, India.
Bora KS; University Institute of Pharma. Sciences, Chandigarh University, Mohali, India.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2022 Sep; Vol. 100 (3), pp. 443-468. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Gout*/drug therapy
Xanthine Oxidase*
Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of uric acid on ischemic diseases, stratified by lipid levels: a drug-target, nonlinear Mendelian randomization study.
Autorzy:
Kim J; Basgenbio Inc., Seoul, Republic of Korea.; Department of Statistics and Actuarial Science, College of Natural Sciences, Soongsil University, Seoul, Republic of Korea.
Lee SY; Basgenbio Inc., Seoul, Republic of Korea.
Lee J; Basgenbio Inc., Seoul, Republic of Korea.
Yoon S; Basgenbio Inc., Seoul, Republic of Korea.; Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea.
Kim EG; Basgenbio Inc., Seoul, Republic of Korea.
Lee E; Basgenbio Inc., Seoul, Republic of Korea.
Kim N; Basgenbio Inc., Seoul, Republic of Korea.; Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea.
Lee S; Basgenbio Inc., Seoul, Republic of Korea.
Gym H; Basgenbio Inc., Seoul, Republic of Korea.
Park SI; Department of Pharmacology, College of Medicine, Kangwon National University, 1 Gangwondaehak-gil, Chuncheon-si, Gangwon-do, 24341, Republic of Korea. .; Biomedical Research Institute, Kangwon National University Hospital, Chuncheon, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 16; Vol. 14 (1), pp. 1338. Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:
Journal Article
MeSH Terms:
Gout*/drug therapy
Gout*/genetics
Myocardial Infarction*
Humans ; Uric Acid ; Xanthine Oxidase/genetics ; Mendelian Randomization Analysis ; Cholesterol, LDL/genetics ; Cerebral Infarction/drug therapy ; Cerebral Infarction/genetics ; Triglycerides/genetics ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis, structural characterizations, in vitro biological evaluation and computational investigations of pyrazole derivatives as potential antidiabetic and antioxidant agents.
Autorzy:
Mortada S; Laboratory of Pharmacology and Toxicology, Biopharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Karrouchi K; Laboratory of Analytical Chemistry and Bromatology, Team of Formulation and Quality Control of Health Products, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco. .
Hamza EH; CERNE2D: Laboratory of Spectroscopy, Molecular Modelling, Materials, Nanomaterials, Water and Enviroment (LS3MN2E), Faculty of Sciences, Mohammed V University, Rabat, Morocco.
Oulmidi A; Institute of Condensed Matter and Nanosciences, Molecular Chemistry, Materials and Catalysis (IMCN/MOST), Université Catholique de Louvain, 1348, Louvain-la-Neuve, Belgium.
Bhat MA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
Mamad H; Central Laboratory of Hematology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Aalilou Y; Laboratory of Pharmacology and Toxicology, Biopharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Radi S; Laboratoire de Chimie Appliquée et Environnement (LCAE), Faculté des Sciences, Université Mohammed I, 60000, Oujda, Morocco.
Ansar M; Laboratory of Medicinal Chemistry, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Masrar A; Central Laboratory of Hematology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Faouzi MEA; Laboratory of Pharmacology and Toxicology, Biopharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 15; Vol. 14 (1), pp. 1312. Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoglycemic Agents*/chemistry
Diabetes Mellitus*
Humans ; Glycoside Hydrolase Inhibitors/pharmacology ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Molecular Docking Simulation ; alpha-Glucosidases/metabolism ; Xanthine Oxidase ; Spectroscopy, Fourier Transform Infrared ; Molecular Structure ; Pyrazoles/pharmacology ; alpha-Amylases/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 12113

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