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Wyświetlanie 1-20 z 73
Tytuł:
One Week of CDAHFD Induces Steatohepatitis and Mitochondrial Dysfunction with Oxidative Stress in Liver.
Autorzy:
Sugasawa T; Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
Ono S; Master's Program in Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
Yonamine M; Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
Fujita SI; Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
Matsumoto Y; Research and Development Section, Anicom Specialty Medical Institute Inc., 2-6-3 Chojamachi 5F, Yokohamashi-Nakaku 231-0033, Kanagawa, Japan.
Aoki K; Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.; Japan Society for the Promotion of Science, Kojimachi Business Center Building, Kojimachi, Chiyoda-ku, Tokyo 102-0083, Japan.
Nakano T; Master's Program in Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
Tamai S; Doctoral Program in Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
Yoshida Y; Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.; Department of Medical Technology, Faculty of Health Sciences, Tsukuba International University, 6-20-1 Manabe, Tsuchiura 300-0051, Ibaraki, Japan.
Kawakami Y; Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
Takekoshi K; Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 29; Vol. 22 (11). Date of Electronic Publication: 2021 May 29.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*
Choline Deficiency/*complications
Diet, High-Fat/*adverse effects
Mitochondria/*drug effects
Mitochondria/*metabolism
Non-alcoholic Fatty Liver Disease/*etiology
Non-alcoholic Fatty Liver Disease/*metabolism
Animals ; Biomarkers ; Disease Models, Animal ; Disease Susceptibility ; Gluconeogenesis ; Inflammation Mediators/metabolism ; Lipid Droplets/metabolism ; Lipid Metabolism ; Lipogenesis ; Liver Cirrhosis/etiology ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Mice ; Non-alcoholic Fatty Liver Disease/pathology ; Phenotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In vivo ROS production and use of oxidative stress-derived biomarkers to detect the onset of diseases such as Alzheimer's disease, Parkinson's disease, and diabetes.
Autorzy:
Umeno A; a Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) , Takamatsu , Kagawa , Japan.
Biju V; a Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) , Takamatsu , Kagawa , Japan.; b Laboratory of Molecular Photonics, Research Institute for Electronic Science, Hokkaido University, N20W10 , Kita Ward, Sapporo , Japan.
Yoshida Y; a Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) , Takamatsu , Kagawa , Japan.
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Źródło:
Free radical research [Free Radic Res] 2017 Apr; Vol. 51 (4), pp. 413-427. Date of Electronic Publication: 2017 Apr 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Oxidative Stress*
Alzheimer Disease/*metabolism
Biomarkers/*metabolism
Diabetes Mellitus/*metabolism
Parkinson Disease/*metabolism
Reactive Oxygen Species/*metabolism
Alzheimer Disease/diagnosis ; Animals ; Antioxidants/metabolism ; Diabetes Mellitus/diagnosis ; Humans ; Parkinson Disease/diagnosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intracellular accumulation of indium ions released from nanoparticles induces oxidative stress, proinflammatory response and DNA damage.
Autorzy:
Tabei Y; Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan y.
Sonoda A; Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.
Nakajima Y; Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.
Biju V; Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.
Makita Y; Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.
Yoshida Y; Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.
Horie M; Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2016 Feb; Vol. 159 (2), pp. 225-37. Date of Electronic Publication: 2015 Sep 15.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Oxidative Stress*
Inflammation/*chemically induced
Ions/*metabolism
Nanoparticles/*metabolism
Tin Compounds/*metabolism
Cell Line, Tumor ; Cell Survival/drug effects ; Comet Assay ; Humans ; Indium/chemistry ; Indium/metabolism ; Interleukin-8/metabolism ; Ions/chemistry ; Mass Spectrometry ; Microscopy, Electron, Transmission ; Nanoparticles/chemistry ; RNA, Messenger/metabolism ; Reactive Oxygen Species/metabolism ; Tin Compounds/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Switching from singlet-oxygen-mediated oxidation to free-radical-mediated oxidation in the pathogenesis of type 2 diabetes in model mouse.
Autorzy:
Murotomi K; Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) , Takamatsu, Kagawa , Japan.
Umeno A
Yasunaga M
Shichiri M
Ishida N
Abe H
Yoshida Y
Nakajima Y
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Źródło:
Free radical research [Free Radic Res] 2015 Feb; Vol. 49 (2), pp. 133-8. Date of Electronic Publication: 2014 Dec 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Oxidative Stress*
Diabetes Mellitus, Type 2/*etiology
Glucose Intolerance/*etiology
Singlet Oxygen/*chemistry
Animals ; Biomarkers/blood ; Disease Models, Animal ; Free Radicals/chemistry ; Linoleic Acids/blood ; Linoleic Acids, Conjugated/blood ; Male ; Mice ; Mice, Inbred Strains ; Mice, Obese
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cellular effects of industrial metal nanoparticles and hydrophilic carbon black dispersion.
Autorzy:
Horie M; Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST).
Kato H
Endoh S
Fujita K
Komaba LK
Nishio K
Nakamura A
Miyauchi A
Yamamoto K
Kinugasa S
Hagihara Y
Yoshida Y
Iwahashi H
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Źródło:
The Journal of toxicological sciences [J Toxicol Sci] 2014; Vol. 39 (6), pp. 897-907.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Keratinocytes/*drug effects
Lung Neoplasms/*pathology
Metal Nanoparticles/*adverse effects
Mitochondria/*drug effects
Oxidative Stress/*drug effects
Soot/*adverse effects
Cell Survival/drug effects ; Cells, Cultured ; Gold/adverse effects ; Humans ; Hydrophobic and Hydrophilic Interactions ; Keratinocytes/metabolism ; Lung Neoplasms/metabolism ; Platinum/adverse effects ; Reactive Oxygen Species/metabolism ; Silver/adverse effects ; Time Factors ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cellular responses induced by cerium oxide nanoparticles: induction of intracellular calcium level and oxidative stress on culture cells.
Autorzy:
Horie M; Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31, Midorigaoka, Ikeda, Osaka 563-8577, Japan. />Nishio K
Kato H
Fujita K
Endoh S
Nakamura A
Miyauchi A
Kinugasa S
Yamamoto K
Niki E
Yoshida Y
Hagihara Y
Iwahashi H
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Źródło:
Journal of biochemistry [J Biochem] 2011 Oct; Vol. 150 (4), pp. 461-71. Date of Electronic Publication: 2011 Jun 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium/*metabolism
Cerium/*pharmacology
Intracellular Space/*drug effects
Keratinocytes/*drug effects
Nanoparticles/*chemistry
Oxidative Stress/*drug effects
Adsorption ; Cell Survival/drug effects ; Cells, Cultured ; Humans ; Intracellular Space/metabolism ; Keratinocytes/cytology ; Keratinocytes/metabolism ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Surface Properties
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Oxidative stress and antioxidant status in older adults with early cataract.
Autorzy:
Li L; Carotenoids and Health Laboratory, Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA.
Duker JS
Yoshida Y
Niki E
Rasmussen H
Russell RM
Yeum KJ
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Źródło:
Eye (London, England) [Eye (Lond)] 2009 Jun; Vol. 23 (6), pp. 1464-8. Date of Electronic Publication: 2008 Sep 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Antioxidants/*analysis
Cataract/*blood
Oxidative Stress/*physiology
Aged ; Biomarkers/blood ; Chromatography, High Pressure Liquid/methods ; Female ; Fluorometry ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Gamma-tocopheryl quinone, not alpha-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4.
Autorzy:
Ogawa Y; Human Stress Signal Research Center (HSSRC), National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan.
Saito Y
Nishio K
Yoshida Y
Ashida H
Niki E
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Źródło:
Free radical research [Free Radic Res] 2008 Jul; Vol. 42 (7), pp. 674-87.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Activating Transcription Factor 4/*metabolism
Antioxidants/*pharmacology
Cerebral Cortex/*drug effects
Cysteine/*metabolism
Glutathione/*metabolism
Neurons/*drug effects
Oxidative Stress/*drug effects
Vitamin E/*analogs & derivatives
Activating Transcription Factor 4/genetics ; Adaptation, Physiological ; Amino Acid Transport System y+/metabolism ; Animals ; Cerebral Cortex/cytology ; Cerebral Cortex/metabolism ; Cytoprotection ; Fetus ; Glutamate-Cysteine Ligase/metabolism ; NF-E2-Related Factor 2/metabolism ; Neurons/enzymology ; Neurons/metabolism ; PC12 Cells ; RNA Interference ; RNA, Small Interfering/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Transcription, Genetic ; Up-Regulation ; Vitamin E/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Severe Vitamin E deficiency exacerbates acute hyperoxic lung injury associated with increased oxidative stress and inflammation.
Autorzy:
Yamaoka S; Department of Pediatrics, Perinatal Center, Osaka Medical College, Takatsuki, Osaka, Japan. />Kim HS
Ogihara T
Oue S
Takitani K
Yoshida Y
Tamai H
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Źródło:
Free radical research [Free Radic Res] 2008 Jun; Vol. 42 (6), pp. 602-12.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation*
Hyperoxia*
Inflammation*
Lung Injury*
Oxidative Stress*
Vitamin E Deficiency/*genetics
Animals ; Bronchoalveolar Lavage Fluid ; Carrier Proteins/metabolism ; Interleukin-6/metabolism ; Lung/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Biological ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Detection of lipid peroxidation in vivo: total hydroxyoctadecadienoic acid and 7-hydroxycholesterol as oxidative stress marker.
Autorzy:
Yoshida Y; Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, Japan 1-8-31 Midorigaoka, Ikeda, Osaka, 563-8577 Japan. yoshida />Niki E
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Źródło:
Free radical research [Free Radic Res] 2004 Aug; Vol. 38 (8), pp. 787-94.
Typ publikacji:
Journal Article
MeSH Terms:
Lipid Peroxidation*
Oxidative Stress*
Fatty Acids, Unsaturated/*blood
Hydroxycholesterols/*blood
Adult ; Biomarkers/blood ; Biomarkers/chemistry ; Chromatography, Gas ; Dinoprost/urine ; Fatty Acids, Unsaturated/chemistry ; Fatty Acids, Unsaturated/urine ; Humans ; Hydroxycholesterols/chemistry ; Male ; Mass Spectrometry ; Molecular Structure ; Oxidation-Reduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Application of water-soluble radical initiator, 2,2'-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride, to a study of oxidative stress.
Autorzy:
Yoshida Y; Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan. yoshida />Itoh N
Saito Y
Hayakawa M
Niki E
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Źródło:
Free radical research [Free Radic Res] 2004 Apr; Vol. 38 (4), pp. 375-84.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*
Amidines/*pharmacology
Oxidants/*pharmacology
Water/*chemistry
Adult ; Animals ; Cells, Cultured ; Chromans/pharmacology ; Culture Media, Serum-Free/pharmacology ; Dinoprost/analogs & derivatives ; Dinoprost/metabolism ; Dose-Response Relationship, Drug ; Erythrocytes/metabolism ; Free Radicals ; Humans ; Hydroxycholesterols/metabolism ; Jurkat Cells ; Kinetics ; Lipid Metabolism ; Lipoproteins, LDL/metabolism ; Lysophosphatidylcholines/metabolism ; Male ; Micelles ; Models, Chemical ; Oxygen/metabolism ; Rats ; Rats, Wistar ; Temperature ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 73

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