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Wyświetlanie 1-17 z 17
Tytuł :
Treatment and relapse of interstitial lung disease in nivolumab-treated patients with non-small cell lung cancer.
Autorzy :
Sata M; Jichi Medical University, Tochigi, Japan.
Sasaki S; Juntendo University Urayasu Hospital, Urayasu, Japan.
Oikado K; Cancer Institute Hospital, Tokyo, Japan.
Saito Y; Nippon Medical School, Tokyo, Japan.
Tominaga J; Tohoku University School of Medicine, Sendai, Japan.
Sakai F; Saitama Medical University International Medical Center, Hidaka, Japan.
Kato T; Kanagawa Cancer Center, Yokohama, Japan.
Iwasawa T; Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
Kenmotsu H; Shizuoka Cancer Center, Nagaizumi, Japan.
Kusumoto M; National Cancer Center Hospital, Tokyo, Japan.
Baba T; Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
Endo M; Shizuoka Cancer Center, Nagaizumi, Japan.
Fujiwara Y; Mitsui Memorial Hospital, Tokyo, Japan.
Sugiura H; Keio University School of Medicine, Tokyo, Japan.
Yanagawa N; Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Ito Y; Ono Pharmaceutical Co., Ltd., Osaka, Japan.
Sakamoto T; Ono Pharmaceutical Co., Ltd., Osaka, Japan.
Ohe Y; National Cancer Center Hospital, Tokyo, Japan.
Kuwano K; The Jikei University School of Medicine, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Apr; Vol. 112 (4), pp. 1506-1513. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Immunological/*adverse effects
Antineoplastic Agents, Immunological/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Diseases, Interstitial/*chemically induced
Lung Neoplasms/*drug therapy
Nivolumab/*adverse effects
Nivolumab/*therapeutic use
Adult ; Aged ; Antibodies, Monoclonal/adverse effects ; Antibodies, Monoclonal/therapeutic use ; Carcinoma, Non-Small-Cell Lung/pathology ; Female ; Humans ; Japan ; Lung Diseases, Interstitial/pathology ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local/chemically induced ; Neoplasm Recurrence, Local/pathology ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Radiographic features and poor prognostic factors of interstitial lung disease with nivolumab for non-small cell lung cancer.
Autorzy :
Saito Y; Nippon Medical School, Tokyo, Japan.
Sasaki S; Juntendo University Urayasu Hospital, Urayasu, Japan.
Oikado K; Cancer Institute Hospital, Tokyo, Japan.
Tominaga J; Tohoku University School of Medicine, Sendai, Japan.
Sata M; Jichi Medical University, Tochigi, Japan.
Sakai F; Saitama Medical University International Medical Center, Hidaka, Japan.
Kato T; Kanagawa Cancer Center, Yokohama, Japan.
Iwasawa T; Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
Kenmotsu H; Shizuoka Cancer Center, Nagaizumi, Japan.
Kusumoto M; National Cancer Center Hospital, Tokyo, Japan.
Baba T; Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
Endo M; Shizuoka Cancer Center, Nagaizumi, Japan.
Fujiwara Y; Mitsui Memorial Hospital, Tokyo, Japan.
Sugiura H; Keio University School of Medicine, Tokyo, Japan.
Yanagawa N; Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Ito Y; Ono Pharmaceutical Co., Ltd., Osaka, Japan.
Sakamoto T; Ono Pharmaceutical Co., Ltd., Osaka, Japan.
Ohe Y; National Cancer Center Hospital, Tokyo, Japan.
Kuwano K; The Jikei University School of Medicine, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Apr; Vol. 112 (4), pp. 1495-1505. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Antineoplastic Agents, Immunological/*adverse effects
Antineoplastic Agents, Immunological/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Diseases, Interstitial/*chemically induced
Lung Neoplasms/*drug therapy
Nivolumab/*adverse effects
Nivolumab/*therapeutic use
Adult ; Aged ; Carcinoma, Non-Small-Cell Lung/pathology ; Female ; Humans ; Japan ; Lung/drug effects ; Lung/pathology ; Lung Diseases, Interstitial/pathology ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Spread Through Air Spaces Is a Prognostic Factor in Sublobar Resection of Non-Small Cell Lung Cancer.
Autorzy :
Shiono S; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan. Electronic address: .
Endo M; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Suzuki K; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Yarimizu K; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Hayasaka K; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Yanagawa N; Department of Pathology, Yamagata Prefectural Central Hospital, Yamagata, Japan.
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Źródło :
The Annals of thoracic surgery [Ann Thorac Surg] 2018 Aug; Vol. 106 (2), pp. 354-360. Date of Electronic Publication: 2018 Apr 03.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*pathology
Carcinoma, Non-Small-Cell Lung/*surgery
Lung Neoplasms/*pathology
Lung Neoplasms/*surgery
Neoplasm Recurrence, Local/*pathology
Pneumonectomy/*methods
Aged ; Analysis of Variance ; Biopsy, Needle ; Carcinoma, Non-Small-Cell Lung/mortality ; Cohort Studies ; Disease-Free Survival ; Female ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Lung Neoplasms/mortality ; Lymph Nodes/pathology ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Invasiveness/pathology ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/physiopathology ; Neoplasm Staging ; Pneumonectomy/mortality ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Risk Assessment ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.
Autorzy :
Wang D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Sheffield Institute of Translational Neuroscience, University of Sheffield, Sheffield, UK, S1O 2HQ.
Pham NA; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Tong J; Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, Canada.
Sakashita S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Allo G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Kim L; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Yanagawa N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Raghavan V; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Wei Y; Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, Canada.
To C; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Trinh QM; Ontario Institute of Cancer Research, Toronto, ON, Canada.
Starmans MH; Ontario Institute of Cancer Research, Toronto, ON, Canada.
Chan-Seng-Yue MA; Ontario Institute of Cancer Research, Toronto, ON, Canada.
Chadwick D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Li L; Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, Canada.
Zhu CQ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Liu N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Li M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Lee S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Ignatchenko V; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Strumpf D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Taylor P; Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, Canada.
Moghal N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Liu G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.
Boutros PC; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.
Kislinger T; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Pintilie M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Jurisica I; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Department of Computer Science, University of Toronto, Toronto, ON, Canada.
Shepherd FA; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.
McPherson JD; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Muthuswamy L; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Moran MF; Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, ON, Canada.; Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Tsao MS; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
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Źródło :
International journal of cancer [Int J Cancer] 2017 Feb 01; Vol. 140 (3), pp. 662-673. Date of Electronic Publication: 2016 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*genetics
Carcinoma, Non-Small-Cell Lung/*pathology
Heterografts/*pathology
Lung Neoplasms/*genetics
Lung Neoplasms/*pathology
Adult ; Aged ; Animals ; Cell Line, Tumor ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Middle Aged ; Mutation/genetics ; Polymorphism, Single Nucleotide/genetics ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma.
Autorzy :
Stewart EL; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Mascaux C; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Pham NA; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Sakashita S; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Sykes J; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Kim L; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Yanagawa N; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Allo G; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Ishizawa K; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Wang D; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Zhu CQ; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Li M; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Ng C; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Liu N; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Pintilie M; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Martin P; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
John T; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Jurisica I; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Leighl NB; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Neel BG; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Waddell TK; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Shepherd FA; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Liu G; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.
Tsao MS; Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia. .
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Źródło :
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2015 Aug 01; Vol. 33 (22), pp. 2472-80. Date of Electronic Publication: 2015 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*
Mutation*
Signal Transduction*
Antineoplastic Agents/*pharmacology
Biomarkers, Tumor/*analysis
Carcinoma, Non-Small-Cell Lung/*metabolism
ErbB Receptors/*genetics
Lung Neoplasms/*metabolism
Protein Kinase Inhibitors/*pharmacology
Protein-Tyrosine Kinases/*antagonists & inhibitors
Adenocarcinoma/metabolism ; Adenocarcinoma of Lung ; Afatinib ; Aged ; Aged, 80 and over ; Animals ; Antibodies, Monoclonal, Humanized/administration & dosage ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Cetuximab ; Crizotinib ; ErbB Receptors/drug effects ; Erlotinib Hydrochloride ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Heterografts ; Humans ; Lung Neoplasms/drug therapy ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Pyrazoles/administration & dosage ; Pyridines/administration & dosage ; Quinazolines/administration & dosage ; Quinazolinones/administration & dosage ; Up-Regulation
Czasopismo naukowe
Tytuł :
Prognostic impact and initial recurrence site of lymphovascular and visceral pleural invasion in surgically resected stage I non-small-cell lung carcinoma.
Autorzy :
Yanagawa N; Department of Pathology and Laboratory Medicine, Yamagata Prefectural Central Hospital, Yamagata, Japan. />Shiono S
Abiko M
Ogata SY
Sato T
Tamura G
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Źródło :
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery [Eur J Cardiothorac Surg] 2013 Sep; Vol. 44 (3), pp. e200-6. Date of Electronic Publication: 2013 Jun 13.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*pathology
Carcinoma, Non-Small-Cell Lung/*surgery
Lung Neoplasms/*pathology
Lung Neoplasms/*surgery
Adult ; Aged ; Aged, 80 and over ; Analysis of Variance ; Carcinoma, Non-Small-Cell Lung/diagnosis ; Female ; Humans ; Kaplan-Meier Estimate ; Lung Neoplasms/diagnosis ; Lymph Nodes/pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Pleura/pathology ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Human papilloma virus genome is rare in North American non-small cell lung carcinoma patients.
Autorzy :
Yanagawa N; Department of Pathology, University Health Network, Princess Margaret Hospital site and Ontario Cancer Institute, Toronto, Ontario, Canada.
Wang A
Kohler D
Santos Gda C
Sykes J
Xu J
Pintilie M
Tsao MS
Pokaż więcej
Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2013 Mar; Vol. 79 (3), pp. 215-20. Date of Electronic Publication: 2012 Dec 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*virology
Lung Neoplasms/*virology
Papillomaviridae/*isolation & purification
Papillomavirus Infections/*epidemiology
Aged ; Aged, 80 and over ; Cyclin-Dependent Kinase Inhibitor p16 ; DNA, Viral/analysis ; Female ; Genome, Viral/genetics ; Head and Neck Neoplasms/epidemiology ; Head and Neck Neoplasms/virology ; Humans ; Male ; Middle Aged ; Neoplasm Proteins/genetics ; North America ; Papillomaviridae/genetics ; Papillomavirus Infections/virology ; Prevalence ; Uterine Cervical Neoplasms/epidemiology ; Uterine Cervical Neoplasms/virology
Czasopismo naukowe
Tytuł :
Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma.
Autorzy :
Yanagawa N; Department of Pathology and Laboratory Medicine, Yamagata Prefectural Central Hospital, Yamagata, Yamagata, Japan.
Leduc C
Kohler D
Saieg MA
John T
Sykes J
Yoshimoto M
Pintilie M
Squire J
Shepherd FA
Tsao MS
Pokaż więcej
Źródło :
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2012 Oct; Vol. 7 (10), pp. 1513-21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma/*mortality
Carcinoma, Non-Small-Cell Lung/*mortality
Carcinoma, Squamous Cell/*mortality
Lung Neoplasms/*mortality
PTEN Phosphohydrolase/*genetics
Adenocarcinoma/genetics ; Adenocarcinoma/metabolism ; Adult ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; ErbB Receptors/genetics ; Female ; Follow-Up Studies ; Gene Dosage ; Humans ; Immunoenzyme Techniques ; In Situ Hybridization, Fluorescence ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Male ; Middle Aged ; Mutation/genetics ; Neoplasm Staging ; Prognosis ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins p21(ras) ; Survival Rate ; Tissue Array Analysis ; Tumor Suppressor Protein p53/genetics ; ras Proteins/genetics
Czasopismo naukowe
Tytuł :
Characterization of lymphomas developing in immunodeficient mice implanted with primary human non-small cell lung cancer.
Autorzy :
John T; Ludwig Institute for Cancer Research, Austin Health, Melbourne, Australia. />Yanagawa N
Kohler D
Craddock KJ
Bandarchi-Chamkhaleh B
Pintilie M
Sykes J
To C
Li M
Panchal D
Chen W
Shepherd FA
Tsao MS
Pokaż więcej
Źródło :
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2012 Jul; Vol. 7 (7), pp. 1101-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Carcinoma, Non-Small-Cell Lung/*complications
Epstein-Barr Virus Infections/*complications
Herpesvirus 4, Human/*pathogenicity
Lymphocytes, Tumor-Infiltrating/*immunology
Lymphoma, Large B-Cell, Diffuse/*etiology
Lymphoma, Large B-Cell, Diffuse/*mortality
Adenocarcinoma/complications ; Adenocarcinoma/mortality ; Adenocarcinoma/virology ; Adult ; Aged ; Aged, 80 and over ; Animals ; Antigens, Viral/immunology ; Antigens, Viral/metabolism ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/virology ; Carcinoma, Squamous Cell/complications ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/virology ; Female ; Gene Rearrangement ; Herpesvirus 4, Human/genetics ; Humans ; Immunoenzyme Techniques ; Immunophenotyping ; In Situ Hybridization ; Lung Neoplasms/complications ; Lung Neoplasms/mortality ; Lung Neoplasms/virology ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Mice ; Mice, SCID ; Middle Aged ; Mutation/genetics ; Neoplasm Staging ; Oncogene Proteins, Fusion/genetics ; Polymerase Chain Reaction ; Prognosis ; RNA, Viral/genetics ; Survival Rate ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł :
Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.
Autorzy :
Wei Y; Program in Molecular Structure and Function, Hospital For Sick Children, University Health Network, Ontario Cancer Institute/Princess Margaret Hospital, Toronto, Canada.
Tong J
Taylor P
Strumpf D
Ignatchenko V
Pham NA
Yanagawa N
Liu G
Jurisica I
Shepherd FA
Tsao MS
Kislinger T
Moran MF
Pokaż więcej
Źródło :
Journal of proteome research [J Proteome Res] 2011 Jan 07; Vol. 10 (1), pp. 161-74. Date of Electronic Publication: 2010 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasm Transplantation*
Adenocarcinoma/*metabolism
Carcinoma, Non-Small-Cell Lung/*metabolism
Carcinoma, Squamous Cell/*metabolism
Proteome/*metabolism
Animals ; Blotting, Western ; Chromatography, Liquid ; Cluster Analysis ; ErbB Receptors/metabolism ; Humans ; Immunohistochemistry ; Keratin-7/metabolism ; Keratins/metabolism ; Mice ; Mice, Inbred NOD ; Proteome/analysis ; Reproducibility of Results ; Statistics, Nonparametric ; Tandem Mass Spectrometry ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł :
The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer.
Autorzy :
John T; Melbourne Centre for Clinical Sciences, Ludwig Institute for Cancer Research, Melbourne, Australia.
Kohler D
Pintilie M
Yanagawa N
Pham NA
Li M
Panchal D
Hui F
Meng F
Shepherd FA
Tsao MS
Pokaż więcej
Źródło :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2011 Jan 01; Vol. 17 (1), pp. 134-41. Date of Electronic Publication: 2010 Nov 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasm Recurrence, Local*
Xenograft Model Antitumor Assays*
Carcinoma, Non-Small-Cell Lung/*pathology
Lung Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Animals ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/surgery ; ErbB Receptors/genetics ; Female ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/surgery ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Middle Aged ; Multivariate Analysis ; Mutation ; Neoplasm Transplantation ; Predictive Value of Tests ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins p21(ras) ; Risk Factors ; ras Proteins/genetics
Czasopismo naukowe
Tytuł :
MAGE expressions mediated by demethylation of MAGE promoters induce progression of non-small cell lung cancer.
Autorzy :
Yanagawa N; Department of Pathology, Yamagata University Faculty of Medicine, Yamagata, Japan. />Tamura G
Oizumi H
Endoh M
Motoyama T
Pokaż więcej
Źródło :
Anticancer research [Anticancer Res] 2011 Jan; Vol. 31 (1), pp. 171-5.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Antigens, Neoplasm/*genetics
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Neoplasm Proteins/*genetics
Promoter Regions, Genetic/*genetics
Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; DNA, Neoplasm/genetics ; Disease Progression ; Female ; Follow-Up Studies ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/pathology ; Male ; Melanoma-Specific Antigens ; Middle Aged ; Polymerase Chain Reaction ; Prognosis ; RNA, Neoplasm/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Promoter hypermethylation of RASSF1A and RUNX3 genes as an independent prognostic prediction marker in surgically resected non-small cell lung cancers.
Autorzy :
Yanagawa N; Department of Pathology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. />Tamura G
Oizumi H
Kanauchi N
Endoh M
Sadahiro M
Motoyama T
Pokaż więcej
Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2007 Oct; Vol. 58 (1), pp. 131-8. Date of Electronic Publication: 2007 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Cadherins/*genetics
Carcinoma, Non-Small-Cell Lung/*genetics
Core Binding Factor Alpha 3 Subunit/*genetics
Lung Neoplasms/*genetics
Tumor Suppressor Proteins/*genetics
Adult ; Aged ; Aged, 80 and over ; Cadherins/metabolism ; Carcinoma, Non-Small-Cell Lung/physiopathology ; Carcinoma, Non-Small-Cell Lung/surgery ; Core Binding Factor Alpha 3 Subunit/metabolism ; Female ; Genes, Neoplasm ; Genetic Markers ; Humans ; Lung Neoplasms/physiopathology ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Prognosis ; Promoter Regions, Genetic ; Survival Analysis ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
Promoter hypermethylation of tumor suppressor and tumor-related genes in non-small cell lung cancers.
Autorzy :
Yanagawa N; Department of Pathology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Tamura G
Oizumi H
Takahashi N
Shimazaki Y
Motoyama T
Pokaż więcej
Źródło :
Cancer science [Cancer Sci] 2003 Jul; Vol. 94 (7), pp. 589-92.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
DNA Methylation*
Genes, Tumor Suppressor*
Carcinoma, Non-Small-Cell Lung/*genetics
DNA, Neoplasm/*genetics
Lung Neoplasms/*genetics
Neoplasm Proteins/*genetics
Promoter Regions, Genetic/*genetics
Adult ; Age Factors ; Aged ; Apoptosis Regulatory Proteins ; Calcium-Calmodulin-Dependent Protein Kinases/genetics ; DNA Primers ; DNA, Neoplasm/isolation & purification ; Death-Associated Protein Kinases ; Genes, APC ; Humans ; Lung/pathology ; Middle Aged ; Polymerase Chain Reaction ; Reference Values
Czasopismo naukowe
Tytuł :
Frequent epigenetic silencing of the p16 gene in non-small cell lung cancers of tobacco smokers.
Autorzy :
Yanagawa N; Department of Pathology, Yamagata University School of Medicine, 2-2-2 Iida-nishi, Yamagata 990-9585, Japan.
Tamura G
Oizumi H
Takahashi N
Shimazaki Y
Motoyama T
Pokaż więcej
Źródło :
Japanese journal of cancer research : Gann [Jpn J Cancer Res] 2002 Oct; Vol. 93 (10), pp. 1107-13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Silencing*
Genes, p16*
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Smoking/*genetics
Aged ; Carcinoma, Non-Small-Cell Lung/etiology ; Chromosomes, Human, Pair 9 ; DNA Methylation ; Female ; Humans ; Loss of Heterozygosity ; Lung Neoplasms/etiology ; Male ; Middle Aged ; Promoter Regions, Genetic ; Smoking/adverse effects
Czasopismo naukowe
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