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Tytuł:
Network pharmacology-based research on the effect of Radix Astragali on osteosarcoma and the underlying mechanism.
Autorzy:
Zhang Y; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Wei J; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Kong L; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Song M; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Zhang Y; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Xiao X; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Cao H; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Jin Y; Department of Traumatology and Orthopaedics, Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 15; Vol. 13 (1), pp. 22315. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Osteosarcoma*/drug therapy
Sarcoma*
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Soft Tissue Neoplasms*
Bone Neoplasms*/drug therapy
Humans ; Molecular Docking Simulation ; Network Pharmacology
SCR Organism:
Hygrophila, gastropods
Czasopismo naukowe
Tytuł:
Oral administration of Huanglian-Houpo herbal nanoemulsion loading multiple phytochemicals for ulcerative colitis therapy in mice.
Autorzy:
Wang X; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Fu L; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Cheng W; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chen J; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhang H; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhu H; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhang C; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Fu C; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hu Y; Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Zhang J; State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
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Źródło:
Drug delivery [Drug Deliv] 2023 Dec; Vol. 30 (1), pp. 2204207.
Typ publikacji:
Journal Article
MeSH Terms:
Colitis, Ulcerative*/chemically induced
Colitis, Ulcerative*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Colitis*/drug therapy
Animals ; Mice ; Colon ; Phytochemicals/adverse effects ; Administration, Oral ; Dextran Sulfate/pharmacology ; Disease Models, Animal ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Target Screen of Anti-Hyperuricemia Compounds from Cortex Fraxini In Vivo Based on ABCG2 and Bioaffinity Ultrafiltration Mass Spectrometry.
Autorzy:
Huang X; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221004, China.
Dong W; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221004, China.
Luo X; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221004, China.
Xu L; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221004, China.
Wang Y; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221004, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 01; Vol. 28 (23). Date of Electronic Publication: 2023 Dec 01.
Typ publikacji:
Journal Article
MeSH Terms:
Hyperuricemia*
Gout*
Drugs, Chinese Herbal*/chemistry
Rats ; Animals ; Ultrafiltration ; Ligands ; ATP-Binding Cassette Transporters ; Mass Spectrometry
Czasopismo naukowe
Tytuł:
Quality Evaluation of Peony Petals Based on the Chromatographic Fingerprints and Simultaneous Determination of Sixteen Bioactive Constituents Using UPLC-DAD-MS/MS.
Autorzy:
Li Z; School of Chemical Engineering, Zhengzhou University, Zhengzhou 450001, China.; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Ma Y; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Li F; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Wei Y; Henan Academy of Sciences, Zhongyuan Meigu Microspectrum Technical Service (Henan) Co., Ltd., Luoyang 471002, China.
Zhang L; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Yu L; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Chen L; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Wang X; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Ning E; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Zhang L; Henan Academy of Sciences, Henan Institute of Commercial Science Co., Ltd., Zhengzhou 450002, China.
Wang F; Henan Academy of Sciences, Henan Institute of Commercial Science Co., Ltd., Zhengzhou 450002, China.
Li X; Henan Academy of Sciences, Henan Napu Biotechnology Co., Ltd., Zhengzhou 450002, China.
Chang C; School of Chemical Engineering, Zhengzhou University, Zhengzhou 450001, China.
Fan Y; Henan Academy of Sciences, Henan High Tech Industry Co., Ltd., Zhengzhou 450002, China.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 24; Vol. 28 (23). Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Paeonia*/chemistry
Drugs, Chinese Herbal*/chemistry
Tandem Mass Spectrometry/methods ; Chromatography, High Pressure Liquid/methods ; Tannins/analysis ; Flavonoids/chemistry ; Monoterpenes/analysis
Czasopismo naukowe
Tytuł:
Efficacy and safety of Dachaihu Decoction for acute pancreatitis: Protocol for a systematic review and meta-analysis.
Autorzy:
Xiao X; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Wu X; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Fu Q; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Ren X; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Pang X; Southwest Medical University, Luzhou, Sichuan, China.
Li Y; Southwest Medical University, Luzhou, Sichuan, China.
Zhang Q; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Chen Y; College of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
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Źródło:
PloS one [PLoS One] 2023 May 18; Vol. 18 (5), pp. e0285661. Date of Electronic Publication: 2023 May 18 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pancreatitis*/drug therapy
Pancreatitis*/chemically induced
Drugs, Chinese Herbal*/adverse effects
Humans ; Acute Disease ; Systematic Reviews as Topic ; Meta-Analysis as Topic ; Research Design
Czasopismo naukowe
Tytuł:
Chemical profiling and identification of Radix Cudramiae and their metabolites in rats using an ultra-high-performance liquid chromatography method coupled with time-of-flight tandem mass spectrometry.
Autorzy:
Liu Q; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.; Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, P. R. China.
Pei Y; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.
Wan H; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.; Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, P. R. China.
Wang M; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.; Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, P. R. China.
Liu L; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.; Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, P. R. China.
Li W; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.; Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, P. R. China.
Jin J; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.; Department of TCM Quality, Nanjing Haichang Chinese Medicine Group Corporation, Nanjing, P. R. China.
Liu X; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China.; Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, P. R. China.
Pokaż więcej
Źródło:
Journal of separation science [J Sep Sci] 2023 Feb; Vol. 46 (4), pp. e2200767. Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*/methods
Drugs, Chinese Herbal*/analysis
Rats ; Animals ; Chromatography, High Pressure Liquid/methods ; Rats, Sprague-Dawley ; Gas Chromatography-Mass Spectrometry
Czasopismo naukowe
Tytuł:
QiShenYiQi pills, a Chinese patent medicine, increase bioavailability of atorvastatin by inhibiting Mrp2 expression in rats.
Autorzy:
Ding C; National Clinical Drug Monitoring Center, Hebei General Hospital, Shijiazhuang, China.
Li Y; National Clinical Drug Monitoring Center, Hebei General Hospital, Shijiazhuang, China.
Li X; National Clinical Drug Monitoring Center, Hebei General Hospital, Shijiazhuang, China.
Meng L; Department of Pharmacy, The Second Hospital of Shijiazhuang, Shijiazhuang, China.
Fu R; Graduate School, Hebei Medical University, Shijiazhuang, China.
Wang X; Graduate School, Hebei Medical University, Shijiazhuang, China.
Li Y; National Clinical Drug Monitoring Center, Hebei General Hospital, Shijiazhuang, China.
Ma Y; National Clinical Drug Monitoring Center, Hebei General Hospital, Shijiazhuang, China.
Dong Z; National Clinical Drug Monitoring Center, Hebei General Hospital, Shijiazhuang, China.
Pokaż więcej
Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 185-194.
Typ publikacji:
Journal Article
MeSH Terms:
Herb-Drug Interactions*
ATP-Binding Cassette Transporters/*genetics
Atorvastatin/*pharmacokinetics
Drugs, Chinese Herbal/*pharmacology
Animals ; Area Under Curve ; Biological Availability ; Chromatography, High Pressure Liquid ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacokinetics ; Ileum/metabolism ; Male ; Rats ; Rats, Sprague-Dawley ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
Metabolomics coupled with network pharmacology study on the protective effect of Keguan-1 granules in LPS-induced acute lung injury.
Autorzy:
Chen S; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhou M; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhao X; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Han Y; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Huang Y; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhang L; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Wang J; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Xiao X; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Li P; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of PLA General Hospital, Beijing, China.; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Pokaż więcej
Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 525-534.
Typ publikacji:
Journal Article
MeSH Terms:
Metabolomics*
Acute Lung Injury/*prevention & control
Drugs, Chinese Herbal/*pharmacology
Acute Lung Injury/metabolism ; Acute Lung Injury/pathology ; Animals ; Disease Models, Animal ; Lipopolysaccharides ; Male ; Mice ; Mice, Inbred C57BL ; Network Pharmacology
Czasopismo naukowe
Tytuł:
The sociodemographic characteristics and clinical features of the late-life depression patients: results from the Beijing Anding Hospital mental health big data platform.
Autorzy:
Wang X; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders & Department of Psychiatry, Capital Medical University& Beijing Anding Hospital, Capital Medical University, 5 Ankang Lane, Dewai Avenue, Xicheng District, Beijing, China.
Rao W; Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Chen X; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders & Department of Psychiatry, Capital Medical University& Beijing Anding Hospital, Capital Medical University, 5 Ankang Lane, Dewai Avenue, Xicheng District, Beijing, China.
Zhang X; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders & Department of Psychiatry, Capital Medical University& Beijing Anding Hospital, Capital Medical University, 5 Ankang Lane, Dewai Avenue, Xicheng District, Beijing, China.
Wang Z; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders & Department of Psychiatry, Capital Medical University& Beijing Anding Hospital, Capital Medical University, 5 Ankang Lane, Dewai Avenue, Xicheng District, Beijing, China.
Ma X; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders & Department of Psychiatry, Capital Medical University& Beijing Anding Hospital, Capital Medical University, 5 Ankang Lane, Dewai Avenue, Xicheng District, Beijing, China.
Zhang Q; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders & Department of Psychiatry, Capital Medical University& Beijing Anding Hospital, Capital Medical University, 5 Ankang Lane, Dewai Avenue, Xicheng District, Beijing, China. .
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Źródło:
BMC psychiatry [BMC Psychiatry] 2022 Nov 02; Vol. 22 (1), pp. 677. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Depression*/drug therapy
Depression*/epidemiology
Drugs, Chinese Herbal*
Humans ; Female ; Male ; Aged ; Retrospective Studies ; Big Data ; Mental Health ; Antidepressive Agents/therapeutic use ; Selective Serotonin Reuptake Inhibitors ; Benzodiazepines ; Hospitals
Czasopismo naukowe
Tytuł:
Efficacy and safety of Tanreqing injection combined with antibiotics against Streptococcus pneumoniae pneumonia: A systematic review and meta-analysis.
Autorzy:
Li X; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Wei S; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Ma X; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Li H; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Jing M; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Liu H; Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhao Y; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Pokaż więcej
Źródło:
Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2022 Aug; Vol. 47 (8), pp. 1159-1172. Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms:
Drugs, Chinese Herbal*/adverse effects
Pneumonia*/drug therapy
Anti-Bacterial Agents/adverse effects ; Azithromycin/therapeutic use ; Ceftriaxone/adverse effects ; Humans ; Randomized Controlled Trials as Topic ; Streptococcus pneumoniae
Czasopismo naukowe
Tytuł:
Phytochemical identification of Xiaoer Huanglong Granule and pharmacokinetic study in the rat using its seven major bioactive components.
Autorzy:
Liu J; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
You L; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Yang C; Beijing Shijitan Hospital, Beijing, P. R. China.
Sai N; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Wu H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Sun M; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Cai M; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Peng H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Liang X; Bionorica (Beijing) Technology Development Company, Beijing, P. R. China.
Yin X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Ni J; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, P. R. China.
Pokaż więcej
Źródło:
Journal of separation science [J Sep Sci] 2022 Aug; Vol. 45 (15), pp. 2804-2818. Date of Electronic Publication: 2022 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal*
Tandem Mass Spectrometry*/methods
Administration, Oral ; Animals ; Chromatography, High Pressure Liquid/methods ; Chromatography, Liquid/methods ; Phytochemicals ; Rats ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Protective effects of Re-yan-ning mixture on Streptococcus pneumonia in rats based on network pharmacology.
Autorzy:
Han L; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Kou J; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Hu K; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Wang Y; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Tang Z; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Wu Z; College of Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Song X; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Pokaż więcej
Źródło:
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 209-221.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal/*pharmacology
Inflammation/*drug therapy
Pneumonia, Pneumococcal/*prevention & control
Streptococcus pneumoniae/*drug effects
Animals ; Disease Models, Animal ; Inflammation/microbiology ; Male ; NF-kappa B/metabolism ; Pneumonia, Pneumococcal/microbiology ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Jiang Zhi Granule protects immunological barrier of intestinal mucosa in rats with non-alcoholic steatohepatitis.
Autorzy:
Yu X; Department II of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhang H; Department II of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Pan J; Department II of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zou L; Experiment Center for Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Tang L; Department II of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Miao H; Department II of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zheng P; Department II of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Institute of Digestive Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xing L; Department II of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Institute of Digestive Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Pokaż więcej
Źródło:
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 1359-1368.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal/*pharmacology
Intestinal Mucosa/*drug effects
Non-alcoholic Fatty Liver Disease/*drug therapy
Animals ; Dextran Sulfate ; Diet, High-Fat ; Disease Models, Animal ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/toxicity ; Female ; Hep G2 Cells ; Humans ; Inhibitory Concentration 50 ; Intestinal Mucosa/immunology ; Lethal Dose 50 ; Male ; Myeloid Differentiation Factor 88/genetics ; Non-alcoholic Fatty Liver Disease/immunology ; Rats ; Rats, Sprague-Dawley ; Toll-Like Receptor 4/genetics
Czasopismo naukowe
Tytuł:
Evaluation of the anti-inflammatory and antioxidant pharmcodynamic compoents of naoxintong capsules as a basis of broad spectrum effects.
Autorzy:
Lv B; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Deng L; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xie T; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wei X; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Liu X; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Tan W; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wang X; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.; College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Gao X; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 242-251.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Drugs, Chinese Herbal/*pharmacology
Anti-Inflammatory Agents/administration & dosage ; Antioxidants/administration & dosage ; Capsules ; Cell Line ; Dose-Response Relationship, Drug ; Drugs, Chinese Herbal/administration & dosage ; HEK293 Cells ; Humans ; Inhibitory Concentration 50 ; NF-kappa B/metabolism ; Phosphatidylinositol 3-Kinase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Establishment of an anti-inflammation-based bioassay for the quality control of the 13-component TCM formula (Lianhua Qingwen).
Autorzy:
Chen S; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Yang X; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Wei Z; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Zhang Y; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.; College of Pharmacy and Chemistry, Dali University, Dali, China.
Huang Y; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Shi Z; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Zhang Z; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Wang J; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Zhang H; College of Pharmacy and Chemistry, Dali University, Dali, China.
Ma J; Department of Pharmacy, The Fourth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Xiao X; China Military Institute of Chinese Medicine, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Niu M; Department of Hematology, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Pokaż więcej
Źródło:
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 537-545.
Typ publikacji:
Journal Article
MeSH Terms:
Quality Control*
Anti-Inflammatory Agents/*standards
Biological Assay/*standards
Drugs, Chinese Herbal/*standards
Inflammation Mediators/*antagonists & inhibitors
Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Biological Assay/methods ; Dose-Response Relationship, Drug ; Drug Compounding/methods ; Drug Compounding/standards ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Inflammation Mediators/metabolism ; Mice ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł:
Jiangzhi Ligan Decoction Inhibits GSDMD-Mediated Canonical/Noncanonical Pyroptosis Pathways and Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease.
Autorzy:
Yin K; Medical School, Hunan University of Chinese Medicine, Changsha 410208, China.
Zhou X; Medical School, Hunan University of Chinese Medicine, Changsha 410208, China.
Jiang W; Medical School, Hunan University of Chinese Medicine, Changsha 410208, China.
Wang L; Medical School, Hunan University of Chinese Medicine, Changsha 410208, China.
Dai Z; Medical School, Hunan University of Chinese Medicine, Changsha 410208, China.
Tang B; Medical School, Hunan University of Chinese Medicine, Changsha 410208, China.
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Źródło:
Disease markers [Dis Markers] 2021 Jun 18; Vol. 2021, pp. 9963534. Date of Electronic Publication: 2021 Jun 18 (Print Publication: 2021).
Typ publikacji:
Evaluation Study; Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Diet, High-Fat/*adverse effects
Drugs, Chinese Herbal/*pharmacology
Intracellular Signaling Peptides and Proteins/*metabolism
Non-alcoholic Fatty Liver Disease/*drug therapy
Phosphate-Binding Proteins/*metabolism
Protective Agents/*pharmacology
Pyroptosis/*drug effects
Administration, Oral ; Animals ; Anti-Inflammatory Agents/therapeutic use ; Biomarkers/metabolism ; Drug Administration Schedule ; Drugs, Chinese Herbal/therapeutic use ; Male ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/metabolism ; Protective Agents/therapeutic use ; Pyroptosis/physiology ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
Two new sesquiterpenes from the stems of Tripterygium wilfordii .
Autorzy:
Xiu MX; College of Pharmacy, Beihua University, Jilin 132013, China.
Meng X; College of Pharmacy, Beihua University, Jilin 132013, China.
Li N; Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Wang D; College of Pharmacy, Beihua University, Jilin 132013, China.
Xiong DX; College of Pharmacy, Beihua University, Jilin 132013, China.
Jiang YY; College of Pharmacy, Beihua University, Jilin 132013, China.
Sun YN; College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea.
Chen L; Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Cui L; College of Pharmacy, Beihua University, Jilin 132013, China.
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Źródło:
Journal of Asian natural products research [J Asian Nat Prod Res] 2021 May; Vol. 23 (5), pp. 423-428. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal*/pharmacology
Sesquiterpenes*/pharmacology
Molecular Structure ; Tripterygium
Czasopismo naukowe
Tytuł:
Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.
Autorzy:
Xu ZH; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhu YZ; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Su L; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Tang XY; School of Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410208, China.
Yao C; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Jiao XN; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Hou YF; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Chen X; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Wei LY; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Wang WT; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Wang J; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Gong CY; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhu XD; Center of Technology Experiment, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhang F; Department of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai 200092, China.
Zhu SG; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zou CP; School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
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Źródło:
Mediators of inflammation [Mediators Inflamm] 2021 Apr 01; Vol. 2021, pp. 8856326. Date of Electronic Publication: 2021 Apr 01 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Medicine, Chinese Traditional*
Apoptosis/*drug effects
Carcinoma, Non-Small-Cell Lung/*drug therapy
Drugs, Chinese Herbal/*pharmacology
Granulocytes/*drug effects
Lung Neoplasms/*drug therapy
Myeloid-Derived Suppressor Cells/*drug effects
Animals ; Calgranulin B/physiology ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; Caspase 3/physiology ; Cell Line, Tumor ; Drugs, Chinese Herbal/therapeutic use ; Granulocytes/pathology ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred C57BL ; Myeloid-Derived Suppressor Cells/pathology ; Proto-Oncogene Proteins c-bcl-2/physiology ; STAT3 Transcription Factor/physiology ; Signal Transduction/drug effects ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells.
Autorzy:
Fang W; Spleen and Stomach Research Room, Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350003, P.R. China.
Zhao P; Spleen and Stomach Research Room, Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350003, P.R. China.
Shen A; Academy of Integrative Medicine, Geriatric Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Liu L; Academy of Integrative Medicine, Geriatric Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Chen H; Academy of Integrative Medicine, Geriatric Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Chen Y; Academy of Integrative Medicine, Geriatric Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Peng J; Academy of Integrative Medicine, Geriatric Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Sferra TJ; Department of Pediatrics, Case Western Reserve University School of Medicine, Rainbow Babies and Children's Hospital, Cleveland, OH 44106, USA.
Sankararaman S; Department of Pediatrics, Case Western Reserve University School of Medicine, Rainbow Babies and Children's Hospital, Cleveland, OH 44106, USA.
Luo Y; Spleen and Stomach Research Room, Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350003, P.R. China.
Ke X; Spleen and Stomach Research Room, Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350003, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 Mar; Vol. 23 (3). Date of Electronic Publication: 2021 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal/*pharmacology
Epithelial Cells/*metabolism
Intestinal Mucosa/*metabolism
Lipopolysaccharides/*toxicity
Tight Junctions/*metabolism
Caco-2 Cells ; Epithelial Cells/pathology ; Humans ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/metabolism ; Inflammatory Bowel Diseases/pathology ; Intestinal Mucosa/injuries ; Intestinal Mucosa/pathology ; Tight Junctions/pathology
Czasopismo naukowe
Tytuł:
Chinese Traditional Medicine NiuBeiXiaoHe (NBXH) Extracts Have the Function of Antituberculosis and Immune Recovery in BALB/c Mice.
Autorzy:
Liang Y; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Gong W; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Wang X; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Zhang J; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Ling Y; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Song J; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Wang L; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Liu X; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Wang J; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Yang Y; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Chen S; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Liu J; Guangdong Qifang Pharmaceutical Co., Ltd., Guangzhou 510075, China.
Yang C; Guangdong Qifang Pharmaceutical Co., Ltd., Guangzhou 510075, China.
Luo H; Guangdong Qifang Pharmaceutical Co., Ltd., Guangzhou 510075, China.
Wu X; Army Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, The 8th Medical Centre of Chinese PLA General Hospital, Beijing 100091, China.
Pokaż więcej
Źródło:
Journal of immunology research [J Immunol Res] 2021 Jan 18; Vol. 2021, pp. 6234560. Date of Electronic Publication: 2021 Jan 18 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Antitubercular Agents/*pharmacology
Drugs, Chinese Herbal/*pharmacology
Immunologic Factors/*pharmacology
Mycobacterium tuberculosis/*drug effects
Tuberculosis/*drug therapy
Tuberculosis/*microbiology
Animals ; Antitubercular Agents/administration & dosage ; Bacterial Load ; Biomarkers ; Biopsy ; Computational Biology ; Disease Models, Animal ; Disease Susceptibility ; Drugs, Chinese Herbal/administration & dosage ; Female ; Gene Expression Profiling ; Gene Ontology ; Immunologic Factors/administration & dosage ; Medicine, Chinese Traditional ; Mice ; Mice, Inbred BALB C ; Organ Specificity ; Signal Transduction
Czasopismo naukowe

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