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Tytuł:
Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway.
Autorzy:
Song L; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.
Han X; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.
Jia C; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.
Zhang X; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.
Jiao Y; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.
Du T; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.
Xiao S; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China.
Hiscox JA; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Zhou EM; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. .; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China. .
Mu Y; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. .; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, China. .
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Źródło:
Virology journal [Virol J] 2018 Nov 06; Vol. 15 (1), pp. 169. Date of Electronic Publication: 2018 Nov 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Cell Cycle Checkpoints*
Cell Proliferation*
Signal Transduction*
Porcine respiratory and reproductive syndrome virus/*physiology
Animals ; Cell Cycle ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Line ; Checkpoint Kinase 1/genetics ; Checkpoint Kinase 1/metabolism ; Phosphorylation ; Swine ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; cdc25 Phosphatases/genetics ; cdc25 Phosphatases/metabolism ; rho GTP-Binding Proteins/genetics ; rho GTP-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
cfa-miR-143 Promotes Apoptosis via the p53 Pathway in Canine Influenza Virus H3N2-Infected Cells.
Autorzy:
Zhou P; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Tu L; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Lin X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Hao X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Zheng Q; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. qingxu_.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. qingxu_.; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. qingxu_.
Zeng W; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Zhang X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Zheng Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Wang L; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Li S; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
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Źródło:
Viruses [Viruses] 2017 Nov 25; Vol. 9 (12). Date of Electronic Publication: 2017 Nov 25.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Dog Diseases/*virology
Influenza A Virus, H3N2 Subtype/*pathogenicity
Influenza, Human/*virology
MicroRNAs/*genetics
Orthomyxoviridae Infections/*veterinary
Animals ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Count ; Dogs ; Down-Regulation ; Genes, Reporter ; HEK293 Cells ; Humans ; Influenza A Virus, H3N2 Subtype/genetics ; Lung/virology ; Madin Darby Canine Kidney Cells ; Orthomyxoviridae Infections/virology ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of Hylomecon vernalis ethanol extracts on cell cycle and apoptosis of colon cancer cells.
Autorzy:
Sun J; College of Pharmacy, Shannxi University of Chinese Medicine, Xianyang, Shannxi 712046, P.R. China.
Zhang X; College of Pharmacy, Shannxi University of Chinese Medicine, Xianyang, Shannxi 712046, P.R. China.
Sun Y; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, Shannxi 710032, P.R. China.
Tang ZS; College of Pharmacy, Shannxi University of Chinese Medicine, Xianyang, Shannxi 712046, P.R. China.
Guo DY; College of Pharmacy, Shannxi University of Chinese Medicine, Xianyang, Shannxi 712046, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Jun; Vol. 15 (6), pp. 3485-3492. Date of Electronic Publication: 2017 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Cell Cycle/*drug effects
Papaveraceae/*chemistry
Plant Extracts/*pharmacology
Antineoplastic Agents, Phytogenic/chemistry ; Apoptosis/genetics ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Survival/drug effects ; Colonic Neoplasms ; Gene Expression ; Humans ; Mass Spectrometry ; Plant Extracts/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Polypeptides from the Skin of Rana chensinensis Exert the Antioxidant and Antiapoptotic Activities on HaCaT Cells.
Autorzy:
Zhang X; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Cheng Y; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Yang Y; b Institute of Translational Medicine , The First Hospital, Jilin University , Changchun , Jilin Province , China.
Liu S; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Shi H; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Lu C; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Li S; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Nie L; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Su D; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Deng X; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
Ding K; c Department of Radiation Medicine, School of Public Health and Tropic Medicine , Southern Medical University , Guangzhou , Guangzhou Province , China.
Hao L; a College of Animal Science , Jilin University , Changchun , Jilin Province , China.
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Źródło:
Animal biotechnology [Anim Biotechnol] 2017 Jan 02; Vol. 28 (1), pp. 1-10. Date of Electronic Publication: 2016 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*pharmacology
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Peptides/*pharmacology
Ranidae/*metabolism
Skin/*chemistry
Animals ; Antioxidants/isolation & purification ; Apoptosis/radiation effects ; Caspase 3/drug effects ; Cell Line ; Cell Survival/drug effects ; Down-Regulation/drug effects ; Gene Expression Regulation/drug effects ; Humans ; Keratinocytes/drug effects ; Peptides/isolation & purification ; Skin/metabolism ; Ultraviolet Rays ; Up-Regulation/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MicroRNA-203 Is a Prognostic Indicator in Bladder Cancer and Enhances Chemosensitivity to Cisplatin via Apoptosis by Targeting Bcl-w and Survivin.
Autorzy:
Zhang X; Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China.
Zhang Y; Department of Clinical Laboratory, Traffic Hospital of Shandong Province, Jinan, China.
Liu X; Department of Clinical Laboratory, Traffic Hospital of Shandong Province, Jinan, China.
Fang A; Department of Pathology, Traffic Hospital of Shandong Province, Jinan, China.
Li P; Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China.
Li Z; Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China.
Liu T; Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China.
Yang Y; Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China.
Du L; Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China.
Wang C; Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China.
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Źródło:
PloS one [PLoS One] 2015 Nov 23; Vol. 10 (11), pp. e0143441. Date of Electronic Publication: 2015 Nov 23 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Apoptosis Regulatory Proteins/*metabolism
Cisplatin/*therapeutic use
Inhibitor of Apoptosis Proteins/*metabolism
MicroRNAs/*metabolism
Urinary Bladder Neoplasms/*drug therapy
Urinary Bladder Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Base Sequence ; Cell Line, Tumor ; Cisplatin/pharmacology ; Disease Progression ; Disease-Free Survival ; Female ; HEK293 Cells ; Humans ; Male ; MicroRNAs/genetics ; Middle Aged ; Molecular Sequence Data ; Multivariate Analysis ; Prognosis ; Proportional Hazards Models ; Survivin ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Deglucose chikusetsusaponin IVa isolated from Rhizoma Panacis Majoris induces apoptosis in human HepG2 hepatoma cells.
Autorzy:
Song X; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
Wang W; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
Zhang X; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
Jiang Y; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
Yang X; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
Deng C; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
Yue Z; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
Tang Z; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2015 Oct; Vol. 12 (4), pp. 5494-500. Date of Electronic Publication: 2015 Jul 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Drugs, Chinese Herbal/*pharmacology
Oleanolic Acid/*analogs & derivatives
Saponins/*pharmacology
Carcinoma, Hepatocellular ; Cell Cycle Checkpoints/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Hep G2 Cells ; Humans ; Oleanolic Acid/pharmacology ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
SATB1 Mediates Long-Range Chromatin Interactions: A Dual Regulator of Anti-Apoptotic BCL2 and Pro-Apoptotic NOXA Genes.
Autorzy:
Yang Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China; Department of Cell Biology, Nanjing Medical University, Nanjing, PR China.
Wang Z; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China; Department of Cell Biology, Nanjing Medical University, Nanjing, PR China.
Sun L; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China; Department of Cell Biology, Nanjing Medical University, Nanjing, PR China.
Shao L; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China; Department of Cell Biology, Nanjing Medical University, Nanjing, PR China.
Yang N; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China; Department of Cell Biology, Nanjing Medical University, Nanjing, PR China.
Yu D; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China; Department of Cell Biology, Nanjing Medical University, Nanjing, PR China.
Zhang X; Department of Physiology and Stephenson Cancer Center, University of Oklahoma Health Sciences Center, University of Oklahoma, Norman, Oklahoma, United States of America.
Han X; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China.
Sun Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing medical University, Nanjing, PR China; Department of Cell Biology, Nanjing Medical University, Nanjing, PR China; Collaborative Innovation Center for Cancer Personalized Medicine, Jiangsu Key Lab of Cancer Biomarkers, Prevention & Treatment, Cancer Center, Nanjing Medical University, Nanjing, PR China.
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Źródło:
PloS one [PLoS One] 2015 Sep 30; Vol. 10 (9), pp. e0139170. Date of Electronic Publication: 2015 Sep 30 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Chromatin/*metabolism
Matrix Attachment Region Binding Proteins/*metabolism
Proto-Oncogene Proteins c-bcl-2/*genetics
Chromatin/chemistry ; Chromatin/genetics ; Enhancer Elements, Genetic/genetics ; Gene Expression Regulation ; Humans ; Jurkat Cells ; Promoter Regions, Genetic/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Facile and quantitative electrochemical detection of yeast cell apoptosis.
Autorzy:
Yue Q; 1] School of Life Sciences, Anhui Agricultural University, Hefei 230036, People's Republic of China [2].
Xiong S; 1] Key Laboratory of Ion Beam Bioengineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, People's Republic of China [2].
Cai D; Key Laboratory of Ion Beam Bioengineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, People's Republic of China.
Wu Z; Key Laboratory of Ion Beam Bioengineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, People's Republic of China.
Zhang X; School of Life Sciences, Anhui Agricultural University, Hefei 230036, People's Republic of China.
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Źródło:
Scientific reports [Sci Rep] 2014 Mar 14; Vol. 4, pp. 4373. Date of Electronic Publication: 2014 Mar 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Electrochemical Techniques*
Yeasts/*chemistry
Copper/chemistry ; Electrochemistry/methods ; Flow Cytometry ; Saccharomyces cerevisiae/chemistry ; Saccharomyces cerevisiae/metabolism ; Yeasts/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats.
Autorzy:
Wang Y; Department of Clinical Pharmacology, China Medical University, Heping District, Shenyang, PR China.
Zhang XH
Wang HL
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2011 May; Vol. 89 (5), pp. 345-54. Date of Electronic Publication: 2011 May 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Bone Morphogenetic Protein Receptors, Type II/*metabolism
Endothelial Cells/*drug effects
Fluoxetine/*pharmacology
Hypertension, Pulmonary/*chemically induced
Monocrotaline/*pharmacology
Animals ; Blood Pressure/drug effects ; Bone Morphogenetic Protein Receptors, Type II/genetics ; Caspase 3/metabolism ; Cyclic GMP-Dependent Protein Kinases/metabolism ; Endothelial Cells/cytology ; Fluoxetine/therapeutic use ; Gene Expression/drug effects ; Gene Expression/genetics ; Hypertension, Pulmonary/metabolism ; Hypertension, Pulmonary/pathology ; Hypertension, Pulmonary/prevention & control ; Hypertrophy, Right Ventricular/pathology ; Hypertrophy, Right Ventricular/prevention & control ; Lung/blood supply ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Male ; Microvessels/drug effects ; Microvessels/pathology ; Phosphorylation/drug effects ; Pulmonary Artery/drug effects ; Pulmonary Artery/metabolism ; Pulmonary Artery/pathology ; Rats ; Rats, Wistar ; Smad1 Protein/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats.
Autorzy:
Zhai FG; Department of Clinical Pharmacology, China Medical University, Shenyang, China.
Zhang XH
Wang HL
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2009 Aug; Vol. 36 (8), pp. 850-6. Date of Electronic Publication: 2009 Mar 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Fluoxetine/*therapeutic use
Hypertension, Pulmonary/*prevention & control
Kv1.5 Potassium Channel/*biosynthesis
Pulmonary Artery/*drug effects
Selective Serotonin Reuptake Inhibitors/*therapeutic use
Animals ; Blotting, Western ; Cell Proliferation/drug effects ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Fluoxetine/administration & dosage ; Hypertension, Pulmonary/metabolism ; Hypertension, Pulmonary/pathology ; Lung/blood supply ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Lung/physiopathology ; Male ; Monocrotaline ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Pulmonary Artery/pathology ; Pulmonary Artery/physiopathology ; Pulmonary Circulation/drug effects ; Rats ; Rats, Wistar ; Reverse Transcriptase Polymerase Chain Reaction ; Serotonin Plasma Membrane Transport Proteins/biosynthesis ; Selective Serotonin Reuptake Inhibitors/administration & dosage ; Time Factors ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Xanthoxyletin blocks the RANK/RANKL signaling pathway to suppress the growth of human pancreatic cancer cells
Autorzy:
Zhang Xin
Li Luming
Wu Yan
Pokaż więcej
Temat:
pancreatic cancer
coumarin
xanthoxyletin
apoptosis
proliferation
qrt-pcr
Pharmaceutical industry
HD9665-9675
Źródło:
Acta Pharmaceutica, Vol 73, Iss 3, Pp 503-513 (2023)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/1846-9558
Dostęp URL:
https://doaj.org/article/769a299953a2461fb227aa0c977eec12  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 654

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