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Wyszukujesz frazę ""Xenograft Model Antitumor Assays"" wg kryterium: Temat


Tytuł :
Protocol for chronic hepatitis B virus infection mouse model development by patient-derived orthotopic xenografts.
Autorzy :
Nagornykh AM; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
Tyumentseva MA; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
Tyumentsev AI; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
Akimkin VG; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
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Źródło :
PloS one [PLoS One] 2022 Feb 23; Vol. 17 (2), pp. e0264266. Date of Electronic Publication: 2022 Feb 23 (Print Publication: 2022).
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Hepatitis C, Chronic/*pathology
Primary Cell Culture/*methods
Xenograft Model Antitumor Assays/*standards
Animals ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/virology ; Cells, Cultured ; Hepatitis C, Chronic/virology ; Humans ; Liver Neoplasms/pathology ; Liver Neoplasms/virology ; Mice ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML.
Autorzy :
Lin S; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Larrue C; Translational Research Centre in Onco-hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Scheidegger NK; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Seong BKA; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Dharia NV; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Kuljanin M; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Wechsler CS; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.
Kugener G; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Robichaud AL; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.
Conway AS; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.
Mashaka T; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Mouche S; Translational Research Centre in Onco-hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Adane B; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Ryan JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Mancias JD; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Younger ST; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Piccioni F; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Lee LH; Division of Oncology, Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Wunderlich M; Division of Experimental Hematology and Cancer Biology, Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Letai A; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Tamburini J; Translational Research Centre in Onco-hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts. .; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
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Źródło :
Cancer discovery [Cancer Discov] 2022 Feb; Vol. 12 (2), pp. 432-449. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
CRISPR-Cas Systems*
Precision Medicine*
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Animals ; Humans ; Leukemia, Myeloid, Acute/genetics
Czasopismo naukowe
Tytuł :
Phospho-Aspirin (MDC-22) inhibits pancreatic cancer growth in patient-derived tumor xenografts and KPC mice by targeting EGFR: Enhanced efficacy in combination with irinotecan.
Autorzy :
Rodriguez Lanzi C; Department of Nutrition, University of California, Davis, One Shields Ave, Davis, CA 95616, USA.
Wei R; Department of Tea Science, Zhejiang Agriculture and Forestry University, Hangzhou 311300, China; University of California, Davis Comprehensive Cancer Center, Sacramento, CA 95817, USA.
Luo D; Department of Nutrition, University of California, Davis, One Shields Ave, Davis, CA 95616, USA; Department of Thyroid Surgery, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
Mackenzie GG; Department of Nutrition, University of California, Davis, One Shields Ave, Davis, CA 95616, USA; Department of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, NY 11794-8175, USA; University of California, Davis Comprehensive Cancer Center, Sacramento, CA 95817, USA. Electronic address: .
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Źródło :
Neoplasia (New York, N.Y.) [Neoplasia] 2022 Feb; Vol. 24 (2), pp. 133-144. Date of Electronic Publication: 2021 Dec 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*pharmacology
Aspirin/*pharmacology
Animals ; Aspirin/analogs & derivatives ; Disease Models, Animal ; Drug Therapy, Combination ; ErbB Receptors/antagonists & inhibitors ; Humans ; Irinotecan/pharmacology ; Mice ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/pathology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Defucosylated Mouse-Dog Chimeric Anti-EGFR Antibody Exerts Antitumor Activities in Mouse Xenograft Models of Canine Tumors.
Autorzy :
Li G; Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Ohishi T; Institute of Microbial Chemistry (BIKAKEN), Numazu, Microbial Chemistry Research Foundation, 18-24 Miyamoto, Numazu-shi 410-0301, Japan.
Kaneko MK; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Takei J; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Mizuno T; Laboratory of Molecular Diagnostics and Therapeutics, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
Kawada M; Institute of Microbial Chemistry (BIKAKEN), Numazu, Microbial Chemistry Research Foundation, 18-24 Miyamoto, Numazu-shi 410-0301, Japan.
Saito M; Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Suzuki H; Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Kato Y; Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
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Źródło :
Cells [Cells] 2021 Dec 20; Vol. 10 (12). Date of Electronic Publication: 2021 Dec 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Xenograft Model Antitumor Assays*
Antibodies, Monoclonal/*pharmacology
Antineoplastic Agents/*pharmacology
ErbB Receptors/*antagonists & inhibitors
Fucose/*metabolism
Recombinant Proteins/*pharmacology
Animals ; Antibody-Dependent Cell Cytotoxicity ; Body Weight/drug effects ; CHO Cells ; Complement System Proteins/metabolism ; Cricetulus ; Dogs ; Epidermal Growth Factor/pharmacology ; ErbB Receptors/metabolism ; Mice ; Tumor Burden/drug effects
Czasopismo naukowe
Tytuł :
Osteosarcoma Patient-derived Orthotopic Xenograft (PDOX) Models Used to Identify Novel and Effective Therapeutics: A Review.
Autorzy :
Higuchi T; AntiCancer, Inc., San Diego, CA, U.S.A.; Department of Surgery, University of California, San Diego, CA, U.S.A.; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Igarashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Yamamoto N; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Hayashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Kimura H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Miwa S; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Bouvet M; Department of Surgery, University of California, San Diego, CA, U.S.A.
Tsuchiya H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan .
Hoffman RM; AntiCancer, Inc., San Diego, CA, U.S.A.; .; Department of Surgery, University of California, San Diego, CA, U.S.A.
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Źródło :
Anticancer research [Anticancer Res] 2021 Dec; Vol. 41 (12), pp. 5865-5871.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Discovery*
Drug Screening Assays, Antitumor*/methods
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*pharmacology
Bone Neoplasms/*pathology
Osteosarcoma/*pathology
Animals ; Antineoplastic Agents/therapeutic use ; Biomarkers, Tumor ; Bone Neoplasms/drug therapy ; Bone Neoplasms/etiology ; Disease Models, Animal ; Disease Susceptibility ; Drug Resistance, Neoplasm ; Humans ; Mice ; Molecular Targeted Therapy ; Osteosarcoma/drug therapy ; Osteosarcoma/etiology ; Precision Medicine/methods
Czasopismo naukowe
Tytuł :
The Anti-Tumoral Potential of Phosphonate Analog of Sulforaphane in Zebrafish Xenograft Model.
Autorzy :
Rudzinska-Radecka M; Foundation of Research and Science Development, Rydygiera 8, 01-793 Warsaw, Poland.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Janczewski Ł; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Gajda A; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Godlewska M; Department of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.
Chmielewska-Krzesinska M; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
Wasowicz K; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
Podlasz P; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
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Źródło :
Cells [Cells] 2021 Nov 18; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*pharmacology
Isothiocyanates/*pharmacology
Organophosphonates/*pharmacology
Sulfoxides/*pharmacology
Zebrafish/*physiology
Animals ; Cell Line, Tumor ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/metabolism ; Humans ; Isothiocyanates/chemical synthesis ; Isothiocyanates/chemistry ; Microwaves ; Organophosphonates/chemical synthesis ; Organophosphonates/chemistry ; Signal Transduction/drug effects ; Sulfoxides/chemical synthesis ; Sulfoxides/chemistry ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis.
Autorzy :
Ma D; Department of Biological Chemistry, University of California, Irvine, CA, USA.
Hernandez GA; Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
Lefebvre AEYT; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
Alshetaiwi H; Department of Biological Chemistry, University of California, Irvine, CA, USA.; Department of Pathology, University of Hail, Hail, Saudi Arabia.
Blake K; Center for Complex Biological Systems, University of California, Irvine, CA, USA.
Dave KR; Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
Rauf M; Department of Biological Chemistry, University of California, Irvine, CA, USA.
Williams JW; Department of Biological Chemistry, University of California, Irvine, CA, USA.
Davis RT; Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
Evans KT; Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
Longworth A; Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
Masoud MYG; Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
Lee R; Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
Edwards RA; Department of Pathology & Laboratory Medicine, University of California, Irvine, CA, USA.
Digman MA; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
Kessenbrock K; Department of Biological Chemistry, University of California, Irvine, CA, USA.
Lawson DA; Department of Physiology and Biophysics, University of California, Irvine, CA, USA. .
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Źródło :
Communications biology [Commun Biol] 2021 Nov 05; Vol. 4 (1), pp. 1268. Date of Electronic Publication: 2021 Nov 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Heterografts*
Neoplasm Metastasis*
Xenograft Model Antitumor Assays*
Breast Neoplasms/*pathology
Animals ; Disease Models, Animal ; Female ; Mice ; Neoplasms, Experimental ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer.
Autorzy :
Lafferty A; Department of Physiology and Medical Physics, Precision Cancer Medicine Group, Royal College of Surgeons in Ireland, Dublin, Ireland.
O'Farrell AC; Department of Physiology and Medical Physics, Precision Cancer Medicine Group, Royal College of Surgeons in Ireland, Dublin, Ireland.
Migliardi G; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Khemka N; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Lindner AU; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Sassi F; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Zanella ER; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Salvucci M; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Vanderheyden E; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium.
Modave E; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium.
Boeckx B; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium.
Halang L; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Betge J; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Junior Clinical Cooperation Unit Translational Gastrointestinal Oncology and Preclinical Models, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ebert MPA; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Dicker P; Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Argilés G; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain.
Tabernero J; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain.
Dienstmann R; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain.
Medico E; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Lambrechts D; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium.
Bertotti A; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Isella C; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Trusolino L; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Byrne AT; Department of Physiology and Medical Physics, Precision Cancer Medicine Group, Royal College of Surgeons in Ireland, Dublin, Ireland. .; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
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Źródło :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Nov 01; Vol. 27 (21), pp. 5979-5992. Date of Electronic Publication: 2021 Aug 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Xenograft Model Antitumor Assays*
Colorectal Neoplasms/*drug therapy
Phenylurea Compounds/*therapeutic use
Pyridines/*therapeutic use
Animals ; Biomarkers, Tumor ; Colorectal Neoplasms/classification ; Colorectal Neoplasms/genetics ; Disease Models, Animal ; Mice ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Comparative study on the mechanisms of anti-lung cancer activities of three sulfated galactofucans.
Autorzy :
Zhang W; Department of Endocrinology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China.
Wu W; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China. .
Bao Y; Zhejiang Provincial Key Lab of Geriatrics, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China. .
Yan X; Marine Science and Technical College, Zhejiang Ocean University, Zhoushan, 316022, China.
Zhang F; Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Linhardt RJ; Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.; Department of Biological Science, Departments of Chemistry and Chemical Biology and Biomedical Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Jin W; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China. .; Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Mao G; Zhejiang Provincial Key Lab of Geriatrics, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China. .
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Źródło :
Food & function [Food Funct] 2021 Nov 01; Vol. 12 (21), pp. 10644-10657. Date of Electronic Publication: 2021 Nov 01.
Typ publikacji :
Journal Article
MeSH Terms :
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*pharmacology
Fucose/*chemistry
Fucose/*pharmacology
Galactose/*chemistry
Galactose/*pharmacology
A549 Cells ; Animals ; Antineoplastic Agents/chemistry ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms ; Mice ; Neoplasm Metastasis ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Sargassum/chemistry
Czasopismo naukowe
Tytuł :
Anti-tumor effects of rivoceranib against canine melanoma and mammary gland tumour in vitro and in vivo mouse xenograft models.
Autorzy :
Li Q; Department of Veterinary Medicine, College of Agriculture, YanBian University, YanJi, JiLin, China.
Kim YS; Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.; KPC Corporation, Oporo, Opo-eup, Gwangju-si, Gyeonggi-do, Korea.
An JH; Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Kwon JA; HLB LifeScience Co., Ltd., Teheran-ro, Gangnam-gu, Seoul, Republic of Korea.
Han SH; HLB LifeScience Co., Ltd., Teheran-ro, Gangnam-gu, Seoul, Republic of Korea.
Song WJ; Department of Veterinary Internal Medicine and Research Institute of Veterinary Science, College of Veterinary Medicine, Jeju National University, Jeju, 63243, Republic of Korea. .
Youn HY; Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea. .
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Źródło :
BMC veterinary research [BMC Vet Res] 2021 Oct 26; Vol. 17 (1), pp. 338. Date of Electronic Publication: 2021 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*therapeutic use
Dog Diseases/*drug therapy
Mammary Neoplasms, Animal/*drug therapy
Melanoma/*veterinary
Pyridines/*therapeutic use
Animals ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Dogs ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Melanoma/drug therapy ; Mice ; Neovascularization, Pathologic/prevention & control ; Vascular Endothelial Growth Factor Receptor-2/genetics ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
Tytuł :
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis.
Autorzy :
Yao H; Department of Neurosurgery, the First Affiliated Hospital of Soochow University, No188, Shizi Street, Suzhou, 215007, Jiangsu, China.
Liu J; Department of Neurosurgery, the First Affiliated Hospital of Soochow University, No188, Shizi Street, Suzhou, 215007, Jiangsu, China.
Zhang C; Department of Neurosurgery, the First Affiliated Hospital of Soochow University, No188, Shizi Street, Suzhou, 215007, Jiangsu, China.
Shao Y; Department of Neurosurgery, the First Affiliated Hospital of Soochow University, No188, Shizi Street, Suzhou, 215007, Jiangsu, China.
Li X; Department of Neurosurgery, Dushu Lake Hospital Affiliated of Soochow University, Suzhou, 215124, Jiangsu, China.
Yu Z; Department of Neurosurgery, the First Affiliated Hospital of Soochow University, No188, Shizi Street, Suzhou, 215007, Jiangsu, China. .
Huang Y; Department of Neurosurgery, the First Affiliated Hospital of Soochow University, No188, Shizi Street, Suzhou, 215007, Jiangsu, China. .; Department of Neurosurgery, Dushu Lake Hospital Affiliated of Soochow University, Suzhou, 215124, Jiangsu, China. .
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Źródło :
Cell death & disease [Cell Death Dis] 2021 Oct 11; Vol. 12 (10), pp. 927. Date of Electronic Publication: 2021 Oct 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*/drug effects
Xenograft Model Antitumor Assays*
Glioma/*metabolism
Glioma/*pathology
Myosin Heavy Chains/*metabolism
Pyridines/*pharmacology
Thrombospondin 1/*metabolism
Animals ; Carcinogenesis/drug effects ; Carcinogenesis/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Glioma/genetics ; Humans ; Inhibitory Concentration 50 ; Mice, Nude ; Models, Biological ; Neoplasm Invasiveness ; Protein Binding/drug effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Thrombospondin 1/genetics ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
Tytuł :
Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening.
Autorzy :
Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.
Requena D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
Ramos-Espiritu L; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York.
Ng D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
Bhola PD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
de Jong YP; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
Wang R; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
Narayan NJC; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Shebl B; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
Levin S; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
Michailidis E; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
Kabbani M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
Vercauteren KOA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.; Laboratory of Liver Infectious Diseases, Ghent University, Ghent, Belgium.; Institute of Tropical Medicine, Antwerp, Belgium.
Hurley AM; Hospital Program Direction, The Rockefeller University, New York, New York.
Farber BA; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Department of Surgery, Division of Pediatric Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Hammond WJ; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York.
Saltsman JA 3rd; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, Mount Sinai Hospital, New York, New York.
Weinberg EM; Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Glickman JF; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York.
Lyons BA; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico.
Ellison J; Division of Transplantation, Rush University Medical Center, Chicago, Illinois.
Schadde E; Department of Surgery, Division of Transplantation and Division of Surgical Oncology, Rush University Medical Center, Chicago, Illinois.
Hertl M; Division of Transplantation, Rush University Medical Center, Chicago, Illinois.
Leiting JL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota.
Truty MJ; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota.
Smoot RL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota.
Tierney F; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York.
Kato T; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York.
Wendel HG; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York.
LaQuaglia MP; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Coffino P; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.
Torbenson MS; Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota.
Ortiz MV; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Simon SM; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York. .
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Źródło :
Cancer discovery [Cancer Discov] 2021 Oct; Vol. 11 (10), pp. 2544-2563. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Xenograft Model Antitumor Assays*
Carcinoma, Hepatocellular/*drug therapy
Liver Neoplasms/*drug therapy
Aniline Compounds/therapeutic use ; Animals ; Antineoplastic Agents/therapeutic use ; Benzofurans/therapeutic use ; Carcinoma, Hepatocellular/genetics ; Female ; Humans ; Liver Neoplasms/genetics ; Male ; Mice ; Naphthoquinones/therapeutic use ; Sulfonamides/therapeutic use
SCR Disease Name :
Fibrolamellar hepatocellular carcinoma
Czasopismo naukowe
Tytuł :
Breaking down walls in prostate cancer with the MURAL collection of patient-derived xenografts.
Autorzy :
Bevan CL; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 17; Vol. 12 (1), pp. 5504. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Xenograft Model Antitumor Assays*
Prostatic Neoplasms/*pathology
Drug Resistance, Neoplasm ; Humans ; Male ; Neoplasm Metastasis ; Prostatic Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Genomic analysis and preclinical xenograft model development identify potential therapeutic targets for MYOD1-mutant soft-tissue sarcoma of childhood.
Autorzy :
Ting MA; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Reuther J; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.
Chandramohan R; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Voicu H; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.
Gandhi I; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.
Liu M; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Cortes-Santiago N; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.
Foster JH; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Hicks J; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.
Nuchtern J; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Division of Pediatric Surgery, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Scollon S; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Plon SE; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; The Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.; The Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Chintagumpala M; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; The Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Rainusso N; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; The Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Roy A; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.; The Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Parsons DW; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; The Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.; The Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
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Źródło :
The Journal of pathology [J Pathol] 2021 Sep; Vol. 255 (1), pp. 52-61. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Xenograft Model Antitumor Assays*
MyoD Protein/*genetics
Rhabdomyosarcoma/*genetics
Soft Tissue Neoplasms/*genetics
Adolescent ; Animals ; Antineoplastic Agents/pharmacology ; Child ; Female ; Genomics ; Humans ; Imidazoles/pharmacology ; Male ; Mice ; Mutation ; Quinolines/pharmacology ; Rhabdomyosarcoma/pathology ; Soft Tissue Neoplasms/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Patient-Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY).
Autorzy :
Boughey JC; Department of Surgery, Mayo Clinic, Rochester, Minnesota. .
Suman VJ; Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Yu J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota.
Santo K; Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Sinnwell JP; Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Carter JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Kalari KR; Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Tang X; Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
McLaughlin SA; Department of Surgery, Mayo Clinic, Jacksonville, Florida.
Moreno-Aspitia A; Department of Medicine (Division of Hematology/Oncology), Mayo Clinic, Jacksonville, Florida.
Northfelt DW; Department of Medicine (Division of Hematology/Oncology), Mayo Clinic, Scottsdale, Arizona.
Gray RJ; Department of Surgery, Mayo Clinic, Scottsdale, Arizona.
Hunt KN; Department of Radiology, Mayo Clinic, Rochester, Minnesota.
Conners AL; Department of Radiology, Mayo Clinic, Rochester, Minnesota.
Ingle JN; Department of Oncology, Mayo Clinic, Rochester, Minnesota.
Moyer A; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Weinshilboum R; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota.
Copland JA 3rd; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida.
Wang L; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota.
Goetz MP; Department of Oncology, Mayo Clinic, Rochester, Minnesota. .
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Źródło :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Sep 01; Vol. 27 (17), pp. 4696-4699. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoadjuvant Therapy*
Transplantation, Heterologous*
Xenograft Model Antitumor Assays*
Breast Neoplasms/*drug therapy
Animals ; Breast Neoplasms/surgery ; Female ; Humans ; Mice ; Prospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Development of improved SRC-3 inhibitors as breast cancer therapeutic agents.
Autorzy :
Qin L; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Chen J; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, USA.
Lu D; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, USA.
Jain P; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Yu Y; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Cardenas D; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Peng X; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Yu X; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Xu J; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Wang J; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, USA.
O'Malley BW; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Lonard DM; Department of Molecular and Cellular Biology and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
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Źródło :
Endocrine-related cancer [Endocr Relat Cancer] 2021 Aug 13; Vol. 28 (10), pp. 657-670. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Xenograft Model Antitumor Assays*
Animals ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Epithelial-Mesenchymal Transition ; Female ; Humans ; Mice ; Nuclear Receptor Coactivator 3/antagonists & inhibitors ; Oncogenes
Czasopismo naukowe
Tytuł :
Longitudinal measurement of subcutaneous and intratibial human prostate cancer xenograft growth and response to ionizing radiation by plasma Alu and LINE-1 ctDNA: A comparison to standard methods.
Autorzy :
Mishra A; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zennami K; Department of Urology, The James Buchanan Brady Urologic Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Velarde E; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Thorek DLJ; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Radiology and Biomedical Engineering, Washington University School of Medicine, St. Louis, Missouri, USA.
Yegnasubramanian S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
DeWeese TL; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Urology, The James Buchanan Brady Urologic Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Lupold SE; Department of Urology, The James Buchanan Brady Urologic Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło :
The Prostate [Prostate] 2021 Aug; Vol. 81 (11), pp. 745-753. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Xenograft Model Antitumor Assays*
Alu Elements/*genetics
Circulating Tumor DNA/*blood
Long Interspersed Nucleotide Elements/*genetics
Prostatic Neoplasms/*pathology
Prostatic Neoplasms/*radiotherapy
Animals ; Humans ; Luminescent Measurements/methods ; Male ; Mice ; Mice, Nude ; Subcutaneous Fat/pathology ; Tibia/pathology ; Tumor Burden
Czasopismo naukowe
Tytuł :
Differential Angiogenic Potential of 3-Dimension Spheroid of HNSCC Cells in Mouse Xenograft.
Autorzy :
Choi SY; Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Kang SH; Department of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Oh SY; Department of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Lee KY; Department of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Lee HJ; Department of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Gum S; Binaree Co., Ltd., Daegu 41940, Korea.
Kwon TG; Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Kim JW; Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Lee ST; Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Hong YJ; Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Kim DG; Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Hong SH; Department of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 31; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Squamous Cell/*pathology
Head and Neck Neoplasms/*pathology
Mouth Neoplasms/*pathology
Neovascularization, Pathologic/*pathology
Spheroids, Cellular/*pathology
Xenograft Model Antitumor Assays/*methods
Animals ; Cancer-Associated Fibroblasts/metabolism ; Cancer-Associated Fibroblasts/pathology ; Carcinoma, Squamous Cell/metabolism ; Exosomes/metabolism ; Female ; Head and Neck Neoplasms/metabolism ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mouth Neoplasms/metabolism ; Neovascularization, Pathologic/metabolism ; Primary Cell Culture/methods ; Spheroids, Cellular/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays/standards
Czasopismo naukowe
Tytuł :
Development of humanized mouse with patient-derived xenografts for cancer immunotherapy studies: A comprehensive review.
Autorzy :
Jin KT; Department of Colorectal Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Du WL; Key Laboratory of Gastroenterology of Zhejiang Province, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.; Clinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Lan HR; Department of Breast and Thyroid Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Liu YY; Department of Colorectal Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Mao CS; Department of Colorectal Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Du JL; Department of Colorectal Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Mou XZ; Clinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Jul; Vol. 112 (7), pp. 2592-2606. Date of Electronic Publication: 2021 Jun 05.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Disease Models, Animal*
Immunotherapy*
Xenograft Model Antitumor Assays*
Neoplasms/*therapy
Animals ; Antibodies, Monoclonal/therapeutic use ; Cytokines/metabolism ; Drug Development ; Genetic Engineering ; Graft Rejection/immunology ; Graft vs Host Disease/prevention & control ; Humans ; Immunotherapy, Adoptive/methods ; Intercellular Signaling Peptides and Proteins/metabolism ; Killer Cells, Natural/immunology ; Mice ; Mice, SCID ; Neoplasms/immunology ; Precision Medicine ; Translational Research, Biomedical ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł :
The Establishment of a Fast and Safe Orthotopic Colon Cancer Model Using a Tissue Adhesive Technique.
Autorzy :
Hu HT; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Minimal-Invasive Intervention, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
Wang Z; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Kim MJ; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jiang LS; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Xu SJ; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Minimal-Invasive Intervention, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
Jung J; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Lee E; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Park JH; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Bakheet N; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Gastrointestinal Endoscopy and Liver Unit, Kasr Al-Ainy, Faculty of Medicine, Cairo University, Cairo, Egypt.
Yoon SH; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Kim KY; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Radiology and Research Institute of Clinical Medicine of Jeonbuk National University Hospital, Jeonju, Korea.
Song HY; Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Chang S; Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
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Źródło :
Cancer research and treatment [Cancer Res Treat] 2021 Jul; Vol. 53 (3), pp. 733-743. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Tissue Adhesives*
Colonic Neoplasms/*pathology
Xenograft Model Antitumor Assays/*instrumentation
Animals ; Biomarkers, Tumor/analysis ; Colonic Neoplasms/diagnosis ; HCT116 Cells ; Humans ; Male ; Mice ; Mice, Nude ; Sutures ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe

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