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    Wyświetlanie 1-6 z 6
    Tytuł:
    Transcriptomic Analysis of the Effect of Torin-2 on the Central Nervous System of Drosophila melanogaster .
    Autorzy:
    Vershinina YS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Krasnov GS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Shaposhnikov MV; Institute of Biology, Komi Science Center, Ural Branch of RAS, 167000 Syktyvkar, Russia.
    Fedorova MS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Pudova EA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Katunina IV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Kornev AB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Zemskaya NV; Institute of Biology, Komi Science Center, Ural Branch of RAS, 167000 Syktyvkar, Russia.
    Kudryavtsev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Bulavkina EV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Matveeva AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Ulyasheva NS; Institute of Biology, Komi Science Center, Ural Branch of RAS, 167000 Syktyvkar, Russia.
    Guvatova ZG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Anurov AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Moskalev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
    Kudryavtseva AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 May 22; Vol. 24 (10). Date of Electronic Publication: 2023 May 22.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Drosophila melanogaster*/genetics
    Drosophila melanogaster*/metabolism
    TOR Serine-Threonine Kinases*/metabolism
    Male ; Animals ; Female ; Transcriptome ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Sirolimus/pharmacology ; Central Nervous System/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Studying the Geroprotective Properties of YAP/TAZ Signaling Inhibitors on Drosophila melanogaster Model.
    Autorzy:
    Golubev DA; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Center, Ural Branch, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
    Zemskaya NV; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Center, Ural Branch, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
    Gorbunova AA; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Center, Ural Branch, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
    Kukuman DV; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Center, Ural Branch, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
    Moskalev A; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Center, Ural Branch, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
    Shaposhnikov MV; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Center, Ural Branch, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 Mar 22; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 22.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Drosophila melanogaster*/genetics
    Drosophila melanogaster*/metabolism
    Antineoplastic Agents*
    Animals ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; YAP-Signaling Proteins ; Transcriptional Coactivator with PDZ-Binding Motif Proteins ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Drosophila/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.
    Autorzy:
    Shaposhnikov MV; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Guvatova ZG; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russian Federation.
    Zemskaya NV; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Koval LA; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Schegoleva EV; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Gorbunova AA; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Golubev DA; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Pakshina NR; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Ulyasheva NS; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Solovev IA; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation.
    Bobrovskikh MA; Laboratory of Stress Genetics, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Lavrentiev avenue 10, Novosibirsk, 630090, Russian Federation.
    Gruntenko NE; Laboratory of Stress Genetics, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Lavrentiev avenue 10, Novosibirsk, 630090, Russian Federation.
    Menshanov PN; Physiology Department, Novosibirsk State University, Pirogova 1, Novosibirsk, 630090, Russian Federation.; Laser Systems Department, Novosibirsk State Technical University, Karl Marx avenue 20, Novosibirsk, 630073, Russian Federation.
    Krasnov GS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russian Federation.
    Kudryavseva AV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russian Federation.
    Moskalev AA; Laboratory of Geroprotective and Radioprotective Technologies, Institute of Biology, Komi Science Centre, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russian Federation. .; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russian Federation. .
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    Źródło:
    Communications biology [Commun Biol] 2022 Jun 09; Vol. 5 (1), pp. 566. Date of Electronic Publication: 2022 Jun 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Drosophila melanogaster*/genetics
    Longevity*/genetics
    Aging/physiology ; Animals ; Autophagy ; Genotype
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Comparative Metabolomic Study of Drosophila Species with Different Lifespans.
    Autorzy:
    Maslov DL; Analytical Branch, Institute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.
    Zemskaya NV; Laboratory of Geroprotective and Radioprotective Technologies, Komi Science Center, Institute of Biology, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
    Trifonova OP; Analytical Branch, Institute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.
    Lichtenberg S; Analytical Branch, Institute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.; Metabometrics Inc., 651 N Broad Street, Suite 205 #1370, Middletown, DE 19709, USA.
    Balashova EE; Analytical Branch, Institute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.
    Lisitsa AV; Analytical Branch, Institute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.
    Moskalev AA; Laboratory of Geroprotective and Radioprotective Technologies, Komi Science Center, Institute of Biology, Russian Academy of Sciences, 167982 Syktyvkar, Russia.
    Lokhov PG; Analytical Branch, Institute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Nov 28; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 28.
    Typ publikacji:
    Comparative Study; Journal Article
    MeSH Terms:
    Longevity*
    Metabolome*
    Drosophila/*metabolism
    Animals ; Male ; Mass Spectrometry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Amyloid-β peptides slightly affect lifespan or antimicrobial peptide gene expression in Drosophila melanogaster.
    Autorzy:
    Shaposhnikov MV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia.; Institute of Biology of Komi Science Center of Ural Branch of RAS, 167982, Syktyvkar, Russia.
    Zemskaya NV; Institute of Biology of Komi Science Center of Ural Branch of RAS, 167982, Syktyvkar, Russia.
    Koval LА; Institute of Biology of Komi Science Center of Ural Branch of RAS, 167982, Syktyvkar, Russia.
    Minnikhanova NR; Institute of Biology of Komi Science Center of Ural Branch of RAS, 167982, Syktyvkar, Russia.
    Kechko OI; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia.
    Mitkevich VA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia.
    Makarov AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia.
    Moskalev AА; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia. .; Institute of Biology of Komi Science Center of Ural Branch of RAS, 167982, Syktyvkar, Russia. .
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    Źródło:
    BMC genetics [BMC Genet] 2020 Oct 22; Vol. 21 (Suppl 1), pp. 65. Date of Electronic Publication: 2020 Oct 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Longevity*
    Amyloid beta-Peptides/*toxicity
    Drosophila melanogaster/*physiology
    Pore Forming Cytotoxic Proteins/*genetics
    Animals ; Drosophila melanogaster/genetics ; Female ; Locomotion ; Male ; Protein Isoforms
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity.
    Autorzy:
    Moskalev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. .; Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Russia. .; Moscow Institute of Physics and Technology, Dolgoprudny, Russia. .
    Shaposhnikov MV; Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Russia.
    Zemskaya NV; Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Russia.
    Koval LА; Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Russia.
    Schegoleva EV; Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Russia.
    Guvatova ZG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
    Krasnov GS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
    Solovev IA; Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Russia.
    Sheptyakov MA; Moscow Institute of Physics and Technology, Dolgoprudny, Russia.
    Zhavoronkov A; Insilico Medicine, Rockville, USA.
    Kudryavtseva AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
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    Źródło:
    Scientific reports [Sci Rep] 2019 Jun 24; Vol. 9 (1), pp. 9151. Date of Electronic Publication: 2019 Jun 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression Profiling*
    Mutation*
    Drosophila Proteins/*genetics
    Drosophila melanogaster/*genetics
    Drosophila melanogaster/*physiology
    Longevity/*genetics
    Nuclear Proteins/*genetics
    Polycomb Repressive Complex 2/*genetics
    Animals ; Fertility/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-6 z 6

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