Autor: "Ydegaard, Rikke" - OpacWWW

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Tytuł:: The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.
Autorzy:: Ydegaard R; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.
Andersen H; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.
Oxlund CS; Department of Endocrinology, Odense University Hospital, Odense, Denmark.
Jacobsen IA; Department of Endocrinology, Odense University Hospital, Odense, Denmark.
Hansen PBL; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.; Cardiovascular and Metabolic Disease, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
Jürgensen JF; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.
Peluso AA; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.
Vanhoutte PM; Department of Pharmacology and Pharmacy, Hong Kong University, China.
Staehr M; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.
Svenningsen P; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.
Jensen BL; Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense C, Denmark.; Pokaż więcej
Źródło:: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2019 Jan; Vol. 225 (1), pp. e13189. Date of Electronic Publication: 2018 Oct 11.
Typ publikacji:: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amiloride/*pharmacology
Endothelial Cells/*drug effects
Epithelial Sodium Channels/*metabolism
Nitric Oxide Synthase Type III/*metabolism
Acid Sensing Ion Channel Blockers/pharmacology ; Amiloride/analogs & derivatives ; Animals ; Blood Pressure/drug effects ; Diabetes Mellitus, Type 1 ; Diabetes Mellitus, Type 2 ; Endothelial Cells/metabolism ; Gene Expression Regulation/drug effects ; Humans ; Hypertension/drug therapy ; Mice ; Mice, Knockout ; Nitric Oxide Synthase Type III/genetics

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