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Wyszukujesz frazę ""Zhang, W."" wg kryterium: Autor


Tytuł:
Identification of potential cell death-related biomarkers for diagnosis and treatment of osteoporosis.
Autorzy:
Li M; Department of Joint and Sports Medicine, Weifang Sunshine Union Hospital, Weifang, Shandong Province, 261000, China.
Wang X; Department of endocrinology, Weifang Sunshine Union Hospital, Weifang, Shandong Province, 261000, China.
Guo M; Department of Joint and Sports Medicine, Weifang Sunshine Union Hospital, Weifang, Shandong Province, 261000, China.
Zhang W; Department of Joint and Sports Medicine, Weifang Sunshine Union Hospital, Weifang, Shandong Province, 261000, China.
Li T; Department of Joint and Sports Medicine, Weifang Sunshine Union Hospital, Weifang, Shandong Province, 261000, China.
Zheng J; Department of spine 1, Weifang Sunshine Union Hospital, No. 9000, Yingqian Street, High-tech Zone, Weifang, Shandong Province, 261000, China. .
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Źródło:
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2024 Mar 25; Vol. 25 (1), pp. 235. Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Machine Learning*
Humans ; Cell Death/genetics ; Biomarkers ; Databases, Factual
Czasopismo naukowe
Tytuł:
Cuproptosis-related gene SLC31A1: prognosis values and potential biological functions in cancer.
Autorzy:
Qi Y; Clinical School of Obstetrics and Gynecology Center, Tianjin Medical University, Tianjin, China.; Department of Gynecological Oncology, Tianjin Central Hospital Gynecology Obstetrics, No. 156, Nansanma Road, Nankai District, Tianjin, 300000, China.
Yao Q; Department of Gynecological Oncology, Tianjin Central Hospital Gynecology Obstetrics, No. 156, Nansanma Road, Nankai District, Tianjin, 300000, China.; Nankai University School of Medicine, Nankai University, Tianjin, China.
Li X; Department of Gynecological Oncology, Tianjin Central Hospital Gynecology Obstetrics, No. 156, Nansanma Road, Nankai District, Tianjin, 300000, China.; Nankai University School of Medicine, Nankai University, Tianjin, China.
Li X; Clinical School of Obstetrics and Gynecology Center, Tianjin Medical University, Tianjin, China.; Department of Gynecological Oncology, Tianjin Central Hospital Gynecology Obstetrics, No. 156, Nansanma Road, Nankai District, Tianjin, 300000, China.
Zhang W; Department of Gynecological Oncology, Tianjin Central Hospital Gynecology Obstetrics, No. 156, Nansanma Road, Nankai District, Tianjin, 300000, China. .
Qu P; Clinical School of Obstetrics and Gynecology Center, Tianjin Medical University, Tianjin, China. .; Department of Gynecological Oncology, Tianjin Central Hospital Gynecology Obstetrics, No. 156, Nansanma Road, Nankai District, Tianjin, 300000, China. .; Nankai University School of Medicine, Nankai University, Tianjin, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 18; Vol. 13 (1), pp. 17790. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*
Kidney Neoplasms*
Liver Neoplasms*
Lung Neoplasms*
Apoptosis*
Humans ; Copper ; Copper Transporter 1 ; Prognosis
Czasopismo naukowe
Tytuł:
Downregulation of BIRC2 hinders the progression of rheumatoid arthritis through regulating TRADD.
Autorzy:
Rao Y; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Xu S; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Lu T; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Wang Y; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Liu M; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Zhang W; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Oct; Vol. 11 (10), pp. e978.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/genetics
Arthritis, Rheumatoid*/genetics
Arthritis, Rheumatoid*/metabolism
Humans ; Down-Regulation ; Lipopolysaccharides/pharmacology ; Signal Transduction ; Inflammation ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Inhibitor of Apoptosis Proteins/genetics ; Inhibitor of Apoptosis Proteins/metabolism
Czasopismo naukowe
Tytuł:
The therapeutic and prognostic role of cuproptosis-related genes in triple negative breast cancer.
Autorzy:
Shi B; Color Ultrasound Room, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
Zhang W; Medical Engineering Center, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
Wang T; Department of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
Cui Z; Department of Urology Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei, China. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 May 31; Vol. 24 (1), pp. 223. Date of Electronic Publication: 2023 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Apoptosis*
Humans ; Dasatinib ; Docetaxel ; Mutation ; Prognosis ; Tumor Microenvironment ; Copper
Czasopismo naukowe
Tytuł:
Comprehensive analysis of a cuproptosis-related ceRNA network implicates a potential endocrine therapy resistance mechanism in ER-positive breast cancer.
Autorzy:
Zhang D; Oncology Department, China Academy of Chinese Medical Sciences Guang'anmen Hospital, Beijing, China.
Lu W; Oncology Department, China Academy of Chinese Medical Sciences Guang'anmen Hospital, Beijing, China. lu_.
Zhuo Z; Oncology Department, China Academy of Chinese Medical Sciences Guang'anmen Hospital, Beijing, China.
Wang Y; Oncology Department, China Academy of Chinese Medical Sciences Guang'anmen Hospital, Beijing, China.
Zhang W; Oncology Department, China Academy of Chinese Medical Sciences Guang'anmen Hospital, Beijing, China.
Zhang M; Oncology Department, China Academy of Chinese Medical Sciences Guang'anmen Hospital, Beijing, China.
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 May 05; Vol. 16 (1), pp. 96. Date of Electronic Publication: 2023 May 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MicroRNAs*/genetics
RNA, Long Noncoding*/genetics
Apoptosis*
Humans ; Adjuvants, Immunologic ; Combined Modality Therapy ; Neoplasm Recurrence, Local ; Tumor Microenvironment ; Copper
Czasopismo naukowe
Tytuł:
A Cuproptosis-Related lncRNAs Signature Could Accurately Predict Prognosis in Patients with Clear Cell Renal Cell Carcinoma.
Autorzy:
Zhang W; Department of Urology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Wang H; Department of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Wang W; Department of Urology, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Xue H; Department of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Qiao M; Department of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Song L; Department of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Wang S; Department of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Ren Z; Department of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Ma Z; Department of Urology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
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Źródło:
Analytical cellular pathology (Amsterdam) [Anal Cell Pathol (Amst)] 2022 Dec 22; Vol. 2022, pp. 4673514. Date of Electronic Publication: 2022 Dec 22 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/genetics
Kidney Neoplasms*/genetics
RNA, Long Noncoding*/genetics
Apoptosis*
Humans ; Cell Death ; Tumor Microenvironment ; Copper
Czasopismo naukowe
Tytuł:
A novel cuproptosis-related immune checkpoint gene signature identification and experimental validation in hepatocellular carcinoma.
Autorzy:
Xie Y; Laboratory of Basic Medicine, General Hospital of Northern Theatre Command, Shenyang, 110016, Liaoning, China.
Zhang W; Department of Hepatobiliary Surgery, General Hospital of Northern Theatre Command, Shenyang, 110016, Liaoning, China.
Sun J; Laboratory of Basic Medicine, General Hospital of Northern Theatre Command, Shenyang, 110016, Liaoning, China.
Sun L; Laboratory of Basic Medicine, General Hospital of Northern Theatre Command, Shenyang, 110016, Liaoning, China.
Meng F; Laboratory of Basic Medicine, General Hospital of Northern Theatre Command, Shenyang, 110016, Liaoning, China.
Yu H; Laboratory of Basic Medicine, General Hospital of Northern Theatre Command, Shenyang, 110016, Liaoning, China. .
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 02; Vol. 12 (1), pp. 18514. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Apoptosis*
Humans ; Biomarkers, Tumor/metabolism ; Copper ; Prognosis
Czasopismo naukowe
Tytuł:
iPCD: A Comprehensive Data Resource of Regulatory Proteins in Programmed Cell Death.
Autorzy:
Tang D; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Han C; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Lin S; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Tan X; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Zhang W; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Peng D; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Wang C; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Xue Y; Key Laboratory of Molecular Biophysics of Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
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Źródło:
Cells [Cells] 2022 Jun 24; Vol. 11 (13). Date of Electronic Publication: 2022 Jun 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/genetics
Apoptosis Regulatory Proteins*/metabolism
Eukaryota/metabolism ; Eukaryotic Cells/metabolism ; Humans ; Protein Processing, Post-Translational ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Ginsenoside Rh2 stimulates the production of mitochondrial reactive oxygen species and induces apoptosis of cervical cancer cells by inhibiting mitochondrial electron transfer chain complex.
Autorzy:
Liu Y; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Yu S; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Xing X; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Qiao J; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Yin Y; GeneScience Pharmaceuticals Co., Ltd., Changchun, Jilin 130012, P.R. China.
Wang J; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Liu M; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Zhang W; Scientific Research Department, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 Dec; Vol. 24 (6). Date of Electronic Publication: 2021 Oct 29.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Ginsenosides/*metabolism
Mitochondria/*metabolism
Reactive Oxygen Species/*metabolism
Uterine Cervical Neoplasms/*metabolism
Cell Survival ; Female ; Ginsenosides/chemistry ; Ginsenosides/genetics ; HeLa Cells ; Humans ; Membrane Potential, Mitochondrial ; Mitochondrial Membranes/metabolism ; Molecular Docking Simulation ; Oxidative Phosphorylation
Czasopismo naukowe
Tytuł:
MiR-20a-5p overexpression prevented diabetic cardiomyopathy via inhibition of cardiomyocyte apoptosis, hypertrophy, fibrosis and JNK/NF-κB signalling pathway.
Autorzy:
Liu X; Department of Cardiology, The Second Hospital of Hebei Medical University, No. 215, Heping West Road, Shijiazhuang 050000, China.; The Third Department of Cardiology, Cangzhou Central Hospital, No.16, Xinhua West Road, Cangzhou 061000, China.
Guo B; Department of Cardiology, The Second Hospital of Hebei Medical University, No. 215, Heping West Road, Shijiazhuang 050000, China.
Zhang W; The Third Department of Cardiology, Cangzhou Central Hospital, No.16, Xinhua West Road, Cangzhou 061000, China.
Ma B; The Third Department of Cardiology, Cangzhou Central Hospital, No.16, Xinhua West Road, Cangzhou 061000, China.
Li Y; Department of Cardiology, The Second Hospital of Hebei Medical University, No. 215, Heping West Road, Shijiazhuang 050000, China.
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Źródło:
Journal of biochemistry [J Biochem] 2021 Oct 12; Vol. 170 (3), pp. 349-362.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Diabetes Mellitus, Experimental/*metabolism
Diabetic Cardiomyopathies/*metabolism
MicroRNAs/*metabolism
Myocytes, Cardiac/*metabolism
Animals ; Blood Glucose/metabolism ; Diabetes Mellitus, Experimental/pathology ; Diabetic Cardiomyopathies/pathology ; Diabetic Cardiomyopathies/prevention & control ; Fibrosis/metabolism ; Hypertrophy/metabolism ; Inflammation/metabolism ; MAP Kinase Signaling System ; Male ; MicroRNAs/genetics ; Myocytes, Cardiac/drug effects ; NF-kappa B/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; rho-Associated Kinases/genetics ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Tytuł:
MicroRNA‑93 inhibits the apoptosis and inflammatory response of tubular epithelial cells via the PTEN/AKT/mTOR pathway in acute kidney injury.
Autorzy:
Zhan Y; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China.
Zhu M; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China.
Liu S; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China.
Lu J; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China.
Ni Z; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China.
Cai H; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China.
Zhang W; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 Sep; Vol. 24 (3). Date of Electronic Publication: 2021 Jul 23.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Kidney Injury/*genetics
Acute Kidney Injury/*metabolism
Apoptosis/*genetics
MicroRNAs/*metabolism
PTEN Phosphohydrolase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Acute Kidney Injury/chemically induced ; Acute Kidney Injury/pathology ; Animals ; Cell Line ; Disease Models, Animal ; Down-Regulation/genetics ; Epithelial Cells ; Inflammation/genetics ; Inflammation/metabolism ; Kidney Tubules/drug effects ; Kidney Tubules/metabolism ; Lipopolysaccharides/toxicity ; Male ; Mice, Inbred C57BL ; Reactive Oxygen Species/metabolism ; Signal Transduction/genetics ; Mice
Czasopismo naukowe
Tytuł:
CIDEC silencing attenuates diabetic nephropathy via inhibiting apoptosis and promoting autophagy.
Autorzy:
Zheng GS; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.; Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Tan YM; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Shang YY; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Liu YP; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Hu BA; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Wang D; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Han L; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.; Department of General Practice, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Wang ZH; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.; Shandong Key Laboratory of Cardiovascular Proteomics, Department of Geriatric Medicine, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Zhang W; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Ti Y; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
Zhong M; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.
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Źródło:
Journal of diabetes investigation [J Diabetes Investig] 2021 Aug; Vol. 12 (8), pp. 1336-1345.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*genetics
Autophagy/*genetics
Diabetic Nephropathies/*genetics
Diabetic Nephropathies/*prevention & control
Proteins/*genetics
Animals ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/pathology ; Diabetic Nephropathies/pathology ; Diet, High-Fat ; Early Growth Response Protein 1/biosynthesis ; Early Growth Response Protein 1/genetics ; Epithelial Cells/pathology ; Gene Silencing ; Kidney Tubules/pathology ; Lipase/biosynthesis ; Lipase/genetics ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid-induced osteonecrosis of the femoral head.
Autorzy:
Yang N; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Sun H; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Xue Y; Department of Orthopaedics, Changshu Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Changshu, China.
Zhang W; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Wang H; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Tao H; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Liang X; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Li M; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Xu Y; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Chen L; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Zhang L; Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Huang L; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Geng D; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2021 Jun; Vol. 11 (6), pp. e447.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Femur Head/*drug effects
Glucocorticoids/*toxicity
Kelch-Like ECH-Associated Protein 1/*metabolism
Monoacylglycerol Lipases/*antagonists & inhibitors
NF-E2-Related Factor 2/*metabolism
Osteonecrosis/*prevention & control
Animals ; Cell Differentiation ; Femur Head/pathology ; Kelch-Like ECH-Associated Protein 1/genetics ; Male ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Mesenchymal Stem Cells/pathology ; NF-E2-Related Factor 2/genetics ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Osteonecrosis/chemically induced ; Osteonecrosis/metabolism ; Osteonecrosis/pathology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Nicotiflorin attenuates cell apoptosis in renal ischemia-reperfusion injury through activating transcription factor 3.
Autorzy:
Wang L; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Li C; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.; Division of Nephrology, Department of Medicine IV, Hospital of the Ludwig Maximilian University of Munich, Munich, Germany.
Guan C; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhang Y; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yang C; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhao L; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Luan H; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhou B; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Che L; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Wang Y; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhang W; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhang H; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Man X; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jiang W; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xu Y; Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
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Źródło:
Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2021 Apr; Vol. 26 (4), pp. 358-368. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
Activating Transcription Factor 3/*drug effects
Activating Transcription Factor 3/*physiology
Apoptosis/*drug effects
Flavonoids/*pharmacology
Flavonoids/*therapeutic use
Kidney/*blood supply
Phenols/*pharmacology
Phenols/*therapeutic use
Reperfusion Injury/*drug therapy
Animals ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Autorzy:
Zhang W; College of Basic Medical Sciences, Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Zhu Y; College of Basic Medical Sciences, Experimental Teacher Center, Naval Medical University, Shanghai 200433, China.
Yu H; College of Basic Medical Sciences, Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Liu X; College of Basic Medical Sciences, Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Jiao B; College of Basic Medical Sciences, Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Lu X; College of Basic Medical Sciences, Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jan 09; Vol. 26 (2). Date of Electronic Publication: 2021 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Biological Products/*pharmacology
Diterpenes/*pharmacology
Pancreatic Neoplasms/*drug therapy
Reactive Oxygen Species/*antagonists & inhibitors
Thioredoxins/*antagonists & inhibitors
Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Ascomycota/chemistry ; Biological Products/chemistry ; Biological Products/isolation & purification ; Cell Proliferation/drug effects ; Diterpenes/chemistry ; Diterpenes/isolation & purification ; Drug Screening Assays, Antitumor ; Humans ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Reactive Oxygen Species/metabolism ; Thioredoxins/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury.
Autorzy:
Cui SY; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Zhang W; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Cui ZM; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Yi H; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Xu DW; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Liu W; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Zhu XH; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jan 06; Vol. 16 (1), pp. 6. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Knockdown Techniques*
Apoptosis/*genetics
Lymphoid Enhancer-Binding Factor 1/*genetics
Lymphoid Enhancer-Binding Factor 1/*physiology
Microglia/*pathology
RNA, Long Noncoding/*genetics
RNA, Long Noncoding/*physiology
Spinal Cord Injuries/*genetics
Spinal Cord Injuries/*pathology
Animals ; Cell Survival/genetics ; Disease Progression ; Down-Regulation ; Inflammation ; Lymphoid Enhancer-Binding Factor 1/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Rats, Sprague-Dawley ; Rats, Wistar ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Up-Regulation ; Rats
Czasopismo naukowe
Tytuł:
Protective Effects of Adiponectin against Cobalt Chloride-Induced Apoptosis of Smooth Muscle Cells via cAMP/PKA Pathway.
Autorzy:
Xiao J; Department of Physiology, Medicine School of Shihezi University, Shihezi, Xinjiang, China.; Department of Biochemistry, Wuhan University School of Basic Medical Sciences, Wuhan, China.
Zhang Y; Department of Physiology, Medicine School of Shihezi University, Shihezi, Xinjiang, China.; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi University, Shihezi, Xinjiang, China.
Zhang W; Department of Gastroenterology, People's Hospital of Jiaozuo city, Jiaozuo, China.
Zhang L; Department of Physiology, Medicine School of Shihezi University, Shihezi, Xinjiang, China.; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi University, Shihezi, Xinjiang, China.
Li L; Department of Physiology, Medicine School of Shihezi University, Shihezi, Xinjiang, China.; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi University, Shihezi, Xinjiang, China.
Si J; Department of Physiology, Medicine School of Shihezi University, Shihezi, Xinjiang, China.; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi University, Shihezi, Xinjiang, China.
Li X; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi University, Shihezi, Xinjiang, China.; Department of Pathophysiology, Medicine School of Shihezi University, Shihezi, Xinjiang, China.
Ma K; Department of Physiology, Medicine School of Shihezi University, Shihezi, Xinjiang, China.; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi University, Shihezi, Xinjiang, China.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Oct 10; Vol. 2020, pp. 7169348. Date of Electronic Publication: 2020 Oct 10 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Adiponectin/*metabolism
Apoptosis/*drug effects
Cobalt/*toxicity
Myocytes, Smooth Muscle/*drug effects
Myocytes, Smooth Muscle/*metabolism
Adiponectin/pharmacology ; Animals ; Apoptosis/physiology ; Cell Survival/drug effects ; Cells, Cultured ; Cochlea/blood supply ; Cyclic AMP/antagonists & inhibitors ; Cyclic AMP/metabolism ; Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Guinea Pigs ; Myocytes, Smooth Muscle/pathology ; Protective Agents/pharmacology ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
MiR-708 inhibits MC3T3-E1 cells against H 2 O 2 -induced apoptosis through targeting PTEN.
Autorzy:
Zhang W; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Suzhou, 215004, Jiangsu, China.
Cui SY; Department of Orthopedics, The First People's Hospital of Nantong, Nantong, 226001, Jiangsu Province, China.
Yi H; Department of Orthopedics, The First People's Hospital of Nantong, Nantong, 226001, Jiangsu Province, China.
Zhu XH; Department of Orthopedics, The First People's Hospital of Nantong, Nantong, 226001, Jiangsu Province, China.
Liu W; Department of Orthopedics, The First People's Hospital of Nantong, Nantong, 226001, Jiangsu Province, China.
Xu YJ; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Suzhou, 215004, Jiangsu, China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2020 Jul 10; Vol. 15 (1), pp. 255. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Apoptosis/*genetics
Hydrogen Peroxide/*adverse effects
MicroRNAs/*pharmacology
MicroRNAs/*physiology
Osteoblasts/*metabolism
Osteoblasts/*physiology
PTEN Phosphohydrolase/*metabolism
3T3 Cells ; Animals ; Cells, Cultured ; Glutathione Peroxidase/metabolism ; Malondialdehyde/metabolism ; Mice ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Propofol promotes apoptosis of colorectal cancer cells via alleviating the suppression of lncRNA HOXA11-AS on miRNA let-7i.
Autorzy:
Ren YL; Department of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.; Department of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhang W; Department of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.; Department of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2020 Apr; Vol. 98 (2), pp. 90-98. Date of Electronic Publication: 2019 Apr 23.
Typ publikacji:
Journal Article
MeSH Terms:
Anesthetics, Intravenous/*pharmacology
Apoptosis/*drug effects
Colorectal Neoplasms/*pathology
Homeodomain Proteins/*genetics
MicroRNAs/*metabolism
Propofol/*pharmacology
RNA, Long Noncoding/*genetics
Caspase 3/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Colorectal Neoplasms/drug therapy ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Multidrug Resistance-Associated Proteins/metabolism ; Oligonucleotides, Antisense/genetics ; Protein Binding
Czasopismo naukowe
Tytuł:
Advanced glycation end products facilitate the proliferation and reduce early apoptosis of cardiac microvascular endothelial cells via PKCβ signaling pathway: Insight from diabetic cardiomyopathy.
Autorzy:
Luan Y; Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University; Zhejiang-P.R. China.
Zhang J; Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University; Zhejiang-P.R. China.
Wang M; Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University; Zhejiang-P.R. China.
Fu G; Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University; Zhejiang-P.R. China.
Zhang W; Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University; Zhejiang-P.R. China.
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Źródło:
Anatolian journal of cardiology [Anatol J Cardiol] 2020 Feb; Vol. 23 (3), pp. 141-150.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Diabetic Cardiomyopathies/*metabolism
Endothelial Cells/*drug effects
Glycation End Products, Advanced/*pharmacology
Protein Kinase C beta/*metabolism
Animals ; Cell Proliferation/drug effects ; Disease Models, Animal ; Male ; Rats ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe

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