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Tytuł:
The Intricate Balance between Life and Death: ROS, Cathepsins, and Their Interplay in Cell Death and Autophagy.
Autorzy:
Voronina MV; Research Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Frolova AS; Research Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Kolesova EP; Research Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kuldyushev NA; Research Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Parodi A; Research Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Zamyatnin AA Jr; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Department of Biological Chemistry, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 06; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cathepsins*
Autophagy*
Reactive Oxygen Species ; Cell Death ; Apoptosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Signaling and Resistosome Formation in Plant Innate Immunity to Viruses: Is There a Common Mechanism of Antiviral Resistance Conserved across Kingdoms?
Autorzy:
Ivanov PA; Faculty of Biology, Lomonosov Moscow State University, Moscow 119234, Russia.
Gasanova TV; Faculty of Biology, Lomonosov Moscow State University, Moscow 119234, Russia.
Repina MN; Faculty of Biology, Lomonosov Moscow State University, Moscow 119234, Russia.
Zamyatnin AA Jr; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow 119234, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russia.; Research Center for Translational Medicine, Sirius University of Science and Technology, Sirius 354340, Krasnodar Region, Russia.; Institute of Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow 119991, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 03; Vol. 24 (17). Date of Electronic Publication: 2023 Sep 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hypersensitivity*
Viruses*
Animals ; Signal Transduction ; Antiviral Agents ; NLR Proteins ; Phagocytosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Redox Regulation of Protein Functioning.
Autorzy:
Zamyatnin AA Jr; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Research Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sirius, Krasnodar Region, Russia.; Institute of Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
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Źródło:
Biomolecules [Biomolecules] 2023 Aug 22; Vol. 13 (9). Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:
Editorial; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Stress*
Signal Transduction*
Oxidation-Reduction ; Reactive Oxygen Species
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Smart Delivery Systems Responsive to Cathepsin B Activity for Cancer Treatment.
Autorzy:
Egorova VS; Scientific Center for Translation Medicine, Sirius University of Science and Technology, Sochi 354340, Russia.
Kolesova EP; Scientific Center for Translation Medicine, Sirius University of Science and Technology, Sochi 354340, Russia.
Lopus M; School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai Kalina Campus, Vidyanagari, Mumbai 400098, India.
Yan N; School of Environmental Studies, China University of Geosciences, Wuhan 430074, China.
Parodi A; Scientific Center for Translation Medicine, Sirius University of Science and Technology, Sochi 354340, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow 119991, Russia.
Zamyatnin AA Jr; Scientific Center for Translation Medicine, Sirius University of Science and Technology, Sochi 354340, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow 119991, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119991, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow 119991, Russia.
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Źródło:
Pharmaceutics [Pharmaceutics] 2023 Jun 29; Vol. 15 (7). Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proteolytic Resistance Determines Albumin Nanoparticle Drug Delivery Properties and Increases Cathepsin B, D, and G Expression.
Autorzy:
Kolesova EP; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Egorova VS; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Syrocheva AO; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Frolova AS; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Kostyushev D; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Kostyusheva A; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Brezgin S; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Trushina DB; Department of Biomedical Engineering, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Federal Scientific Research Center 'Crystallography and Photonics', Russian Academy of Sciences, 119333 Moscow, Russia.
Fatkhutdinova L; School of Physics, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russia.
Zyuzin M; School of Physics, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russia.
Demina PA; Federal Scientific Research Center 'Crystallography and Photonics', Russian Academy of Sciences, 119333 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Khaydukov EV; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Federal Scientific Research Center 'Crystallography and Photonics', Russian Academy of Sciences, 119333 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Zamyatnin AA Jr; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7X, UK.
Parodi A; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 16; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/metabolism
Nanoparticles*
Humans ; Cathepsin B/metabolism ; Proteolysis ; Peptide Hydrolases/metabolism ; Albumins/metabolism ; Lysosomes/metabolism ; Cathepsin D/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bacterial Therapy of Cancer: A Way to the Dustbin of History or to the Medicine of the Future?
Autorzy:
Ikryannikova LN; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya 8/2, 119991 Moscow, Russia.
Gorokhovets NV; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya 8/2, 119991 Moscow, Russia.
Belykh DA; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya 8/2, 119991 Moscow, Russia.
Kurbatov LK; Orekhovich Research Institute of Biomedical Chemistry, Pogodinskaya 10/8, 119991 Moscow, Russia.
Zamyatnin AA Jr; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya 8/2, 119991 Moscow, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Leninskie Gory 1/73, 119234 Moscow, Russia.; Belozersky Research Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1/40, 119992 Moscow, Russia.; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 1 Olympic Ave, 354340 Sochi, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 03; Vol. 24 (11). Date of Electronic Publication: 2023 Jun 03.
Typ publikacji:
Historical Article; Journal Article; Review
MeSH Terms:
Medicine*
Neoplasms*/therapy
Humans ; Bacteria
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PD-L1 stimulation can promote proliferation and survival of leukemic cells by influencing glucose and fatty acid metabolism in acute myeloid leukemia.
Autorzy:
Soltani M; Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Ghanadian M; Department of Pharmacognosy, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran.
Ghezelbash B; Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Shokouhi A; Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Zamyatnin AA Jr; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, Sochi, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.; Department of Immunology Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Bazhin AV; Department of General, Visceral and Transplant Surgery, Ludwig Maximilians University of Munich, Munich, Germany.
Ganjalikhani-Hakemi M; Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. .; Department of Immunology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey. .
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Źródło:
BMC cancer [BMC Cancer] 2023 May 16; Vol. 23 (1), pp. 447. Date of Electronic Publication: 2023 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/metabolism
Leukemia, Myeloid, Acute*/metabolism
Humans ; Glucose/metabolism ; HL-60 Cells ; Cell Proliferation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hydroxychloroquine Enhances Cytotoxic Properties of Extracellular Vesicles and Extracellular Vesicle-Mimetic Nanovesicles Loaded with Chemotherapeutics.
Autorzy:
Brezgin S; Laboratory of Genetic Technologies, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.; Division of Biotechnology, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kostyusheva A; Laboratory of Genetic Technologies, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Ponomareva N; Laboratory of Genetic Technologies, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.; Division of Biotechnology, Sirius University of Science and Technology, 354340 Sochi, Russia.
Bayurova E; Chumakov Federal Scientific Center for Research and Development of Immunobiological Products, Russian Academy of Sciences (Polio Institute), 108819 Moscow, Russia.
Kondrashova A; Chumakov Federal Scientific Center for Research and Development of Immunobiological Products, Russian Academy of Sciences (Polio Institute), 108819 Moscow, Russia.
Frolova A; Division of Biotechnology, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Slatinskaya O; Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Fatkhutdinova L; School of Physics, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russia.
Maksimov G; Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Zyuzin M; School of Physics, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russia.
Gordeychuk I; Chumakov Federal Scientific Center for Research and Development of Immunobiological Products, Russian Academy of Sciences (Polio Institute), 108819 Moscow, Russia.
Lukashev A; Laboratory of Genetic Technologies, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Makarov S; School of Physics, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russia.; Qingdao Innovation and Development Center, Harbin Engineering University, Harbin 150001, China.; Qingdao Innovation and Development Center, Harbin Engineering University, Qingdao 266000, China.
Ivanov A; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Zamyatnin AA Jr; Division of Biotechnology, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.; Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7X, UK.
Chulanov V; Laboratory of Genetic Technologies, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.; Division of Biotechnology, Sirius University of Science and Technology, 354340 Sochi, Russia.; Department of Infectious Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Parodi A; Division of Biotechnology, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kostyushev D; Laboratory of Genetic Technologies, Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.; Division of Biotechnology, Sirius University of Science and Technology, 354340 Sochi, Russia.
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Źródło:
Pharmaceutics [Pharmaceutics] 2023 Feb 05; Vol. 15 (2). Date of Electronic Publication: 2023 Feb 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cathepsin K in Pathological Conditions and New Therapeutic and Diagnostic Perspectives.
Autorzy:
Mijanović O; Dia-M, LCC, 7 b.3 Magadanskaya Str., 129345 Moscow, Russia.; The Human Pathology Department, Sechenov First Moscow State University, 119991 Moscow, Russia.
Jakovleva A; HoxLife Science GmbH, Gutleutstraße 169-171, 60327 Frankfurt am Main, Germany.
Branković A; Department of Forensics Engineering, University of Criminal Investigation and Police Studies, Cara Dusana 196, 11000 Belgrade, Serbia.
Zdravkova K; AD Alkaloid Skopje, Boulevar Alexander the Great 12, 1000 Skopje, North Macedonia.
Pualic M; Institute Cardiovascular Diseases Dedinje, Heroja Milana Tepica 1, 11000 Belgrade, Serbia.
Belozerskaya TA; Bach Institute of Biochemistry, Research Center of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.
Nikitkina AI; ArhiMed Clinique for New Medical Technologies, Vavilova St. 68/2, 119261 Moscow, Russia.
Parodi A; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Zamyatnin AA Jr; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7X, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 09; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Collagen Type I*/metabolism
Cysteine Proteases*
Cathepsin K/metabolism ; Bone and Bones/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anticancer Nanotherapeutics in Clinical Trials: The Work behind Clinical Translation of Nanomedicine.
Autorzy:
Parodi A; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Kolesova EP; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Voronina MV; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Frolova AS; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Kostyushev D; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Trushina DB; Institute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Federal Scientific Research Center «Crystallography and Photonics», Russian Academy of Sciences, 119333 Moscow, Russia.
Akasov R; Institute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Federal Scientific Research Center «Crystallography and Photonics», Russian Academy of Sciences, 119333 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Pallaeva T; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Federal Scientific Research Center «Crystallography and Photonics», Russian Academy of Sciences, 119333 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Zamyatnin AA Jr; Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 02; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Nanoparticles*/therapeutic use
Neoplasms*/drug therapy
Humans ; Nanomedicine ; Nanotechnology ; Drug Delivery Systems
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cancer-Retina Antigens in the Urine of Bladder and Prostate Cancer Patients.
Autorzy:
Shlyapnikov YM; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, 142290, Russia. .
Malakhova EA; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, 142290, Russia.
Vinarov AZ; Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Moscow, 119991, Russia.
Potoldykova NV; Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Moscow, 119991, Russia.
Vladimirov VI; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117437, Russia.
Zernii EY; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.
Zamyatnin AA Jr; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, 119991, Russia.; Department of Biotechnology, Sirius University of Science and Technology, Krasnodar Region, Federal Territory Sirius, 354340, Russia.
Shlyapnikova EA; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, 142290, Russia.
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Źródło:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2022 Nov; Vol. 87 (11), pp. 1268-1276.
Typ publikacji:
Journal Article
MeSH Terms:
Urinary Bladder Neoplasms*/diagnosis
Prostatic Neoplasms*/diagnosis
Male ; Humans ; Urinary Bladder ; Biomarkers, Tumor ; Sensitivity and Specificity ; Antigens, Neoplasm
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Physiologically Based Pharmacokinetic Modeling of Nanoparticle Biodistribution: A Review of Existing Models, Simulation Software, and Data Analysis Tools.
Autorzy:
Kutumova EO; Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; Federal Research Center for Information and Computational Technologies, 630090 Novosibirsk, Russia.; BIOSOFT.RU, Ltd., 630058 Novosibirsk, Russia.
Akberdin IR; Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; BIOSOFT.RU, Ltd., 630058 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Kiselev IN; Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; Federal Research Center for Information and Computational Technologies, 630090 Novosibirsk, Russia.; BIOSOFT.RU, Ltd., 630058 Novosibirsk, Russia.
Sharipov RN; Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; Federal Research Center for Information and Computational Technologies, 630090 Novosibirsk, Russia.; BIOSOFT.RU, Ltd., 630058 Novosibirsk, Russia.; Specialized Educational Scientific Center, Novosibirsk State University, 630090 Novosibirsk, Russia.
Egorova VS; Scientific Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Syrocheva AO; Scientific Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.
Parodi A; Scientific Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Zamyatnin AA Jr; Scientific Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Kolpakov FA; Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; Federal Research Center for Information and Computational Technologies, 630090 Novosibirsk, Russia.; BIOSOFT.RU, Ltd., 630058 Novosibirsk, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 19; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Nanoparticles*/chemistry
Neoplasms*/pathology
Biological Products*
Humans ; Tissue Distribution ; Data Analysis ; Artificial Intelligence ; Models, Biological ; Computer Simulation ; Software
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
New Advances in the Understanding of Proteases as Diagnostic and Pharmaceutical Targets in Homeostatic and Pathologic Conditions.
Autorzy:
Zamyatnin AA Jr; Biotechnology Department, Sirius University of Science and Technology, Olympic Avenue, 1, 354349 Sirius, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7X, UK.
Parodi A; Biotechnology Department, Sirius University of Science and Technology, Olympic Avenue, 1, 354349 Sirius, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
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Źródło:
Pharmaceutics [Pharmaceutics] 2022 Jul 21; Vol. 14 (7). Date of Electronic Publication: 2022 Jul 21.
Typ publikacji:
Editorial
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Non-Invasive Diagnostics of Renal Cell Carcinoma Using Ultrasensitive Immunodetection of Cancer-Retina Antigens.
Autorzy:
Shlyapnikov YM; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. .
Malakhova EA; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. .
Potoldykova NV; Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Moscow, 119991, Russia. .
Svetocheva YA; Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Moscow, 119991, Russia. .
Vinarov AZ; Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Moscow, 119991, Russia. .
Zinchenko DV; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Moscow Region, 117997, Russia. .
Zernii EY; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia. .
Zamyatnin AA Jr; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia. .; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, 119991, Russia.; Department of Biotechnology, Sirius University of Science and Technology, Sochi, 354340, Russia.; Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Shlyapnikova EA; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. .
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Źródło:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2022 Jul; Vol. 87 (7), pp. 658-666.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/diagnosis
Carcinoma, Renal Cell*/pathology
Kidney Neoplasms*/diagnosis
Kidney Neoplasms*/pathology
Arrestins ; Biomarkers, Tumor ; G-Protein-Coupled Receptor Kinase 1 ; Humans ; Recoverin ; Retina ; Transducin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Robust AAV Genotyping Based on Genetic Distances in Rep Gene That Are Maintained by Ubiquitous Recombination.
Autorzy:
Beloukhova MI; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Lukashev AN; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Volchkov PY; Genome Engineering Lab, Moscow Institute of Physics and Technology (National Research University), 141700 Dolgoprudniy, Russia.; The National Medical Research Center for Endocrinology, 117036 Moscow, Russia.
Zamyatnin AA Jr; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave, 354340 Sochi, Russia.; Department of Immunology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.
Deviatkin AA; Genome Engineering Lab, Moscow Institute of Physics and Technology (National Research University), 141700 Dolgoprudniy, Russia.; The National Medical Research Center for Endocrinology, 117036 Moscow, Russia.; Laboratory of Postgenomic Technologies, Izmerov Research Institute of Occupational Health, 105275 Moscow, Russia.
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Źródło:
Viruses [Viruses] 2022 May 13; Vol. 14 (5). Date of Electronic Publication: 2022 May 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dependovirus*
Gene Transfer Techniques*
Genotype ; Phylogeny ; Recombination, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Silico, In Vitro, and Clinical Investigations of Cathepsin B and Stefin A mRNA Expression and a Correlation Analysis in Kidney Cancer.
Autorzy:
Rudzinska-Radecka M; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Institute of Physical Chemistry, Polish Academy of Sciences, 01-224 Warsaw, Poland.
Frolova AS; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.
Balakireva AV; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997 Moscow, Russia.
Gorokhovets NV; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Pokrovsky VS; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.; Laboratory of Combined Treatment, N.N. Blokhin Cancer Research Center, 115478 Moscow, Russia.; Department of Biochemistry, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.
Sokolova DV; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.; Laboratory of Combined Treatment, N.N. Blokhin Cancer Research Center, 115478 Moscow, Russia.; Department of Biochemistry, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.
Korolev DO; Institute for Urology and Reproductive Health, Sechenov University, 119992 Moscow, Russia.
Potoldykova NV; Institute for Urology and Reproductive Health, Sechenov University, 119992 Moscow, Russia.
Vinarov AZ; Institute for Urology and Reproductive Health, Sechenov University, 119992 Moscow, Russia.
Parodi A; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.
Zamyatnin AA Jr; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave., 354340 Sochi, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Department of Immunology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.
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Źródło:
Cells [Cells] 2022 Apr 25; Vol. 11 (9). Date of Electronic Publication: 2022 Apr 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Renal Cell*/genetics
Cystatins*/metabolism
Kidney Neoplasms*/genetics
Cathepsin B/*metabolism
Cystatin A/*metabolism
Cathepsin B/genetics ; Cystatin A/genetics ; Female ; Humans ; Male ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disulfide Dimerization of Neuronal Calcium Sensor-1: Implications for Zinc and Redox Signaling.
Autorzy:
Baksheeva VE; Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Baldin AV; Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Department of General, Visceral, and Transplant Surgery, Ludwig Maximilians University Munich, 81377 Munich, Germany.; V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, 117997 Moscow, Russia.
Zalevsky AO; Shemyakin Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Nazipova AA; Institute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Kazakov AS; Institute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Vladimirov VI; Shemyakin Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Gorokhovets NV; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Devred F; Institut de Neurophysiopathologie, INP, CNRS, Faculté des Sciences Médicales et Paramédicales, Aix-Marseille Université, 13005 Marseille, France.; Plateforme Interactome Timone, PINT, Faculté des Sciences Médicales et Paramédicales, Aix Marseille Université, 13009 Marseille, France.
Philippov PP; Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Bazhin AV; Department of General, Visceral, and Transplant Surgery, Ludwig Maximilians University Munich, 81377 Munich, Germany.; Partner Site Munich, German Cancer Consortium (DKTK), 80336 Munich, Germany.
Golovin AV; Shemyakin Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.; Sirius University of Science and Technology, 354340 Sochi, Russia.
Zamyatnin AA Jr; Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Sirius University of Science and Technology, 354340 Sochi, Russia.; Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, Surrey, UK.
Zinchenko DV; Shemyakin Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Tsvetkov PO; Institut de Neurophysiopathologie, INP, CNRS, Faculté des Sciences Médicales et Paramédicales, Aix-Marseille Université, 13005 Marseille, France.; Plateforme Interactome Timone, PINT, Faculté des Sciences Médicales et Paramédicales, Aix Marseille Université, 13009 Marseille, France.
Permyakov SE; Institute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Zernii EY; Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 22; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Signaling/*genetics
G-Protein-Coupled Receptor Kinase 1/*genetics
Neoplasms/*genetics
Neuronal Calcium-Sensor Proteins/*genetics
Neurons/*metabolism
Neuropeptides/*genetics
Calcium/metabolism ; Calcium-Binding Proteins/genetics ; Cell Line, Tumor ; Dimerization ; Disulfides/chemistry ; EF Hand Motifs/genetics ; HEK293 Cells ; Humans ; Kinetics ; Neoplasms/pathology ; Neuronal Calcium-Sensor Proteins/antagonists & inhibitors ; Neurons/chemistry ; Neuropeptides/antagonists & inhibitors ; Oxidation-Reduction ; Receptors, G-Protein-Coupled/genetics ; Signal Transduction/genetics ; Zinc/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BH3-mimetics: recent developments in cancer therapy.
Autorzy:
Townsend PA; University of Surrey, Guildford, UK. .; Sechenov First Moscow State Medical University, Moscow, Russian Federation. .; University of Manchester, Manchester, UK. .
Kozhevnikova MV; University of Surrey, Guildford, UK.; Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Cexus ONF; University of Surrey, Guildford, UK.
Zamyatnin AA Jr; University of Surrey, Guildford, UK.; Sechenov First Moscow State Medical University, Moscow, Russian Federation.; Lomonosov Moscow State University, Moscow, Russian Federation.; Sirius University of Science and Technology, Sochi, Russian Federation.
Soond SM; University of Surrey, Guildford, UK. .; Sechenov First Moscow State Medical University, Moscow, Russian Federation. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2021 Nov 09; Vol. 40 (1), pp. 355. Date of Electronic Publication: 2021 Nov 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Mitochondrial Membrane Transport Proteins/*metabolism
Neoplasms/*therapy
Humans ; Models, Molecular
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nanomedicine for increasing the oral bioavailability of cancer treatments.
Autorzy:
Parodi A; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia. .; Sirius University of Science and Technology, 1 Olympic Ave, 354340, Sochi, Russia. .
Buzaeva P; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia.
Nigovora D; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia.
Baldin A; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992, Moscow, Russia.
Kostyushev D; Sirius University of Science and Technology, 1 Olympic Ave, 354340, Sochi, Russia.; National Medical Research Center of Tuberculosis and Infectious Diseases, Ministry of Health, 127994, Moscow, Russia.
Chulanov V; Sirius University of Science and Technology, 1 Olympic Ave, 354340, Sochi, Russia.; National Medical Research Center of Tuberculosis and Infectious Diseases, Ministry of Health, 127994, Moscow, Russia.; Department of Infectious Diseases, Sechenov University, 119991, Moscow, Russia.
Savvateeva LV; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia.
Zamyatnin AA Jr; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia. .; Sirius University of Science and Technology, 1 Olympic Ave, 354340, Sochi, Russia. .; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992, Moscow, Russia. .; Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7X, UK. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2021 Oct 30; Vol. 19 (1), pp. 354. Date of Electronic Publication: 2021 Oct 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Nanomedicine*
Antineoplastic Agents/*pharmacology
Neoplasms/*drug therapy
Administration, Oral ; Animals ; Antineoplastic Agents/chemistry ; Biological Availability ; Drug Delivery Systems ; Humans ; Pharmaceutical Preparations
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cathepsin D-Managing the Delicate Balance.
Autorzy:
Mijanovic O; Institute for Regenerative Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Petushkova AI; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Laboratory of Nanomedicine, Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave, 354340 Sochi, Russia.
Brankovic A; Department of Forensic Engineering, University of Criminal Investigation and Police Studies, 11080 Belgrade, Serbia.
Turk B; Institute for Regenerative Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department of Biochemistry and Molecular and Structural Biology, J. Stefan Institute, 1000 Ljubljana, Slovenia.; Faculty of Chemistry and Chemical Technology, University of Ljubljana, 1000 Ljubljana, Slovenia.
Solovieva AB; Semenov Institute of Chemical Physics, Russian Academy of Sciences, 119991 Moscow, Russia.
Nikitkina AI; Institute for Regenerative Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Bolevich S; Department of Human Pathology, Sechenov University, 119991 Moscow, Russia.
Timashev PS; Institute for Regenerative Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Semenov Institute of Chemical Physics, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Chemistry, Lomonosov Moscow State University, 119234 Moscow, Russia.; World-Class Research Center 'Digital Biodesign and Personalized Healthcare', Sechenov University, 119991 Moscow, Russia.
Parodi A; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Laboratory of Nanomedicine, Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave, 354340 Sochi, Russia.
Zamyatnin AA Jr; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Laboratory of Nanomedicine, Department of Biotechnology, Sirius University of Science and Technology, 1 Olympic Ave, 354340 Sochi, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
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Źródło:
Pharmaceutics [Pharmaceutics] 2021 Jun 05; Vol. 13 (6). Date of Electronic Publication: 2021 Jun 05.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 57

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