Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Zhang, Henggui"" wg kryterium: Autor


Tytuł :
Understanding PITX2-Dependent Atrial Fibrillation Mechanisms through Computational Models.
Autorzy :
Bai J; College of Information Science and Technology, Jinan University, Guangzhou 510632, China.; Auckland Bioengineering Institute, University of Auckland, Auckland 1010, New Zealand.
Lu Y; College of Information Science and Technology, Jinan University, Guangzhou 510632, China.
Zhu Y; College of Information Science and Technology, Jinan University, Guangzhou 510632, China.
Wang H; College of Information Science and Technology, Jinan University, Guangzhou 510632, China.
Yin D; Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin 150000, China.
Zhang H; Biological Physics Group, School of Physics & Astronomy, The University of Manchester, Manchester M13 9PL, UK.
Franco D; Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain.
Zhao J; Auckland Bioengineering Institute, University of Auckland, Auckland 1010, New Zealand.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 19; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease.
Autorzy :
Boyett MR; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK. Electronic address: .
Yanni J; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK.
Tellez J; Northern Molecular Genetics Service, Institute of Genetic Medicine, Biomedicine East Wing, Central Parkway, Newcastle Upon Tyne, NE1 3BZ, UK.
Bucchi A; Department of Biosciences, Università Degli Studi di Milano, Via G. Celoria, 26 20133, Milan, Italy.
Mesirca P; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, France.
Cai X; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK.
Logantha SJRJ; Liverpool Centre for Cardiovascular Science and Department of Cardiovascular and Metabolic Medicine, University of Liverpool, UK.
Wilson C; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK; Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK.
Anderson C; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK.
Ariyaratnam J; Centre for Heart Rhythm Disorders, Royal Adelaide Hospital, Cardiology 4G751-769, University of Adelaide, Port Rd, SA, 5000, Australia.
Stuart L; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK; Manchester Centre for Genomic Medicine and NW Laboratory Genetics Hub, Manchester University NHS Foundation Trust, Manchester, UK.
Nakao S; Department of Biomedical Sciences, College of Life Sciences and Ritsumeikan Global Innovation Research Organization, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga, 525-8577, Japan.
Abd Allah E; Medical Physiology Department, Faculty of Medicine, Assuit University, Assuit, Egypt.
Jones S; Department of Biomedical Sciences, Faculty of Health Sciences, University of Hull, Hull, HU6 7RX, UK.
Lancaster M; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Stephenson R; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Chandler N; Rare & Inherited Disease Laboratory, NHS North Thames Genomic Laboratory Hub, Levels 4-6, Barclay House, Great Ormond Street Hospital for Children NHS Foundation Trust, 37 Queen Square, London, WC1N 3BH, UK.
Smith M; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK.
Bussey C; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland, 1023, New Zealand.
Monfredi O; University of Virginia Health System University Hospital, 1215 Lee St, Charlottesville VA 22903, USA and Laboratory of Cardiovascular Medicine, National Institute on Aging, NIH Biomedical Research Center, Baltimore MD, 21224, USA.
Morris G; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK; Manchester Heart Centre, Manchester University Foundation Trust, Manchester Academic Health Science Centre, Oxford Road, Manchester, M13 9PL, UK.
Billeter R; University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK.
Mangoni ME; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, France.
Zhang H; Biological Physics Group, Department of Physics & Astronomy, University of Manchester, M13 9PL, UK.
Hart G; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK.
D'Souza A; Division of Cardiovascular Sciences, University of Manchester, 46 Grafton Street, Manchester, M13 9NT, UK.
Pokaż więcej
Źródło :
Progress in biophysics and molecular biology [Prog Biophys Mol Biol] 2021 Jun 28. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In silico investigation of pro-arrhythmic effects of azithromycin on the human ventricle.
Autorzy :
Liu Y; Biological Physics Group, School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom.
Zhang R; School of Civil, Aerospace and Mechanical Engineering, University of Bristol, United Kingdom.
Hancox JC; Biological Physics Group, School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom.; School of Physiology, Pharmacology and Neuroscience, Cardiovascular Research Laboratories, School of Medical Sciences, University of Bristol, Bristol, United Kingdom.
Zhang H; Biological Physics Group, School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom.; Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Pokaż więcej
Źródło :
Biochemistry and biophysics reports [Biochem Biophys Rep] 2021 Jun 14; Vol. 27, pp. 101043. Date of Electronic Publication: 2021 Jun 14 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The corrected left ventricular ejection fraction: a potential new measure of ventricular function.
Autorzy :
Rodrigues JCL; NIHR Bristol Cardiovascular Biomedical Research Centre, Cardiac Magnetic Resonance Department, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.; Department of Radiology, Royal United Hospital Bath NHS Foundation Trust, Bath, UK.
Rooms B; Medical School, Faculty of Medicine and Dentistry, University of Bristol, Bristol, UK.
Hyde K; Medical School, Faculty of Medicine and Dentistry, University of Bristol, Bristol, UK.
Rohan S; Medical School, Faculty of Medicine and Dentistry, University of Bristol, Bristol, UK.
Nightingale AK; CardioNomics Research Group, Clinical Research and Imaging Centre, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Paton J; CardioNomics Research Group, Clinical Research and Imaging Centre, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.; Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.
Manghat N; Department of Radiology, Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Bucciarelli-Ducci C; NIHR Bristol Cardiovascular Biomedical Research Centre, Cardiac Magnetic Resonance Department, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Hamilton M; Department of Radiology, Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Zhang H; Biological Physics Group, School of Physics and Astronomy, University of Manchester, Manchester, UK.
MacIver DH; Biological Physics Group, School of Physics and Astronomy, University of Manchester, Manchester, UK. .; Department of Cardiology, Musgrove Park Hospital, Taunton, TA1 5DA, UK. .
Pokaż więcej
Źródło :
The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2021 Jun; Vol. 37 (6), pp. 1987-1997. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate.
Autorzy :
D'Souza A; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom. Electronic address: .
Wang Y; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Anderson C; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Bucchi A; Department of Biosciences, University of Milan, Milan, Italy.
Baruscotti M; Department of Biosciences, University of Milan, Milan, Italy.
Olieslagers S; Department of Cardiology, Maastricht University, Maastricht, The Netherlands.
Mesirca P; Institut de Génomique Fonctionnelle, Université de Montpellie, CNRS, Montpellier, France.
Johnsen AB; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Mastitskaya S; Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Ni H; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Zhang Y; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Black N; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Cox C; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Wegner S; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Bano-Otalora B; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Petit C; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Gill E; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Logantha SJRJ; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom; Liverpool Centre for Cardiovascular Sciences, University of Liverpool, Liverpool, UK.
Dobrzynski H; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Ashton N; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Hart G; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Zhang R; School of Civil, Aerospace and Mechanical Engineering, University of Bristol, Bristol, United Kingdom.
Zhang H; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Cartwright EJ; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Wisloff U; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Mangoni ME; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
da Costa Martins PA; Department of Cardiology, Maastricht University, Maastricht, The Netherlands.
Piggins HD; School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, United Kingdom.
DiFrancesco D; Department of Biosciences, University of Milan, Milan, Italy; IBF-CNR, Milan, Italy.
Boyett MR; Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Pokaż więcej
Źródło :
Heart rhythm [Heart Rhythm] 2021 May; Vol. 18 (5), pp. 801-810. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Physiological Roles of the Rapidly Activated Delayed Rectifier K + Current in Adult Mouse Heart Primary Pacemaker Activity.
Autorzy :
Hu, Wei (AUTHOR)
Clark, Robert B. (AUTHOR)
Giles, Wayne R. (AUTHOR)
Shibata, Erwin (AUTHOR)
Zhang, Henggui (AUTHOR) henggui.zhang@manchester.ac.uk
Delisle, Brian P. (AUTHOR)
Pokaż więcej
Źródło :
International Journal of Molecular Sciences. May2021, Vol. 22 Issue 9, p4761-4761. 1p.
Czasopismo naukowe
Tytuł :
Automatic Detection for Multi-Labeled Cardiac Arrhythmia Based on Frame Blocking Preprocessing and Residual Networks.
Autorzy :
Li Z; Biological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Zhang H; Biological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; Peng Cheng Laboratory, Shenzhen, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Pokaż więcej
Źródło :
Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2021 Mar 19; Vol. 8, pp. 616585. Date of Electronic Publication: 2021 Mar 19 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Reciprocal interaction between IK1 and If in biological pacemakers: A simulation study.
Autorzy :
Li Y; School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.
Wang K; School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.
Li Q; School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.; Peng Cheng Laboratory, Shenzhen, China.
Hancox JC; School of Physiology, Pharmacology and Neuroscience, Medical Sciences Building, University Walk, Bristol, United Kingdom.; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Zhang H; Peng Cheng Laboratory, Shenzhen, China.; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Pokaż więcej
Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 Mar 10; Vol. 17 (3), pp. e1008177. Date of Electronic Publication: 2021 Mar 10 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Electrophysiological Mechanisms Underlying T-Wave Alternans and Their Role in Arrhythmogenesis.
Autorzy :
You T; Key Lab of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Luo C; School of Computer Science and Electronic Engineering, University of Essex, Colchester, United Kingdom.
Zhang K; School of Medicine, Imperial College of London, London, United Kingdom.
Zhang H; Key Lab of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.; Department of Physics and Astronomy, University of Manchester, Manchester, United Kingdom.
Pokaż więcej
Źródło :
Frontiers in physiology [Front Physiol] 2021 Mar 04; Vol. 12, pp. 614946. Date of Electronic Publication: 2021 Mar 04 (Print Publication: 2021).
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Arrhythmogenic Mechanisms in Hypokalaemia: Insights From Pre-clinical Models.
Autorzy :
Tse G; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.; Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.
Li KHC; Faculty of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Cheung CKY; Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Letsas KP; Second Department of Cardiology, Laboratory of Cardiac Electrophysiology, Evangelismos General Hospital of Athens, Athens, Greece.
Bhardwaj A; Division of Cardiology, Department of Internal Medicine, State University of New York at Buffalo, Buffalo, NY, United States.
Sawant AC; Division of Cardiology, Department of Internal Medicine, State University of New York at Buffalo, Buffalo, NY, United States.
Liu T; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
Yan GX; Lankenau Institute for Medical Research and Lankenau Medical Center, Wynnewood, PA, United States.
Zhang H; School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Jeevaratnam K; Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.
Sayed N; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, United States.; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA, United States.
Cheng SH; Department of Biomedical Sciences, College of Veterinary Medicine and Life Science, City University of Hong Kong, Hong Kong, China.; State Key Laboratory of Marine Pollution (SKLMP), City University of Hong Kong, Hong Kong, China.; Department of Materials Science and Engineering, College of Science and Engineering, City University of Hong Kong, Hong Kong, China.
Wong WT; School of Life Sciences, Chinese University of Hong Kong, Hong Kong, China.
Pokaż więcej
Źródło :
Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2021 Feb 03; Vol. 8, pp. 620539. Date of Electronic Publication: 2021 Feb 03 (Print Publication: 2021).
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
In Silico Assessment of Class I Antiarrhythmic Drug Effects on Pitx2 -Induced Atrial Fibrillation: Insights from Populations of Electrophysiological Models of Human Atrial Cells and Tissues.
Autorzy :
Bai, Jieyun (AUTHOR)
Zhu, Yijie (AUTHOR)
Lo, Andy (AUTHOR)
Gao, Meng (AUTHOR)
Lu, Yaosheng (AUTHOR)
Zhao, Jichao (AUTHOR)
Zhang, Henggui (AUTHOR) henggui.zhang@manchester.ac.uk
Wu, Sheng-Nan (AUTHOR)
Pokaż więcej
Źródło :
International Journal of Molecular Sciences. Feb2021, Vol. 22 Issue 3, p1265-1265. 1p.
Czasopismo naukowe
Tytuł :
The Role of CaMKII Overexpression and Oxidation in Atrial Fibrillation-A Simulation Study.
Autorzy :
Wang W; Shenzhen Key Laboratory of Visual Object Detection and Recognition, Harbin Institute of Technology, Shenzhen, China.; Peng Cheng Lab, Shenzhen, China.
Shen W; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Zhang S; Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.
Luo G; Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.
Wang K; Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.
Xu Y; Shenzhen Key Laboratory of Visual Object Detection and Recognition, Harbin Institute of Technology, Shenzhen, China.
Zhang H; Peng Cheng Lab, Shenzhen, China.; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Pokaż więcej
Źródło :
Frontiers in physiology [Front Physiol] 2020 Dec 18; Vol. 11, pp. 607809. Date of Electronic Publication: 2020 Dec 18 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Cardiac Pacemaker Dysfunction Arising From Different Studies of Ion Channel Remodeling in the Aging Rat Heart.
Autorzy :
Alghamdi AM; Biological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; Department of Physics, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia.
Boyett MR; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Hancox JC; Biological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; School of Physiology, Pharmacology and Neuroscience, and Cardiovascular Research Laboratories, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom.
Zhang H; Biological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; Peng Cheng Laboratory, Shenzhen, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Pokaż więcej
Źródło :
Frontiers in physiology [Front Physiol] 2020 Dec 03; Vol. 11, pp. 546508. Date of Electronic Publication: 2020 Dec 03 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Mechanistic Insights Into the Reduced Pacemaking Rate of the Rabbit Sinoatrial Node During Postnatal Development: A Simulation Study.
Autorzy :
Alghamdi AM; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; Department of Physics, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia.
Testrow CP; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Whittaker DG; Department of Mathematics, University of Nottingham, Nottingham, United Kingdom.
Boyett MR; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Hancox JC; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; School of Physiology, Pharmacology and Neuroscience, and Cardiovascular Research Laboratories, School of Medical Sciences, University of Bristol, Bristol, United Kingdom.
Zhang H; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.; Peng Cheng Laboratory, Shenzhen, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Pokaż więcej
Źródło :
Frontiers in physiology [Front Physiol] 2020 Nov 20; Vol. 11, pp. 547577. Date of Electronic Publication: 2020 Nov 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells.
Autorzy :
Fenske S; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 80802, Munich, Germany.
Hennis K; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Rötzer RD; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Brox VF; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Becirovic E; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Scharr A; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Gruner C; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Ziegler T; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 80802, Munich, Germany.; Klinikum Rechts der Isar, TU Munich, 81675, Munich, Germany.
Mehlfeld V; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Brennan J; Department of Biomedical Engineering, George Washington University, Washington, DC, 20052, USA.
Efimov IR; Department of Biomedical Engineering, George Washington University, Washington, DC, 20052, USA.
Pauža AG; Institute of Anatomy, Lithuanian University of Health Sciences, LT, 44307, Kaunas, Lithuania.
Moser M; Max Planck Institute of Biochemistry, Department of Molecular Medicine, 82152, Martinsried, Germany.
Wotjak CT; Max Planck Institute of Psychiatry, Research Group Neuronal Plasticity, 80804, Munich, Germany.; Central Nervous System Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397, Biberach Riß, Germany.
Kupatt C; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 80802, Munich, Germany.; Klinikum Rechts der Isar, TU Munich, 81675, Munich, Germany.
Gönner R; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Zhang R; Department of Aerospace Engineering, University of Bristol, Bristol, BS8 1QU, UK.
Zhang H; Department of Physics and Astronomy, The University of Manchester, Manchester, M13 9PL, UK.
Zong X; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.
Biel M; Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377, Munich, Germany. .
Wahl-Schott C; Hannover Medical School, Institute for Neurophysiology, 30625, Hannover, Germany. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Nov 03; Vol. 11 (1), pp. 5555. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Clocks*/drug effects
Cyclic AMP/*metabolism
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/*metabolism
Sinoatrial Node/*pathology
Action Potentials/drug effects ; Animals ; Arrhythmias, Cardiac/complications ; Arrhythmias, Cardiac/pathology ; Blood Pressure/drug effects ; Bradycardia/complications ; Bradycardia/pathology ; Carbachol/pharmacology ; Electrocardiography ; Female ; HEK293 Cells ; Heart/drug effects ; Heart/physiopathology ; Heart Rate/drug effects ; Humans ; Mice, Inbred C57BL ; Protein Subunits/metabolism ; Reproducibility of Results ; Sinoatrial Node/physiopathology ; Vagus Nerve/drug effects ; Vagus Nerve/physiopathology
Czasopismo naukowe
Tytuł :
Populations of in silico myocytes and tissues reveal synergy of multiatrial-predominant K -current block in atrial fibrillation.
Autorzy :
Ni H; Department of Pharmacology, University of California, Davis, CA, USA.
Fogli Iseppe A; Department of Pharmacology, University of California, Davis, CA, USA.
Giles WR; Faculties of Kinesiology and Medicine, University of Calgary, Calgary, Alberta, Canada.
Narayan SM; Division of Cardiology, Cardiovascular Institute, Stanford University, Stanford, CA, USA.
Zhang H; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, UK.
Edwards AG; Department of Pharmacology, University of California, Davis, CA, USA.
Morotti S; Department of Pharmacology, University of California, Davis, CA, USA.
Grandi E; Department of Pharmacology, University of California, Davis, CA, USA.
Pokaż więcej
Źródło :
British journal of pharmacology [Br J Pharmacol] 2020 Oct; Vol. 177 (19), pp. 4497-4515. Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Atrial Fibrillation*/drug therapy
Action Potentials ; Anti-Arrhythmia Agents/pharmacology ; Anti-Arrhythmia Agents/therapeutic use ; Computer Simulation ; Heart Atria ; Humans ; Myocytes, Cardiac
Czasopismo naukowe
Tytuł :
FWAVina: A novel optimization algorithm for protein-ligand docking based on the fireworks algorithm.
Autorzy :
Li J; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research and School of Medical Information and Engineering, Southwest Medical University, Luzhou 646000, China; College of Computer and Information Science, Southwest University, Chongqing 400715, China.
Song Y; Luzhou High School, Luzhou 646000, China.
Li F; Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Science, Tsinghua University, Beijing 100084, China.
Zhang H; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research and School of Medical Information and Engineering, Southwest Medical University, Luzhou 646000, China; Biological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Liu W; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research and School of Medical Information and Engineering, Southwest Medical University, Luzhou 646000, China. Electronic address: .
Pokaż więcej
Źródło :
Computational biology and chemistry [Comput Biol Chem] 2020 Oct; Vol. 88, pp. 107363. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Molecular Docking Simulation*
Proteins/*chemistry
Ligands
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies