- Tytuł:
- Astragaloside IV downregulates the expression of MDR1 in Bel‑7402/FU human hepatic cancer cells by inhibiting the JNK/c‑Jun/AP‑1 signaling pathway.
- Autorzy:
- Źródło:
- Molecular medicine reports [Mol Med Rep] 2017 Sep; Vol. 16 (3), pp. 2761-2766. Date of Electronic Publication: 2017 Jul 05.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Antineoplastic Agents /*pharmacology
Down-Regulation/*drug effects
Drug Resistance, Neoplasm/*drug effects
Fluorouracil/*pharmacology
Liver Neoplasms/*drug therapy
Saponins/*pharmacology
Triterpenes/*pharmacology
ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Cell Line, Tumor ; Humans ; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors ; JNK Mitogen-Activated Protein Kinases/metabolism ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Signal Transduction/drug effects ; Transcription Factor AP-1/antagonists & inhibitors ; Transcription Factor AP-1/metabolism
Czasopismo naukowe