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Tytuł:
Effect of formulation and route of administration on the distribution of 17-hydroxyprogesterone caproate in rats.
Autorzy:
Shaik, Imam H. (AUTHOR)
Chaphekar, Nupur (AUTHOR)
Vasudevan, Vignesh (AUTHOR)
Alshabi, Ali (AUTHOR)
Bastian, Jaime R. (AUTHOR)
Zhao, Wenchen (AUTHOR)
Caritis, Steve (AUTHOR)
Venkataramanan, Raman (AUTHOR)
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Źródło:
Xenobiotica. Mar2023, Vol. 53 Issue 3, p193-200. 8p.
Czasopismo naukowe
Tytuł:
The chlorophenoxy herbicide MCPA: a mechanistic basis for the observed differences in toxicological profile in humans and rats versus dogs.
Autorzy:
Gledhill, Alex (AUTHOR)
Bowen, Rachael (AUTHOR)
Bartels, Michael (AUTHOR)
Bond, Andrew (AUTHOR)
Chung, Git (AUTHOR)
Brown, Colin (AUTHOR)
Pye, Keith (AUTHOR)
Vora, Tarang (AUTHOR)
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Źródło:
Xenobiotica. May2022, Vol. 52 Issue 5, p498-510. 13p.
Czasopismo naukowe
Tytuł:
Pharmacokinetics and mass balance of vericiguat in rats and dogs and distribution in rats.
Autorzy:
Janssen, Wiebke (AUTHOR)
Schwarz, Thomas (AUTHOR)
Bütehorn, Ulf (AUTHOR)
Steinke, Wolfram (AUTHOR)
Sandmann, Steffen (AUTHOR)
Lang, Dieter (AUTHOR)
Kern, Armin (AUTHOR)
Hucke, Frank (AUTHOR)
Gerisch, Michael (AUTHOR)
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Źródło:
Xenobiotica. May2022, Vol. 52 Issue 5, p453-462. 10p.
Czasopismo naukowe
Tytuł:
Elucidating the structure and cytochrome P450-mediated mechanism for novel metabolites of GDC-0575 in rats.
Autorzy:
Zhang, Chenghong (AUTHOR)
Cho, Sungjoon (AUTHOR)
Napolitano, José G. (AUTHOR)
Russell, David (AUTHOR)
Gu, Christine (AUTHOR)
Deese, Alan (AUTHOR)
Han, Chong (AUTHOR)
Chen, Yuan (AUTHOR)
Ma, Shuguang (AUTHOR)
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Źródło:
Xenobiotica. Mar2022, Vol. 52 Issue 3, p219-228. 10p.
Czasopismo naukowe
Tytuł:
Sex differences in the pharmacokinetics and tissue residues of Macleaya cordata extracts in rats.
Autorzy:
Shen, Li-Xia (AUTHOR)
Liu, Gao-Feng (AUTHOR)
Song, Ji-Shuang (AUTHOR)
Cao, Yu-Hang (AUTHOR)
Peng, Xiong (AUTHOR)
Wu, Rong-Rong (AUTHOR)
Cao, Yan (AUTHOR)
Chen, Xiao-Jun (AUTHOR)
Liu, Zhaoying (AUTHOR)
Sun, Zhi-Liang (AUTHOR)
Wu, Yong (AUTHOR)
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Źródło:
Xenobiotica. Jan2022, Vol. 52 Issue 1, p46-53. 8p.
Czasopismo naukowe
Tytuł:
Preclinical pharmacokinetics and metabolism of MAK683, a clinical stage selective oral embryonic ectoderm development (EED) inhibitor for cancer treatment.
Autorzy:
Zhang, Ji Yue (AUTHOR)
Zhang, Jiangwei (AUTHOR)
Kiffe, Michael (AUTHOR)
Walles, Markus (AUTHOR)
Jin, Yi (AUTHOR)
Blanz, Joachim (AUTHOR)
Dayer, Jerôme (AUTHOR)
Sanchez, Arevalo (AUTHOR)
Zhang, Chunye (AUTHOR)
Zhang, Lijun (AUTHOR)
Huang, Ying (AUTHOR)
Oyang, Counde (AUTHOR)
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Źródło:
Xenobiotica. Jan2022, Vol. 52 Issue 1, p65-78. 14p.
Czasopismo naukowe
Tytuł:
Absorption, distribution, metabolism, and excretion of [C]TPN729 after oral administration to rats.
Autorzy:
Cheng, Huan (AUTHOR)
Yu, Jinghua (AUTHOR)
Yang, Chen (AUTHOR)
Zhang, Ning (AUTHOR)
Fan, Zhen (AUTHOR)
Zhang, Xiaojuan (AUTHOR)
Wang, Junchen (AUTHOR)
Wang, Zhen (AUTHOR)
Zhong, Da-fang (AUTHOR)
He, Ji-Xiang (AUTHOR)
Yan, Shu (AUTHOR)
Diao, Xingxing (AUTHOR)
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Źródło:
Xenobiotica. Jan2022, Vol. 52 Issue 1, p79-90. 12p.
Czasopismo naukowe
Tytuł:
UDP-glucuronosyltransferase 1A4-mediated N2-glucuronidation is the major metabolic pathway of lamotrigine in chimeric NOG-TKm30 mice with humanised-livers.
Autorzy:
Uehara, Shotaro (AUTHOR)
Higuchi, Yuichiro (AUTHOR)
Yoneda, Nao (AUTHOR)
Yamazaki, Hiroshi (AUTHOR)
Suemizu, Hiroshi (AUTHOR)
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Źródło:
Xenobiotica. Oct2021, Vol. 51 Issue 10, p1146-1154. 9p.
Czasopismo naukowe
Tytuł:
Pharmacokinetics, metabolism and off-target effects in the rat of 8-[(1H- benzotriazol-1-yl)amino]octanoic acid, a selective inhibitor of human cytochrome P450 4Z1: β-oxidation as a potential augmenting pathway for inhibition.
Autorzy:
Kowalski, John P. (AUTHOR)
Pelletier, Robert D. (AUTHOR)
McDonald, Matthew G. (AUTHOR)
Kelly, Edward J. (AUTHOR)
Rettie, Allan E. (AUTHOR)
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Źródło:
Xenobiotica. Aug2021, Vol. 51 Issue 8, p901-915. 15p.
Czasopismo naukowe
Tytuł:
Pharmacokinetics, tissue distribution and excretion of five rhubarb anthraquinones in rats after oral administration of effective fraction of anthraquinones from rheum officinale.
Autorzy:
Zhao, Di (AUTHOR)
Feng, Su-Xiang (AUTHOR)
Zhang, Hao-Jie (AUTHOR)
Zhang, Na (AUTHOR)
Liu, Xue-Fang (AUTHOR)
Wan, Yan (AUTHOR)
Zhou, Yu-Xiao (AUTHOR)
Li, Jian-Sheng (AUTHOR)
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Źródło:
Xenobiotica. Aug2021, Vol. 51 Issue 8, p916-925. 10p.
Czasopismo naukowe
Tytuł:
Rutaecarpine enhances the anti-diabetic activity and hepatic distribution of metformin via up-regulation of Oct1 in diabetic rats.
Autorzy:
Song, Xian-Mei (AUTHOR)
Li, Bing-Jie (AUTHOR)
Zhang, Yan-Yan (AUTHOR)
Ge, Wen-Jing (AUTHOR)
Zhang, She-Feng (AUTHOR)
Cui, Wei-Feng (AUTHOR)
Li, Geng-Sheng (AUTHOR)
Liang, Rui-Feng (AUTHOR)
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Źródło:
Xenobiotica. Jul2021, Vol. 51 Issue 7, p818-830. 13p.
Czasopismo naukowe
Tytuł:
Absorption, metabolism and excretion of pictilisib, a potent pan-class I phosphatidylinositol-3-Kinase (PI3K) inhibitor, in rats, dogs, and humans.
Autorzy:
Yue, Qin (AUTHOR)
Khojasteh, S. Cyrus (AUTHOR)
Cho, Sungjoon (AUTHOR)
Ma, Shuguang (AUTHOR)
Mulder, Teresa (AUTHOR)
Chen, John (AUTHOR)
Pang, Jodie (AUTHOR)
Ding, Xiao (AUTHOR)
Deese, Alan (AUTHOR)
Pellet, Jackson D. (AUTHOR)
Siebers, Nicholas (AUTHOR)
Joas, Lori (AUTHOR)
Salphati, Laurent (AUTHOR)
Ware, Joseph A. (AUTHOR)
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Źródło:
Xenobiotica. Jul2021, Vol. 51 Issue 7, p796-810. 15p.
Czasopismo naukowe
Tytuł:
Phenolic benzotriazoles: a class comparison of toxicokinetics of ultraviolet-light absorbers in male rats.
Autorzy:
Waidyanatha, Suramya (AUTHOR)
Mutlu, Esra (AUTHOR)
Gibbs, Seth (AUTHOR)
Pierfelice, Jessica (AUTHOR)
Smith, Jeremy P. (AUTHOR)
Burback, Brian (AUTHOR)
Blystone, Chad T. (AUTHOR)
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Źródło:
Xenobiotica. Jul2021, Vol. 51 Issue 7, p831-841. 11p.
Czasopismo naukowe
Tytuł:
Hepatotoxicological potential of P-toluic acid in humanised-liver mice investigated using simplified physiologically based pharmacokinetic models.
Autorzy:
Miura, Tomonori (AUTHOR)
Kamiya, Yusuke (AUTHOR)
Uehara, Shotaro (AUTHOR)
Murayama, Norie (AUTHOR)
Shimizu, Makiko (AUTHOR)
Suemizu, Hiroshi (AUTHOR)
Yamazaki, Hiroshi (AUTHOR)
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Źródło:
Xenobiotica. Jun2021, Vol. 51 Issue 6, p636-642. 7p.
Czasopismo naukowe
Tytuł:
Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human.
Autorzy:
Sasabe, Hiroyuki (AUTHOR)
Koga, Toshihisa (AUTHOR)
Furukawa, Masayuki (AUTHOR)
Matsunaga, Masayuki (AUTHOR)
Kaneko, Yosuke (AUTHOR)
Koyama, Noriyuki (AUTHOR)
Hirao, Yukihiro (AUTHOR)
Akazawa, Hitomi (AUTHOR)
Kawabata, Mitsuhiko (AUTHOR)
Kashiyama, Eiji (AUTHOR)
Takeuchi, Kenji (AUTHOR)
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Źródło:
Xenobiotica. May2021, Vol. 51 Issue 5, p590-604. 15p.
Czasopismo naukowe
Tytuł:
Inhibitory effect of ketoconazole, quinidine and 1-aminobenzotriazole on pharmacokinetics of l-tetrahydropalmatine and its metabolite in rats.
Autorzy:
Xiao, Weibin (AUTHOR)
Deng, Zhirong (AUTHOR)
Lai, Chongfa (AUTHOR)
Lu, Haoyang (AUTHOR)
Huang, Mutu (AUTHOR)
Wen, Yuguan (AUTHOR)
Shi, Lei (AUTHOR)
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Źródło:
Xenobiotica. Apr2021, Vol. 51 Issue 4, p447-454. 8p.
Czasopismo naukowe
Tytuł:
Plasma and hepatic concentrations of acetaminophen and its primary conjugates after oral administrations determined in experimental animals and humans and extrapolated by pharmacokinetic modeling.
Autorzy:
Toda, Akiko (AUTHOR)
Shimizu, Makiko (AUTHOR)
Uehara, Shotaro (AUTHOR)
Sasaki, Tatsuro (AUTHOR)
Miura, Tomonori (AUTHOR)
Mogi, Masayuki (AUTHOR)
Utoh, Masahiro (AUTHOR)
Suemizu, Hiroshi (AUTHOR)
Yamazaki, Hiroshi (AUTHOR)
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Źródło:
Xenobiotica. Mar2021, Vol. 51 Issue 3, p316-323. 8p.
Czasopismo naukowe
Tytuł:
Pharmacokinetics, tissue distribution and excretion of a novel long-acting human insulin analogue – recombinant insulin LysArg in rats.
Autorzy:
Cui, Tao (AUTHOR)
Li, Yazhuo (AUTHOR)
Wei, Zihong (AUTHOR)
Zhang, Xingyan (AUTHOR)
Li, Wei (AUTHOR)
Zhou, Wei (AUTHOR)
Lu, Jiangjie (AUTHOR)
Li, Jing (AUTHOR)
Yi, Xiulin (AUTHOR)
Zeng, Yong (AUTHOR)
Liu, Changxiao (AUTHOR)
Yan, Fengying (AUTHOR)
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Źródło:
Xenobiotica. Mar2021, Vol. 51 Issue 3, p307-315. 9p.
Czasopismo naukowe
Tytuł:
Comparative HPLC-MS/MS-based pharmacokinetic studies of multiple diterpenoid alkaloids following the administration of Zhenwu Tang and Radix Aconiti Lateralis Praeparata extracts to rats.
Autorzy:
Liu, Yanhao (AUTHOR)
Sun, Hua (AUTHOR)
Li, Chao (AUTHOR)
Pu, Zhicheng (AUTHOR)
Wu, Zijing (AUTHOR)
Xu, Maodi (AUTHOR)
Li, Xianghong (AUTHOR)
Zhang, Yuanxiang (AUTHOR)
Li, Hongjin (AUTHOR)
Dong, Jian (AUTHOR)
Bi, Runlei (AUTHOR)
Xie, Haitang (AUTHOR)
Liang, Dahu (AUTHOR)
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Źródło:
Xenobiotica. Mar2021, Vol. 51 Issue 3, p345-354. 10p.
Czasopismo naukowe
Tytuł:
Metabolism and disposition in rats, dogs, and humans of erdafitinib, an orally administered potent pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor.
Autorzy:
Scheers, Ellen (AUTHOR)
Borgmans, Carine (AUTHOR)
Keung, Chi (AUTHOR)
Bohets, Hilde (AUTHOR)
Wynant, Inneke (AUTHOR)
Poggesi, Italo (AUTHOR)
Cuyckens, Filip (AUTHOR)
Leclercq, Laurent (AUTHOR)
Mamidi, Rao N. V. S. (AUTHOR)
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Źródło:
Xenobiotica. Feb2021, Vol. 51 Issue 2, p177-193. 17p.
Czasopismo naukowe
Tytuł:
Comparative toxicokinetics of bisphenol S and bisphenol AF in male rats and mice following repeated exposure via feed.
Autorzy:
Waidyanatha, Suramya (AUTHOR)
Black, Sherry R. (AUTHOR)
Croutch, Claire R. (AUTHOR)
Collins, Bradley J. (AUTHOR)
Silinski, Melanie A. R. (AUTHOR)
Kerns, Season (AUTHOR)
Sutherland, Vicki (AUTHOR)
Robinson, Veronica G. (AUTHOR)
Aillon, Kristin (AUTHOR)
Fernando, Reshan A. (AUTHOR)
Mutlu, Esra (AUTHOR)
Fennell, Timothy R. (AUTHOR)
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Źródło:
Xenobiotica. Feb2021, Vol. 51 Issue 2, p210-221. 12p.
Czasopismo naukowe
Tytuł:
Kinetics of metabolism of deltamethrin and cis- and trans-permethrin in vitro. Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosol.
Autorzy:
Price, Roger J. (AUTHOR)
Scott, Mary P. (AUTHOR)
Cantrill, Carina (AUTHOR)
Higgins, Larry G. (AUTHOR)
Moreau, Marjory (AUTHOR)
Yoon, Miyoung (AUTHOR)
Clewell, Harvey J. (AUTHOR)
Creek, Moire R. (AUTHOR)
Osimitz, Thomas G. (AUTHOR)
Houston, J. Brian (AUTHOR)
Lake, Brian G. (AUTHOR)
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Źródło:
Xenobiotica. Jan2021, Vol. 51 Issue 1, p40-50. 11p.
Czasopismo naukowe
Tytuł:
Plasma protein binding, metabolism, reaction phenotyping and toxicokinetic studies of fenarimol after oral and intravenous administration in rats.
Autorzy:
Karsauliya, Kajal (AUTHOR)
Sonker, Ashish Kumar (AUTHOR)
Bhateria, Manisha (AUTHOR)
Taneja, Isha (AUTHOR)
Srivastava, Anshuman (AUTHOR)
Sharma, Manu (AUTHOR)
Singh, Sheelendra Pratap (AUTHOR)
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Źródło:
Xenobiotica. Jan2021, Vol. 51 Issue 1, p72-81. 10p.
Czasopismo naukowe
Tytuł:
Comparative assessment for rat strain differences in metabolic profiles of 14 drugs in Wistar Han and Sprague Dawley hepatocytes.
Autorzy:
Wang, Wei (AUTHOR)
Teresa, Mulder (AUTHOR)
Cai, Jingwei (AUTHOR)
Zhang, Chenghong (AUTHOR)
Wong, Susan (AUTHOR)
Yan, Zhengyin (AUTHOR)
Khojasteh, S. Cyrus (AUTHOR)
Zhang, Donglu (AUTHOR)
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Źródło:
Xenobiotica. Jan2021, Vol. 51 Issue 1, p15-23. 9p.
Czasopismo naukowe
Tytuł:
Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes.
Autorzy:
Hedges, Laura (AUTHOR)
Brown, Susan (AUTHOR)
MacLeod, A. Kenneth (AUTHOR)
Moreau, Marjory (AUTHOR)
Yoon, Miyoung (AUTHOR)
Creek, Moire R. (AUTHOR)
Osimitz, Thomas G. (AUTHOR)
Lake, Brian G. (AUTHOR)
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Źródło:
Xenobiotica. Dec2020, Vol. 50 Issue 12, p1434-1442. 9p.
Czasopismo naukowe
Tytuł:
Effect of rutin on pharmacokinetic modulation of diclofenac in rats.
Autorzy:
Dogra, Ashish (AUTHOR)
Gour, Abhishek (AUTHOR)
Bhatt, Shipra (AUTHOR)
Sharma, Priyanka (AUTHOR)
Sharma, Anjna (AUTHOR)
Kotwal, Pankul (AUTHOR)
Wazir, Priya (AUTHOR)
Mishra, Prashant (AUTHOR)
Singh, Gurdarshan (AUTHOR)
Nandi, Utpal (AUTHOR)
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Źródło:
Xenobiotica. Nov2020, Vol. 50 Issue 11, p1332-1340. 9p.
Czasopismo naukowe
Tytuł:
Differential changes in the pharmacokinetics of doxorubicin in diethylnitrosamine-induced hepatocarcinoma model rats.
Autorzy:
Pan, Jie (AUTHOR)
Lu, Yuan (AUTHOR)
Zhang, Shuai (AUTHOR)
Li, Yueting (AUTHOR)
Sun, Jia (AUTHOR)
Liu, Hua Chunhua (AUTHOR)
Gong, Zipeng (AUTHOR)
Huang, Jing (AUTHOR)
Cao, Chuang (AUTHOR)
Wang, Yonglin (AUTHOR)
Li, Yongjun (AUTHOR)
Liu, Ting (AUTHOR)
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Źródło:
Xenobiotica. Oct2020, Vol. 50 Issue 10, p1251-1257. 7p.
Czasopismo naukowe
Tytuł:
Effects of multidose simvastatin co-administration on pharmacokinetic profile of apatinib in rats by UPLC-MS/MS.
Autorzy:
Gao, Jinglin (AUTHOR)
Ren, Huan (AUTHOR)
Feng, Zhangying (AUTHOR)
Chen, Shanshan (AUTHOR)
Liang, Yu (AUTHOR)
Liu, Wanqiu (AUTHOR)
Zhou, Qian (AUTHOR)
Wang, Mingxia (AUTHOR)
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Źródło:
Xenobiotica. Sep2020, Vol. 50 Issue 9, p1115-1120. 6p.
Czasopismo naukowe
Tytuł:
Metabolic disposition of H3B-8800, an orally available small-molecule splicing modulator, in rats, monkeys, and humans.
Autorzy:
Rioux, Nathalie (AUTHOR)
Smith, Sherri (AUTHOR)
Colombo, Federico (AUTHOR)
Kim, Amy (AUTHOR)
Lai, W. George (AUTHOR)
Nix, Darrell (AUTHOR)
Siu, Y. Amy (AUTHOR)
Schindler, Joanne (AUTHOR)
Smith, Peter G. (AUTHOR)
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Źródło:
Xenobiotica. Sep2020, Vol. 50 Issue 9, p1101-1114. 14p.
Czasopismo naukowe
Tytuł:
Absorption, distribution, metabolism and excretion of darolutamide (a novel non-steroidal androgen receptor antagonist) in rats.
Autorzy:
Taavitsainen, Päivi (AUTHOR)
Gieschen, Hille (AUTHOR)
Korjamo, Timo (AUTHOR)
Kähkönen, Marja (AUTHOR)
Malmström, Chira (AUTHOR)
Prien, Olaf (AUTHOR)
Niehues, Michael (AUTHOR)
Sandmann, Steffen (AUTHOR)
Janssen, Wiebke (AUTHOR)
Koskinen, Mikko (AUTHOR)
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Źródło:
Xenobiotica. Aug2020, Vol. 50 Issue 8, p967-979. 13p.
Czasopismo naukowe
Tytuł:
Comparative pharmacokinetics of quercitrin, astragalin, afzelin and taxifolin in plasma after oral administration of Polygonum orientale inflorescence in sham-operated and myocardial ischemia–reperfusion injury rats.
Autorzy:
Zheng, Lin (AUTHOR)
Li, Yueting (AUTHOR)
Zhou, Zuying (AUTHOR)
Xiang, Wenying (AUTHOR)
Gong, Zipeng (AUTHOR)
Chen, Siying (AUTHOR)
Wang, Yonglin (AUTHOR)
Wang, Aimin (AUTHOR)
Lan, Yanyu (AUTHOR)
Li, Yongjun (AUTHOR)
Huang, Yong (AUTHOR)
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Źródło:
Xenobiotica. Jul2020, Vol. 50 Issue 7, p822-830. 9p.
Czasopismo naukowe
Tytuł:
Effect of treatment period with LC478, a disubstituted adamantayl derivative, on P-glycoprotein inhibition: its application to increase docetaxel absorption in rats.
Autorzy:
Han, Seung Yon (AUTHOR)
Kim, Eun-Sun (AUTHOR)
You, Byoung Hoon (AUTHOR)
Chae, Hee-Sung (AUTHOR)
Lu, Qili (AUTHOR)
Chin, Young-Won (AUTHOR)
Ahn, Hee-Chul (AUTHOR)
Chung, Suk-Jae (AUTHOR)
Lee, Kyeong (AUTHOR)
Choi, Young Hee (AUTHOR)
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Źródło:
Xenobiotica. Jul2020, Vol. 50 Issue 7, p863-874. 12p.
Czasopismo naukowe
Tytuł:
Effect of Hibiscus sabdariffa and Zingiber officinale on the antihypertensive activity and pharmacokinetic of losartan in hypertensive rats.
Autorzy:
Ahad, Abdul (AUTHOR)
Raish, Mohammad (AUTHOR)
Bin Jardan, Yousef A. (AUTHOR)
Alam, Mohd Aftab (AUTHOR)
Al-Mohizea, Abdullah M. (AUTHOR)
Al-Jenoobi, Fahad I. (AUTHOR)
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Źródło:
Xenobiotica. Jul2020, Vol. 50 Issue 7, p847-857. 11p.
Czasopismo naukowe
Tytuł:
Comparative pharmacokinetics of verapamil and norverapamil in normal and ulcerative colitis rats after oral administration of low and high dose verapamil by UPLC-MS/MS.
Autorzy:
Yao, Hongping (AUTHOR)
Wang, Changhe (AUTHOR)
Lu, Wen (AUTHOR)
Li, Wen (AUTHOR)
Jing, Wanghui (AUTHOR)
Zhang, Jiye (AUTHOR)
Yang, Guangde (AUTHOR)
Zeng, Aiguo (AUTHOR)
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Źródło:
Xenobiotica. Jun2020, Vol. 50 Issue 6, p713-721. 9p.
Czasopismo naukowe
Tytuł:
Toxicokinetics of perfluorohexanoic acid (PFHxA), perfluorooctanoic acid (PFOA) and perfluorodecanoic acid (PFDA) in male and female Hsd:Sprague dawley SD rats following intravenous or gavage administration.
Autorzy:
Dzierlenga, Anika L. (AUTHOR)
Robinson, Veronica G. (AUTHOR)
Waidyanatha, Suramya (AUTHOR)
DeVito, Michael J. (AUTHOR)
Eifrid, Max A. (AUTHOR)
Gibbs, Seth T. (AUTHOR)
Granville, Courtney A. (AUTHOR)
Blystone, Chad R. (AUTHOR)
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Źródło:
Xenobiotica. Jun2020, Vol. 50 Issue 6, p722-732. 11p.
Czasopismo naukowe
Tytuł:
A mechanistic modelling approach for the determination of the mechanisms of inhibition by cyclosporine on the uptake and metabolism of atorvastatin in rat hepatocytes using a high throughput uptake method.
Autorzy:
Carter, Simon J. (AUTHOR)
Ferecskó, Alex S. (AUTHOR)
King, Lloyd (AUTHOR)
Ménochet, Karelle (AUTHOR)
Parton, Ted (AUTHOR)
Chappell, Michael J. (AUTHOR)
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Źródło:
Xenobiotica. Apr2020, Vol. 50 Issue 4, p415-426. 12p.
Czasopismo naukowe
Tytuł:
Disposition and metabolism of sulfolane in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans.
Autorzy:
Waidyanatha, Suramya (AUTHOR)
Black, Sherry R. (AUTHOR)
Blystone, Chad R. (AUTHOR)
Patel, Purvi R. (AUTHOR)
Watson, Scott L. (AUTHOR)
Snyder, Rodney W. (AUTHOR)
Fennell, Timothy R. (AUTHOR)
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Źródło:
Xenobiotica. Apr2020, Vol. 50 Issue 4, p442-453. 12p.
Czasopismo naukowe
Tytuł:
Dihydromyricetin affect the pharmacokinetics of triptolide in rats.
Autorzy:
Deng, Yang (AUTHOR)
Guo, Lin (AUTHOR)
Cai, Hualin (AUTHOR)
Chen, Lei (AUTHOR)
Tan, Shenglan (AUTHOR)
Zhang, Bikui (AUTHOR)
Fang, Pingfei (AUTHOR)
Xiang, Daxiong (AUTHOR)
Li, Huande (AUTHOR)
He, Guixia (AUTHOR)
Yan, Miao (AUTHOR)
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Źródło:
Xenobiotica. Mar2020, Vol. 50 Issue 3, p332-338. 7p.
Czasopismo naukowe
Tytuł:
Stereoselective pharmacokinetics and tissue distribution of levodropropizine after administration of pure levodropropizine and the rac-dropropizine to Sprague–Dawley rats.
Autorzy:
Gabani, Bhavesh Babulal (AUTHOR)
Todmal, Umesh (AUTHOR)
Saini, Neeraj Kumar (AUTHOR)
Balakrishna, Vinod A. (AUTHOR)
Sulochana, Suresh P. (AUTHOR)
Timmapuram, Ashok (AUTHOR)
Zainuddin, Mohd (AUTHOR)
Balaji, Narayanan (AUTHOR)
Shuvranshu, Praharaj (AUTHOR)
Srinivas, Nuggehally R. (AUTHOR)
Mullangi, Ramesh (AUTHOR)
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Źródło:
Xenobiotica. Feb2020, Vol. 50 Issue 2, p135-144. 10p.
Czasopismo naukowe
Tytuł:
Evaluation of separate role of intestine and liver in first pass metabolism of budesonide in rat.
Autorzy:
Raje, Amol A.
Pathade, Vishal V.
Mahajan, Vallabh
Joshi, Kaushal
Tambe, Ashwini
Jinugu, Ramana
Madgula, Vamsi L. M.
Gaur, Ashwani
Kandikere, Vishwottam
Mookhtiar, Kasim A.
Deshpande, Radni D.
Patil, Chandragouda R.
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Źródło:
Xenobiotica. Dec2018, Vol. 48 Issue 12, p1206-1214. 9p.
Czasopismo naukowe
Tytuł:
Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys.
Autorzy:
Yamada, Makiko (AUTHOR)
Takei, Makoto (AUTHOR)
Suzuki, Eiko (AUTHOR)
Takakusa, Hideo (AUTHOR)
Kotsuma, Masakatsu (AUTHOR)
Washio, Takuo (AUTHOR)
Murayama, Nobuyuki (AUTHOR)
Inoue, Shin-ichi (AUTHOR)
Izumi, Takashi (AUTHOR)
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Źródło:
Xenobiotica. Dec2017, Vol. 47 Issue 12, p1090-1103. 14p.
Czasopismo naukowe
Tytuł:
Pharmacokinetic properties of trifolirhizin, (–)-maackiain, (–)-sophoranone and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran after intravenous and oral administration of Sophora tonkinensis extract in rats.
Autorzy:
Jang, Soo Min (AUTHOR)
Bae, Soo Hyeon (AUTHOR)
Choi, Woong-Kee (AUTHOR)
Park, Jung Bae (AUTHOR)
Kim, Doyun (AUTHOR)
Min, Jee Sun (AUTHOR)
Yoo, Hunseung (AUTHOR)
Kang, Minseok (AUTHOR)
Ryu, Keun Ho (AUTHOR)
Bae, Soo Kyung (AUTHOR)
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Źródło:
Xenobiotica. Dec2015, Vol. 45 Issue 12, p1092-1104. 13p.
Czasopismo naukowe

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