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Tytuł:
Chronic colitis upregulates microRNAs suppressing brain-derived neurotrophic factor in the adult heart.
Autorzy:
Tang Y; Department of Gastroenterology, the First Affiliated Hospital, Guangxi Medical University, Nanning, China.
Kline KT; Division of Gastroenterology, Department of Internal Medicine, The University of Texas Medical Branch at Galveston, Galveston, TX, United States of America.
Zhong XS; Division of Gastroenterology, Department of Internal Medicine, The University of Texas Medical Branch at Galveston, Galveston, TX, United States of America.
Xiao Y; Division of Gastroenterology, Department of Internal Medicine, The University of Texas Medical Branch at Galveston, Galveston, TX, United States of America.; Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, China.
Lian H; Department of Gastroenterology, Binzhou Medical University Hospital, Binzhou, China.
Peng J; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
Liu X; Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, China.
Powell DW; Division of Gastroenterology, Department of Internal Medicine, The University of Texas Medical Branch at Galveston, Galveston, TX, United States of America.
Tang G; Department of Gastroenterology, the First Affiliated Hospital, Guangxi Medical University, Nanning, China.
Li Q; Division of Gastroenterology, Department of Internal Medicine, The University of Texas Medical Branch at Galveston, Galveston, TX, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Sep 20; Vol. 16 (9), pp. e0257280. Date of Electronic Publication: 2021 Sep 20 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Up-Regulation*
Brain-Derived Neurotrophic Factor/*biosynthesis
Brain-Derived Neurotrophic Factor/*genetics
Colitis/*metabolism
MicroRNAs/*biosynthesis
Myocardium/*metabolism
Animals ; Cell Line ; Cell Proliferation ; Disease Models, Animal ; Echocardiography ; Hydrogen Peroxide ; Interleukin-1beta/metabolism ; Male ; MicroRNAs/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł:
Mechanism of lncRNA-ANRIL/miR-181b in autophagy of cardiomyocytes in mice with uremia by targeting ATG5.
Autorzy:
Xu Y; Department of Urology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
Chen J; Department of Urology, Tongde Hospital of Zhejiang Province, Zhejiang, China.
Wang M; Department of Nephrology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
Yu R; Department of Nephrology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
Zou W; Department of Nephrology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
Shen W; Department of Nephrology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
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Źródło:
PloS one [PLoS One] 2021 Sep 01; Vol. 16 (9), pp. e0256734. Date of Electronic Publication: 2021 Sep 01 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy/*genetics
Autophagy-Related Protein 5/*genetics
MicroRNAs/*metabolism
RNA, Long Noncoding/*metabolism
Uremia/*immunology
Animals ; Autophagy-Related Protein 5/metabolism ; Coronary Vessels/cytology ; Coronary Vessels/metabolism ; Disease Models, Animal ; Down-Regulation/immunology ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Exosomes/metabolism ; Humans ; Male ; Mice ; MicroRNAs/genetics ; Microvessels/cytology ; Myocardium/cytology ; Myocardium/immunology ; Myocardium/pathology ; Myocytes, Cardiac/immunology ; Myocytes, Cardiac/pathology ; RNA, Long Noncoding/genetics ; Up-Regulation/immunology ; Uremia/genetics ; Uremia/pathology
Czasopismo naukowe
Tytuł:
Prediction of miRNA targets by learning from interaction sequences.
Autorzy:
Zheng X; Department of Biochemistry and Molecular Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P. R. China.; Department of Clinical Laboratory, the First People's Hospital of Zhangjiagang, Zhangjiagang, Jiangsu, P. R. China.
Chen L; Department of Clinical Laboratory, the First People's Hospital of Zhangjiagang, Zhangjiagang, Jiangsu, P. R. China.
Li X; School of Computer Science, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, P. R. China.
Zhang Y; Department of Biochemistry and Molecular Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P. R. China.
Xu S; Department of Biochemistry and Molecular Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P. R. China.
Huang X; Department of Biochemistry and Molecular Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P. R. China.
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Źródło:
PloS one [PLoS One] 2020 May 05; Vol. 15 (5), pp. e0232578. Date of Electronic Publication: 2020 May 05 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation*
Neural Networks, Computer*
MicroRNAs/*genetics
Algorithms ; Animals ; Computer Simulation ; Humans ; Models, Genetic ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł:
Screening differential miRNAs responsible for permeability increase in HUVECs infected with influenza A virus.
Autorzy:
Zhang S; Scientific Research Center, Beijing University of Chinese Medicine, Beijing, China.
Wu Y; Department of Microbiology and Immunology, School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Xuan Z; Department of Microbiology and Immunology, School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Chen X; Department of Microbiology and Immunology, School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Zhang J; Department of Microbiology and Immunology, School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Ge D; Scientific Research Center, Beijing University of Chinese Medicine, Beijing, China.
Wang X; Department of Microbiology and Immunology, School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
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Źródło:
PloS one [PLoS One] 2017 Oct 23; Vol. 12 (10), pp. e0186477. Date of Electronic Publication: 2017 Oct 23 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Capillary Permeability/*genetics
Influenza A virus/*physiology
MicroRNAs/*physiology
Umbilical Veins/*virology
Gene Expression Profiling ; Human Umbilical Vein Endothelial Cells ; Humans
Czasopismo naukowe
Tytuł:
Characterization of microRNAs of Beta macrocarpa and their responses to Beet necrotic yellow vein virus infection.
Autorzy:
Liu JY; State Key Laboratory for Agro-Biotechnology and Ministry of Agriculture Key Laboratory for Plant Pathology, China Agricultural University, Beijing, P. R. China.
Fan HY; College of Pharmacy, Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.
Wang Y; State Key Laboratory for Agro-Biotechnology and Ministry of Agriculture Key Laboratory for Plant Pathology, China Agricultural University, Beijing, P. R. China.
Zhang YL; State Key Laboratory for Agro-Biotechnology and Ministry of Agriculture Key Laboratory for Plant Pathology, China Agricultural University, Beijing, P. R. China.
Li DW; State Key Laboratory for Agro-Biotechnology and Ministry of Agriculture Key Laboratory for Plant Pathology, China Agricultural University, Beijing, P. R. China.
Yu JL; State Key Laboratory for Agro-Biotechnology and Ministry of Agriculture Key Laboratory for Plant Pathology, China Agricultural University, Beijing, P. R. China.
Han CG; State Key Laboratory for Agro-Biotechnology and Ministry of Agriculture Key Laboratory for Plant Pathology, China Agricultural University, Beijing, P. R. China.
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Źródło:
PloS one [PLoS One] 2017 Oct 16; Vol. 12 (10), pp. e0186500. Date of Electronic Publication: 2017 Oct 16 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Beta vulgaris/*genetics
Beta vulgaris/*virology
MicroRNAs/*genetics
Plant Diseases/*virology
Plant Viruses/*physiology
Beta vulgaris/cytology ; Beta vulgaris/metabolism ; Gene Expression Regulation, Plant ; High-Throughput Nucleotide Sequencing ; Phylogeny ; Plant Growth Regulators/biosynthesis ; Plant Leaves/virology ; Sequence Analysis, RNA ; Signal Transduction
Czasopismo naukowe
Tytuł:
Increased microRNA-93-5p inhibits osteogenic differentiation by targeting bone morphogenetic protein-2.
Autorzy:
Zhang Y; Medical Centre of Hip, Luoyang Orthopaedic-Traumatological Hospital (Orthopaedic Hospital of Henan Province), Luoyang, China.
Wei QS; The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Ding WB; Guangzhou Ginkgo Biotechnology Co., LTD., Guangzhou, China.
Zhang LL; Medical Centre of Hip, Luoyang Orthopaedic-Traumatological Hospital (Orthopaedic Hospital of Henan Province), Luoyang, China.
Wang HC; Medical Centre of Hip, Luoyang Orthopaedic-Traumatological Hospital (Orthopaedic Hospital of Henan Province), Luoyang, China.
Zhu YJ; Medical Centre of Hip, Luoyang Orthopaedic-Traumatological Hospital (Orthopaedic Hospital of Henan Province), Luoyang, China.
He W; The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Chai YN; The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liu YW; Medical Centre of Hip, Luoyang Orthopaedic-Traumatological Hospital (Orthopaedic Hospital of Henan Province), Luoyang, China.
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Źródło:
PloS one [PLoS One] 2017 Aug 10; Vol. 12 (8), pp. e0182678. Date of Electronic Publication: 2017 Aug 10 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Osteogenesis*
Bone Morphogenetic Protein 2/*genetics
Femoral Neck Fractures/*metabolism
Femur Head Necrosis/*metabolism
MicroRNAs/*physiology
Abnormalities, Multiple ; Adult ; Base Sequence ; Binding Sites ; Bone Morphogenetic Protein 2/metabolism ; Female ; Femoral Neck Fractures/complications ; Femoral Neck Fractures/pathology ; Femur Head Necrosis/etiology ; Femur Head Necrosis/pathology ; HEK293 Cells ; Humans ; Limb Deformities, Congenital ; Male ; Mandibulofacial Dysostosis ; Micrognathism ; Middle Aged ; Osteoblasts/physiology ; RNA Interference ; Sequence Analysis, DNA ; Young Adult
SCR Disease Name:
Genee-Wiedemann syndrome
Czasopismo naukowe
Tytuł:
MicroRNA-144-3p inhibits autophagy activation and enhances Bacillus Calmette-Guérin infection by targeting ATG4a in RAW264.7 macrophage cells.
Autorzy:
Guo L; Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, General Hospital of Ningxia Medical University, Yinchuan, China.; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Zhou L; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.; Clinical laboratory, Affiliated Hospital of north china university of science and technology, Tangshan, China.
Gao Q; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Zhang A; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Wei J; Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, General Hospital of Ningxia Medical University, Yinchuan, China.; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Hong D; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Chu Y; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Duan X; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Zhang Y; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America.
Xu G; Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, General Hospital of Ningxia Medical University, Yinchuan, China.; Department of Medical Laboratory, School of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
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Źródło:
PloS one [PLoS One] 2017 Jun 21; Vol. 12 (6), pp. e0179772. Date of Electronic Publication: 2017 Jun 21 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Cysteine Endopeptidases/*metabolism
MicroRNAs/*metabolism
Mycobacterium bovis/*physiology
3' Untranslated Regions ; Animals ; Antagomirs/metabolism ; Anti-Bacterial Agents/pharmacology ; Autophagosomes/metabolism ; Autophagy ; Base Sequence ; Cysteine Endopeptidases/chemistry ; Cysteine Endopeptidases/genetics ; Macrophages/cytology ; Macrophages/metabolism ; Macrophages/microbiology ; Mice ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/genetics ; Microscopy, Electron, Transmission ; Microscopy, Fluorescence ; RAW 264.7 Cells ; Sequence Alignment ; Sirolimus/pharmacology
Czasopismo naukowe
Tytuł:
Discovery of microRNAs during early spermatogenesis in chicken.
Autorzy:
Xu L; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Guo Q; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Chang G; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Qiu L; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Liu X; Poultry Institute, Chinese Academy of Agricultural Sciences, Yangzhou, Jiangsu, China.
Bi Y; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Zhang Y; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Wang H; Poultry Institute, Chinese Academy of Agricultural Sciences, Yangzhou, Jiangsu, China.
Lu W; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Ren L; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Chen Y; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Zhang Y; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Xu Q; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
Chen G; College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
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Źródło:
PloS one [PLoS One] 2017 May 22; Vol. 12 (5), pp. e0177098. Date of Electronic Publication: 2017 May 22 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Spermatogenesis*
High-Throughput Nucleotide Sequencing/*veterinary
Lim Kinases/*genetics
MicroRNAs/*genetics
Sequence Analysis, RNA/*veterinary
Adult Germline Stem Cells/metabolism ; Animals ; Cell Differentiation ; Chickens ; Gene Expression Regulation, Developmental ; Gene Library ; Gene Regulatory Networks ; Male ; MicroRNAs/metabolism ; Spermatogonia/metabolism
Czasopismo naukowe
Tytuł:
MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification.
Autorzy:
Liu J; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).; Department of Metabolism and Endocrinology, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Xiao X; Department of Metabolism and Endocrinology, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Shen Y; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).
Chen L; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).
Xu C; Department of Pathology and Immunology, University of Washington School of Medicine, St. Louis, Missouri, United States of America.
Zhao H; Department of Metabolism and Endocrinology, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Wu Y; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).
Zhang Q; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).
Zhong J; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).
Tang Z; Department of Cardiovascular Medicine, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Liu C; Department of Cardiovascular Medicine, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Zhao Q; Department of Metabolism and Endocrinology, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Zheng Y; Department of Metabolism and Endocrinology, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Cao R; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).; Department of Metabolism and Endocrinology, the First Affiliated Hospital of University of South China, Hengyang, PRC.
Zu X; Institute of Clinical Medicine, the First Affiliated Hospital of University of South China, Hengyang, People's Republic of China (PRC).
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Źródło:
PloS one [PLoS One] 2017 Mar 20; Vol. 12 (3), pp. e0174138. Date of Electronic Publication: 2017 Mar 20 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs/*metabolism
Vascular Calcification/*metabolism
Animals ; Biomarkers/blood ; Cell Line ; Core Binding Factor Alpha 1 Subunit/metabolism ; Coronary Artery Disease/blood ; Coronary Artery Disease/diagnostic imaging ; Coronary Vessels/diagnostic imaging ; Disease Models, Animal ; Humans ; Male ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Osteogenesis/physiology ; Osteoprotegerin/genetics ; Osteoprotegerin/metabolism ; PTEN Phosphohydrolase/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation ; Vascular Calcification/diagnostic imaging ; Vascular Calcification/pathology
Czasopismo naukowe
Tytuł:
A functional variant in the 3'-UTR of VEGF predicts the 90-day outcome of ischemic stroke in Chinese patients.
Autorzy:
Zhao J; Department of Neurology, Minhang district central hospital, Shanghai, China.
Bai Y; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China.
Jin L; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China.; School of Life Sciences, Fudan University, Shanghai, China.
Weng Y; Department of Neurology, Minhang district central hospital, Shanghai, China.
Wang Y; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China.
Wu H; Department of Neurology, Minhang district central hospital, Shanghai, China.
Li X; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China.
Huang Y; Luoxin Biotechnology Company at Shanghai, Pudong New Area, Shanghai, China.
Wang S; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2017 Feb 24; Vol. 12 (2), pp. e0172709. Date of Electronic Publication: 2017 Feb 24 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
3' Untranslated Regions*
Polymorphism, Single Nucleotide*
Brain Ischemia/*genetics
MicroRNAs/*genetics
Stroke/*genetics
Vascular Endothelial Growth Factor A/*genetics
Adult ; Aged ; Aged, 80 and over ; Alleles ; Base Sequence ; Binding Sites ; Brain Ischemia/diagnosis ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Case-Control Studies ; Female ; Gene Expression ; Genetic Predisposition to Disease ; Humans ; Linkage Disequilibrium ; Male ; MicroRNAs/metabolism ; Middle Aged ; Multivariate Analysis ; Prognosis ; Risk ; Severity of Illness Index ; Stroke/diagnosis ; Stroke/metabolism ; Stroke/pathology ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł:
Downregulated miR-29a/b/c during Contact Inhibition Stage Promote 3T3-L1 Adipogenesis by Targeting DNMT3A.
Autorzy:
Zhu Y; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Zheng G; CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai, China.
Wang H; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Jia Y; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Zhang Y; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Tang Y; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Li W; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Fan Y; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Zhang X; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Liu Y; Henan Provincial Luoyang Orthopedic-Traumatological Hospital (Henan Provincial Orthopedic Hospital), Luoyang, Henan, China.
Liu S; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2017 Jan 23; Vol. 12 (1), pp. e0170636. Date of Electronic Publication: 2017 Jan 23 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Down-Regulation*
Adipogenesis/*genetics
DNA (Cytosine-5-)-Methyltransferases/*metabolism
MicroRNAs/*genetics
3T3-L1 Cells ; Animals ; Cell Differentiation ; DNA Methyltransferase 3A ; Gene Expression Profiling ; HEK293 Cells ; Humans ; Mice ; Signal Transduction
Czasopismo naukowe
Tytuł:
Defining Transcriptional Regulatory Mechanisms for Primary let-7 miRNAs.
Autorzy:
Gaeta X; Broad Stem Cell Center, University of California Los Angeles, Los Angeles, California, United States of America.; Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America.
Le L; Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America.
Lin Y; Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America.
Xie Y; Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America.
Lowry WE; Broad Stem Cell Center, University of California Los Angeles, Los Angeles, California, United States of America.; Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America.; Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America.; Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Jan 04; Vol. 12 (1), pp. e0169237. Date of Electronic Publication: 2017 Jan 04 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs/*genetics
Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans Proteins/genetics ; Cell Line ; Gene Expression Regulation ; Humans ; Promoter Regions, Genetic/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Transcription, Genetic/genetics
Czasopismo naukowe
Tytuł:
Identification of Blood Let-7e-5p as a Biomarker for Ischemic Stroke.
Autorzy:
Huang S; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Lv Z; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Guo Y; Department of Neurology, People's Hospital of Shenzen, Guangdong, China.
Li L; Key Laboratory of Environment and Health, Ministry of Education and Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhang Y; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Zhou L; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Yang B; State Key Lab of Respiratory Disease, Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China.
Wu S; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Zhang Y; Department of Neurology, People's Hospital of Shenzen, Guangdong, China.
Xie C; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Li S; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Cheng J; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
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Źródło:
PloS one [PLoS One] 2016 Oct 24; Vol. 11 (10), pp. e0163951. Date of Electronic Publication: 2016 Oct 24 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers/*blood
Brain Ischemia/*genetics
MicroRNAs/*blood
Stroke/*genetics
Aged ; Female ; Humans ; Male ; Middle Aged ; ROC Curve ; U937 Cells
Czasopismo naukowe
Tytuł:
Adiponectin Upregulates MiR-133a in Cardiac Hypertrophy through AMPK Activation and Reduced ERK1/2 Phosphorylation.
Autorzy:
Li Y; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.; Central Laboratory, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
Cai X; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
Guan Y; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
Wang L; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
Wang S; School of Medicine, Shandong University, Jinan, China.
Li Y; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
Fu Y; School of Medicine, Shandong University, Jinan, China.
Gao X; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
Su G; Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
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Źródło:
PloS one [PLoS One] 2016 Feb 04; Vol. 11 (2), pp. e0148482. Date of Electronic Publication: 2016 Feb 04 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation*
AMP-Activated Protein Kinases/*metabolism
Adiponectin/*metabolism
Cardiomegaly/*genetics
Cardiomegaly/*metabolism
MicroRNAs/*genetics
Mitogen-Activated Protein Kinase 1/*metabolism
Mitogen-Activated Protein Kinase 3/*metabolism
Adiponectin/genetics ; Angiotensin II/adverse effects ; Animals ; Cardiomegaly/chemically induced ; Cardiomegaly/diagnosis ; Connective Tissue Growth Factor/genetics ; Connective Tissue Growth Factor/metabolism ; Disease Models, Animal ; Echocardiography/methods ; Gene Expression ; Genetic Vectors/genetics ; Lentivirus/genetics ; Male ; Myocytes, Cardiac/metabolism ; Phosphorylation ; Rats ; Receptors, Adiponectin/metabolism ; Signal Transduction ; Transduction, Genetic ; Up-Regulation
Czasopismo naukowe
Tytuł:
The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer.
Autorzy:
Jin Y; Department of Pathology, School of Basic Medical Science, Fudan University, Shanghai, China.; Department of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Liu Y; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhang J; Key Laboratory of Molecular Medicine, Ministry of Education, Institute of Medical Sciences, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, China.
Huang W; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Jiang H; Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Hou Y; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
Xu C; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhai C; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
Gao X; Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
Wang S; Department of Pathology, School of Basic Medical Science, Fudan University, Shanghai, China.
Wu Y; Department of Pathology, School of Basic Medical Science, Fudan University, Shanghai, China.
Zhu H; Department of Pathology, School of Basic Medical Science, Fudan University, Shanghai, China.; Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
Lu S; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2015 Dec 07; Vol. 10 (12), pp. e0144187. Date of Electronic Publication: 2015 Dec 07 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Adenocarcinoma/*metabolism
Carcinoma, Squamous Cell/*metabolism
Lung Neoplasms/*metabolism
MicroRNAs/*metabolism
Neoplasm Proteins/*biosynthesis
RNA, Neoplasm/*metabolism
Small Cell Lung Carcinoma/*metabolism
Adenocarcinoma/classification ; Adenocarcinoma/pathology ; Aged ; Carcinoma, Squamous Cell/classification ; Carcinoma, Squamous Cell/pathology ; Female ; Humans ; Lung Neoplasms/classification ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Small Cell Lung Carcinoma/classification ; Small Cell Lung Carcinoma/pathology
Czasopismo naukowe
Tytuł:
Cyclooxygenase-2, a Potential Therapeutic Target, Is Regulated by miR-101 in Esophageal Squamous Cell Carcinoma.
Autorzy:
Shao Y; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Li P; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Zhu ST; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Yue JP; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Ji XJ; Intensive Care Unit, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
He Z; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Ma D; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Wang L; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Wang YJ; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Zong Y; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Wu YD; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
Zhang ST; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, China.
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Źródło:
PloS one [PLoS One] 2015 Nov 10; Vol. 10 (11), pp. e0140642. Date of Electronic Publication: 2015 Nov 10 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Therapy*
Carcinoma, Squamous Cell/*enzymology
Cyclooxygenase 2/*biosynthesis
Esophageal Neoplasms/*enzymology
MicroRNAs/*genetics
Neoplasm Proteins/*biosynthesis
RNA, Neoplasm/*genetics
Animals ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/therapy ; Cell Line, Tumor ; Cell Movement ; Cyclooxygenase 2/genetics ; Down-Regulation ; Enzyme Induction/genetics ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/therapy ; Esophagus/chemistry ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Reporter ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/biosynthesis ; Molecular Targeted Therapy ; Neoplasm Invasiveness ; Neoplasm Proteins/genetics ; RNA, Neoplasm/biosynthesis ; Real-Time Polymerase Chain Reaction ; Transfection ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis.
Autorzy:
Lochhead RB; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Zachary JF; Department of Veterinary Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
Dalla Rosa L; Department of Microbiology and Parasitology, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil.
Ma Y; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Weis JH; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
O'Connell RM; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Weis JJ; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Aug 07; Vol. 10 (8), pp. e0135142. Date of Electronic Publication: 2015 Aug 07 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis/*metabolism
Interleukin-10/*metabolism
Lyme Disease/*metabolism
MicroRNAs/*metabolism
Myocarditis/*metabolism
Animals ; Arthritis/microbiology ; Bone Marrow Cells/cytology ; Borrelia burgdorferi ; Disease Models, Animal ; Female ; Gene Expression Regulation ; Genotype ; Immune System ; Immunity, Innate ; Lyme Disease/microbiology ; Macrophages/cytology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myocarditis/microbiology ; Phagocytosis ; Protein Binding ; Th1 Cells/cytology
Czasopismo naukowe
Tytuł:
Association of Altered Serum MicroRNAs with Perihematomal Edema after Acute Intracerebral Hemorrhage.
Autorzy:
Zhu Y; Department of Neurology, The First Hospital of China Medical University, Shenyang, China.
Wang JL; Department of Neurology, The First Hospital of China Medical University, Shenyang, China.
He ZY; Department of Neurology, The First Hospital of China Medical University, Shenyang, China.
Jin F; Department of Neurology, The First Hospital of China Medical University, Shenyang, China.
Tang L; Department of Neurology, The First Hospital of China Medical University, Shenyang, China.
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Źródło:
PloS one [PLoS One] 2015 Jul 24; Vol. 10 (7), pp. e0133783. Date of Electronic Publication: 2015 Jul 24 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Edema/*blood
Brain Edema/*etiology
Cerebral Hemorrhage/*complications
Hematoma/*complications
Hematoma/*etiology
MicroRNAs/*blood
MicroRNAs/*genetics
Brain Edema/diagnosis ; Case-Control Studies ; Cerebral Hemorrhage/diagnosis ; Female ; Gene Expression Profiling ; Hematoma/diagnosis ; Humans ; Male ; Middle Aged ; Prospective Studies ; RNA Interference ; RNA, Messenger/genetics ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł:
miR-150 Deficiency Protects against FAS-Induced Acute Liver Injury in Mice through Regulation of AKT.
Autorzy:
Chen W; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine,1430 Tulane Avenue SL-79, New Orleans, Louisiana, United States of America.
Han C; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine,1430 Tulane Avenue SL-79, New Orleans, Louisiana, United States of America.
Zhang J; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine,1430 Tulane Avenue SL-79, New Orleans, Louisiana, United States of America.
Song K; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine,1430 Tulane Avenue SL-79, New Orleans, Louisiana, United States of America.
Wang Y; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine,1430 Tulane Avenue SL-79, New Orleans, Louisiana, United States of America; Department of Gastroenterology and Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu T; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine,1430 Tulane Avenue SL-79, New Orleans, Louisiana, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Jul 21; Vol. 10 (7), pp. e0132734. Date of Electronic Publication: 2015 Jul 21 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Gene Expression Regulation, Enzymologic*
Chemical and Drug Induced Liver Injury/*metabolism
MicroRNAs/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
fas Receptor/*metabolism
Animals ; Apoptosis ; Caspase 3/metabolism ; Caspases/metabolism ; Computational Biology ; Enzyme Inhibitors/chemistry ; Galactosamine/chemistry ; Gene Deletion ; Glycogen Synthase Kinase 3/metabolism ; Glycogen Synthase Kinase 3 beta ; Hepatocytes/cytology ; Hepatocytes/metabolism ; Lipopolysaccharides/chemistry ; Liver/metabolism ; Liver/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Transaminases/blood
Czasopismo naukowe
Tytuł:
A Systematic Analysis on mRNA and MicroRNA Expression in Runting and Stunting Chickens.
Autorzy:
Zhang L; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China; Agricultural College, Guangdong Ocean University, Zhanjiang, 524088, P.R. China.
Li Y; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China; Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P.R. China.
Xie X; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Xu H; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Xu Z; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Ma J; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Li B; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Lin S; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Nie Q; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Luo Q; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
Zhang X; Guangdong Provincial Key Lab of Agro-animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, P.R. China.
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Źródło:
PloS one [PLoS One] 2015 May 26; Vol. 10 (5), pp. e0127342. Date of Electronic Publication: 2015 May 26 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chickens/*genetics
Growth Disorders/*genetics
MicroRNAs/*genetics
Poultry Diseases/*genetics
RNA, Messenger/*genetics
Transcriptome/*genetics
3' Untranslated Regions/genetics ; Animals ; Gene Expression Profiling/methods ; Liver/metabolism
Czasopismo naukowe

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