- Tytuł:
-
Frequent activation of AKT2 and induction of
apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer. - Autorzy:
- Źródło:
- Oncogene [Oncogene] 2000 May 04; Vol. 19 (19), pp. 2324-30.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
- MeSH Terms:
-
Tumor Suppressor Proteins*
Apoptosis /*physiology
Ovarian Neoplasms/*metabolism
Ovarian Neoplasms/*pathology
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins/*metabolism
Adenocarcinoma, Mucinous/metabolism ; Adenocarcinoma, Mucinous/pathology ; Adenocarcinoma, Papillary/metabolism ; Adenocarcinoma, Papillary/pathology ; Adenosarcoma/metabolism ; Adenosarcoma/pathology ; Amino Acid Sequence ; Blotting, Western ; Chromones/pharmacology ; Conserved Sequence ; Cystadenocarcinoma/metabolism ; Cystadenocarcinoma/pathology ; Female ; Fibroma/metabolism ; Fibroma/pathology ; Histones/metabolism ; Humans ; Molecular Sequence Data ; Morpholines/pharmacology ; Oncogene Proteins/metabolism ; PTEN Phosphohydrolase ; Phosphoinositide-3 Kinase Inhibitors ; Phosphoric Monoester Hydrolases/metabolism ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins/immunology ; Proto-Oncogene Proteins c-akt ; Thecoma/metabolism ; Thecoma/pathology
Czasopismo naukowe