Actions of a Novel Bacterial Topoisomerase Inhibitor against Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks.
Autorzy:
Dauda SE; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Collins JA; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Byl JAW; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Lu Y; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. YalowichJC; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 42310, USA. Mitton-Fry MJ; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. Osheroff N; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Department of Medicine (Hematology/Oncology), Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; VA Tennessee Valley Healthcare System, Nashville, TN 37212, USA.
Intronic Polyadenylation in Acquired Cancer Drug Resistance Circumvented by Utilizing CRISPR/Cas9 with Homology-Directed Repair: The Tale of Human DNA Topoisomerase IIα.
Autorzy:
Elton TS; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. Hernandez VA; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. Carvajal-Moreno J; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. Wang X; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. Ipinmoroti D; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. YalowichJC; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Pokaż więcej
Źródło:
Cancers [Cancers (Basel)] 2022 Jun 27; Vol. 14 (13). Date of Electronic Publication: 2022 Jun 27.
Use of CRISPR/Cas9 with homology-directed repair to silence the human topoisomerase IIα intron-19 5' splice site: Generation of etoposide resistance in human leukemia K562 cells.
Autorzy:
Hernandez VA; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America. Carvajal-Moreno J; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America. Wang X; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America. Pietrzak M; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America. YalowichJC; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America. Elton TS; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2022 May 26; Vol. 17 (5), pp. e0265794. Date of Electronic Publication: 2022 May 26 (Print Publication: 2022).
Experimental procedures to identify and validate specific mRNA targets of miRNAs.
Autorzy:
Elton TS; College of Pharmacy, Division of Pharmacology, The Ohio State University, Columbus, OH, USA. YalowichJC; College of Pharmacy, Division of Pharmacology, The Ohio State University, Columbus, OH, USA.
Pokaż więcej
Źródło:
EXCLI journal [EXCLI J] 2015 Jul 02; Vol. 14, pp. 758-90. Date of Electronic Publication: 2015 Jul 02 (Print Publication: 2015).
Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies
