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Tytuł :
Exosomal miR-22-3p from human umbilical cord blood-derived mesenchymal stem cells protects against lipopolysaccharid-induced acute lung injury.
Autorzy :
Zheng Y; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Liu J; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Chen P; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Lin L; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Luo Y; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Ma X; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Lin J; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Shen Y; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Zhang L; Department of Neonatology, the Affiliated Fuzhou Children Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119004. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Lung Injury/*pathology
Exosomes/*metabolism
Fetal Blood/*cytology
Mesenchymal Stem Cells/*metabolism
MicroRNAs/*metabolism
Protective Agents/*metabolism
Acute Lung Injury/chemically induced ; Adult ; Animals ; Apoptosis ; Base Sequence ; Cell Line ; Cell Proliferation ; Disease Models, Animal ; Disease Progression ; Frizzled Receptors/metabolism ; Gene Silencing ; Humans ; Inflammation/pathology ; Lipopolysaccharides ; Male ; Oxidative Stress ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Autorzy :
Li J; Department of Internal Medicine, Jiangxi Chest Hospital, Nanchang 330006, China.
Zhang X; Department of Internal Medicine, Jiangxi Chest Hospital, Nanchang 330006, China.
Wang T; Department of Thoracic Surgery, Jiangxi Chest Hospital, Nanchang 330006, China.
Li J; Department of Internal Medicine, Jiangxi Chest Hospital, Nanchang 330006, China.
Su Q; Medical Department, Jiangxi Chest Hospital, Nanchang 330006, China.
Zhong C; Department of Internal Medicine, Jiangxi Chest Hospital, Nanchang 330006, China.
Chen Z; Department of Thoracic Surgery, Jiangxi Chest Hospital, Nanchang 330006, China. Electronic address: .
Liang Y; Department of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, 410004, Hunan, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119085. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Journal Article
MeSH Terms :
Extracellular Matrix/*metabolism
Fibroblasts/*cytology
HMGB1 Protein/*metabolism
MicroRNAs/*genetics
NF-kappa B/*metabolism
Pulmonary Fibrosis/*pathology
RNA, Long Noncoding/*genetics
Case-Control Studies ; Cell Proliferation ; Fibroblasts/metabolism ; Gene Expression Regulation ; HMGB1 Protein/genetics ; Humans ; Lung/cytology ; Lung/metabolism ; NF-kappa B/genetics ; Pulmonary Fibrosis/genetics ; Pulmonary Fibrosis/metabolism ; Signal Transduction ; Transforming Growth Factor beta1/genetics ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł :
Altered miRNA expression profiling in enamel organ of fluoride affected rat embryos.
Autorzy :
Weng Q; Department of Preventive Dentistry, Shanghai Stomatological Hospital, Fudan University, Shanghai, China; Oral Biomedical Engineering Laboratory, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Yi F; Department of Preventive Dentistry, Shanghai Stomatological Hospital, Fudan University, Shanghai, China; Oral Biomedical Engineering Laboratory, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Yu Y; Department of Preventive Dentistry, Shanghai Stomatological Hospital, Fudan University, Shanghai, China; Oral Biomedical Engineering Laboratory, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Ge S; Department of Preventive Dentistry, Shanghai Stomatological Hospital, Fudan University, Shanghai, China; Oral Biomedical Engineering Laboratory, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Liu S; Oral Biomedical Engineering Laboratory, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Zhang Y; Department of Preventive Dentistry, Shanghai Stomatological Hospital, Fudan University, Shanghai, China; Oral Biomedical Engineering Laboratory, Shanghai Stomatological Hospital, Fudan University, Shanghai, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Mar 01; Vol. 210, pp. 111876. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs*
Enamel Organ/*drug effects
Fluorides/*toxicity
Gene Expression Regulation, Developmental/*drug effects
Animals ; Embryo, Mammalian ; Enamel Organ/embryology ; Enamel Organ/metabolism ; Female ; Fluorosis, Dental ; Rats, Wistar ; Transcriptome/drug effects
Czasopismo naukowe
Tytuł :
Identification and characterization of miRNA expression profiles across five tissues in giant panda.
Autorzy :
Wang C; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Li F; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), China West Normal University, Nanchong, Sichuan 637002, China.
Deng L; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Li M; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Wei M; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Zeng B; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Wu K; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Xu Z; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Wei R; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Wei L; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Liu W; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Zhang S; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Xu L; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Huang Y; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Li D; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China.
Li Y; Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, College of Life Science and Technology, Foshan University, Foshan, Guangdong 528231, China. Electronic address: .
Zhang H; China Conservation and Research Center of Giant Panda, Key Laboratory of SFGA on Conservation Biology of Rare Animals in The Giant Panda National Park (CCRCGP), Dujiangyan, Sichuan, 611830, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145206. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs/*genetics
Ursidae/*genetics
Animals ; Female ; Gene Expression Profiling ; Male ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Effects of seasonal ambient heat stress on expression of microRNAs in the mammary gland of Holstein cows.
Autorzy :
Fan C; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China.
Hu R; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China.
Fan H; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China.
Yang Y; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China.
Gong B; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China.
Zhang S; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China.
Ding J; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China.
Su Y; Bright Farming Co., Ltd., Shanghai, 200436, People's Republic of China.
Zhuo Z; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China. .
Cheng J; College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, People's Republic of China. .
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Źródło :
International journal of biometeorology [Int J Biometeorol] 2021 Feb; Vol. 65 (2), pp. 235-246. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Heat Stress Disorders*/genetics
Heat Stress Disorders*/veterinary
MicroRNAs*/genetics
Animals ; Cattle/genetics ; Female ; Gene Expression Profiling ; Heat-Shock Response/genetics ; Seasons
Czasopismo naukowe
Tytuł :
A multiplex and fast detection platform for microRNAs based on a self-priming microfluidic chip and duplex-specific nuclease.
Autorzy :
Zou Z; Research Centre for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou, 310023, P. R. China. .
Liu Y
Xia L
Hu Z
Yin J
Mu Y
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Źródło :
The Analyst [Analyst] 2021 Jan 21; Vol. 146 (2), pp. 628-635. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
MeSH Terms :
Lab-On-A-Chip Devices*
Biosensing Techniques/*instrumentation
MicroRNAs/*analysis
Ribonucleases/*metabolism
Base Sequence ; DNA Probes/genetics ; DNA Probes/metabolism ; Hep G2 Cells ; Humans ; MCF-7 Cells ; MicroRNAs/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
MicroRNA-135a in ABCA1-labeled Exosome is a Serum Biomarker Candidate for Alzheimer's Disease.
Autorzy :
Liu CG; Clinical Laboratory of Xuanwu Hospital, Captital Medcial University, Beijing 100053, China.
Meng S; State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Beijing 102206, China.
Li Y; Clinical Laboratory of Air Force General Hospital, Chinese People's Liberation Army, Beijing 100142, China.
Lu Y; Clinical Laboratory of Xuanwu Hospital, Captital Medcial University, Beijing 100053, China.
Zhao Y; Clinical Laboratory of Xuanwu Hospital, Captital Medcial University, Beijing 100053, China.
Wang PC; Clinical Laboratory of Xuanwu Hospital, Captital Medcial University, Beijing 100053, China.
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Źródło :
Biomedical and environmental sciences : BES [Biomed Environ Sci] 2021 Jan 20; Vol. 34 (1), pp. 19-28.
Typ publikacji :
Journal Article
MeSH Terms :
ATP Binding Cassette Transporter 1*/blood
ATP Binding Cassette Transporter 1*/cerebrospinal fluid
Exosomes*
Cognitive Dysfunction/*blood
MicroRNAs/*blood
Aged ; Aged, 80 and over ; Alzheimer Disease/blood ; Alzheimer Disease/cerebrospinal fluid ; Animals ; Biomarkers/blood ; Biomarkers/cerebrospinal fluid ; Cell Line ; Cognitive Dysfunction/cerebrospinal fluid ; Erythrocytes/metabolism ; Female ; Humans ; Leukocytes/metabolism ; Male ; Mice, Transgenic ; Neurons/metabolism
Czasopismo naukowe
Tytuł :
Synergism of HPV and MNNG repress miR-218 promoting Het-1A cell malignant transformation by targeting GAB2.
Autorzy :
Zhang Y; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
Zheng Y; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
Pan E; Huai'an Center for Disease Control and Prevention, Huai'an, 223001, Jiangsu, China. Electronic address: .
Zhao C; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
Zhang H; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
Liu R; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
Wang S; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
Pu Y; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
Yin L; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2021 Jan 15; Vol. 447, pp. 152635. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Signal Transducing/*metabolism
Methylnitronitrosoguanidine/*administration & dosage
Methylnitronitrosoguanidine/*metabolism
MicroRNAs/*antagonists & inhibitors
MicroRNAs/*metabolism
Papillomaviridae/*metabolism
Cell Line ; Humans ; Papillomavirus Infections/metabolism ; Respiratory Mucosa/drug effects ; Respiratory Mucosa/metabolism ; Respiratory Mucosa/virology
Czasopismo naukowe
Tytuł :
hUCB-MSC derived exosomal miR-124 promotes rat liver regeneration after partial hepatectomy via downregulating Foxg1.
Autorzy :
Song XJ; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China; The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China; Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou 730000, China.
Zhang L; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China; The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China; Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou 730000, China.
Li Q; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China; The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China; Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou 730000, China.
Li Y; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China; The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China; Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou 730000, China.
Ding FH; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China; The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China; Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou 730000, China.
Li X; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China; The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China; Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou 730000, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118821. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article
MeSH Terms :
Hepatectomy*
Liver Regeneration/*genetics
Mesenchymal Stem Cells/*cytology
MicroRNAs/*genetics
Nerve Tissue Proteins/*genetics
Animals ; Cell Proliferation/genetics ; Down-Regulation ; Exosomes/metabolism ; Fetal Blood/cytology ; Humans ; Liver Regeneration/physiology ; Male ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Circ_0010220-mediated miR-503-5p/CDCA4 axis contributes to osteosarcoma progression tumorigenesis.
Autorzy :
Li J; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China. Electronic address: .
Zhang F; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei, PR China.
Li H; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Peng F; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Wang Z; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Peng H; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
He J; Department of Orthopedics, General Hospital of the Yangtze River Shipping, Wuhan 430010, Hubei, PR China.
Li Y; Physical Examination Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
He L; Physical Examination Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Wei L; School of Health Sciences, Wuhan University, Wuhan 430014, Hubei, PR China.
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Źródło :
Gene [Gene] 2020 Dec 30; Vol. 763, pp. 145068. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms/*genetics
Cell Cycle Proteins/*genetics
MicroRNAs/*genetics
Osteosarcoma/*genetics
RNA, Circular/*genetics
Animals ; Apoptosis ; Bone Neoplasms/metabolism ; Bone Neoplasms/pathology ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation ; G1 Phase Cell Cycle Checkpoints ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/metabolism ; Osteosarcoma/metabolism ; Osteosarcoma/pathology ; RNA, Circular/metabolism
Czasopismo naukowe
Tytuł :
Identification of Serum microRNA-25 as a novel biomarker for pancreatic cancer.
Autorzy :
Yu Y; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center.
Tong Y; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center.
Zhong A; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center.
Wang Y; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center.
Lu R; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Guo L; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Dec 24; Vol. 99 (52), pp. e23863.
Typ publikacji :
Journal Article
MeSH Terms :
Pancreatic Neoplasms*/blood
Pancreatic Neoplasms*/diagnosis
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
CA-19-9 Antigen/*blood
MicroRNAs/*blood
Risk Assessment/*methods
Biomarkers, Tumor/blood ; Diagnosis, Differential ; Early Detection of Cancer ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Diagnostic value of microRNA-25 in patients with non-small cell lung cancer in Chinese population: A systematic review and meta-analysis.
Autorzy :
Li C; Geriatric Pulmonary Department, Chongzhou People's Hospital, 318 Yongkang east road, Chengdu City, Sichuan Province, China.
Sun L
Zhou H
Yang Y
Wang Y
She M
Chen J
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Dec 18; Vol. 99 (51), pp. e23425.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*diagnosis
Lung Neoplasms/*diagnosis
MicroRNAs/*blood
Asian Continental Ancestry Group ; Biomarkers, Tumor ; Carcinoma, Non-Small-Cell Lung/ethnology ; China ; Humans ; Lung Neoplasms/ethnology ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
The N-glycome regulates the endothelial-to-hematopoietic transition.
Autorzy :
Kasper DM; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
Hintzen J; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
Wu Y; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
Ghersi JJ; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
Mandl HK; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
Salinas KE; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
Armero W; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
He Z; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.
Sheng Y; Department of Chemistry, University of California, Davis, CA 95616, USA.
Xie Y; Department of Chemistry, University of California, Davis, CA 95616, USA.
Heindel DW; Biomedical Chemistry Institute, Department of Chemistry, New York University, New York, NY 10003, USA.
Park EJ; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA.
Sessa WC; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA.
Mahal LK; Biomedical Chemistry Institute, Department of Chemistry, New York University, New York, NY 10003, USA.; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada.
Lebrilla C; Department of Chemistry, University of California, Davis, CA 95616, USA.
Hirschi KK; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA. .; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Developmental Genomics Center, Cell Biology Department, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
Nicoli S; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA. .; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2020 Dec 04; Vol. 370 (6521), pp. 1186-1191. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Transdifferentiation*
Endothelial Cells/*cytology
Glycoproteins/*metabolism
Hematopoietic Stem Cells/*cytology
MicroRNAs/*physiology
Polysaccharides/*biosynthesis
ADAM10 Protein/genetics ; ADAM10 Protein/metabolism ; Animals ; Animals, Genetically Modified ; Cell Lineage ; Endothelial Cells/metabolism ; Genes, Reporter ; Glycomics ; Glycosylation ; Hematopoietic Stem Cells/metabolism ; Mannosyltransferases/metabolism ; MicroRNAs/genetics ; Sialyltransferases/metabolism ; Zebrafish
Czasopismo naukowe
Tytuł :
Transfer of miR-15a-5p by placental exosomes promotes pre-eclampsia progression by regulating PI3K/AKT signaling pathway via CDK1.
Autorzy :
Wang Y; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province 110004, PR China.
Du X; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province 110004, PR China.
Wang J; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province 110004, PR China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Dec; Vol. 128, pp. 277-286. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
CDC2 Protein Kinase/*genetics
Exosomes/*genetics
MicroRNAs/*genetics
Phosphatidylinositol 3-Kinases/*genetics
Placenta/*metabolism
Pre-Eclampsia/*genetics
Proto-Oncogene Proteins c-akt/*genetics
Adult ; Animals ; Apoptosis/genetics ; Cell Movement/genetics ; Cell Proliferation/genetics ; Down-Regulation/genetics ; Female ; Humans ; Male ; Mice ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/genetics ; Trophoblasts/metabolism ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
MiR-26a targets EphA2 to resist intracellular Listeria monocytogenes in macrophages.
Autorzy :
Zhang J; School of Pharmaceutical Sciences and Innovative Drug Research Center, Chongqing University, Chongqing, 401331, China.
Yuan J; Hepato-Pancreato-Biliary Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong province 518036, China. Electronic address: .
Wang L; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Zheng Z; The University of North Carolina at Chapel Hill, USA.
Ran H; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Liu F; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Li F; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Tang X; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Zhang J; School of Pharmaceutical Sciences and Innovative Drug Research Center, Chongqing University, Chongqing, 401331, China.
Ni Q; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Zou L; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Huang Y; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China.
Feng S; Key Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, 510632, China. Electronic address: .
Xia X; School of Pharmaceutical Sciences and Innovative Drug Research Center, Chongqing University, Chongqing, 401331, China. Electronic address: .
Wan Y; School of Pharmaceutical Sciences and Innovative Drug Research Center, Chongqing University, Chongqing, 401331, China; Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China; Chongqing Key Laboratory of Cytomics, Chongqing, 400038, China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Dec; Vol. 128, pp. 69-78. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ephrin-A2/*metabolism
Listeria monocytogenes/*pathogenicity
Listeriosis/*metabolism
Macrophages/*metabolism
Macrophages/*microbiology
MicroRNAs/*metabolism
Animals ; Cell Line ; Cytoplasm/metabolism ; Cytoplasm/microbiology ; Down-Regulation/physiology ; Mice ; Mice, Inbred C57BL ; Phagocytosis/physiology ; RAW 264.7 Cells ; Sequence Analysis, RNA/methods ; Spleen/metabolism ; Spleen/microbiology
Czasopismo naukowe
Tytuł :
[The role of miRNA in kidney development].
Autorzy :
Zhao XQ; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan 430071, China.
Ao Y; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan 430071, China.
Chen HY; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan 430071, China.
Wang H; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan 430071, China.
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Źródło :
Yi chuan = Hereditas [Yi Chuan] 2020 Nov 20; Vol. 42 (11), pp. 1062-1072.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Kidney*/embryology
Kidney Diseases*/genetics
MicroRNAs*/genetics
MicroRNAs*/metabolism
Gene Expression Regulation, Developmental/genetics ; Humans
Czasopismo naukowe
Tytuł :
Zippering DNA Tetrahedral Hyperlink for Ultrasensitive Electrochemical MicroRNA Detection.
Autorzy :
Wan Y
Wang H
Ji J
Kang K
Yang M
Huang Y
Su Y
Ma K
Zhu L
Deng S
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Źródło :
Analytical chemistry [Anal Chem] 2020 Nov 17; Vol. 92 (22), pp. 15137-15144. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosensing Techniques/*methods
DNA/*chemistry
MicroRNAs/*analysis
Cell Line, Tumor ; Electrochemistry ; Humans ; Limit of Detection ; MicroRNAs/chemistry ; Nanostructures/chemistry ; Nucleic Acid Hybridization
Czasopismo naukowe
Tytuł :
High-Efficient Electrochemiluminescence of BCNO Quantum Dot-Equipped Boron Active Sites with Unexpected Catalysis for Ultrasensitive Detection of MicroRNA.
Autorzy :
Sun MF; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P.R. China.
Liu JL; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P.R. China.
Zhou Y; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P.R. China.
Zhang JQ; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P.R. China.
Chai YQ; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P.R. China.
Li ZH; Henan Joint International Research Laboratory of Green Construction of Functional Molecules and Their Bioanalytical Applications, College of Chemistry, Zhengzhou University, Zhengzhou 450001, P.R. China.
Yuan R; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P.R. China.
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Źródło :
Analytical chemistry [Anal Chem] 2020 Nov 03; Vol. 92 (21), pp. 14723-14729. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Limit of Detection*
Boron Compounds/*chemistry
Luminescent Measurements/*methods
MicroRNAs/*analysis
Quantum Dots/*chemistry
Catalysis ; Electrochemistry ; MicroRNAs/chemistry
Czasopismo naukowe
Tytuł :
Human cytomegalovirus protein UL136 activates the IL-6/STAT3 signal through MiR-138 and MiR-34c in gastric cancer cells.
Autorzy :
Shi L; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China.
Fan B; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China.
Chen D; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China.
Guo C; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China.
Xiang H; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China.
Nie Y; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China.
Zhong D; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China. .
Shi X; Department of Gastroenterology, Jinhua People's Hospital, Jinhua, 321000, Zhejiang Province, China. .
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Źródło :
International journal of clinical oncology [Int J Clin Oncol] 2020 Nov; Vol. 25 (11), pp. 1936-1944. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Interleukin-6/*metabolism
MicroRNAs/*metabolism
STAT3 Transcription Factor/*metabolism
Stomach Neoplasms/*metabolism
Stomach Neoplasms/*virology
Viral Proteins/*metabolism
3' Untranslated Regions ; Animals ; Binding Sites ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cytomegalovirus/genetics ; Cytomegalovirus Infections/metabolism ; Cytomegalovirus Infections/pathology ; Gene Expression Regulation, Neoplastic ; Host-Pathogen Interactions ; Humans ; Interleukin-6/genetics ; Male ; Mice, Inbred BALB C ; MicroRNAs/genetics ; STAT3 Transcription Factor/genetics ; Signal Transduction ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
MicroRNA-15b Targets VEGF and Inhibits Angiogenesis in Proliferative Diabetic Retinopathy.
Autorzy :
Yang Y; Department of Endocrinology, The Second People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Liu Y; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Li Y; Department of Endocrinology, The Second People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Chen Z; Institute of Cardiovascular Disease, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xiong Y; Department of Endocrinology, The Second People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Zhou T; Department of Endocrinology, The Second People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Tao W; Department of Endocrinology, The Second People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Xu F; Department of Endocrinology, The Second People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Yang H; Department of Endocrinology, The Second People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Ylä-Herttuala S; Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio; and Heart Center and Gene Therapy Unit, Kuopio University Hospital, Finland.
Chaurasia SS; Ocular Immunology and Angiogenesis Lab, University of Missouri, Columbia, Missouri.
Adam WC; Division of Endocrinology and Metabolism, Department of Medicine, University of Missouri, Columbia, Missouri.; Research Service, Harry S. Truman Memorial Veterans' Hospital, Columbia, Missouri.; Division of Nephrology, Department of Medicine, University of Missouri, Columbia, Missouri.
Yang K; Institute of Cardiovascular Disease, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Nov 01; Vol. 105 (11).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Diabetic Retinopathy/*metabolism
MicroRNAs/*metabolism
Neovascularization, Pathologic/*metabolism
Retina/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Adult ; Aged ; Animals ; Diabetic Retinopathy/pathology ; Female ; HeLa Cells ; Humans ; Male ; Middle Aged ; Neovascularization, Pathologic/pathology ; Rats ; Retina/pathology
Czasopismo naukowe

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