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Tytuł:
Optimizing (O) rifapentine-based (RI) regimen and shortening (EN) the treatment of drug-susceptible tuberculosis (T) (ORIENT) using an adaptive seamless design: study protocol of a multicenter randomized controlled trial.
Autorzy:
Feng Z; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Miao Y; Shanghai Huashen Institute of Microbes and Infections, Shanghai, China.
Peng Y; Department of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Zhejiang Province, Hangzhou, People's Republic of China.
Sun F; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Zhang Y; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Li R; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Ge S; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Chen X; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Song L; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Li Y; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. y_.
Wang X; Department of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Zhejiang Province, Hangzhou, People's Republic of China. .
Zhang W; Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. .; Shanghai Huashen Institute of Microbes and Infections, Shanghai, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2023 May 08; Vol. 23 (1), pp. 300. Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Rifampin*/adverse effects
Tuberculosis*/drug therapy
Humans ; Isoniazid/adverse effects ; Pyrazinamide ; Moxifloxacin/therapeutic use ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic ; Clinical Trials, Phase II as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gene expression pattern analysis using dual-color RT-MLPA and integrative genome-wide association studies of eQTL for tuberculosis suscepitibility.
Autorzy:
Ai JW; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Zhang H; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Zhou Z; Department of Infectious Diseases, People's Hospital of Zhuji, 122 Huanshan South Road, Zhuji, 311800, China.
Weng S; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Huang H; Department of Infectious Diseases, People's Hospital of Zhuji, 122 Huanshan South Road, Zhuji, 311800, China.
Wang S; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Shao L; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Gao Y; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Wu J; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Ruan Q; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Wang F; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Jiang N; State Key Laboratory of Genetic Engineering and Institute of Biostatistics and Computational Biology, School of Life Sciences, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China. .
Chen J; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China. jiazhen_.
Zhang W; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China. wenhongzhang_.
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Źródło:
Respiratory research [Respir Res] 2021 Jan 20; Vol. 22 (1), pp. 23. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Asian People/*genetics
Genetic Predisposition to Disease/*genetics
Genome-Wide Association Study/*methods
Quantitative Trait Loci/*genetics
RNA-Directed DNA Polymerase/*genetics
Tuberculosis/*genetics
Adult ; China/epidemiology ; Cohort Studies ; Female ; Gene Expression ; Gene Regulatory Networks/genetics ; Genetic Predisposition to Disease/epidemiology ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide/genetics ; Prospective Studies ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differential expression and predictive value of monocyte scavenger receptor CD163 in populations with different tuberculosis infection statuses.
Autorzy:
Liu Q; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Ou Q; Department of Pulmonary Diseases, Wuxi Infectious Diseases Hospital, Wuxi, 214005, China. .
Chen H; Department of Pulmonary Diseases, Wuxi Infectious Diseases Hospital, Wuxi, 214005, China.
Gao Y; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Liu Y; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Xu Y; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Ruan Q; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.
Zhang W; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.; Key Laboratory of Medical Molecular Virology, Ministry of Education and Health, Shanghai Medical College, and Institutes of Biomedical Science, Fudan University, Shanghai, 200032, China.; State Key Laboratory of Genetic Engineering, School of Life Science, Fudan University, Shanghai, 200438, China.; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Shao L; Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2019 Nov 28; Vol. 19 (1), pp. 1006. Date of Electronic Publication: 2019 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, CD/*analysis
Antigens, Differentiation, Myelomonocytic/*analysis
Monocytes/*metabolism
Receptors, Cell Surface/*analysis
Tuberculosis/*diagnosis
Adult ; Aged ; Antigens, CD/blood ; Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/blood ; Antigens, Differentiation, Myelomonocytic/metabolism ; Area Under Curve ; Case-Control Studies ; Female ; Humans ; Immunity, Innate ; Lipopolysaccharide Receptors/metabolism ; Male ; Middle Aged ; Monocytes/cytology ; Monocytes/immunology ; Prognosis ; ROC Curve ; Receptors, Cell Surface/blood ; Receptors, Cell Surface/metabolism ; Receptors, IgG/metabolism ; Severity of Illness Index ; Tuberculosis/immunology ; Tuberculosis/pathology ; Tuberculosis, Pleural/immunology ; Tuberculosis, Pleural/pathology ; Tuberculosis, Pulmonary/immunology ; Tuberculosis, Pulmonary/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-γ Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection.
Autorzy:
Shao L; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Zhang X; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Gao Y; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Xu Y; Department of Infectious Diseases, Honghe No.1 People's Hospital, Mengzi, Mengzi County, 661100, China.
Zhang S; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Yu S; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Weng X; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Shen H; Chinese Academy of Science and Institute Pasteur of Shanghai, Shanghai, 200040, China.
Chen ZW; Department of Microbiology & Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, 60612, United States of America.
Jiang W; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Zhang W; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China.
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Źródło:
PloS one [PLoS One] 2016 Mar 09; Vol. 11 (3), pp. e0150941. Date of Electronic Publication: 2016 Mar 09 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes/*metabolism
CD8-Positive T-Lymphocytes/*metabolism
Coinfection/*metabolism
HIV Infections/*metabolism
Interferon-gamma/*metabolism
Tuberculosis/*metabolism
Adult ; Aged ; CD4 Lymphocyte Count ; Female ; Flow Cytometry ; Fluorescent Antibody Technique ; Humans ; Male ; Middle Aged ; Mycobacterium tuberculosis/immunology ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Fluctuating Behavior and Influential Factors in the Performance of the QuantiFERON-TB Gold In-Tube Assay in the Diagnosis of Tuberculosis.
Autorzy:
Bao L; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Li T; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China; Department of Tuberculosis Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Diao N; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Shen Y; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Shao L; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Zhang Y; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America.
Lu S; Department of Tuberculosis Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Zhang W; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China; Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2015 Aug 19; Vol. 10 (8), pp. e0103763. Date of Electronic Publication: 2015 Aug 19 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay/*methods
Gold/*immunology
Interferon-gamma Release Tests/*methods
Tuberculin Test/*methods
Tuberculosis/*diagnosis
Adult ; Child, Preschool ; False Negative Reactions ; Female ; Glucocorticoids/chemistry ; Humans ; Immunity, Innate/immunology ; Male ; Middle Aged ; Reagent Kits, Diagnostic ; Sensitivity and Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Interferon-gamma release assay performance in pulmonary and extrapulmonary tuberculosis.
Autorzy:
Feng Y; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Diao N
Shao L
Wu J
Zhang S
Jin J
Wang F
Weng X
Zhang Y
Zhang W
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (3), pp. e32652. Date of Electronic Publication: 2012 Mar 13.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interferon-gamma/*metabolism
Interferon-gamma Release Tests/*methods
Tuberculosis/*diagnosis
Tuberculosis, Pulmonary/*diagnosis
BCG Vaccine ; Diagnosis, Differential ; Humans ; Likelihood Functions ; Predictive Value of Tests ; Sensitivity and Specificity ; Tuberculin ; Tuberculin Test/methods ; Tuberculosis/immunology ; Tuberculosis, Pulmonary/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evaluation of the diagnostic potential of IP-10 and IL-2 as biomarkers for the diagnosis of active and latent tuberculosis in a BCG-vaccinated population.
Autorzy:
Wang S; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Diao N
Lu C
Wu J
Gao Y
Chen J
Zhou Z
Huang H
Shao L
Jin J
Weng X
Zhang Y
Zhang W
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (12), pp. e51338. Date of Electronic Publication: 2012 Dec 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
BCG Vaccine/*metabolism
Chemokine CXCL10/*blood
Interleukin-2/*blood
Latent Tuberculosis/*blood
Tuberculosis/*blood
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antigens/metabolism ; Biomarkers/metabolism ; Cross-Sectional Studies ; Cytokines/metabolism ; Enzyme-Linked Immunosorbent Assay/methods ; Female ; Humans ; Interferon-gamma/metabolism ; Male ; Middle Aged ; Sensitivity and Specificity ; T-Lymphocytes/metabolism ; Time Factors ; Tuberculin Test ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells.
Autorzy:
Lu C; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Wu J
Wang H
Wang S
Diao N
Wang F
Gao Y
Chen J
Shao L
Weng X
Zhang Y
Zhang W
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Źródło:
PloS one [PLoS One] 2011; Vol. 6 (8), pp. e24290. Date of Electronic Publication: 2011 Aug 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers/*analysis
Gene Expression Profiling/*methods
Leukocytes, Mononuclear/*metabolism
Tuberculosis/*metabolism
Adolescent ; Adult ; Aged ; Female ; Humans ; Male ; Microarray Analysis ; Middle Aged ; Real-Time Polymerase Chain Reaction ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Rv1985c, a promising novel antigen for diagnosis of tuberculosis infection from BCG-vaccinated controls.
Autorzy:
Chen J; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
Wang S
Zhang Y
Su X
Wu J
Shao L
Wang F
Zhang S
Weng X
Wang H
Zhang W
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2010 Sep 17; Vol. 10, pp. 273. Date of Electronic Publication: 2010 Sep 17.
Typ publikacji:
Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Bacterial/*immunology
Bacteriological Techniques/*methods
Mycobacterium tuberculosis/*immunology
Tuberculosis/*diagnosis
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Bacterial/blood ; BCG Vaccine/immunology ; Child ; Female ; Humans ; Immunoassay/methods ; Immunoglobulin G/blood ; Interferon-gamma/metabolism ; Middle Aged ; Recombinant Proteins/immunology ; Sensitivity and Specificity ; T-Lymphocytes/immunology ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
High-sensitive and rapid detection of Mycobacterium tuberculosis infection by IFN-gamma release assay among HIV-infected individuals in BCG-vaccinated area.
Autorzy:
Jiang W; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai 200040, PR China. />Shao L
Zhang Y
Zhang S
Meng C
Xu Y
Huang L
Wang Y
Wang Y
Weng X
Zhang W
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Źródło:
BMC immunology [BMC Immunol] 2009 May 28; Vol. 10, pp. 31. Date of Electronic Publication: 2009 May 28.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV/*immunology
HIV Infections/*immunology
Immunocompromised Host/*immunology
Mycobacterium tuberculosis/*immunology
Tuberculosis/*diagnosis
Adult ; Aged ; BCG Vaccine/administration & dosage ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD4-Positive T-Lymphocytes/pathology ; China ; Enzyme-Linked Immunosorbent Assay/methods ; Feasibility Studies ; Female ; HIV/pathogenicity ; HIV Infections/complications ; HIV Infections/microbiology ; Humans ; Interferon-gamma/metabolism ; Male ; Middle Aged ; Mycobacterium tuberculosis/pathogenicity ; Predictive Value of Tests ; Skin Tests ; Tuberculosis/complications ; Tuberculosis/immunology ; Tuberculosis/virology ; Vaccination ; Virulence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Study protocol for safety and efficacy of all-oral shortened regimens for multidrug-resistant tuberculosis: a multicenter randomized withdrawal trial and a single-arm trial [SEAL-MDR]
Autorzy:
Fu, Liang
Xiong, Juan
Wang, Haibo
Zhang, Peize
Yang, Qianting
Cai, Yi
Wang, WenfeiAff1, Aff4
Sun, Feng
Zhang, Xilin
Wang, Zhaoqin
Chen, XinchunAff4, IDs12879023086448_cor11
Zhang, WenhongAff5, IDs12879023086448_cor12
Deng, GuofangAff1, IDs12879023086448_cor13
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Źródło:
BMC Infectious Diseases. 23(1)
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 80

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