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Tytuł :
IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1α and VEGF Expression in Vascular Endothelial Cells.
Autorzy :
Liu J; The Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China; The Department of Physiology and Pathological Physiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Wang W; The Department of Physiology and Pathological Physiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Wang L; The Department of Physiology and Pathological Physiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Chen S; The Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Tian B; Department of Thoracic Surgery, Beijing Chao-Yang Hospital, Capital Medical University & Beijing Institute of Respiratory Medicine, Beijing, China.
Huang K; Department of Respiratory and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University & Beijing Institute of Respiratory Medicine, Beijing, China.
Corrigan CJ; Faculty of Life Sciences & Medicine, School of Immunology & Microbial Sciences, Department of Inflammation Biology, Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, UK.
Ying S; The Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Wang W; The Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. Electronic address: .
Wang C; The Department of Respirology, Capital Medical University, Beijing, China.
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Źródło :
EBioMedicine [EBioMedicine] 2018 Jul; Vol. 33, pp. 196-210. Date of Electronic Publication: 2018 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells/*cytology
Hypertension, Pulmonary/*metabolism
Hypoxia/*complications
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Interleukin-1 Receptor-Like 1 Protein/*metabolism
Interleukin-33/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Animals ; Cell Adhesion ; Cell Proliferation ; Cells, Cultured ; Disease Models, Animal ; Endothelial Cells/metabolism ; Humans ; Hypertension, Pulmonary/etiology ; Hypoxia/metabolism ; Male ; Mice ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/metabolism ; Vascular Remodeling
Czasopismo naukowe
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