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Wyszukujesz frazę ""Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] NLMUID: 1306665"" wg kryterium: JN


Tytuł :
Oral bioavailability and pharmacokinetics of esculetin following intravenous and oral administration in rats.
Autorzy :
Kwak JH; College of Pharmacy, Kyungsung University, 309, Suyeong-ro, Nam-gu, Busan, 48434, Republic of Korea.; Functional Food & Drug Convergence Research Center, Industry-Academic Cooperation Foundation, Kyungsung University, 309, Suyeong-ro, Nam-gu, Busan, 48434, Republic of Korea.
Kim Y; School of Food Biotechnology and Nutrition, Kyungsung University, 309, Suyeong-ro, Nam-gu, Busan, 48434, Republic of Korea.; Functional Food & Drug Convergence Research Center, Industry-Academic Cooperation Foundation, Kyungsung University, 309, Suyeong-ro, Nam-gu, Busan, 48434, Republic of Korea.
Staatz CE; School of Pharmacy, The University of Queensland, Pharmacy Australia Centre of Excellence, 20 Cornwall St, Woolloongabba, QLD 4102, Brisbane, Australia.
Baek IH; College of Pharmacy, Kyungsung University, 309, Suyeong-ro, Nam-gu, Busan, 48434, Republic of Korea.; Functional Food & Drug Convergence Research Center, Industry-Academic Cooperation Foundation, Kyungsung University, 309, Suyeong-ro, Nam-gu, Busan, 48434, Republic of Korea.; School of Pharmacy, The University of Queensland, Pharmacy Australia Centre of Excellence, 20 Cornwall St, Woolloongabba, QLD 4102, Brisbane, Australia.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May 05, pp. 1-24. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation system for cell-permeable CYP3A4 inhibitory activity using 1α,25-dihydroxy-vitamin D 3 -induced intestinal cell lines.
Autorzy :
Ueno T; Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare, 60, Nakaorui-machi, Takasaki, Gunma 370-0033, Japan.; Suntory MONOZUKURI Expert Limited, 8-1-1 Seikadai, Seika-cho, Soraku-gun, Kyoto 619-0284, Japan.
Takahashi S; Faculty of Pharmacy, Takasaki University of Health and Welfare, 60, Nakaorui-machi, Takasaki, Gunma 370-0033, Japan.
Nakamura T; Faculty of Pharmacy, Takasaki University of Health and Welfare, 60, Nakaorui-machi, Takasaki, Gunma 370-0033, Japan.
Tanaka Y; Suntory MONOZUKURI Expert Limited, 8-1-1 Seikadai, Seika-cho, Soraku-gun, Kyoto 619-0284, Japan.
Hori H; Suntory MONOZUKURI Expert Limited, 8-1-1 Seikadai, Seika-cho, Soraku-gun, Kyoto 619-0284, Japan.
Mizoi K; Faculty of Pharmacy, Takasaki University of Health and Welfare, 60, Nakaorui-machi, Takasaki, Gunma 370-0033, Japan.
Ogihara T; Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare, 60, Nakaorui-machi, Takasaki, Gunma 370-0033, Japan.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May 04, pp. 1-24. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction.
Autorzy :
Li H; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Wang YG; Institute of Radiation Medicine Academy of Military Medical Sciences, Beijing, China.
Ma ZC; Institute of Radiation Medicine Academy of Military Medical Sciences, Beijing, China.
Yun-Hang G; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Ling S; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Teng-Fei C; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Guang-Ping Z; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Gao Y; Institute of Radiation Medicine Academy of Military Medical Sciences, Beijing, China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May 03, pp. 1-12. Date of Electronic Publication: 2021 May 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Pharmacokinetics, distribution and efficacy of triptolide PLGA microspheres after intra-articular injection in a rat rheumatoid arthritis model.
Autorzy :
Wang L; Pharmacy College, Chongqing Engineering Research Center of Pharmaceutical Sciences, Chongqing Medical and Pharmaceutical College, Chongqing, China.
Che K; Department of Pharmacy, Chongqing General Hospital, University of Chinese Academy of Sciences, Chongqing, 400014, China.
Liu Y; Pharmacy College, Chongqing Engineering Research Center of Pharmaceutical Sciences, Chongqing Medical and Pharmaceutical College, Chongqing, China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May 01, pp. 1-29. Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Absorption, metabolism and excretion of pictilisib, a potent Pan-Class I phosphatidylinositol-3-Kinase (PI3K) inhibitor, in rats, dogs, and humans.
Autorzy :
Yue Q; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Khojasteh SC; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Cho S; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Ma S; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Mulder T; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Chen J; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Pang J; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Ding X; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Deese A; Small Molecule Pharmaceutic Sciences, Genentech Inc, South San Francisco, CA, 94080.
Pellet J; Small Molecule Pharmaceutic Sciences, Genentech Inc, South San Francisco, CA, 94080.
Siebers N; Covance Clinical Research Unit, 3402 Kinsman Boulevard, Madison, WI, 53704.
Joas L; Covance Clinical Research Unit, 3402 Kinsman Boulevard, Madison, WI, 53704.
Salphati L; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, 94080.
Ware J; Clinical Pharmacology, Genentech Inc, South San Francisco, CA, 94080.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May 01, pp. 1-45. Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human.
Autorzy :
Sasabe H; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Koga T; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Furukawa M; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Matsunaga M; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Kaneko Y; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Koyama N; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Hirao Y; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Akazawa H; Department of CNS research, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Kawabata M; Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd, Kainan, Wakayama, Japan.
Kashiyama E; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
Takeuchi K; Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Kawauchi-cho, Tokushima, Japan.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 590-604. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In vitro evaluations for pharmacokinetic drug-drug interactions of a novel serotonin-dopamine activity modulator, brexpiprazole.
Autorzy :
Sasabe H; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
Koga T; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
Furukawa M; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
Matsunaga M; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
Sasahara K; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
Hashizume K; ADME & Tox. Research Institute, Sekisui Medical Co., Ltd., Naka-gun, Japan.
Oozone Y; ADME & Tox. Research Institute, Sekisui Medical Co., Ltd., Naka-gun, Japan.
Amunom I; Sekisui XenoTech LLC, Kansas City, KS, USA.
Torii M; Kashima Laboratory, LSIM Safety Institute Corporation, Kamisu-shi, Japan.
Umehara K; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
Kashiyama E; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
Takeuchi K; Drug metabolism and Pharmacokinetics, Tokushima Research Institute, Otsuka Pharmaceutical Co Ltd., Tokushima, Japan.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 522-535. Date of Electronic Publication: 2021 Mar 11.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Preliminary in vitro approach to evaluate the drug-drug interaction potential of EST73502, a dual µ-opioid receptor partial agonist and σ1 receptor antagonist.
Autorzy :
Ayet E; WELAB, Parc Científic Barcelona, Baldiri Reixac 4-8, Barcelona 08028, Spain.
Yeste S; WELAB, Parc Científic Barcelona, Baldiri Reixac 4-8, Barcelona 08028, Spain.
Reinoso RF; WELAB, Parc Científic Barcelona, Baldiri Reixac 4-8, Barcelona 08028, Spain.
Pretel MJ; Early ADME, Drug Discovery and Preclinical Development, ESTEVE Pharmaceuticals S.A, Barcelona, Spain.
Balada A; Early ADME, Drug Discovery and Preclinical Development, ESTEVE Pharmaceuticals S.A, Barcelona, Spain.
Serafini MT; WELAB, Parc Científic Barcelona, Baldiri Reixac 4-8, Barcelona 08028, Spain.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 501-512. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A comprehensive profiling and identification of liquiritin metabolites in rats using ultra-high-performance liquid chromatography coupled with linear ion trap-orbitrap mass spectrometer.
Autorzy :
Jiang S; School of Pharmacy, BIN ZHOU Medical University, Yantai, China.; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Wang S; School of Pharmacy, BIN ZHOU Medical University, Yantai, China.
Dong P; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Shi L; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Li Q; Shandong Institute for Food and Drug Control, Jinan, China.
Wei X; Shandong Institute for Food and Drug Control, Jinan, China.
Gao P; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Zhang J; School of Pharmacy, BIN ZHOU Medical University, Yantai, China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 564-581. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Methyl-hydroxylation and subsequent oxidation to produce carboxylic acid is the major metabolic pathway of tolbutamide in chimeric TK-NOG mice transplanted with human hepatocytes.
Autorzy :
Uehara S; Central Institute for Experimental Animals, Kawasaki, Japan.
Yoneda N; Central Institute for Experimental Animals, Kawasaki, Japan.
Higuchi Y; Central Institute for Experimental Animals, Kawasaki, Japan.
Yamazaki H; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan.
Suemizu H; Central Institute for Experimental Animals, Kawasaki, Japan.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 582-589. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Activation of Nrf2 decreases bile acid concentrations in livers of female mice.
Autorzy :
Liu J; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, P.R.China.
Lickteig AJ; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Zhang Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, P.R.China.
Csanaky IL; Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy Hospital and Clinics, Kansas City, MO, USA.; Division of Gastroenterology, Children's Mercy Hospital and Clinics, Kansas City, MO, USA.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA.
Klaassen CD; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 605-615. Date of Electronic Publication: 2021 Jan 31.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Metabolism, excretion, and pharmacokinetics of [ C]mirogabalin, a novel α 2 δ ligand, in healthy volunteers following oral administration.
Autorzy :
Yamamura N; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Mendel-Harary J; Clinical Pharmacology, Daiichi Sankyo Pharma Development, Basking Ridge, NJ, USA.
Brown K; Clinical Pharmacology, Daiichi Sankyo Pharma Development, Basking Ridge, NJ, USA.
Uchiyama M; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Urasaki Y; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Takahashi M; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Warren V; Clinical Pharmacology, Daiichi Sankyo Pharma Development, Basking Ridge, NJ, USA.
Vashi V; Clinical Pharmacology, Daiichi Sankyo Pharma Development, Basking Ridge, NJ, USA.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 549-563. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In vitro metabolism assessment of thiacloprid in rainbow trout and rat by LC-UV and high resolution-mass spectrometry.
Autorzy :
Serrano J; Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, United States Environmental Protection Agency, Duluth, MN, USA.
Kolanczyk RC; Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, United States Environmental Protection Agency, Duluth, MN, USA.
Blackwell BR; Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, United States Environmental Protection Agency, Duluth, MN, USA.
Sheedy BR; Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, United States Environmental Protection Agency, Duluth, MN, USA.
Tapper MA; Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, United States Environmental Protection Agency, Duluth, MN, USA.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 536-548. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Effect of CYP2C9 genetic polymorphism and breviscapine on losartan pharmacokinetics in healthy subjects.
Autorzy :
Huang HX; Department of Pharmacology, College of Pharmacy, Dali University, Dali, China.
Wu H; Department of Pharmacology, College of Pharmacy, Dali University, Dali, China.
Zhao Y; Department of Pharmacology, College of Pharmacy, Dali University, Dali, China.
Zhou T; Department of Pharmacology, College of Pharmacy, Dali University, Dali, China.
Ai X; Department of Pharmacology, College of Pharmacy, Dali University, Dali, China.
Dong Y; Department of Cardiology, The First Affiliated Hospital, Dali University, Dali, China.
Zhang Y; Dali State Comprehensive Technical Inspection Center, Dali University, Dali, China.
Lai Y; Department of Pharmacology, College of Pharmacy, Dali University, Dali, China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 616-623. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The characterisation of the in vitro metabolism and transport of 6-hydroxykynurenic acid, an important constituent of Ginkgo biloba extracts.
Autorzy :
Talap J; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
Shen Z; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
Nie J; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
Pan J; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
Xu M; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
Zeng K; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
He K; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
Ou F; Zhejiang Conba Pharmaceutical Co., Ltd, Zhejiang Provincial Key Laboratory of TCM Pharmaceutical Technology, Hangzhou, PR China.
He H; Zhejiang Conba Pharmaceutical Co., Ltd, Zhejiang Provincial Key Laboratory of TCM Pharmaceutical Technology, Hangzhou, PR China.
Yao J; Zhejiang Conba Pharmaceutical Co., Ltd, Zhejiang Provincial Key Laboratory of TCM Pharmaceutical Technology, Hangzhou, PR China.
Wang R; Zhejiang Conba Pharmaceutical Co., Ltd, Zhejiang Provincial Key Laboratory of TCM Pharmaceutical Technology, Hangzhou, PR China.
Yu L; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
Zeng S; Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center of Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, PR China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 May; Vol. 51 (5), pp. 513-521. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Metal-metal interaction and metal toxicity: a comparison between mammalian and D. melanogaster .
Autorzy :
Yu X; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Tian X; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Wang Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Zhu C; School of Life Sciences, Tianjin University, Tianjin 300072, China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Apr 30, pp. 1-34. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Drug-drug interaction potential and clinical pharmacokinetics of enerisant, a novel potent and selective histamine H 3 receptor antagonist.
Autorzy :
Terasaka S; Drug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Hachiuma K; Drug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Mano Y; Development Headquarters, Taisho Pharmaceutical Co., Ltd., Tokyo, Japan.
Onishi K; Development Headquarters, Taisho Pharmaceutical Co., Ltd., Tokyo, Japan.
Kitajima I; Development Headquarters, Taisho Pharmaceutical Co., Ltd., Tokyo, Japan.
Nishino I; Development Headquarters, Taisho Pharmaceutical Co., Ltd., Tokyo, Japan.
Endo H; Drug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Apr 28, pp. 1-10. Date of Electronic Publication: 2021 Apr 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Polymorphisms in xenobiotic metabolism-related genes in patients with hepatocellular carcinoma: a case-control study.
Autorzy :
Ferreira GD; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.
Fernandes GMM; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.
Penteado C; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.
Cória VR; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.
Galbiatti-Dias ALDS; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.; São José do Rio Preto Regional Medical School Foundation - FUNFARME, São José do Rio Preto, Brazil.
Russo A; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.
Castanhole-Nunes MMU; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.; São José do Rio Preto Regional Medical School Foundation - FUNFARME, São José do Rio Preto, Brazil.
Silva RFD; Study Group of Liver Tumors - GETF, Surgery Department, São José do Rio Preto Medical School Fundation - FAMERP/FUNFARME, São José do Rio Preto, Brazil.; São José do Rio Preto Regional Medical School Foundation - FUNFARME, São José do Rio Preto, Brazil.
Silva RCMAD; Study Group of Liver Tumors - GETF, Surgery Department, São José do Rio Preto Medical School Fundation - FAMERP/FUNFARME, São José do Rio Preto, Brazil.; São José do Rio Preto Regional Medical School Foundation - FUNFARME, São José do Rio Preto, Brazil.
Pavarino ÉC; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.; São José do Rio Preto Regional Medical School Foundation - FUNFARME, São José do Rio Preto, Brazil.
Torreglosa Ruiz Cintra M; Department of Biological Sciences - DCB, Federal University of the Triângulo Mineiro - UFTM, Uberaba, Brazil.
Goloni-Bertollo EM; Molecular Biology Department, Genetics and Molecular Biology Research Unit - UPGEM, São José do Rio Preto Medical School - FAMERP, São Jose do Rio Preto, Brazil.; São José do Rio Preto Regional Medical School Foundation - FUNFARME, São José do Rio Preto, Brazil.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Apr 26, pp. 1-9. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Metabolic Activation of Aegeline Mediated by CYP2C19.
Autorzy :
Tian M; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
Zhou S; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
Li W; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
Li J; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
Yang L; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
Peng Y; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.
Zheng J; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China.; State Key Laboratory of Functions and Applications of Medicinal Plants, Key Laboratory of Pharmaceutics of Guizhou Province, Guizhou Medical University, Guiyang, Guizhou 550025, P. R. China.; Key Laboratory of Environmental Pollution, Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou 550025, P. R. China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Apr 23, pp. 1-38. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of the drug-drug interaction potential for trazpiroben (TAK-906), a D 2 /D 3 receptor antagonist for gastroparesis, towards cytochrome P450s and transporters.
Autorzy :
Nishihara M; Drug Metabolism and Pharmacokinetics, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan.
Ramsden D; Global Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co, Cambridge, MA, USA.
Balani SK; Global Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co, Cambridge, MA, USA.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Apr 21, pp. 1-12. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji :
Journal Article
Czasopismo naukowe

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