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Tytuł:
Circ-CHFR modulates the proliferation, migration, and invasion of ox-LDL-induced human aorta vascular smooth muscle cells through the miR-214-3p/PAPPA axis.
Autorzy:
Lu Q; Third Department of Cardiology, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi City, Xinjiang, China.
Li Y; Department of Emergency, First Teaching Hospital of Tianjin University of TCM, Tianjin, China.
Lou J; Department of Cardiology, Yuquan Hospital of Tsinghua University, Beijing, China.
Li P; Third Department of Cardiology, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi City, Xinjiang, China.
Gu Y; Department of Cardiology, Nanjing Jiangbei People's Hospital Affiliated to Nantong University, Nanjing City, Jiangsu Province, China.
Wang X; Department of Cardiology, Yijishan Hospital of Wan Nan Medical College, Wuhu City, Anhui Province, China.
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Źródło:
Clinical hemorheology and microcirculation [Clin Hemorheol Microcirc] 2022; Vol. 80 (4), pp. 399-412.
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/genetics
Atherosclerosis*/pathology
Cell Movement*/physiology
Cell Proliferation*/physiology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Muscle, Smooth, Vascular*/metabolism
Pregnancy-Associated Plasma Protein-A*/metabolism
RNA, Circular*/genetics
Aorta/metabolism ; Aorta/pathology ; Cell Cycle Proteins ; Cells, Cultured ; Humans ; Lipoproteins, LDL/metabolism ; Lipoproteins, LDL/pharmacology ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Poly-ADP-Ribose Binding Proteins/metabolism ; Signal Transduction ; Ubiquitin-Protein Ligases
Czasopismo naukowe
Tytuł:
Knockdown of MIR9‑3HG inhibits proliferation and promotes apoptosis of cervical cancer cells by miR‑498 via EP300.
Autorzy:
Li F; Gynaecology Department, Jiangxi Maternal and Child Health Hospital, Nanchang, Jiangxi 330006, P.R. China.
Liang Y; Gynecology Department, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330004, P.R. China.
Ying P; Department of Gynecology and Obstetrics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310006, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 Nov; Vol. 24 (5). Date of Electronic Publication: 2021 Sep 01.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*genetics
Cell Proliferation/*genetics
E1A-Associated p300 Protein/*metabolism
MicroRNAs/*metabolism
Uterine Cervical Neoplasms/*genetics
Animals ; Cell Line, Tumor ; Cervix Uteri/pathology ; Female ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Mice ; MicroRNAs/genetics ; Transcriptome ; Uterine Cervical Neoplasms/pathology
Czasopismo naukowe
Tytuł:
Interference with lncRNA NEAT1 promotes the proliferation, migration, and invasion of trophoblasts by upregulating miR-411-5p and inhibiting PTEN expression.
Autorzy:
Fan X; Department of Obstetrics and Gynecology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Lou J; Department of Obstetrics and Gynecology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Zheng X; Department of Obstetrics and Gynecology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Wang Y; Department of Obstetrics and Gynecology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Wang J; Department of Obstetrics and Gynecology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Luo M; Department of Obstetrics and Gynecology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Hu M; Department of Obstetrics and Gynecology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
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Źródło:
Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2021 Jun; Vol. 43 (3), pp. 334-342. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji:
Journal Article; Video-Audio Media
MeSH Terms:
Cell Movement*
Cell Proliferation*
Gene Expression Regulation, Developmental*
Up-Regulation*
MicroRNAs/*biosynthesis
PTEN Phosphohydrolase/*biosynthesis
RNA, Long Noncoding/*metabolism
Trophoblasts/*metabolism
Cell Line ; Female ; Humans ; Pregnancy ; RNA, Long Noncoding/genetics
Czasopismo naukowe
Tytuł:
lncRNA MRUL Suppressed Non-Small Cell Lung Cancer Cells Proliferation and Invasion by Targeting miR-17-5p/SRSF2 Axis.
Autorzy:
Chen Y; Department of Radiation Oncology, Zhejiang Key Laboratory of Radiation Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital); Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, 1 Banshandong Road, 310022 hangzhou, Zhejiang, China.
Shen T; Department of Radiation Oncology, Jiaotong University School of Medicine, 197 Ruijin Second Road, 200000 Shanghai, China.
Ding X; Department of Respiratory Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310000 Zhejiang, China.
Ma C; Department of Endocrinology and Metabolism, Zhejiang Greentown Cardiovascular Hospital, 409 Gudun Road, 310000 Zhejiang, China.
Cheng L; Department of Radiation Oncology, Zhejiang Key Laboratory of Radiation Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital); Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, 1 Banshandong Road, 310022 hangzhou, Zhejiang, China.
Sheng L; Department of Radiation Oncology, Zhejiang Key Laboratory of Radiation Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital); Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, 1 Banshandong Road, 310022 hangzhou, Zhejiang, China.
Du X; Department of Radiation Oncology, Zhejiang Key Laboratory of Radiation Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital); Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, 1 Banshandong Road, 310022 hangzhou, Zhejiang, China.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Oct 07; Vol. 2020, pp. 9567846. Date of Electronic Publication: 2020 Oct 07 (Print Publication: 2020).
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Carcinoma, Non-Small-Cell Lung/*genetics
Cell Proliferation/*genetics
Lung Neoplasms/*genetics
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
Serine-Arginine Splicing Factors/*genetics
A549 Cells ; Carcinogenesis/genetics ; Carcinogenesis/pathology ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Lung Neoplasms/pathology ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/pathology ; Prognosis
Czasopismo naukowe
Tytuł:
Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a.
Autorzy:
Cui J; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Li H; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Wang Y; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Tian T; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Liu C; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Wang Y; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Sun S; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Feng B; Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
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Źródło:
BioFactors (Oxford, England) [Biofactors] 2020 Sep; Vol. 46 (5), pp. 821-830. Date of Electronic Publication: 2020 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Proliferation/*drug effects
Flavones/*pharmacology
MicroRNAs/*genetics
Pancreatic Neoplasms/*drug therapy
Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/pathology
Czasopismo naukowe
Tytuł:
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Autorzy:
Ying Y; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Li J; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xie H; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Yan H; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Jin K; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
He L; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Ma X; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Wu J; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xu X; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Fang J; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Wang X; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Zheng X; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Liu B; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xie L; Department of Urology, School of Medicine, First Affiliated Hospital of Zhejiang University, Hangzhou, China.
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Źródło:
Cell proliferation [Cell Prolif] 2020 Feb; Vol. 53 (2), pp. e12751. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Movement/*genetics
Cell Proliferation/*genetics
Cyclin D1/*genetics
DNA (Cytosine-5-)-Methyltransferases/*genetics
MicroRNAs/*genetics
Nuclear Proteins/*genetics
Urinary Bladder Neoplasms/*genetics
Animals ; Cell Line ; Cell Line, Tumor ; CpG Islands/genetics ; DNA Methylation/genetics ; Down-Regulation/genetics ; Gene Expression Regulation, Neoplastic/genetics ; HEK293 Cells ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Urinary Bladder Neoplasms/pathology ; DNA Methyltransferase 3B
Czasopismo naukowe
Tytuł:
Long non‑coding RNA NORAD promotes cell proliferation and glycolysis in non‑small cell lung cancer by acting as a sponge for miR‑136‑5p.
Autorzy:
Gao W; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Weng T; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Wang L; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Shi B; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Meng W; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Wang X; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Wu Y; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Jin L; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
Fei L; Department of Respiratory Medicine, Suqian People's Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu 223800, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2019 Jun; Vol. 19 (6), pp. 5397-5405. Date of Electronic Publication: 2019 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Proliferation*
MicroRNAs/*metabolism
RNA, Long Noncoding/*metabolism
Antagomirs/metabolism ; Base Sequence ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; E2F1 Transcription Factor/genetics ; E2F1 Transcription Factor/metabolism ; Glycolysis ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/genetics ; RNA Interference ; RNA, Long Noncoding/antagonists & inhibitors ; RNA, Long Noncoding/genetics ; RNA, Small Interfering/metabolism ; Sequence Alignment
Czasopismo naukowe
Tytuł:
MiR-145-targeted HBXIP modulates human breast cancer cell proliferation.
Autorzy:
Jiang Y; Department of Gastrointestinal Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Wang D; Department of Breast Surgery, The Second Hospital of Jilin University, Changchun, China.
Ren H; Department of General Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Shi Y; Department of Breast-Thyroid Surgery, The Second Hospital of Jilin University, Changchun, China.
Gao Y; Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China.
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Źródło:
Thoracic cancer [Thorac Cancer] 2019 Jan; Vol. 10 (1), pp. 71-77. Date of Electronic Publication: 2018 Oct 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptor Proteins, Signal Transducing/*genetics
Breast Neoplasms/*genetics
Cell Proliferation/*genetics
MicroRNAs/*genetics
Adult ; Aged ; Breast Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; MCF-7 Cells ; Middle Aged ; Promoter Regions, Genetic ; Signal Transduction
Czasopismo naukowe
Tytuł:
Knockdown of lncRNA CCAT2 inhibits endometrial cancer cells growth and metastasis via sponging miR-216b.
Autorzy:
Xie P; The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong, China.; Department of Gynecology, Jining No.1 People's Hospital, Jining 272011, Shandong, China.
Cao H; Department of Pathology, Jining No.1 People's Hospital, Jining 272011, Shandong, China.
Li Y; Department of Gynecology and Obstetrics, Shanxian Central Hospital, Heze 274300, Shandong, China.
Wang J; Department of Gynecology and Obstetrics, Shanxian Central Hospital, Heze 274300, Shandong, China.
Cui Z; Department of Gynecology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong, China.
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Źródło:
Cancer biomarkers : section A of Disease markers [Cancer Biomark] 2017 Dec 12; Vol. 21 (1), pp. 123-133.
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Gene Expression Regulation, Neoplastic*
RNA Interference*
Cell Proliferation/*genetics
Endometrial Neoplasms/*genetics
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
Apoptosis/genetics ; Cell Line, Tumor ; Endometrial Neoplasms/metabolism ; Endometrial Neoplasms/pathology ; Female ; Humans ; Middle Aged ; Neoplasm Metastasis ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
MicroRNA‑497 inhibits cellular proliferation, migration and invasion of papillary thyroid cancer by directly targeting AKT3.
Autorzy:
Zhuang J; Department of Nuclear Medicine, Tenth People's Hospital of Tongji University, Shanghai 200072, P.R. China.
Ye Y; Department of Nuclear Medicine, The Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200137, P.R. China.
Wang G; Department of Nuclear Medicine, The Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200137, P.R. China.
Ni J; Department of Nuclear Medicine, The Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200137, P.R. China.
He S; Department of Nuclear Medicine, The Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200137, P.R. China.
Hu C; Department of Nuclear Medicine, The Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200137, P.R. China.
Xia W; Department of Nuclear Medicine, The Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200137, P.R. China.
Lv Z; Department of Nuclear Medicine, Tenth People's Hospital of Tongji University, Shanghai 200072, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Nov; Vol. 16 (5), pp. 5815-5822. Date of Electronic Publication: 2017 Aug 24.
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Carcinoma, Papillary/*genetics
Cell Proliferation/*genetics
MicroRNAs/*genetics
Proto-Oncogene Proteins c-akt/*genetics
Thyroid Neoplasms/*genetics
Adult ; Aged ; Apoptosis/genetics ; Carcinoma, Papillary/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/pathology ; RNA Interference ; Signal Transduction ; Thyroid Cancer, Papillary ; Thyroid Neoplasms/pathology
Czasopismo naukowe
Tytuł:
Effects of miR-145 on the inhibition of chondrocyte proliferation and fibrosis by targeting TNFRSF11B in human osteoarthritis.
Autorzy:
Wang GD; Qingdao University, Qingdao, Shandong 266000, P.R. China.
Zhao XW; Department of Orthopaedics, The Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
Zhang YG; Department of Orthopaedics, The Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
Kong Y; Department of Orthopaedics, The Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
Niu SS; Department of Orthopaedics, The Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
Ma LF; Department of Orthopaedics, The Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
Zhang YM; Department of Orthopaedics, The Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Jan; Vol. 15 (1), pp. 75-80. Date of Electronic Publication: 2016 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Proliferation*
Gene Expression Regulation*
Chondrocytes/*pathology
MicroRNAs/*genetics
Osteoarthritis, Knee/*genetics
Osteoarthritis, Knee/*pathology
Osteoprotegerin/*genetics
Cartilage, Articular/metabolism ; Cartilage, Articular/pathology ; Cell Line ; Fibrosis ; Humans
Czasopismo naukowe
Tytuł:
TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21.
Autorzy:
Liu Y; Department of Plastic and Aesthetic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, People's Republic of China.
Li Y; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, People's Republic of China.
Li N; Department of Plastic and Aesthetic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, People's Republic of China.
Teng W; Department of Plastic and Aesthetic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, People's Republic of China.
Wang M; Department of Plastic and Aesthetic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, People's Republic of China.
Zhang Y; Department of Plastic and Aesthetic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, People's Republic of China.
Xiao Z; Department of Plastic and Aesthetic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, People's Republic of China.
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Źródło:
Scientific reports [Sci Rep] 2016 Aug 24; Vol. 6, pp. 32231. Date of Electronic Publication: 2016 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Proliferation/*drug effects
Cell Transdifferentiation/*drug effects
Fibroblasts/*metabolism
Keloid/*metabolism
MicroRNAs/*biosynthesis
Transforming Growth Factor beta1/*pharmacology
Up-Regulation/*drug effects
Cells, Cultured ; Fibroblasts/pathology ; Humans ; Keloid/pathology ; Matrix Metalloproteinase 2/biosynthesis ; Matrix Metalloproteinase 9/biosynthesis ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł:
MiR-124 exerts tumor suppressive functions on the cell proliferation, motility and angiogenesis of bladder cancer by fine-tuning UHRF1.
Autorzy:
Wang X; Department of Urology, China-Japan Union Hospital of Jilin University, Changchun, China.
Wu Q; Tianjin Neurosurgery Institute, Tianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin Huanhu Hospital, China.
Xu B; The Graduate School, Tianjin Medical University, China.
Wang P; The Graduate School, Tianjin Medical University, China.
Fan W; Tianjin Neurosurgery Institute, Tianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin Huanhu Hospital, China.
Cai Y; Tianjin Neurosurgery Institute, Tianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin Huanhu Hospital, China.
Gu X; Department of Urology, China-Japan Union Hospital of Jilin University, Changchun, China.
Meng F; Department of Urology, China-Japan Union Hospital of Jilin University, Changchun, China.
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Źródło:
The FEBS journal [FEBS J] 2015 Nov; Vol. 282 (22), pp. 4376-88. Date of Electronic Publication: 2015 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Movement*
Cell Proliferation*
CCAAT-Enhancer-Binding Proteins/*physiology
MicroRNAs/*physiology
Urinary Bladder Neoplasms/*pathology
Animals ; CCAAT-Enhancer-Binding Proteins/genetics ; Cell Line, Tumor ; DNA Methylation ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Neoplasm Invasiveness ; Neovascularization, Pathologic ; Ubiquitin-Protein Ligases ; Urinary Bladder Neoplasms/blood supply ; Urinary Bladder Neoplasms/prevention & control
Czasopismo naukowe
Tytuł:
MicroRNA-148a inhibits the proliferation and promotes the paclitaxel-induced apoptosis of ovarian cancer cells by targeting PDIA3.
Autorzy:
Zhao S; Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
Wen Z; Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
Liu S; Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
Liu Y; Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
Li X; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
Ge Y; Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
Li S; Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2015 Sep; Vol. 12 (3), pp. 3923-3929. Date of Electronic Publication: 2015 May 25.
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Cell Proliferation*
Antineoplastic Agents, Phytogenic/*pharmacology
MicroRNAs/*genetics
Ovarian Neoplasms/*metabolism
Paclitaxel/*pharmacology
Protein Disulfide-Isomerases/*genetics
3' Untranslated Regions ; Apoptosis ; Base Sequence ; Binding Sites ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/pathology ; Protein Disulfide-Isomerases/metabolism ; RNA Interference
Czasopismo naukowe
Tytuł:
A critical role of mir-199a in the cell biological behaviors of colorectal cancer.
Autorzy:
Ye H; Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, Guangdong, 524023, China. yehua_.
Pang L; Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, Guangdong, 524023, China. pangliping.
Wu Q; Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, Guangdong, 524023, China. wu_qiong_.
Zhu Y; Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, Guangdong, 524023, China. drzheng_.
Guo C; Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, Guangdong, 524023, China. .
Deng Y; Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, Guangdong, 524023, China. .
Zheng X; Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, Guangdong, 524023, China. zheng_.
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Źródło:
Diagnostic pathology [Diagn Pathol] 2015 Jun 12; Vol. 10, pp. 65. Date of Electronic Publication: 2015 Jun 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*genetics
Cell Proliferation/*genetics
Colorectal Neoplasms/*genetics
MicroRNAs/*biosynthesis
Neoplasm Invasiveness/*genetics
Blotting, Western ; Cell Movement/genetics ; Colorectal Neoplasms/pathology ; Down-Regulation ; Female ; Flow Cytometry ; Humans ; Male ; Middle Aged ; Real-Time Polymerase Chain Reaction ; Transfection
Czasopismo naukowe
Tytuł:
Reexpression of Let-7g microRNA inhibits the proliferation and migration via K-Ras/HMGA2/snail axis in hepatocellular carcinoma.
Autorzy:
Chen KJ; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Hou Y; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Wang K; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Li J; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Xia Y; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Yang XY; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Lv G; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Xing XL; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
Shen F; Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, 225 Changhai Road, Shanghai 200438, China.
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Źródło:
BioMed research international [Biomed Res Int] 2014; Vol. 2014, pp. 742417. Date of Electronic Publication: 2014 Mar 04.
Typ publikacji:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Movement*
Cell Proliferation*
Gene Expression Regulation, Neoplastic*
Carcinoma, Hepatocellular/*metabolism
HMGA2 Protein/*metabolism
Liver Neoplasms/*metabolism
MicroRNAs/*biosynthesis
Proto-Oncogene Proteins/*metabolism
RNA, Neoplasm/*biosynthesis
Transcription Factors/*metabolism
ras Proteins/*metabolism
Animals ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Female ; HMGA2 Protein/genetics ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins p21(ras) ; RNA, Neoplasm/genetics ; Snail Family Transcription Factors ; Transcription Factors/genetics ; ras Proteins/genetics
Czasopismo naukowe
Tytuł:
MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma.
Autorzy:
Liu N
Jiang N
Guo R
Jiang W
He QM
Xu YF
Li YQ
Tang LL
Mao YP
Sun Y
Ma J; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou People's Republic of China. .
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Źródło:
Molecular cancer [Mol Cancer] 2013 Oct 20; Vol. 12 (1), pp. 123. Date of Electronic Publication: 2013 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Proliferation*
Carcinoma/*metabolism
Intramolecular Oxidoreductases/*genetics
Macrophage Migration-Inhibitory Factors/*genetics
MicroRNAs/*genetics
Nasopharyngeal Neoplasms/*metabolism
Adult ; Animals ; Base Sequence ; Carcinoma/mortality ; Carcinoma/pathology ; Cell Line, Tumor ; Cell Movement ; Cell Survival ; Disease-Free Survival ; Female ; Gene Expression ; Gene Expression Regulation, Neoplastic ; Guanine Nucleotide Exchange Factors/genetics ; Guanine Nucleotide Exchange Factors/metabolism ; Humans ; Intramolecular Oxidoreductases/metabolism ; Kaplan-Meier Estimate ; Macrophage Migration-Inhibitory Factors/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms/mortality ; Nasopharyngeal Neoplasms/pathology ; Neoplasm Invasiveness ; Neoplasm Transplantation ; Proportional Hazards Models ; RNA Interference ; T-Lymphoma Invasion and Metastasis-inducing Protein 1 ; Tumor Burden
Czasopismo naukowe
Tytuł:
MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreatic cancer through targeting STAT3.
Autorzy:
Zhao G; Pancreatic Disease Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang JG
Shi Y
Qin Q
Liu Y
Wang B
Tian K
Deng SC
Li X
Zhu S
Gong Q
Niu Y
Wang CY
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Źródło:
PloS one [PLoS One] 2013 Sep 10; Vol. 8 (9), pp. e73803. Date of Electronic Publication: 2013 Sep 10 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Proliferation*
Biomarkers, Tumor/*genetics
MicroRNAs/*genetics
Pancreatic Neoplasms/*genetics
STAT3 Transcription Factor/*genetics
3' Untranslated Regions/genetics ; Animals ; Apoptosis/genetics ; Blotting, Western ; Cell Cycle Checkpoints/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Kaplan-Meier Estimate ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Neoplasm Invasiveness ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Prognosis ; Reverse Transcriptase Polymerase Chain Reaction ; STAT3 Transcription Factor/metabolism ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł:
KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways.
Autorzy:
Moody R; Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America ; Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Zhu Y; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Huang Y; Department of Electrical and Computer Engineering, University of Texas at San Antonio, San Antonio, Texas, United States of America.
Cui X; Department of Electrical and Computer Engineering, University of Texas at San Antonio, San Antonio, Texas, United States of America.
Jones T; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Bedolla R; Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Lei X; Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Bai Z; Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Gao SJ; Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America ; Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America ; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (12), pp. e1003857. Date of Electronic Publication: 2013 Dec 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Proliferation*
Carcinogenesis/*genetics
Cell Transformation, Viral/*genetics
Herpesvirus 8, Human/*genetics
MicroRNAs/*physiology
Animals ; Cell Survival/genetics ; Cells, Cultured ; Gene Regulatory Networks ; Gene Targeting ; Humans ; Microarray Analysis ; Rats ; Signal Transduction/genetics ; Transcriptome
Czasopismo naukowe
Tytuł:
MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer.
Autorzy:
Wang Y; State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Disease, Fourth Military Medical University, Xi'an, Shaanxi, China.
Zheng X
Zhang Z
Zhou J
Zhao G
Yang J
Xia L
Wang R
Cai X
Hu H
Zhu C
Nie Y
Wu K
Zhang D
Fan D
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (10), pp. e41693. Date of Electronic Publication: 2012 Oct 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Proliferation*
Cell Cycle Checkpoints/*genetics
MicroRNAs/*genetics
Repressor Proteins/*genetics
Stomach Neoplasms/*genetics
3' Untranslated Regions/genetics ; Base Sequence ; Binding Sites/genetics ; Blotting, Western ; Cell Line ; Cell Line, Tumor ; Down-Regulation ; G1 Phase/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; MicroRNAs/metabolism ; Mutation ; Repressor Proteins/metabolism ; Resting Phase, Cell Cycle/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/pathology
Czasopismo naukowe

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