- Tytuł:
-
Coordinate autophagy and mTOR pathway inhibition enhances cell death in
melanoma . - Autorzy:
- Źródło:
- PloS one [PLoS One] 2013; Vol. 8 (1), pp. e55096. Date of Electronic Publication: 2013 Jan 30.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Autophagy/*drug effects
Melanoma /*pathology
Signal Transduction/*drug effects
TOR Serine-Threonine Kinases/*metabolism
Allosteric Regulation/drug effects ; Animals ; Autophagy-Related Protein 7 ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Transformation, Neoplastic ; Drug Synergism ; Gene Knockdown Techniques ; Humans ; Hydroxychloroquine/pharmacology ; Male ; Mice ; Mice, Nude ; Sirolimus/analogs & derivatives ; Sirolimus/pharmacology ; Ubiquitin-Activating Enzymes/deficiency ; Ubiquitin-Activating Enzymes/genetics
Czasopismo naukowe