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Wyświetlanie 1-13 z 13
Tytuł :
Fecundity among women with polycystic ovary syndrome (PCOS)-a population-based study.
Autorzy :
Persson S; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.; Department of Obstetrics and Gynecology, Sundsvall County Hospital, Sundsvall, Sweden.
Elenis E; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Turkmen S; Department of Clinical Sciences, Obstetrics and Gynecology, Sundsvalls Research Unit, Umeå University, Umeå, Sweden.; Department of Obstetrics and Gynecology, Sundsvall County Hospital, Sundsvall, Sweden.
Kramer MS; Departments of Epidemiology, Biostatistics & Occupational Health and of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec, Canada.; Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, Singapore.
Yong EL; Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, Singapore.
Sundström-Poromaa I; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
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Źródło :
Human reproduction (Oxford, England) [Hum Reprod] 2019 Oct 02; Vol. 34 (10), pp. 2052-2060.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fertility/*physiology
Infertility, Female/*epidemiology
Parity/*physiology
Parturition/*physiology
Polycystic Ovary Syndrome/*physiopathology
Adult ; Age Factors ; Case-Control Studies ; Educational Status ; Family Characteristics ; Female ; Follow-Up Studies ; Humans ; Infertility, Female/etiology ; Maternal Age ; Polycystic Ovary Syndrome/complications ; Pregnancy ; Registries/statistics & numerical data ; Sweden/epidemiology ; Time Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Cohort Profile: The Integrated Women's Health Programme (IWHP): a study of key health issues of midlife Singaporean women.
Autorzy :
Thu WPP; Department of Obstetrics and Gynaecology, National University of Singapore (NUS), Republic of Singapore.
Logan SJS; Department of Obstetrics and Gynaecology, National University of Singapore (NUS), Republic of Singapore.
Lim CW; Department of Obstetrics and Gynaecology, National University of Singapore (NUS), Republic of Singapore.
Wang YL; Department of Obstetrics and Gynaecology, National University of Singapore (NUS), Republic of Singapore.
Cauley JA; University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, USA.
Yong EL; Department of Obstetrics and Gynaecology, National University of Singapore (NUS), Republic of Singapore.
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Źródło :
International journal of epidemiology [Int J Epidemiol] 2018 Apr 01; Vol. 47 (2), pp. 389-390f.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Women's Health*
Ethnic Groups/*statistics & numerical data
Menopause/*physiology
Menopause/*psychology
Aged ; Demography ; Female ; Gynecology ; Health Promotion ; Humans ; Middle Aged ; Prospective Studies ; Self Report ; Singapore
Czasopismo naukowe
Tytuł :
A Dietary Medium-Chain Fatty Acid, Decanoic Acid, Inhibits Recruitment of Nur77 to the HSD3B2 Promoter In Vitro and Reverses Endocrine and Metabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome.
Autorzy :
Lee BH; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.
Indran IR; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.
Tan HM; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.
Li Y; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.
Zhang Z; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.
Li J; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.
Yong EL; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.
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Źródło :
Endocrinology [Endocrinology] 2016 Jan; Vol. 157 (1), pp. 382-94. Date of Electronic Publication: 2015 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Promoter Regions, Genetic*
Decanoic Acids/*therapeutic use
Dietary Fats/*therapeutic use
Nuclear Receptor Subfamily 4, Group A, Member 1/*antagonists & inhibitors
Polycystic Ovary Syndrome/*diet therapy
Progesterone Reductase/*antagonists & inhibitors
Adrenal Cortex/enzymology ; Adrenal Cortex/metabolism ; Adrenal Glands/enzymology ; Adrenal Glands/metabolism ; Androgens/analysis ; Androgens/chemistry ; Androgens/metabolism ; Animals ; Cell Line ; Cyclic AMP/antagonists & inhibitors ; Cyclic AMP/metabolism ; Decanoic Acids/metabolism ; Dietary Fats/metabolism ; Enzyme Repression ; Female ; Humans ; Hyperandrogenism/etiology ; Hyperandrogenism/prevention & control ; Insulin Resistance ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Nuclear Receptor Subfamily 4, Group A, Member 1/metabolism ; Ovary/enzymology ; Ovary/metabolism ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/pathology ; Polycystic Ovary Syndrome/physiopathology ; Progesterone Reductase/genetics ; Progesterone Reductase/metabolism ; Random Allocation ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Prognostic value of Y deletion analysis: How reliable is the outcome of Y deletion analysis in providing a sound prognosis?
Autorzy :
Liow SL; Department of Obstetrics and Gynaecology, National University Hospital, Lower Kent Ridge Road, Singapore 119074.
Yong EL
Ng SC
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Źródło :
Human reproduction (Oxford, England) [Hum Reprod] 2001 Jan; Vol. 16 (1), pp. 9-12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Chromosome Deletion*
Infertility, Male/*genetics
Y Chromosome/*genetics
Female ; Genetic Counseling ; Genetic Techniques ; Humans ; Male ; Oligospermia/genetics ; Polymerase Chain Reaction ; Pregnancy ; Prognosis ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Androgen receptor gene CAG trinucleotide repeats in anovulatory infertility and polycystic ovaries.
Autorzy :
Mifsud A; Department of Obstetrics and Gynaecology, National University of Singapore, Republic of Singapore.
Ramirez S
Yong EL
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2000 Sep; Vol. 85 (9), pp. 3484-8.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Anovulation/*genetics
Infertility, Female/*genetics
Polycystic Ovary Syndrome/*genetics
Receptors, Androgen/*biosynthesis
Trinucleotide Repeats/*genetics
Adult ; Alleles ; Anovulation/metabolism ; Asian Continental Ancestry Group ; Case-Control Studies ; DNA/chemistry ; DNA/genetics ; European Continental Ancestry Group ; Female ; Gonadal Steroid Hormones/blood ; Humans ; Infertility, Female/metabolism ; Polycystic Ovary Syndrome/metabolism ; Receptors, Androgen/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Testosterone/blood
Czasopismo naukowe
Tytuł :
Azoospermia associated with a mutation in the ligand-binding domain of an androgen receptor displaying normal ligand binding, but defective trans-activation.
Autorzy :
Wang Q; Department of Obstetrics and Gynecology, National University of Singapore, Republic of Singapore.
Ghadessy FJ
Trounson A
de Kretser D
McLachlan R
Ng SC
Yong EL
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 1998 Dec; Vol. 83 (12), pp. 4303-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Germ-Line Mutation/*genetics
Oligospermia/*genetics
Receptors, Androgen/*genetics
Receptors, Androgen/*metabolism
Transcriptional Activation/*genetics
Adult ; Alleles ; Amino Acid Substitution/genetics ; Androgens/pharmacology ; Cell Line ; Humans ; Ligands ; Male ; Receptors, Androgen/drug effects
Czasopismo naukowe
Tytuł :
Long polyglutamine tracts in the androgen receptor are associated with reduced trans-activation, impaired sperm production, and male infertility.
Autorzy :
Tut TG; Department of Obstetrics and Gynecology, National University of Singapore, Republic of Singapore.
Ghadessy FJ
Trifiro MA
Pinsky L
Yong EL
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 1997 Nov; Vol. 82 (11), pp. 3777-82.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcriptional Activation*
Infertility, Male/*genetics
Peptides/*genetics
Receptors, Androgen/*genetics
Spermatogenesis/*genetics
Blotting, Western ; DNA/blood ; Electrophoresis, Polyacrylamide Gel ; Follicle Stimulating Hormone/blood ; Humans ; Luteinizing Hormone/blood ; Male ; Peptides/chemistry ; Point Mutation ; Polymerase Chain Reaction ; Polymorphism, Single-Stranded Conformational ; Receptors, Androgen/chemistry ; Receptors, Androgen/physiology ; Repetitive Sequences, Nucleic Acid ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Induction of spermatogenesis in isolated hypogonadotrophic hypogonadism with gonadotrophins and early intervention with intracytoplasmic sperm injection.
Autorzy :
Yong EL; Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
Lee KO
Ng SC
Ratnam SS
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Źródło :
Human reproduction (Oxford, England) [Hum Reprod] 1997 Jun; Vol. 12 (6), pp. 1230-2.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Chorionic Gonadotropin/*administration & dosage
Fertilization in Vitro/*methods
Hypogonadism/*drug therapy
Hypogonadism/*therapy
Infertility, Male/*drug therapy
Infertility, Male/*therapy
Menotropins/*administration & dosage
Spermatogenesis/*drug effects
Adult ; Cytoplasm ; Female ; Humans ; Hypogonadism/physiopathology ; Infertility, Male/physiopathology ; Male ; Microinjections ; Pregnancy ; Sperm Count ; Spermatozoa ; Testis/drug effects ; Testis/growth & development ; Testis/pathology
Czasopismo naukowe
Tytuł :
Intracytoplasmic sperm injection--is there a need for an animal model, especially in assessing the genetic risks involved?
Autorzy :
Ng SC; Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
Liow SL
Ahmadi A
Yong EL
Bongso A
Ratnam SS
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Źródło :
Human reproduction (Oxford, England) [Hum Reprod] 1995 Oct; Vol. 10 (10), pp. 2523-5.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cytoplasm*
Disease Models, Animal*
Microinjections*
Fertilization in Vitro/*methods
Infertility, Male/*genetics
Animals ; Female ; Humans ; Infertility, Male/therapy ; Male ; Risk Factors
Czasopismo naukowe
Tytuł :
Hormonal regulation of the growth and steroidogenic function of human granulosa cells.
Autorzy :
Yong EL; Department of Obstetrics and Gynaecology, University of Edinburgh Center for Reproductive Biology, Scotland.
Baird DT
Yates R
Reichert LE Jr
Hillier SG
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 1992 Apr; Vol. 74 (4), pp. 842-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Follicle Stimulating Hormone/*pharmacology
Granulosa Cells/*physiology
Growth/*drug effects
Luteinizing Hormone/*pharmacology
Adult ; Aromatase/metabolism ; Cell Differentiation/drug effects ; Cell Division/drug effects ; Cells, Cultured ; DNA/metabolism ; Dose-Response Relationship, Drug ; Drug Interactions ; Female ; Granulosa Cells/cytology ; Granulosa Cells/metabolism ; Humans ; Insulin-Like Growth Factor I/pharmacology ; Middle Aged ; Progesterone/metabolism ; Thymidine/metabolism ; Tritium
Czasopismo naukowe
Tytuł :
Effect of cyclofenil on hormonal dynamics, follicular development and cervical mucus in normal and oligomenorrhoeic women.
Autorzy :
Yong EL; Department of Obstetrics and Gynaecology, University of Edinburgh, UK.
Glasier A
Hillier H
Ledger W
Caird L
Beattie G
Sweeting V
Thong J
Baird DT
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Źródło :
Human reproduction (Oxford, England) [Hum Reprod] 1992 Jan; Vol. 7 (1), pp. 39-43.
Typ publikacji :
Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclofenil/*therapeutic use
Follicle Stimulating Hormone/*blood
Infertility, Female/*drug therapy
Luteinizing Hormone/*blood
Oligomenorrhea/*drug therapy
Ovarian Follicle/*drug effects
Adult ; Cervix Mucus/chemistry ; Double-Blind Method ; Drug Evaluation ; Estrone/urine ; Female ; Humans ; Infertility, Female/blood ; Oligomenorrhea/blood ; Oligomenorrhea/urine ; Ovarian Follicle/diagnostic imaging ; Ovulation Induction ; Pregnanediol/urine ; Ultrasonography
Czasopismo naukowe
Tytuł :
Effect of recombinant activin on androgen synthesis in cultured human thecal cells.
Autorzy :
Hillier SG; Department of Obstetrics and Gynecology, University of Edinburgh, Scotland, United Kingdom.
Yong EL
Illingworth PJ
Baird DT
Schwall RH
Mason AJ
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 1991 Jun; Vol. 72 (6), pp. 1206-11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Androgens/*biosynthesis
Inhibins/*pharmacology
Theca Cells/*metabolism
Activins ; Adult ; Androstenedione/antagonists & inhibitors ; Androstenedione/biosynthesis ; Cells, Cultured ; Female ; Humans ; Insulin-Like Growth Factor I/pharmacology ; Luteinizing Hormone/pharmacology ; Recombinant Proteins ; Steroids/biosynthesis ; Thymidine/pharmacokinetics
Czasopismo naukowe
Tytuł :
Cytogenetic analysis of unfertilized human oocytes.
Autorzy :
Angell RR; Department of Obstetrics and Gynaecology, University of Edinburgh, UK.
Ledger W
Yong EL
Harkness L
Baird DT
Pokaż więcej
Źródło :
Human reproduction (Oxford, England) [Hum Reprod] 1991 Apr; Vol. 6 (4), pp. 568-73.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Meiosis*
Oocytes/*ultrastructure
Cells, Cultured ; Chromosome Aberrations ; Fertilization in Vitro ; Humans ; In Vitro Techniques ; Karyotyping ; Trisomy
Czasopismo naukowe
    Wyświetlanie 1-13 z 13

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