Autor: "Zhang, P." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Hydrogen sulphide attenuates neuronal apoptosis of substantia nigra by re-establishing autophagic flux via promoting leptin signalling in a 6-hydroxydopamine rat model of Parkinson's disease.
Autorzy:: Jiang W; The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Zou W; The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Hu M; The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Tian Q; Hengyang Key Laboratory of Neurodegeneration and Cognitive Impairment, Institute of Neuroscience, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Xiao F; The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Li M; The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Zhang P; The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Chen YJ; The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Jiang JM; The First Affiliated Hospital, Institute of Neurology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.; Pokaż więcej
Źródło:: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Jan; Vol. 49 (1), pp. 122-133. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Autophagy/*drug effects
Hydrogen Sulfide/*therapeutic use
Leptin/*metabolism
Neuroprotective Agents/*therapeutic use
Parkinsonian Disorders/*drug therapy
Substantia Nigra/*drug effects
Animals ; Autophagosomes/drug effects ; Hydrogen Sulfide/pharmacology ; Male ; Microscopy, Electron, Transmission ; Neuroprotective Agents/pharmacology ; Oxidopamine/pharmacology ; Parkinsonian Disorders/pathology ; Rats ; Rats, Sprague-Dawley ; Substantia Nigra/metabolism ; Substantia Nigra/pathology

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Skocz do pozycji: 2.

Tytuł:: Mig-6 could inhibit cell proliferation and induce apoptosis in esophageal squamous cell carcinoma.
Autorzy:: Cui Y; Department of Cardiothoracic Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Kang Y; Department of Cardiothoracic Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Zhang P; Department of Cardiothoracic Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Wang Y; Department of Cardiothoracic Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Yang Z; Department of Cardiothoracic Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Lu C; Department of Cardiothoracic Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Zhang P; Department of Cardiothoracic Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.; Pokaż więcej
Źródło:: Thoracic cancer [Thorac Cancer] 2022 Jan; Vol. 13 (1), pp. 54-60. Date of Electronic Publication: 2021 Nov 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adaptor Proteins, Signal Transducing/*genetics
Apoptosis/*genetics
Cell Proliferation/*genetics
Esophageal Neoplasms/*genetics
Esophageal Squamous Cell Carcinoma/*genetics
Tumor Suppressor Proteins/*genetics
Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/genetics ; Humans

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Skocz do pozycji: 3.

Tytuł:: Human Schlafen 5 Inhibits Proliferation and Promotes Apoptosis in Lung Adenocarcinoma via the PTEN/PI3K/AKT/mTOR Pathway.
Autorzy:: Gu X; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Zhou L; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.
Chen L; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.; Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Pan H; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Zhao R; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.; Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Guang W; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Wan G; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Zhang P; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Liu D; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.
Deng LL; Department of Oncology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Zhao W; Qiqihar Medical University, Qiqihar, Heilongjiang, China.
Lu C; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Mar 23; Vol. 2021, pp. 6628682. Date of Electronic Publication: 2021 Mar 23 (Print Publication: 2021).
Typ publikacji:: Journal Article; Retracted Publication
MeSH Terms:: Apoptosis*
Adenocarcinoma of Lung/*pathology
Cell Cycle Proteins/*metabolism
Lung Neoplasms/*pathology
PTEN Phosphohydrolase/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
TOR Serine-Threonine Kinases/*metabolism
A549 Cells ; Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/metabolism ; Animals ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Glycogen Synthase Kinase 3 beta/metabolism ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Mice, Nude ; Phosphorylation ; Signal Transduction ; Transcription, Genetic ; Mice

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Skocz do pozycji: 4.

Tytuł:: Berberine and Cisplatin Exhibit Synergistic Anticancer Effects on Osteosarcoma MG-63 Cells by Inhibiting the MAPK Pathway.
Autorzy:: Gao X; Department of Pharmacology, School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Zhang C; Department of Pharmacology, School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Wang Y; Department of Pharmacology, School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Zhang P; Department of Pharmacology, School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Zhang J; Department of Pharmacology, School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Hong T; Department of Pharmacology, School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Mar 17; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 17.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Apoptosis/*drug effects
Berberine/*pharmacology
Cisplatin/*pharmacology
MAP Kinase Signaling System/*drug effects
Osteosarcoma/*drug therapy
Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cyclin D1/metabolism ; Cyclin-Dependent Kinase 4/metabolism ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 5.

Tytuł:: Neuronal Apoptosis Preventive Potential of Sophocarpine via Suppression of Aβ-Accumulation and Down-Regulation of Inflammatory Response.
Autorzy:: Zhu X; Changchun University of Chinese Medicine, 130117, Changchun, Jilin, China.
Gu Z; Neurology, Third Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine, 130117, Changchun, Jilin, China.
Yu Y; Neurology, Songyuan Central Hospital, 138000, Songyuan, Jilin, China.
Yang W; GCP Office, Affiliated Hospital of Changchun University of Traditional Chinese Medicine, 130021, Changchun, Jilin, China.
Li M; Neurology, Third Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine, 130117, Changchun, Jilin, China.
Li Y; Ultrasound Electrophysiological Diagnostic Center, Third Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine, 130117, Changchun, Jilin, China.
Zhang P; Changchun University of Chinese Medicine, 130117, Changchun, Jilin, China.
Wang J; Changchun University of Chinese Medicine, 130117, Changchun, Jilin, China.
Zhao J; Neurology, Affiliated Hospital of Changchun University of Traditional Chinese Medicine, 130021, Changchun, Jilin, China. .; Pokaż więcej
Źródło:: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2021 Mar; Vol. 497 (1), pp. 116-122. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids/*pharmacology
Amyloid beta-Peptides/*metabolism
Apoptosis/*drug effects
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Animals ; Cyclooxygenase 2/metabolism ; Inflammation/metabolism ; Inflammation/pathology ; NF-kappa B/metabolism ; Neurons/cytology ; Neurons/metabolism ; Neurons/pathology ; PC12 Cells ; Rats ; Signal Transduction/drug effects

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Skocz do pozycji: 6.

Tytuł:: lncRNA MALAT1 Regulates Mouse Granulosa Cell Apoptosis and 17 β -Estradiol Synthesis via Regulating miR-205/CREB1 Axis.
Autorzy:: Sun L; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Zhang P; Institute of Animal Biotechnology, Jilin Academy of Agricultural Sciences, Changchan 130033, China.
Lu W; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Feb 17; Vol. 2021, pp. 6671814. Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Signal Transduction*
Cyclic AMP Response Element-Binding Protein/*metabolism
Estradiol/*biosynthesis
Granulosa Cells/*metabolism
MicroRNAs/*metabolism
RNA, Long Noncoding/*metabolism
Animals ; Cyclic AMP Response Element-Binding Protein/genetics ; Estradiol/genetics ; Female ; Mice ; MicroRNAs/genetics ; RNA, Long Noncoding/genetics

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Skocz do pozycji: 7.

Tytuł:: MZF1 alleviates oxidative stress and apoptosis induced by rotenone in SH-SY5Y cells by promoting RBM3 transcription.
Autorzy:: Zhang J; Department of Neurology, Jiangxi Provincial People's Hospital, China.
Chai W; Department of Neurology, Jiangxi Provincial People's Hospital, China.
Xiang Z; Department of Neurology, Jiangxi Provincial People's Hospital, China.
Zhou X; Department of Neurology, Jiangxi Provincial People's Hospital, China.
Zhang P; Department of Neurology, Jiangxi Provincial People's Hospital, China.; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2021; Vol. 46 (10), pp. 477-486.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Kruppel-Like Transcription Factors*/metabolism
Oxidative Stress*
RNA-Binding Proteins*/genetics
Rotenone*/toxicity
Cell Line, Tumor ; Humans ; Neurons

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Skocz do pozycji: 8.

Tytuł:: Reactive oxygen species, not Ca , mediates methotrexate-induced autophagy and apoptosis in spermatocyte cell line.
Autorzy:: Xiong S; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.
Song D; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.
Xiang Y; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.
Li Y; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.
Zhong Y; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.
Li H; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.
Zhang P; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.
Zhou W; Medical School, Institute of Reproductive Medicine, Nantong University, Nantong, China.
Zeng X; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.; Medical School, Institute of Reproductive Medicine, Nantong University, Nantong, China.
Zhang X; Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, China.; Medical School, Institute of Reproductive Medicine, Nantong University, Nantong, China.; Pokaż więcej
Źródło:: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2020 Feb; Vol. 126 (2), pp. 144-152. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Methotrexate/*toxicity
Reactive Oxygen Species/*metabolism
Spermatocytes/*drug effects
Animals ; Antimetabolites, Antineoplastic/toxicity ; Autophagy/drug effects ; Calcium/metabolism ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Male ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Signal Transduction/drug effects ; Spermatocytes/pathology

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Skocz do pozycji: 9.

Tytuł:: TRIM21-SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis.
Autorzy:: Zhang P; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China.
Li X; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China.
He Q; Max-Planck Center for Tissue Stem cell Research and Regenerative Medicine, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, 510530, People's Republic of China.
Zhang L; Department of Molecular Diagnostics, Sun Yat-sen University Cancer Center, Guangzhou, China.
Song K; FireGen Biomedicals Co., LTD, Jiangsu, 215300, China.
Yang X; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China.
He Q; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China.
Wang Y; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China.
Hong X; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China.
Ma J; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China. .
Liu N; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangdong, 510060, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 Jan 31; Vol. 27 (1), pp. 30. Date of Electronic Publication: 2020 Jan 31.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*/radiation effects
Nasopharyngeal Carcinoma/*metabolism
Ribonucleoproteins/*genetics
Serpins/*genetics
Tumor Suppressor Protein p53/*genetics
Cell Line, Tumor ; Humans ; Ribonucleoproteins/metabolism ; Serpins/metabolism ; Tumor Suppressor Protein p53/metabolism

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Skocz do pozycji: 10.

Tytuł:: Psoralen induces hepatic toxicity through PERK and ATF6 related ER stress pathways in HepG2 cells.
Autorzy:: Yu Y; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.; Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin, China.
Yu R; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Men W; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhang P; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhang Y; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.; Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin, China.
Song L; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.; Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin, China.
Zhou K; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.; Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin, China.; Key Laboratory of Formula of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Ministry of Education, Tianjin, China.; Pokaż więcej
Źródło:: Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Jan; Vol. 30 (1), pp. 39-47. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji:: Journal Article
MeSH Terms:: Activating Transcription Factor 6/*metabolism
Apoptosis/*drug effects
Chemical and Drug Induced Liver Injury/*etiology
Endoplasmic Reticulum Stress/*drug effects
Ficusin/*toxicity
Liver/*drug effects
eIF-2 Kinase/*metabolism
Activating Transcription Factor 4/metabolism ; Chemical and Drug Induced Liver Injury/enzymology ; Chemical and Drug Induced Liver Injury/pathology ; Endoplasmic Reticulum Chaperone BiP ; Eukaryotic Initiation Factor-2/metabolism ; Hep G2 Cells ; Humans ; Liver/enzymology ; Liver/pathology ; Signal Transduction ; Transcription Factor CHOP/metabolism ; Unfolded Protein Response/drug effects

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Skocz do pozycji: 11.

Tytuł:: 1,25‑Dihydroxyvitamin D3 enhances the susceptibility of anaplastic thyroid cancer cells to adriamycin‑induced apoptosis by increasing the generation of reactive oxygen species.
Autorzy:: Zhang T; Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
He L; Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
Sun W; Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
Qin Y; Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
Zhang P; Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
Zhang H; Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Sep; Vol. 20 (3), pp. 2641-2648. Date of Electronic Publication: 2019 Jul 25.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Calcitriol/*pharmacology
Doxorubicin/*pharmacology
Reactive Oxygen Species/*metabolism
Thyroid Carcinoma, Anaplastic/*etiology
Thyroid Carcinoma, Anaplastic/*metabolism
Biomarkers ; Caspase 3/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Enzyme Activation/drug effects ; Humans ; Thyroid Carcinoma, Anaplastic/pathology

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Skocz do pozycji: 12.

Tytuł:: LukS-PV induces apoptosis in acute myeloid leukemia cells mediated by C5a receptor.
Autorzy:: Zhang P; School of Medicine, Shandong University, Jinan, Shandong, China.
Yu WW; Department of Clinical Laboratory, Anhui Provincial Hospital, Hefei, Anhui, China.
Peng J; Department of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Xu LF; Department of Clinical Laboratory, Anhui Provincial Hospital, Hefei, Anhui, China.
Zhao CC; Department of Clinical Laboratory, Anhui Provincial Hospital of Infectious Disease, Hefei, Anhui, China.
Chang WJ; Department of Clinical Laboratory, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Ma XL; Department of Clinical Laboratory, Anhui Provincial Hospital, Hefei, Anhui, China.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2019 May; Vol. 8 (5), pp. 2474-2483. Date of Electronic Publication: 2019 Apr 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Bacterial Toxins/*pharmacology
Exotoxins/*pharmacology
Leukemia, Myeloid, Acute/*metabolism
Leukocidins/*pharmacology
Receptor, Anaphylatoxin C5a/*metabolism
Bacterial Toxins/metabolism ; Cell Line, Tumor ; Exotoxins/metabolism ; Flow Cytometry ; Humans ; Leukocidins/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Protein Binding ; Receptor, Anaphylatoxin C5a/antagonists & inhibitors ; Recombinant Proteins

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Skocz do pozycji: 13.

Tytuł:: Ivermectin induces cell cycle arrest and apoptosis of HeLa cells via mitochondrial pathway.
Autorzy:: Zhang P; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, China.
Zhang Y; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, China.
Liu K; Shandong Key Laboratory of Chemical Medicine, Shandong Academy of Pharmaceutical Sciences, Jinan, China.
Liu B; Vegetable Technical Extension Station Qingpu District Shanghai, Shanghai, China.
Xu W; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, China.
Gao J; College of Life and Environmental Sciences, Shanghai Normal University, Shanghai, China.
Ding L; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, China.
Tao L; Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, China.; Pokaż więcej
Źródło:: Cell proliferation [Cell Prolif] 2019 Mar; Vol. 52 (2), pp. e12543. Date of Electronic Publication: 2018 Dec 04.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Antiparasitic Agents/*pharmacology
Apoptosis/*drug effects
Cell Cycle Checkpoints/*drug effects
Ivermectin/*pharmacology
Mitochondria/*drug effects
Uterine Cervical Neoplasms/*drug therapy
Cell Survival/drug effects ; Female ; HeLa Cells ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/metabolism ; Mitochondria/pathology ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/pathology

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Skocz do pozycji: 14.

Tytuł:: Endoplasmic reticulum stress associated apoptosis as a novel mechanism in indoxyl sulfate‑induced cardiomyocyte toxicity.
Autorzy:: Tan X; Shanghai Key Laboratory of Kidney and Blood Purification, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Cao XS; Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Zhang P; Shanghai Key Laboratory of Kidney and Blood Purification, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Xiang FF; Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Teng J; Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Zou JZ; Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Ding XQ; Shanghai Key Laboratory of Kidney and Blood Purification, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Dec; Vol. 18 (6), pp. 5117-5122. Date of Electronic Publication: 2018 Sep 20.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Endoplasmic Reticulum Stress*
Indican/*pharmacology
Myocytes, Cardiac/*drug effects
Myocytes, Cardiac/*metabolism
Animals ; Biomarkers ; Cell Line ; Flow Cytometry ; MAP Kinase Kinase 4/metabolism ; Signal Transduction

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Skocz do pozycji: 15.

Tytuł:: Calcitonin gene‑related peptide reduces Porphyromonas gingivalis LPS‑induced TNF‑α release and apoptosis in osteoblasts.
Autorzy:: Zhou Y; Department of Oral and Maxillofacial Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Zhang H; Department of Oral and Maxillofacial Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Zhang G; Department of Oral and Maxillofacial Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
He Y; Department of Stomatology, General Hospital of Chengdu Military Region of PLA, Chengdu, Sichuan 610083, P.R. China.
Zhang P; Department of Oral and Maxillofacial Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Sun Z; Jiebao Biotechnology, Wuhan, Hubei 430012, P.R. China.
Gao Y; Department of Oral and Maxillofacial Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Tan Y; Department of Oral and Maxillofacial Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Feb; Vol. 17 (2), pp. 3246-3254. Date of Electronic Publication: 2017 Dec 06.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Calcitonin Gene-Related Peptide/*pharmacology
Lipopolysaccharides/*toxicity
Porphyromonas gingivalis/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cells, Cultured ; Cytokines/analysis ; Enzyme-Linked Immunosorbent Assay ; Mice ; Mice, Inbred BALB C ; Osteoblasts/cytology ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Tumor Necrosis Factor-alpha/analysis

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Skocz do pozycji: 16.

Tytuł:: Curcumin synergizes with 5-fluorouracil by impairing AMPK/ULK1-dependent autophagy, AKT activity and enhancing apoptosis in colon cancer cells with tumor growth inhibition in xenograft mice.
Autorzy:: Zhang P; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China.
Lai ZL; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China.
Chen HF; Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China.
Zhang M; Department of Clinical Laboratory, Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai, 201508, China.
Wang A; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Jia T; INSERM-UGA U1209, CNRS UMR5309, Institute for Advanced Biosciences, F-38700, La Tronche, France.
Sun WQ; Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China.
Zhu XM; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China.
Chen XF; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China. dr_.
Zhao Z; Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062, China. .
Zhang J; Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China. .; Department of Clinical Laboratory, Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai, 201508, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2017 Dec 22; Vol. 36 (1), pp. 190. Date of Electronic Publication: 2017 Dec 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication
MeSH Terms:: Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Apoptosis/*drug effects
Autophagy/*drug effects
Colonic Neoplasms/*pathology
Drug Resistance, Neoplasm/*drug effects
AMP-Activated Protein Kinase Kinases ; Animals ; Autophagy-Related Protein-1 Homolog/metabolism ; Cell Line, Tumor ; Curcumin/pharmacology ; Drug Synergism ; Fluorouracil/pharmacology ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Protein Kinases/metabolism ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 17.

Tytuł:: Leukemia-associated gene MLAA-34 reduces arsenic trioxide-induced apoptosis in HeLa cells via activation of the Wnt/β-catenin signaling pathway.
Autorzy:: Zhang P; Department of Hematology, Second Affiliated Hospital, Xi' an Jiaotong University, Xi'an, Shaanxi, China.
Zhao X; Department of Histology&Embryology, Xi'an Medical College, Xi'an, Shaanxi, China.
Zhang W; Shaanxi Blood Center, Xi'an, Shaanxi, China.
He A; Department of Hematology, Second Affiliated Hospital, Xi' an Jiaotong University, Xi'an, Shaanxi, China.
Lei B; Department of Hematology, Second Affiliated Hospital, Xi' an Jiaotong University, Xi'an, Shaanxi, China.
Zhang W; Department of Hematology, Second Affiliated Hospital, Xi' an Jiaotong University, Xi'an, Shaanxi, China.
Chen Y; Department of Hematology, Second Affiliated Hospital, Xi' an Jiaotong University, Xi'an, Shaanxi, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Oct 23; Vol. 12 (10), pp. e0186868. Date of Electronic Publication: 2017 Oct 23 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Antigens, Neoplasm/*genetics
Apoptosis/*drug effects
Apoptosis Regulatory Proteins/*genetics
Oxides/*toxicity
Wnt Proteins/*metabolism
beta Catenin/*metabolism
Arsenic Trioxide ; Arsenicals ; Blotting, Western ; HeLa Cells ; Humans

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Skocz do pozycji: 18.

Tytuł:: Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells.
Autorzy:: Wu Y; Department of Dermatology, Xiangyang Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.
Zhang P; Department of Radiotherapy, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China.
Yang H; Department of Dermatology, Xiangyang Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.
Ge Y; Department of Clinical Laboratory, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang, Hubei 441000, P.R. China.
Xin Y; Department of Radiotherapy, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 Jul; Vol. 16 (1), pp. 539-546. Date of Electronic Publication: 2017 May 31.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Curcumin/*analogs & derivatives
Antineoplastic Agents/chemistry ; Caspase 3/metabolism ; Caspase 9/metabolism ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Curcumin/chemistry ; Curcumin/pharmacology ; Cytochromes c/genetics ; Cytochromes c/metabolism ; Diarylheptanoids ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Skin Neoplasms/metabolism ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 19.

Tytuł:: Tamoxifen Attenuates Lipopolysaccharide/Galactosamine-induced Acute Liver Failure by Antagonizing Hepatic Inflammation and Apoptosis.
Autorzy:: Zhang P; a Medical School of Jinggangshan University , Ji'an , Jiangxi , China.
Zhang M; b Longgang District People's Hospital , Shenzhen , Guangdong , China.
Wan M; a Medical School of Jinggangshan University , Ji'an , Jiangxi , China.
Huang X; a Medical School of Jinggangshan University , Ji'an , Jiangxi , China.
Jiang Y; a Medical School of Jinggangshan University , Ji'an , Jiangxi , China.
Xu S; a Medical School of Jinggangshan University , Ji'an , Jiangxi , China.
Luo M; a Medical School of Jinggangshan University , Ji'an , Jiangxi , China.; Pokaż więcej
Źródło:: Immunological investigations [Immunol Invest] 2017 Apr; Vol. 46 (3), pp. 284-294. Date of Electronic Publication: 2016 Dec 14.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Chemical and Drug Induced Liver Injury/*drug therapy
Liver/*drug effects
Liver Failure, Acute/*drug therapy
Tamoxifen/*therapeutic use
Animals ; Caspase 3/metabolism ; Galactosamine/immunology ; Humans ; Interleukin-1beta/blood ; Lipopolysaccharides/immunology ; Liver/immunology ; Liver/pathology ; Liver Failure, Acute/chemically induced ; Mice ; Mice, Inbred BALB C ; Transaminases/blood ; Tumor Necrosis Factor-alpha/blood

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Skocz do pozycji: 20.

Tytuł:: Calcium and oxidative stress mediate perillaldehyde-induced apoptosis in Candida albicans.
Autorzy:: Tian H; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China.
Qu S; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China.
Wang Y; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China.
Lu Z; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China.
Zhang M; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China.
Gan Y; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China.
Zhang P; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China. .
Tian J; College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China. .; Key Lab for New Drug Research of TCM and Shenzhen Branch, State R&D Centre for Viro-Biotech, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong, People's Republic of China. .; Pokaż więcej
Źródło:: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2017 Apr; Vol. 101 (8), pp. 3335-3345. Date of Electronic Publication: 2017 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Oxidative Stress*
Calcium/*metabolism
Candida albicans/*drug effects
Monoterpenes/*pharmacology
Candida albicans/physiology ; Cytochromes c/metabolism ; DNA Fragmentation/drug effects ; Flow Cytometry ; Microbial Sensitivity Tests ; Microscopy, Fluorescence ; Reactive Oxygen Species/metabolism

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