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Wyszukujesz frazę ""Xanthones"" wg kryterium: Temat


Tytuł :
Destabilization of FoxM1 and Inhibition of Topoisomerase I Contribute to Cytotoxicity of Prenylated Xanthones Isolated from Metaxya rostrata.
Autorzy :
Mittermair E; Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.; Department of Pharmacognosy, University of Vienna, Vienna, Austria.
Schueffl H; Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.
Heffeter P; Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.
Krenn L; Department of Pharmacognosy, University of Vienna, Vienna, Austria.
Marian B; Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.
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Źródło :
Planta medica [Planta Med] 2020 Oct; Vol. 86 (15), pp. 1073-1079. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Topoisomerases, Type I*
Xanthones*/toxicity
Caco-2 Cells ; Cell Cycle Checkpoints ; Cell Line, Tumor ; Ferns/chemistry ; Forkhead Box Protein M1/genetics ; Humans
Czasopismo naukowe
Tytuł :
Antimicrobial activity of rhodomyrtone isolated from Rhodomyrtus tomentosa (Aiton) Hassk.
Autorzy :
Bach QN; Haiphong University of Medicine and Pharmacology, Haiphong, Vietnam.
Hongthong S; Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Department of Chemistry, Faculty of Science, Mahidol University, Bangkok, Thailand.
Quach LT; Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Pham LV; Haiphong University of Medicine and Pharmacology, Haiphong, Vietnam.
Pham TV; Haiphong University of Medicine and Pharmacology, Haiphong, Vietnam.
Kuhakarn C; Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Department of Chemistry, Faculty of Science, Mahidol University, Bangkok, Thailand.
Reutrakul V; Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Department of Chemistry, Faculty of Science, Mahidol University, Bangkok, Thailand.
Nguyen PTM; Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.; Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
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Źródło :
Natural product research [Nat Prod Res] 2020 Sep; Vol. 34 (17), pp. 2518-2523. Date of Electronic Publication: 2019 Jan 02.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*isolation & purification
Cariostatic Agents/*isolation & purification
Myrtaceae/*chemistry
Xanthones/*isolation & purification
Anti-Bacterial Agents/pharmacology ; Biofilms/drug effects ; Cariostatic Agents/pharmacology ; Humans ; Microbial Sensitivity Tests ; Molecular Structure ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Streptococcus mutans/drug effects ; Streptococcus mutans/enzymology ; Vietnam ; Xanthones/pharmacology
Czasopismo naukowe
Tytuł :
Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics.
Autorzy :
Hatami E; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA.
Jaggi M; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA; Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, USA; South Texas Center of Excellence in Cancer Research, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, USA.
Chauhan SC; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA; Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, USA; South Texas Center of Excellence in Cancer Research, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, USA.
Yallapu MM; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA; Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, USA; South Texas Center of Excellence in Cancer Research, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2020 Aug; Vol. 1874 (1), pp. 188381. Date of Electronic Publication: 2020 May 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antineoplastic Agents, Phytogenic/*administration & dosage
Nanomedicine/*methods
Neoplasms/*therapy
Radiation-Sensitizing Agents/*administration & dosage
Xanthones/*administration & dosage
Animals ; Antineoplastic Agents, Phytogenic/economics ; Chemoradiotherapy/economics ; Chemoradiotherapy/methods ; Clinical Trials, Phase II as Topic ; Dose-Response Relationship, Drug ; Drug Carriers/chemistry ; Drug Costs ; Garcinia/chemistry ; Humans ; Nanomedicine/economics ; Nanoparticles/chemistry ; Neoplasms/economics ; Radiation-Sensitizing Agents/economics ; Resins, Plant/chemistry ; Treatment Outcome ; Xanthones/economics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha.
Autorzy :
Yang J; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.
Fu W; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China. Electronic address: .
Xiang Q; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.
Tang Y; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.
Wu R; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.
Zheng C; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.
Lu Y; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.
Zhou H; Institute of Cardiovascular Disease of Integrated Traditional Chinese and Western Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China. Electronic address: .
Xu H; Institute of Cardiovascular Disease of Integrated Traditional Chinese and Western Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2020 Jun; Vol. 174, pp. 112329. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic*
Garcinia*
Xanthones*
Cell Line, Tumor ; Humans ; Molecular Structure
Czasopismo naukowe
Tytuł :
Two new xanthones, a new lignin, and twenty phenolic compounds from Smilax china and their NO production inhibitory activities.
Autorzy :
Zheng XW; Engineering Research Center of Modern Preparation Technology of TCM, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
Zhang L; Shanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
Zhang WY; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200000, China.
Zhang Y; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200000, China.
Wang JY; Shanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
Liu BC; Shanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
Hu XJ; Shanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
Hong YL; Shanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
Yang YQ; Yue Yang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
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Źródło :
Journal of Asian natural products research [J Asian Nat Prod Res] 2020 Jun; Vol. 22 (6), pp. 509-520. Date of Electronic Publication: 2019 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Smilax*
Xanthones*
China ; Lignin ; Molecular Structure
Czasopismo naukowe
Tytuł :
Xanthones from a lignicolous freshwater fungus (BCC 28210).
Autorzy :
Yoiprommarat S; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Kongthong S; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Choowong W; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Boonyuen N; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Isaka M; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Bunyapaiboonsri T; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
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Źródło :
Natural product research [Nat Prod Res] 2020 May; Vol. 34 (9), pp. 1233-1237. Date of Electronic Publication: 2019 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*isolation & purification
Antimalarials/*isolation & purification
Ascomycota/*chemistry
Xanthones/*isolation & purification
Anti-Bacterial Agents/chemistry ; Antimalarials/chemistry ; Ascomycota/metabolism ; Bacillus cereus/drug effects ; Fresh Water/microbiology ; Inhibitory Concentration 50 ; Microbial Sensitivity Tests ; Molecular Structure ; Naphthoquinones/isolation & purification ; Plant Extracts/isolation & purification ; Plasmodium falciparum/drug effects ; Xanthones/chemistry ; Xanthones/pharmacology
Czasopismo naukowe
Tytuł :
Design, synthesis and cholinesterase inhibitory activity of α -mangostin derivatives.
Autorzy :
Chi XQ; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Hou B; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Yang L; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.
Zi CT; College of Science, Yunnan Agricultural University, Kunming, People's Republic of China.
Lv YF; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Li JY; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Ren FC; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Yuan MY; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.
Hu JM; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.
Zhou J; State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People' s Republic of China.
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Źródło :
Natural product research [Nat Prod Res] 2020 May; Vol. 34 (10), pp. 1380-1388. Date of Electronic Publication: 2018 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
Cholinesterase Inhibitors/*chemistry
Garcinia mangostana/*chemistry
Xanthones/*chemical synthesis
Acetylcholinesterase/drug effects ; Butyrylcholinesterase/drug effects ; Cholinesterase Inhibitors/pharmacology ; Drug Design ; Fruit/chemistry ; Xanthones/chemistry ; Xanthones/pharmacology
Czasopismo naukowe
Tytuł :
Discovery and Optimization of α-Mangostin Derivatives as Novel PDE4 Inhibitors for the Treatment of Vascular Dementia.
Autorzy :
Liang J; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P. R. China.
Huang YY; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Zhou Q; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Gao Y; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Li Z; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Wu D; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Yu S; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P. R. China.
Guo L; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Chen Z; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts 02114, United States.
Huang L; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Liang SH; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts 02114, United States.
He X; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P. R. China.
Wu R; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
Luo HB; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Mar 26; Vol. 63 (6), pp. 3370-3380. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dementia, Vascular/*drug therapy
Phosphodiesterase 4 Inhibitors/*therapeutic use
Xanthones/*therapeutic use
Aminopyridines/metabolism ; Animals ; Benzamides/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 4/chemistry ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Cyclopropanes/metabolism ; Dogs ; Drug Design ; Humans ; Male ; Mice, Inbred C57BL ; Molecular Structure ; Phosphodiesterase 4 Inhibitors/chemical synthesis ; Phosphodiesterase 4 Inhibitors/metabolism ; Phosphodiesterase 4 Inhibitors/pharmacokinetics ; Protein Binding ; Rolipram/metabolism ; Rolipram/therapeutic use ; Structure-Activity Relationship ; Vomiting/prevention & control ; Xanthones/chemical synthesis ; Xanthones/metabolism ; Xanthones/pharmacokinetics
Czasopismo naukowe
Tytuł :
[Research on autophagy induced by two xanthone compounds in HepG2 cells].
Autorzy :
Wang YX; Shanxi Key Laboratory of Innovative Drug for the Treatment of Serious Diseases Basing on the Chronic Inflammation, Shanxi University of Traditional Chinese Medicine Jinzhong 030619, China.
Liu HY; Academy of Life Science, University of Science and Technology of China Hefei 230031, China.
Ren JH; Shanxi Key Laboratory of Innovative Drug for the Treatment of Serious Diseases Basing on the Chronic Inflammation, Shanxi University of Traditional Chinese Medicine Jinzhong 030619, China.
Zhang HF; Academy of Life Science, University of Science and Technology of China Hefei 230031, China.
Xue HQ; Shanxi Key Laboratory of Innovative Drug for the Treatment of Serious Diseases Basing on the Chronic Inflammation, Shanxi University of Traditional Chinese Medicine Jinzhong 030619, China.
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Źródło :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2020 May; Vol. 45 (9), pp. 2151-2157.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy*
Xanthones*
Apoptosis ; Cell Cycle ; Hep G2 Cells
Czasopismo naukowe
Tytuł :
Doxorubicin and α-Mangostin oppositely affect luminal breast cancer cell stemness evaluated by a new retinaldehyde-dependent ALDH assay in MCF-7 tumor spheroids.
Autorzy :
Bissoli I; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Muscari C; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Apr; Vol. 124, pp. 109927. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*drug therapy
Doxorubicin/*pharmacology
Neoplastic Stem Cells/*drug effects
Xanthones/*pharmacology
Aldehyde Dehydrogenase/metabolism ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Breast Neoplasms/pathology ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Doxorubicin/administration & dosage ; Female ; Humans ; Inhibitory Concentration 50 ; MCF-7 Cells ; Retinaldehyde/metabolism ; Spheroids, Cellular/drug effects ; Spheroids, Cellular/metabolism ; Xanthones/administration & dosage
Czasopismo naukowe
Tytuł :
α-Mangostin exhibits antidepressant-like effects mediated by the modification of GABAergic, serotonergic and dopaminergic systems.
Autorzy :
Fu T; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Liu X; Ningxia People's Hospital, Yinchuan, China.
Liu J; Jilin University, Changchun, China.
Cai E; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Zhao Y; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Li H; Jilin University, Changchun, China.
Zhang L; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Li P; Jilin University, Changchun, China.
Gao Y; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
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Źródło :
Natural product research [Nat Prod Res] 2020 Mar; Vol. 34 (6), pp. 868-871. Date of Electronic Publication: 2018 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antidepressive Agents/*isolation & purification
Dopamine/*metabolism
Serotonin/*metabolism
Xanthones/*pharmacology
gamma-Aminobutyric Acid/*metabolism
Animals ; Antidepressive Agents/chemistry ; Antidepressive Agents/pharmacology ; Brain/drug effects ; Brain/metabolism ; Depression/drug therapy ; Mice ; Xanthones/therapeutic use
Czasopismo naukowe
Tytuł :
Antibacterial Diphenyl Ether, Benzophenone and Xanthone Derivatives from Aspergillus flavipes.
Autorzy :
Ji YB; Research Center of Life and Environment Science, Harbin University of Commerce, Harbin, 150076, P. R. China.
Chen WJ; Research Center of Life and Environment Science, Harbin University of Commerce, Harbin, 150076, P. R. China.; Marine Science and Technology Institute, Yangzhou University, Yangzhou, 225127, P. R. China.
Shan TZ; Marine Science and Technology Institute, Yangzhou University, Yangzhou, 225127, P. R. China.
Sun BY; Marine Science and Technology Institute, Yangzhou University, Yangzhou, 225127, P. R. China.
Yan PC; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, P. R. China.
Jiang W; Marine Science and Technology Institute, Yangzhou University, Yangzhou, 225127, P. R. China.
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2020 Feb; Vol. 17 (2), pp. e1900640. Date of Electronic Publication: 2020 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*chemistry
Aspergillus/*chemistry
Benzophenones/*chemistry
Phenyl Ethers/*chemistry
Xanthones/*chemistry
Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/pharmacology ; Aspergillus/metabolism ; Benzophenones/isolation & purification ; Benzophenones/pharmacology ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Magnetic Resonance Spectroscopy ; Microbial Sensitivity Tests ; Molecular Conformation ; Phenyl Ethers/isolation & purification ; Phenyl Ethers/pharmacology ; Xanthones/isolation & purification ; Xanthones/pharmacology
Czasopismo naukowe
Tytuł :
Xanthones and Cancer: from Natural Sources to Mechanisms of Action.
Autorzy :
Klein-Júnior LC; Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajaí - UNIVALI, 88302-901, Itajaí, Brazil.
Campos A; Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajaí - UNIVALI, 88302-901, Itajaí, Brazil.
Niero R; Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajaí - UNIVALI, 88302-901, Itajaí, Brazil.
Corrêa R; Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajaí - UNIVALI, 88302-901, Itajaí, Brazil.
Vander Heyden Y; Department of Analytical Chemistry, Applied Chemometrics and Molecular Modelling, Center for Pharmaceutical Research (CePhaR), Vrije Universiteit Brussel - VUB, B-1090, Brussels, Belgium.
Filho VC; Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajaí - UNIVALI, 88302-901, Itajaí, Brazil.
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2020 Feb; Vol. 17 (2), pp. e1900499. Date of Electronic Publication: 2020 Jan 31.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Products/*chemistry
Xanthones/*chemistry
Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Biological Products/metabolism ; Biological Products/therapeutic use ; Cell Cycle Checkpoints/drug effects ; DNA Repair/drug effects ; Humans ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Plants/chemistry ; Plants/metabolism ; Xanthones/metabolism ; Xanthones/therapeutic use
Czasopismo naukowe
Tytuł :
A solvent-assisted active loading technology to prepare gambogic acid and all-trans retinoic acid co-encapsulated liposomes for synergistic anticancer therapy.
Autorzy :
Na K; Wuya College of Innovation, Shenyang Pharmaceutical University, Wenhua Road, Shenyang, 110016, China.
Liu K; Research Institute, Jiangsu Hengrui Medicine Co., Ltd., No. 7 Kunlunshan Road, Lianyungang City, Jiangsu Province, People's Republic of China.
Yu J; Wuya College of Innovation, Shenyang Pharmaceutical University, Wenhua Road, Shenyang, 110016, China.
Wang X; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road, Shenyang, 110016, China.
Li M; Wuya College of Innovation, Shenyang Pharmaceutical University, Wenhua Road, Shenyang, 110016, China.
Tian C; Wuya College of Innovation, Shenyang Pharmaceutical University, Wenhua Road, Shenyang, 110016, China.
He H; Wuya College of Innovation, Shenyang Pharmaceutical University, Wenhua Road, Shenyang, 110016, China.
He Y; Research Institute, Jiangsu Hengrui Medicine Co., Ltd., No. 7 Kunlunshan Road, Lianyungang City, Jiangsu Province, People's Republic of China.
Wang Y; Wuya College of Innovation, Shenyang Pharmaceutical University, Wenhua Road, Shenyang, 110016, China. .
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Źródło :
Drug delivery and translational research [Drug Deliv Transl Res] 2020 Feb; Vol. 10 (1), pp. 146-158.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Breast Neoplasms/*drug therapy
Tretinoin/*administration & dosage
Xanthones/*administration & dosage
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Capsules ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Combinations ; Drug Compounding ; Drug Liberation ; Female ; Liposomes ; Mice ; Particle Size ; Solvents ; Tretinoin/chemistry ; Tretinoin/pharmacology ; Xanthones/chemistry ; Xanthones/pharmacology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Bioactive compounds from Cudrania tricuspidata: A natural anticancer source.
Autorzy :
Li X; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Yao Z; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Jiang X; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Sun J; >Department of Food Science and Engineering, Faculty of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, PR China.
Ran G; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Yang X; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Zhao Y; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Yan Y; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Chen Z; Department of Respiratory Medicine, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan, PR China.
Tian L; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
Bai W; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection, Jinan University, Guangzhou, PR China.
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Źródło :
Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2020; Vol. 60 (3), pp. 494-514. Date of Electronic Publication: 2018 Dec 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*isolation & purification
Antineoplastic Agents/*pharmacology
Flavonoids/*pharmacology
Moraceae/*chemistry
Plant Extracts/*chemistry
Plant Extracts/*pharmacology
Xanthones/*pharmacology
Antineoplastic Agents/chemistry ; Flavonoids/isolation & purification ; Fruit/chemistry ; Humans ; Xanthones/isolation & purification
Czasopismo naukowe
Tytuł :
CD44 targeted redox-triggered self-assembly with magnetic enhanced EPR effects for effective amplification of gambogic acid to treat triple-negative breast cancer.
Autorzy :
Sang M; Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing 210009, China. .
Han L
Luo R
Qu W
Zheng F
Zhang K
Liu F
Xue J
Liu W
Feng F
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Źródło :
Biomaterials science [Biomater Sci] 2019 Dec 17; Vol. 8 (1), pp. 212-223.
Typ publikacji :
Journal Article
MeSH Terms :
Hyaluronan Receptors/*antagonists & inhibitors
Hyaluronic Acid/*chemistry
Triple Negative Breast Neoplasms/*drug therapy
Xanthones/*administration & dosage
Animals ; Biological Availability ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Carriers ; Female ; Humans ; MCF-7 Cells ; Magnetite Nanoparticles ; Mice ; Oxidation-Reduction ; Polyethylene Glycols ; RAW 264.7 Cells ; Tissue Distribution ; Triple Negative Breast Neoplasms/metabolism ; Xanthones/chemistry ; Xanthones/pharmacokinetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Synthesis of Novel Xanthone Analogues and Their Growth Inhibitory Activity Against Human Lung Cancer A549 Cells.
Autorzy :
Wu J; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, People's Republic of China.
Dai J; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.; Department of Pharmacology, School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Zhang Y; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.; Department of Pharmacology, School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Wang J; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.
Huang L; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.
Ding H; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.
Li T; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.; Department of Pharmacy, Punan Hospital, Shanghai 200125, People's Republic of China.
Zhang Y; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.; Biomedical Innovation R&D Center, School of Medicine, Shanghai University, Shanghai, 20444, People's Republic of China.
Mao J; Department of Pharmacy, Shanghai Pudong New Area People's Hospital, Shanghai 201299, People's Republic of China.
Yu S; College of Pharmacy, Naval Medical University, Shanghai 200433, People's Republic of China.
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Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2019 Dec 13; Vol. 13, pp. 4239-4246. Date of Electronic Publication: 2019 Dec 13 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Xanthones/*chemical synthesis
Xanthones/*pharmacology
A549 Cells ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Structure-Activity Relationship ; Xanthones/chemistry
Czasopismo naukowe
Tytuł :
Chiral resolution of a caged xanthone and evaluation across a broad spectrum of breast cancer subtypes.
Autorzy :
Chantarasriwong O; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0358, USA; Department of Chemistry, Faculty of Science, King Mongkut's University of Technology Thonburi, 126 Pracha Uthit Rd., Bang Mod, Thung Khru, Bangkok 10140, Thailand.
Dorwart TJ; Department of Biology, Arcadia University, Glenside, PA 19038, USA.
Morales TH; Department of Biology, Arcadia University, Glenside, PA 19038, USA.
Maggio SF; Department of Biology, Arcadia University, Glenside, PA 19038, USA.
Settle AL; Department of Biology, Arcadia University, Glenside, PA 19038, USA.
Milcarek AT; Department of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ 08028, USA.
Alpaugh ML; Department of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ 08028, USA. Electronic address: .
Theodoraki MA; Department of Biology, Arcadia University, Glenside, PA 19038, USA. Electronic address: .
Theodorakis EA; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0358, USA. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2019 Dec; Vol. 93, pp. 103303. Date of Electronic Publication: 2019 Sep 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*chemistry
Xanthones/*chemistry
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Crystallography, X-Ray ; Drug Screening Assays, Antitumor ; Female ; Humans ; Molecular Conformation ; Stereoisomerism ; Xanthones/chemical synthesis ; Xanthones/pharmacology
Czasopismo naukowe
Tytuł :
Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticus .
Autorzy :
Jenis J; Research Center for Medicinal Plants, Al-Farabi Kazakh National University , Almaty , Kazakhstan.
Baiseitova A; Division of Applied Life Science (BK21 plus), IALS, Gyeongsang National University , Jinju , Republic of Korea.
Yoon SH; Division of Applied Life Science (BK21 plus), PMBBRC, RINS, Gyeongsang National University , Jinju , Republic of Korea.
Park C; Division of Applied Life Science (BK21 plus), PMBBRC, RINS, Gyeongsang National University , Jinju , Republic of Korea.
Kim JY; Division of Applied Life Science (BK21 plus), IALS, Gyeongsang National University , Jinju , Republic of Korea.
Li ZP; Division of Applied Life Science (BK21 plus), IALS, Gyeongsang National University , Jinju , Republic of Korea.
Lee KW; Division of Applied Life Science (BK21 plus), PMBBRC, RINS, Gyeongsang National University , Jinju , Republic of Korea.
Park KH; Division of Applied Life Science (BK21 plus), IALS, Gyeongsang National University , Jinju , Republic of Korea.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2019 Dec; Vol. 34 (1), pp. 1623-1632.
Typ publikacji :
Journal Article
MeSH Terms :
Artocarpus/*chemistry
Glycoside Hydrolase Inhibitors/*pharmacology
Plant Bark/*chemistry
Xanthones/*pharmacology
alpha-Glucosidases/*metabolism
Dose-Response Relationship, Drug ; Fluorescence ; Glycoside Hydrolase Inhibitors/chemistry ; Glycoside Hydrolase Inhibitors/isolation & purification ; Molecular Structure ; Structure-Activity Relationship ; Xanthones/chemistry ; Xanthones/isolation & purification
Czasopismo naukowe
Tytuł :
Antitumor Activity of Thermosensitive Hydrogels Packaging Gambogic Acid Nanoparticles and Tumor-Penetrating Peptide iRGD Against Gastric Cancer.
Autorzy :
Zhang D; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.; Department of Oncology, Tongde Hospital of Zhejiang Province, Hangzhou, People's Republic of China.
Chu Y; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Qian H; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Qian L; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Shao J; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Xu Q; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Yu L; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Li R; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Zhang Q; Department of Oncology, Jiangning Hospital, Nanjing, People's Republic of China.
Wu F; Department of Oncology, Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, People's Republic of China.
Liu B; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
Liu Q; The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, People's Republic of China.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2020 Jan 31; Vol. 15, pp. 735-747. Date of Electronic Publication: 2020 Jan 31 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Temperature*
Antineoplastic Agents/*therapeutic use
Hydrogels/*chemistry
Nanoparticles/*chemistry
Oligopeptides/*pharmacology
Stomach Neoplasms/*drug therapy
Xanthones/*therapeutic use
Animals ; Antineoplastic Agents/pharmacology ; Bombyx ; Cell Line, Tumor ; Fibroins/chemistry ; Glycerol/chemistry ; Humans ; Hypromellose Derivatives/chemistry ; Male ; Mice, Inbred BALB C ; Mice, Nude ; Nanoparticles/ultrastructure ; Porosity ; Stomach Neoplasms/pathology ; Tissue Distribution ; Xanthones/pharmacology
Czasopismo naukowe

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