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Wyświetlanie 1-20 z 91
Tytuł:
Disease-associated astrocyte epigenetic memory promotes CNS pathology
Autorzy:
Lee, Hong-Gyun
Rone, Joseph M.
Li, ZhaorongAff1, Aff2
Akl, Camilo Faust
Shin, Seung Won
Lee, Joon-Hyuk
Flausino, Lucas E.
Pernin, Florian
Chao, Chun-Cheih
Kleemann, Kilian L.
Srun, Lena
Illouz, Tomer
Giovannoni, Federico
Charabati, Marc
Sanmarco, Liliana M.
Kenison, Jessica E.
Piester, GavinAff1, Aff6
Zandee, Stephanie E. J.
Antel, Jack P.
Rothhammer, VeitAff1, Aff8
Wheeler, Michael A.Aff1, Aff2
Prat, Alexandre
Clark, Iain C.
Quintana, Francisco J.Aff1, Aff2, Aff9, IDs41586024071875_cor24
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Źródło:
Nature: International weekly journal of science. 627(8005):865-872
Czasopismo naukowe
Szczegóły
Tytuł:
Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
Autorzy:
Jhelum, Priya
Zandee, StephanieAff2, Aff3
Ryan, Fari
Zarruk, Juan G.
Michalke, Bernhard
Venkataramani, Vivek
Curran, Laura
Klement, WendyAff2, Aff3
Prat, AlexandreAff2, Aff3
David, SamuelAff1, IDs40478023016177_cor10
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Źródło:
Acta Neuropathologica Communications. 11(1)
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Droplet-based forward genetic screening of astrocyte-microglia cross-talk.
Autorzy:
Wheeler MA; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Clark IC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Bioengineering, College of Engineering, California Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, CA 94720, USA.
Lee HG; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Li Z; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Linnerbauer M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Rone JM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Blain M; Neuroimmunology Unit, Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Akl CF; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Piester G; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Giovannoni F; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Charabati M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Lee JH; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Kye YC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Choi J; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Sanmarco LM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Srun L; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Chung EN; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Flausino LE; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Andersen BM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Jamaica Plain Veterans Affairs Hospital, Harvard Medical School, Boston, MA 02130, USA.
Rothhammer V; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuernberg, Erlangen, Germany.
Yano H; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Joan and Sanford I. Weill Department of Medicine, Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.
Illouz T; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Zandee SEJ; Neuroimmunology Research Lab, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, QC H2X 0A9, Canada.
Daniel C; Type 1 Diabetes Immunology, Helmholtz Diabetes Center at Helmholtz Zentrum München, 80939 Munich, Germany.; Deutsches Zentrum für Diabetesforschung, 85764 Munich-Neuherberg, Germany.; Division of Clinical Pharmacology, Department of Medicine IV, Ludwig-Maximilians-Universität München, 80337 Munich, Germany.
Artis D; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Joan and Sanford I. Weill Department of Medicine, Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.; Friedman Center for Nutrition and Inflammation, Joan and Sanford I. Weill Department of Medicine, Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.
Prinz M; Institute of Neuropathology, University of Freiburg, D-79106 Freiburg, Germany.; Signaling Research Centres BIOSS and CIBSS, University of Freiburg, D-79106 Freiburg, Germany.; Center for Basics in NeuroModulation, Faculty of Medicine, University of Freiburg, D-79106 Freiburg, Germany.
Abate AR; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California Institute for Quantitative Biosciences, San Francisco, CA 94158, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.
Kuchroo VK; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Antel JP; Neuroimmunology Unit, Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Prat A; Neuroimmunology Research Lab, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, QC H2X 0A9, Canada.
Quintana FJ; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Mar 10; Vol. 379 (6636), pp. 1023-1030. Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/physiology
Genetic Testing*/methods
Microfluidic Analytical Techniques*/methods
Microglia*/physiology
Amphiregulin*/genetics
Autocrine Communication*/genetics
High-Throughput Screening Assays ; Gene Expression ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of astrocyte regulators by nucleic acid cytometry
Autorzy:
Clark, Iain C.Aff1, Aff2, Aff3
Wheeler, Michael A.Aff1, Aff4
Lee, Hong-Gyun
Li, ZhaorongAff1, Aff4
Sanmarco, Liliana M.
Thaploo, Shravan
Polonio, Carolina M.
Shin, Seung Won
Scalisi, Giulia
Henry, Amy R.
Rone, Joseph M.
Giovannoni, Federico
Charabati, Marc
Akl, Camilo Faust
Aleman, Dulce M.
Zandee, Stephanie E. J.
Prat, Alexandre
Douek, Daniel C.
Boritz, Eli A.
Quintana, Francisco J.Aff1, Aff4, IDs41586022056130_cor20
Abate, Adam R.Aff2, IDs41586022056130_cor21
Pokaż więcej
Źródło:
Nature: International weekly journal of science. 614(7947):326-333
Czasopismo naukowe
Szczegóły
Tytuł:
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis.
Autorzy:
Licht-Mayer S; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Campbell GR; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Mehta AR; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.
McGill K; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Symonds A; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Al-Azki S; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Pryce G; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Zandee S; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
Zhao C; Wellcome Trust-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Kipp M; Institute of Anatomy, Rostock University Medical Center, Rostock, Germany.
Smith KJ; Department of Neuroinflammation, The UCL Queen Square Institute of Neurology, University College London, London, UK.
Baker D; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Altmann D; Faculty of Medicine, Department of Medicine, Hammersmith Campus, London, UK.
Anderton SM; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
Kap YS; Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Laman JD; Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.; Department Pathology and Medical Biology and MS Center Noord Nederland (MSCNN), University Groningen, University Medical Center Groningen, Groningen, The Netherlands.
't Hart BA; Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.; Department Pathology and Medical Biology and MS Center Noord Nederland (MSCNN), University Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department Anatomy and Neuroscience, Amsterdam University Medical Center (VUMC), Amsterdam, Netherlands.
Rodriguez M; Department of Neurology and Immunology, Mayo College of Medicine and Science, Rochester, Minnesota, USA.
Franklin RJM; Wellcome Trust-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Chandran S; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.
Lassmann H; Department of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Trapp BD; Department of Neuroscience, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Mahad DJ; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
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Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2023 Feb; Vol. 49 (1), pp. e12851. Date of Electronic Publication: 2022 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*/pathology
Encephalomyelitis, Autoimmune, Experimental*/pathology
Animals ; Axons/pathology ; Neurons/pathology ; Mitochondria/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Single-Cell Transcriptomics Identifies Brain Endothelium Inflammatory Networks in Experimental Autoimmune Encephalomyelitis.
Autorzy:
Fournier, Antoine Philippe
Tastet, Olivier
Charabati, Marc
Hoornaert, Chloé
Bourbonnière, Lyne
Klement, Wendy
Larouche, Sandra
Tea, Fiona
Wang, Yu Chang
Larochelle, Catherine
Arbour, Nathalie
Ragoussis, Jiannis
Zandee, Stephanie
Prat, Alexandre
Pokaż więcej
Źródło:
Neurology® Neuroimmunology & Neuroinflammation; Jan2023, Vol. 10 Issue 1, p1-13, 13p
Czasopismo naukowe
Szczegóły
Tytuł:
CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis.
Autorzy:
Fournier, Antoine Philippe
Zandee, Stephanie
Charabati, Marc
Peelen, Evelyn
Tastet, Olivier
Alvarez, Jorge Ivan
Kebir, Hania
Bourbonnière, Lyne
Larouche, Sandra
Lahav, Boaz
Klement, Wendy
Tea, Fiona
Bouthillier, Alain
Moumdjian, Robert
Cayrol, Romain
Duquette, Pierre
Girard, Marc
Larochelle, Catherine
Arbour, Nathalie
Prat, Alexandre
Pokaż więcej
Źródło:
Neurology® Neuroimmunology & Neuroinflammation; Nov2022, Vol. 9 Issue 6, p1-12, 12p
Czasopismo naukowe
Szczegóły
Tytuł:
Oncostatin M triggers brain inflammation by compromising blood–brain barrier integrity
Autorzy:
Hermans, DoryssaAff1, Aff2
Houben, EvelienAff1, Aff2
Baeten, PaulienAff1, Aff2
Slaets, HelenaAff1, Aff2
Janssens, KrisAff1, Aff2
Hoeks, CindyAff1, Aff2
Hosseinkhani, BaharakAff1, Aff2
Duran, GayelAff1, Aff2
Bormans, Seppe
Gowing, Elizabeth
Hoornaert, Chloé
Beckers, LienAff1, Aff5
Fung, Wing Ka
Schroten, Horst
Ishikawa, Hiroshi
Fraussen, JudithAff1, Aff5
Thoelen, Ronald
de Vries, Helga E.
Kooij, Gijs
Zandee, Stephanie
Prat, Alexandre
Hellings, NielsAff1, Aff2
Broux, BiekeAff1, Aff2, Aff9, IDs00401022024450_cor23
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Źródło:
Acta Neuropathologica: Pathology and Mechanisms of Neurological Disease. 144(2):259-281
Czasopismo naukowe
Szczegóły
Tytuł:
Stress Signal ULBP4, an NKG2D Ligand, Is Upregulated in Multiple Sclerosis and Shapes CD8 + T-Cell Behaviors.
Autorzy:
Carmena Moratalla, Ana
Carpentier Solorio, Yves
Lemaitre, Florent
Farzam-kia, Negar
Levert, Annie
Zandee, Stephanie E.J.
Lahav, Boaz
Guimond, Jean Victor
Haddad, Elie
Girard, Marc
Duquette, Pierre
Larochelle, Catherine
Prat, Alexandre
Arbour, Nathalie
Pokaż więcej
Źródło:
Neurology® Neuroimmunology & Neuroinflammation; Jan2022, Vol. 9 Issue 1, p1-12, 12p
Czasopismo naukowe
Szczegóły
Tytuł:
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites
Autorzy:
Tokarew, Jacqueline M.Aff1, Aff2
El-Kodsi, Daniel N.Aff1, Aff2
Lengacher, Nathalie A.Aff1, Aff2
Fehr, Travis K.Aff1, Aff2
Nguyen, Angela P.
Shutinoski, Bojan
O’Nuallain, Brian
Jin, Ming
Khan, Jasmine M.
Ng, Andy C. H.
Li, Juan
Jiang, Qiubo
Zhang, Mei
Wang, Liqun
Sengupta, RajibAff5, Aff6
Barber, Kathryn R.
Tran, An
Im, Doo SoonAff20, Aff21
Callaghan, Steve
Park, David S.Aff20, Aff21
Zandee, Stephanie
Dong, Xiajun
Scherzer, Clemens R.
Prat, Alexandre
Tsai, Eve C.Aff1, Aff10
Takanashi, Masashi
Hattori, Nobutaka
Chan, Jennifer A.
Zecca, Luigi
West, Andrew B.Aff14, Aff15
Holmgren, Arne
Puente, Lawrence
Shaw, Gary S.
Toth, Gergely
Woulfe, John M.Aff1, Aff4
Taylor, Peggy
Tomlinson, Julianna J.Aff1, Aff18
Schlossmacher, Michael G.Aff1, Aff18, Aff19
Pokaż więcej
Źródło:
Acta Neuropathologica: Pathology and Mechanisms of Neurological Disease. 141(5):725-754
Czasopismo naukowe
Szczegóły
Tytuł:
Barcoded viral tracing of single-cell interactions in central nervous system inflammation.
Autorzy:
Clark IC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Bioengineering, University of California, Berkeley, California Institute for Quantitative Biosciences, Berkeley, CA 94720, USA.
Gutiérrez-Vázquez C; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Wheeler MA; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Li Z; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Rothhammer V; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Linnerbauer M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Sanmarco LM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Guo L; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Blain M; Neuroimmunology Unit, Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Zandee SEJ; Neuroimmunology Research Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Chao CC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Batterman KV; Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA.
Schwabenland M; Institute of Neuropathology, University of Freiburg, D-79106 Freiburg, Germany.
Lotfy P; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Tejeda-Velarde A; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Hewson P; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Manganeli Polonio C; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Shultis MW; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Salem Y; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Tjon EC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Fonseca-Castro PH; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Borucki DM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Alves de Lima K; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Plasencia A; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Abate AR; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California Institute for Quantitative Biosciences, San Francisco, CA 94158, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.
Rosene DL; Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA.
Hodgetts KJ; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Prinz M; Institute of Neuropathology, University of Freiburg, D-79106 Freiburg, Germany.; Signaling Research Centres BIOSS and CIBSS, University of Freiburg, D-79106 Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, D-79106 Freiburg, Germany.
Antel JP; Neuroimmunology Unit, Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Prat A; Neuroimmunology Research Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Quintana FJ; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. .; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2021 Apr 23; Vol. 372 (6540).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Communication*
Single-Cell Analysis*
Astrocytes/*physiology
Central Nervous System/*pathology
Encephalomyelitis, Autoimmune, Experimental/*physiopathology
Microglia/*physiology
Multiple Sclerosis/*physiopathology
Animals ; Antigens, CD/metabolism ; Brain/pathology ; Brain/physiopathology ; Central Nervous System/physiopathology ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Ephrin-B3/metabolism ; Herpesvirus 1, Suid/genetics ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondria/metabolism ; Multiple Sclerosis/pathology ; NF-kappa B/metabolism ; Nerve Tissue Proteins/metabolism ; RNA-Seq ; Reactive Oxygen Species/metabolism ; Receptor, EphB3/antagonists & inhibitors ; Receptor, EphB3/metabolism ; Receptors, Cell Surface/metabolism ; Semaphorins/metabolism ; Signal Transduction ; T-Lymphocytes/physiology ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gut-licensed IFNγ anti-inflammatory astrocytes
Autorzy:
Sanmarco, Liliana M.
Wheeler, Michael A.Aff1, Aff2
Gutiérrez-Vázquez, Cristina
Polonio, Carolina Manganeli
Linnerbauer, Mathias
Pinho-Ribeiro, Felipe A.
Li, ZhaorongAff1, Aff2
Giovannoni, Federico
Batterman, Katelyn V.
Scalisi, Giulia
Zandee, Stephanie E. J.Aff5, Aff6
Heck, Evelyn S.
Alsuwailm, MoneeraAff1, Aff7
Rosene, Douglas L.
Becher, Burkhard
Chiu, Isaac M.
Prat, AlexandreAff5, Aff6
Quintana, Francisco J.Aff1, Aff2
Pokaż więcej
Źródło:
Nature: International weekly journal of science. 590(7846):473-479
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 91

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