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Tytuł:
[ Ra] RaCl 2 nanomicelles showed potent effect against osteosarcoma: targeted alpha therapy in the nanotechnology era.
Autorzy:
Yang Y; Department of Nuclear Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Alencar LMR; Department of Physics, Laboratory of Biophysics and Nanosystems, Federal University of Maranhão, Maranhão, Brazil.
Pijeira MSO; Brazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Nanoradiopharmaceuticals and Synthesis of Novel Radiopharmaceuticals, Rio de Janeiro, Brazil.
Batista BDS; Department of Physics, Laboratory of Biophysics and Nanosystems, Federal University of Maranhão, Maranhão, Brazil.
França ARS; Department of Physics, Laboratory of Biophysics and Nanosystems, Federal University of Maranhão, Maranhão, Brazil.
Rates ERD; Department of Physics, Laboratory of Biophysics and Nanosystems, Federal University of Maranhão, Maranhão, Brazil.
Lima RC; Department of Physics, Laboratory of Biophysics and Nanosystems, Federal University of Maranhão, Maranhão, Brazil.
Gemini-Piperni S; Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Santos-Oliveira R; Brazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Nanoradiopharmaceuticals and Synthesis of Novel Radiopharmaceuticals, Rio de Janeiro, Brazil.; Zona Oeste State University, Laboratory of Radiopharmacy and Nanoradiopharmaceuticals, Rio de Janeiro, Brazil.
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Źródło:
Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 186-191.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Neoplasms/*pathology
Nanoparticles/*chemistry
Osteosarcoma/*pathology
Radiopharmaceuticals/*pharmacology
Radium/*pharmacology
Cell Line, Tumor ; Cell Survival/drug effects ; Chemistry, Pharmaceutical ; Dose-Response Relationship, Drug ; Drug Carriers/chemistry ; Humans ; Micelles ; Particle Size ; Poloxamer/chemistry ; Radioisotopes/administration & dosage ; Radioisotopes/pharmacology ; Radiopharmaceuticals/administration & dosage ; Radium/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protection of zero-valent iron nanoparticles against sepsis and septic heart failure.
Autorzy:
Wang D; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.; School of Chemistry, Xi'an Jiaotong University, No. 28, West Xianning Road, 710049, Xi'an, Shaanxi, China.; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Wang C; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Liang Z; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East, Zhengzhou, China.
Lei W; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Deng C; Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, China.
Liu X; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.
Jiang S; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Zhu Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Zhang S; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Yang W; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China.; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Chen Y; Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, China.
Qiu Y; School of Chemistry, Xi'an Jiaotong University, No. 28, West Xianning Road, 710049, Xi'an, Shaanxi, China.
Meng L; School of Chemistry, Xi'an Jiaotong University, No. 28, West Xianning Road, 710049, Xi'an, Shaanxi, China. .
Yang Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China. .; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No. 3 Hospital, School of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2022 Sep 05; Vol. 20 (1), pp. 405. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Failure*/metabolism
Heart Injuries*
Nanoparticles*
Sepsis*/metabolism
Animals ; Iron ; Mice ; Myocardium/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Alkoxy cyanoacrylate-based nanoparticles with stealth and brain-targeting properties.
Autorzy:
Liu J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Li Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Liu S; Department of Pathology, General Hospital of the PLA Rocket Force, Beijing, China.
Zhang Y; Department of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, China.; East China Institute of Digital Medical Engineering, Shangrao, China.
Luo Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zhuang X; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Wang X; East China Institute of Digital Medical Engineering, Shangrao, China.; Department of Neurosurgery, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, China.
Zhao B; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Xu T; Department of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, China.; Department of Mechanical Engineering, Biomanufacturing Center, Tsinghua University, Beijing, China.
Xu L; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
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Źródło:
Journal of drug targeting [J Drug Target] 2022 Feb; Vol. 30 (2), pp. 219-231. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nanoparticles*/chemistry
Alcohols ; Brain ; Cyanoacrylates ; Drug Delivery Systems
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aging erythrocyte membranes as biomimetic nanometer carriers of liver-targeting chromium poisoning treatment.
Autorzy:
Yao Q; School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, PR China.; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.
Yang G; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.
Wang H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.; School of Pharmacy, Jiamusi University, Jiamusi, PR China.
Liu J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.
Zheng J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.
Lv B; School of Pharmacy, Qiqihar Medical University, Qiqihar, PR China.
Yang M; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.
Yang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.
Gao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China.
Guo Y; School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, PR China.
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Źródło:
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 1455-1465.
Typ publikacji:
Journal Article
MeSH Terms:
Antidotes/*pharmacology
Biomimetic Materials/*metabolism
Chromium/*poisoning
Erythrocyte Membrane/*metabolism
Nanoparticles/*chemistry
Succimer/*pharmacology
Animals ; Antidotes/administration & dosage ; Antidotes/pharmacokinetics ; Chemistry, Pharmaceutical ; Drug Carriers ; Drug Liberation ; Liver/drug effects ; Male ; Mice ; Particle Size ; RAW 264.7 Cells ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Succimer/administration & dosage ; Succimer/pharmacokinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ligand-modified homologous targeted cancer cell membrane biomimetic nanostructured lipid carriers for glioma therapy.
Autorzy:
Chen M; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Cui Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Hao W; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, People's Republic of China.
Fan Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, People's Republic of China.
Zhang J; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Liu Q; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Jiang M; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Yang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, People's Republic of China.
Wang Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Gao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, People's Republic of China.
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Źródło:
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 2241-2255.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Artemisinins/*pharmacology
Brain Neoplasms/*pathology
Glioma/*pathology
Nanoparticles/*chemistry
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacokinetics ; Artemisinins/administration & dosage ; Artemisinins/pharmacokinetics ; Biomimetics ; Blood-Brain Barrier ; Cell Line, Tumor ; Chemistry, Pharmaceutical ; Drug Delivery Systems ; Ligands ; Membrane Lipids/metabolism ; Mice ; Oligopeptides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Hybrid membrane-coated nanosuspensions for multi-modal anti-glioma therapy via drug and antigen delivery.
Autorzy:
Hao W; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Cui Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Fan Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Chen M; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Yang G; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Wang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China. .
Yang M; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Li Z; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Gong W; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China.
Yang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China. .
Gao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, People's Republic of China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2021 Nov 20; Vol. 19 (1), pp. 378. Date of Electronic Publication: 2021 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacokinetics
Antineoplastic Agents*/pharmacology
Nanoparticle Drug Delivery System*
Nanoparticles*/chemistry
Nanoparticles*/metabolism
Brain Neoplasms/*metabolism
Glioma/*metabolism
Animals ; Antigens, Neoplasm/chemistry ; Antigens, Neoplasm/metabolism ; Apoptosis/drug effects ; Biomimetic Materials/chemistry ; Blood-Brain Barrier/metabolism ; Cell Line, Tumor ; Cell Membrane/chemistry ; Cell Membrane/metabolism ; Female ; Humans ; Male ; Mice ; Mice, Inbred ICR ; RAW 264.7 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cancer Cell Membrane-Coated Nanosuspensions for Enhanced Chemotherapeutic Treatment of Glioma.
Autorzy:
Fan Y; College of Pharmacy, Henan University, Kaifeng 475000, China.; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Hao W; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Cui Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Chen M; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Chu X; Department of Stomatology, Fifth Medical Center of Chinese PLA General Hospital, Beijing 100071, China.
Yang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Wang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Gao C; College of Pharmacy, Henan University, Kaifeng 475000, China.; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 23; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents, Phytogenic/*therapeutic use
Brain Neoplasms/*drug therapy
Brain Neoplasms/*pathology
Cell Membrane/*pathology
Glioma/*drug therapy
Glioma/*pathology
Nanoparticles/*chemistry
Animals ; Antineoplastic Agents, Phytogenic/adverse effects ; Antineoplastic Agents, Phytogenic/pharmacology ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/pathology ; Camptothecin/adverse effects ; Camptothecin/analogs & derivatives ; Camptothecin/pharmacology ; Camptothecin/therapeutic use ; Cell Line, Tumor ; Endocytosis/drug effects ; Female ; Humans ; Male ; Mice, Inbred ICR ; Nanoparticles/ultrastructure ; Rats ; Suspensions ; Tissue Distribution/drug effects ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A novel preparative method for nanoparticle albumin-bound paclitaxel with high drug loading and its evaluation both in vitro and in vivo.
Autorzy:
Gao Y; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.; Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Nai J; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.; Wuhan University School of Pharmaceutical Sciences, Wuhan, China.
Yang Z; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zhang J; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.; Pharmaceutical College of Henan University, Kaifeng, China.
Ma S; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zhao Y; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Li H; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Li J; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yang Y; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yang M; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Wang Y; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Gong W; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yu F; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Gao C; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.; Pharmaceutical College of Henan University, Kaifeng, China.
Li Z; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Mei X; Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
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Źródło:
PloS one [PLoS One] 2021 Apr 28; Vol. 16 (4), pp. e0250670. Date of Electronic Publication: 2021 Apr 28 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Albumin-Bound Paclitaxel/*chemistry
Antineoplastic Agents/*chemistry
Nanoparticles/*chemistry
Albumin-Bound Paclitaxel/metabolism ; Albumin-Bound Paclitaxel/therapeutic use ; Animals ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Drug Carriers/chemistry ; Drug Liberation ; Half-Life ; Humans ; Male ; Mice ; Mice, Nude ; Neoplasms/drug therapy ; Particle Size ; Polyethylene Glycols/chemistry ; Rats ; Rats, Wistar ; Tissue Distribution ; Transplantation, Heterologous
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Preparation and Evaluation of a Self-Nanoemulsifying Drug Delivery System Loaded with Heparin Phospholipid Complex.
Autorzy:
Qiu XL; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Fan ZR; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Liu YY; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Wang DF; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Wang SX; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.; Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China.
Li CX; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.; Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China.; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 15; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Delivery Systems*
Emulsions/*chemistry
Heparin/*pharmacology
Nanoparticles/*chemistry
Phospholipids/*chemistry
Administration, Oral ; Animals ; Anticoagulants/pharmacology ; Calorimetry, Differential Scanning ; Heparin/administration & dosage ; Male ; Mice ; Nanoparticles/ultrastructure ; Particle Size ; Proton Magnetic Resonance Spectroscopy ; Solubility ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
T807-modified human serum albumin biomimetic nanoparticles for targeted drug delivery across the blood-brain barrier.
Autorzy:
Gao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Gong W; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yang M; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Chu X; The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China.
Wang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Li Z; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Gao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
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Źródło:
Journal of drug targeting [J Drug Target] 2020 Dec; Vol. 28 (10), pp. 1085-1095. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood-Brain Barrier/*metabolism
Carbolines/*pharmacokinetics
Erythrocyte Membrane/*metabolism
Nanoparticles/*chemistry
Serum Albumin, Human/*chemistry
Animals ; Biomimetics ; Cell Survival ; Chemistry, Pharmaceutical ; Drug Carriers/chemistry ; Endothelial Cells ; Mice ; Phosphatidylethanolamines/chemistry ; Polyethylene Glycols/chemistry ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neuron tau-targeting biomimetic nanoparticles for curcumin delivery to delay progression of Alzheimer's disease.
Autorzy:
Gao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.
Chu X; The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, 100071, China.
Gong W; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.
Zheng J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.
Xie X; General Hospital of Central Theater of the PLA, Wuhan, 430070, China.
Wang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.
Yang M; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.
Li Z; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.
Gao C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China. .
Yang Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2020 May 13; Vol. 18 (1), pp. 71. Date of Electronic Publication: 2020 May 13.
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Alzheimer Disease*
Biomimetic Materials*/chemistry
Biomimetic Materials*/pharmacokinetics
Curcumin*/chemistry
Curcumin*/pharmacokinetics
Curcumin*/pharmacology
Drug Carriers*/chemistry
Drug Carriers*/pharmacokinetics
Nanoparticles/*chemistry
Animals ; Apoptosis/drug effects ; Blood-Brain Barrier/metabolism ; Cell Line ; Disease Models, Animal ; Hippocampus/drug effects ; Hippocampus/pathology ; Humans ; Maze Learning/drug effects ; Mice ; Neurons/metabolism ; Protective Agents/chemistry ; Protective Agents/pharmacokinetics ; Protective Agents/pharmacology ; tau Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Glioma targeting peptide modified apoferritin nanocage.
Autorzy:
Zhai M; a College of Pharmacy of Jiamusi University , Jiamusi Heilongjiang , China.; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Wang Y; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Zhang L; d Clinical Department, Beijing Huilongguan Hospital , Beijng , China.
Liang M; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Fu S; a College of Pharmacy of Jiamusi University , Jiamusi Heilongjiang , China.; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Cui L; a College of Pharmacy of Jiamusi University , Jiamusi Heilongjiang , China.; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Yang M; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Gong W; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Li Z; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Yu L; a College of Pharmacy of Jiamusi University , Jiamusi Heilongjiang , China.
Xie X; c Department of Pharmacy , Wuhan General Hospital of the PLA , Wuhan , China.
Yang C; a College of Pharmacy of Jiamusi University , Jiamusi Heilongjiang , China.
Yang Y; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Gao C; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
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Źródło:
Drug delivery [Drug Deliv] 2018 Nov; Vol. 25 (1), pp. 1013-1024.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoferritins/*pharmacology
Brain Neoplasms/*drug therapy
Glioma/*drug therapy
Nanoparticles/*administration & dosage
Peptides/*pharmacology
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Blood-Brain Barrier/metabolism ; Brain/drug effects ; Brain/metabolism ; Brain Neoplasms/metabolism ; Cell Line ; Cell Line, Tumor ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Endothelial Cells ; Female ; Glioma/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Rats ; Rats, Sprague-Dawley ; Vincristine/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dual-modified natural high density lipoprotein particles for systemic glioma-targeting drug delivery.
Autorzy:
Cui L; a Jiamusi University , Jiamusi , China.; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Wang Y; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Liang M; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Chu X; c 307 Hospital of the PLA , Beijing , China.
Fu S; a Jiamusi University , Jiamusi , China.; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Gao C; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Liu Q; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Gong W; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Yang M; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Li Z; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Yu L; a Jiamusi University , Jiamusi , China.
Yang C; a Jiamusi University , Jiamusi , China.
Su Z; d Weifang People's Hospital , Weifang , China.
Xie X; e Department of Pharmacy , Wuhan General Hospital of the PLA , Wuhan , China.
Yang Y; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
Gao C; b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.
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Źródło:
Drug delivery [Drug Deliv] 2018 Nov; Vol. 25 (1), pp. 1865-1876.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Neoplasms/*drug therapy
Drug Carriers/*chemistry
Glioma/*drug therapy
Lipoproteins, HDL/*chemistry
Nanoparticles/*chemistry
Peptide Fragments/*chemistry
Animals ; Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/pharmacokinetics ; Antineoplastic Agents, Phytogenic/therapeutic use ; Blood-Brain Barrier/metabolism ; Camptothecin/administration & dosage ; Camptothecin/analogs & derivatives ; Camptothecin/pharmacokinetics ; Camptothecin/therapeutic use ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Delivery Systems/methods ; Drug Liberation ; Female ; Human Umbilical Vein Endothelial Cells ; Humans ; Male ; Mice, Inbred ICR
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Titanium dioxide nanoparticles prime a specific activation state of macrophages.
Autorzy:
Huang C; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Sun M; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Yang Y; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Wang F; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Ma X; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Li J; b School of Public Health , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Wang Y; c Institute for Biomedical Engineering & Nano Science , Tongji University School of Medicine , Shanghai , China.
Ding Q; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Ying H; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Song H; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Wu Y; d Key Laboratory of Food Safety Risk Assessment , Ministry of Health , Beijing , China.
Jiang Y; e School of Public Health , Guangzhou Medical University , Guangdong , China.
Jia X; d Key Laboratory of Food Safety Risk Assessment , Ministry of Health , Beijing , China.
Ba Q; b School of Public Health , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Wang H; a Key Laboratory of Food Safety Research , Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.; b School of Public Health , Shanghai Jiao Tong University School of Medicine , Shanghai , China.; f Shanghai Clinical Center , Chinese Academy of Sciences , Shanghai , China.
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Źródło:
Nanotoxicology [Nanotoxicology] 2017 Aug; Vol. 11 (6), pp. 737-750. Date of Electronic Publication: 2017 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
Immunity, Innate/*drug effects
Macrophage Activation/*drug effects
Macrophages/*drug effects
Nanoparticles/*toxicity
Titanium/*toxicity
Animals ; Cell Line ; Cytokines/blood ; Cytokines/immunology ; Immunity, Innate/genetics ; Macrophage Activation/genetics ; Macrophage Activation/immunology ; Macrophages/immunology ; Mice ; Mice, Knockout ; Nanoparticles/chemistry ; Shock, Septic/blood ; Shock, Septic/immunology ; Titanium/chemistry ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ultrasound-responsive nanobubbles contained with peptide-camptothecin conjugates for targeted drug delivery.
Autorzy:
Xie X; a Department of Pharmacy , Wuhan General Hospital of Guangzhou Command , Wuhan , PR China.
Lin W; b Department of Clinical Laboratory , Huangshi Love & Health Hospital of Hubei Province , Huangshi , PR China , and.
Liu H; a Department of Pharmacy , Wuhan General Hospital of Guangzhou Command , Wuhan , PR China.
Deng J; b Department of Clinical Laboratory , Huangshi Love & Health Hospital of Hubei Province , Huangshi , PR China , and.
Chen Y; a Department of Pharmacy , Wuhan General Hospital of Guangzhou Command , Wuhan , PR China.
Liu H; a Department of Pharmacy , Wuhan General Hospital of Guangzhou Command , Wuhan , PR China.
Fu X; a Department of Pharmacy , Wuhan General Hospital of Guangzhou Command , Wuhan , PR China.
Yang Y; c Beijing Institute of Pharmacology and Toxicology , Beijing , PR China.
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Źródło:
Drug delivery [Drug Deliv] 2016 Oct; Vol. 23 (8), pp. 2756-2764. Date of Electronic Publication: 2015 Aug 14.
Typ publikacji:
Journal Article
MeSH Terms:
Camptothecin/*administration & dosage
Camptothecin/*chemistry
Nanoparticles/*administration & dosage
Nanoparticles/*chemistry
Peptides/*administration & dosage
Peptides/*chemistry
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; HeLa Cells ; Humans ; Mice ; Mice, Nude ; Particle Size ; Ultrasonics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Polysaccharide Nanoparticles for Efficient siRNA Targeting in Cancer Cells by Supramolecular pKa Shift.
Autorzy:
Zhang YM; Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China.
Yang Y; Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China.
Zhang YH; Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China.
Liu Y; Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China.; Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071, P. R. China.
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Źródło:
Scientific reports [Sci Rep] 2016 Jul 01; Vol. 6, pp. 28848. Date of Electronic Publication: 2016 Jul 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nanoparticles/*chemistry
Polysaccharides/*chemistry
Prostatic Neoplasms/*genetics
RNA, Small Interfering/*genetics
Animals ; Cell Line, Tumor ; Cell Survival/genetics ; Cyclodextrins/chemistry ; Drug Delivery Systems/methods ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Hyaluronic Acid/chemistry ; Hydrogen-Ion Concentration ; Male ; Mice ; Microscopy, Fluorescence ; NIH 3T3 Cells ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/therapy ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Preparation, characterization and pulmonary pharmacokinetics of a new inhalable zanamivir dry powder.
Autorzy:
Cai X; a Beijing Institute of Pharmacology and Toxicology , Beijing , P.R. China .; b Wuhan Institute of Technology , Wuhan , P.R. China .
Yang Y; a Beijing Institute of Pharmacology and Toxicology , Beijing , P.R. China .
Xie X; a Beijing Institute of Pharmacology and Toxicology , Beijing , P.R. China .; c Department of Pharmacy , Wuhan General Hospital of Guangzhou Military Command , Wuhan , P.R. China , and.
Yu F; a Beijing Institute of Pharmacology and Toxicology , Beijing , P.R. China .
Yang Y; a Beijing Institute of Pharmacology and Toxicology , Beijing , P.R. China .
Yang Z; a Beijing Institute of Pharmacology and Toxicology , Beijing , P.R. China .
Zhang T; d Changzhi Medical College , Changzhi , P.R. China.
Mei X; a Beijing Institute of Pharmacology and Toxicology , Beijing , P.R. China .
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Źródło:
Drug delivery [Drug Deliv] 2016 Jul; Vol. 23 (6), pp. 1962-71. Date of Electronic Publication: 2015 Jun 11.
Typ publikacji:
Journal Article
MeSH Terms:
Dry Powder Inhalers/*methods
Lung/*drug effects
Nanoparticles/*chemistry
Zanamivir/*administration & dosage
Zanamivir/*pharmacokinetics
Administration, Inhalation ; Animals ; Chemistry, Pharmaceutical ; Lung/chemistry ; Mannitol ; Optical Imaging ; Rats ; X-Ray Diffraction ; Zanamivir/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cell-penetrating peptide-doxorubicin conjugate loaded NGR-modified nanobubbles for ultrasound triggered drug delivery.
Autorzy:
Lin W; a Department of Clinical Laboratory , Huangshi Love & Health Hospital of Hubei Province , Huangshi , People's Republic of China .
Xie X; b Department of Pharmacy , Wuhan General Hospital of Guangzhou Military Command , Wuhan , People's Republic of China , and.
Deng J; a Department of Clinical Laboratory , Huangshi Love & Health Hospital of Hubei Province , Huangshi , People's Republic of China .
Liu H; b Department of Pharmacy , Wuhan General Hospital of Guangzhou Military Command , Wuhan , People's Republic of China , and.
Chen Y; b Department of Pharmacy , Wuhan General Hospital of Guangzhou Military Command , Wuhan , People's Republic of China , and.
Fu X; b Department of Pharmacy , Wuhan General Hospital of Guangzhou Military Command , Wuhan , People's Republic of China , and.
Liu H; b Department of Pharmacy , Wuhan General Hospital of Guangzhou Military Command , Wuhan , People's Republic of China , and.
Yang Y; c Department of Pharmacy , Beijing Institute of Pharmacology and Toxicology , Beijing , People's Republic of China.
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Źródło:
Journal of drug targeting [J Drug Target] 2016; Vol. 24 (2), pp. 134-46. Date of Electronic Publication: 2015 Jul 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell-Penetrating Peptides/*administration & dosage
Doxorubicin/*administration & dosage
Nanoparticles/*administration & dosage
Oligopeptides/*administration & dosage
Animals ; Cell Line, Tumor ; Drug Delivery Systems/methods ; Female ; Fibrosarcoma/drug therapy ; Humans ; MCF-7 Cells ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Ultrasonics/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preparation and in vitro evaluation of thienorphine-loaded PLGA nanoparticles.
Autorzy:
Yang Y; a Beijing Institute of Pharmacology and Toxicology , Beijing , PR China and.
Xie XY; a Beijing Institute of Pharmacology and Toxicology , Beijing , PR China and.; b Wuhan General Hospital of Guangzhou Military Command , Wuhan , PR China.
Mei XG; a Beijing Institute of Pharmacology and Toxicology , Beijing , PR China and.
Pokaż więcej
Źródło:
Drug delivery [Drug Deliv] 2016; Vol. 23 (3), pp. 787-93. Date of Electronic Publication: 2014 May 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Buprenorphine/*analogs & derivatives
Lactic Acid/*chemistry
Nanoparticles/*administration & dosage
Nanoparticles/*chemistry
Polyglycolic Acid/*chemistry
Administration, Oral ; Animals ; Biological Availability ; Buprenorphine/administration & dosage ; Buprenorphine/chemistry ; Caco-2 Cells ; Chemistry, Pharmaceutical/methods ; Chitosan/chemistry ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Excipients/chemistry ; Humans ; Male ; Particle Size ; Polylactic Acid-Polyglycolic Acid Copolymer ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Peptide p160-coated silica nanoparticles applied in photodynamic therapy.
Autorzy:
Yang Y; National Center for Nanoscience and Technology, No. 11, Bei Yi Tiao Institution Beijing, 100190 (China), Fax: (+86) 10-82612629.
Wang A
Jia Y
Brezesinski G
Dai L
Zhao J
Li J
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2014 Aug; Vol. 9 (8), pp. 2126-31. Date of Electronic Publication: 2014 Jun 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nanoparticles*
Photochemotherapy*
Peptides/*chemistry
Silicon Dioxide/*chemistry
Human Umbilical Vein Endothelial Cells ; Humans ; MCF-7 Cells ; Microscopy, Electron, Transmission ; Perylene/administration & dosage ; Perylene/analogs & derivatives ; Photosensitizing Agents/administration & dosage ; Quinones/administration & dosage ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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