Autor: "Zhang, Yan" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Clinical Significance and Immune Infiltration Analyses of the Cuproptosis-Related Human Copper Proteome in Gastric Cancer.
Autorzy:: Tang X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Guo T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Wu X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Gan X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Wang Y; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Jia F; Biological Sample Bank, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Zhang Y; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Xing X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Gao X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.
Li Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Cancer Center Ward I, Peking University Cancer Hospital & Institute, No. 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Oct 12; Vol. 12 (10). Date of Electronic Publication: 2022 Oct 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Stomach Neoplasms*/metabolism
Apoptosis*
Humans ; Copper ; Immunohistochemistry ; Proteome/genetics ; RNA ; Tumor Microenvironment

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Skocz do pozycji: 2.

Tytuł:: Low‑calorie sweetener D‑psicose promotes hydrogen peroxide‑mediated apoptosis in C2C12 myogenic cells favoring skeletal muscle cell injury.
Autorzy:: Wei ZJ; Department of Molecular Orthopedics, Beijing Research Institute of Traumatology and Orthopedics, Beijing Jishuitan Hospital, Beijing 100035, P.R. China.
Sun L; Department of Pediatric Cardiology, Heart Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510623, P.R. China.
Li YL; Department of Public Health, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.
Muhammad JS; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.
Wang Y; Department of Molecular Orthopedics, Beijing Research Institute of Traumatology and Orthopedics, Beijing Jishuitan Hospital, Beijing 100035, P.R. China.
Feng QW; Department of Public Health, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.
Zhang YZ; Department of Molecular Orthopedics, Beijing Research Institute of Traumatology and Orthopedics, Beijing Jishuitan Hospital, Beijing 100035, P.R. China.
Inadera H; Department of Public Health, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.
Cui ZG; Department of Public Health, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.
Wu CA; Department of Molecular Orthopedics, Beijing Research Institute of Traumatology and Orthopedics, Beijing Jishuitan Hospital, Beijing 100035, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Jul; Vol. 24 (1). Date of Electronic Publication: 2021 Jun 03.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Fructose/*pharmacology
Hydrogen Peroxide/*adverse effects
Membrane Proteins/*metabolism
Muscle Development/*drug effects
Muscle, Skeletal/*metabolism
Sweetening Agents/*pharmacology
Animals ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Fructose/chemistry ; M Phase Cell Cycle Checkpoints ; MAP Kinase Signaling System/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Membrane Proteins/genetics ; Mice ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 3.

Tytuł:: ANXA7 regulates trophoblast proliferation and apoptosis in preeclampsia.
Autorzy:: Mo HQ; Institute of Shanghai Key Laboratory of Embryo Original Diseases and Shanghai Municipal Key Clinical Specialty Project Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tian FJ; Institute of Shanghai Key Laboratory of Embryo Original Diseases and Shanghai Municipal Key Clinical Specialty Project Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li X; Institute of Shanghai Key Laboratory of Embryo Original Diseases and Shanghai Municipal Key Clinical Specialty Project Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang J; Institute of Shanghai Key Laboratory of Embryo Original Diseases and Shanghai Municipal Key Clinical Specialty Project Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ma XL; Institute of Shanghai Key Laboratory of Embryo Original Diseases and Shanghai Municipal Key Clinical Specialty Project Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zeng WH; Institute of Shanghai Key Laboratory of Embryo Original Diseases and Shanghai Municipal Key Clinical Specialty Project Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lin Y; Institute of Shanghai Key Laboratory of Embryo Original Diseases and Shanghai Municipal Key Clinical Specialty Project Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang Y; Department of Obstetrics and Gynecology, RenMin Hospital of Wuhan University, Wuhan, China.; Pokaż więcej
Źródło:: American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2019 Dec; Vol. 82 (6), pp. e13183. Date of Electronic Publication: 2019 Sep 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Cell Proliferation*
Annexin A7/*metabolism
Pre-Eclampsia/*metabolism
Pregnancy Proteins/*metabolism
Trophoblasts/*metabolism
Adult ; Annexin A7/genetics ; Cell Line ; Female ; Humans ; Pre-Eclampsia/genetics ; Pre-Eclampsia/pathology ; Pregnancy ; Pregnancy Proteins/genetics ; Trophoblasts/pathology

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Skocz do pozycji: 4.

Tytuł:: Eclalbasaponin I causes mitophagy to repress oxidative stress-induced apoptosis via activation of p38 and ERK in SH-SY5Y cells.
Autorzy:: Wang W; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.
Yao GD; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.
Shang XY; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.
Zhang YY; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.
Song XY; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.
Hayashi T; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.; c China-Japan Research Institute of Medical and Pharmaceutical Sciences, Wuya College of Innovation , Shenyang Pharmaceutical University , Shenyang , China.; d Department of Chemistry and Life Science, School of Advanced Engineering , Kogakuin University , Hachioji , Japan.
Zhang Y; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.
Song SJ; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.; b Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development , Shenyang Pharmaceutical University , Shenyang , China.; Pokaż więcej
Źródło:: Free radical research [Free Radic Res] 2019 Jun; Vol. 53 (6), pp. 655-668. Date of Electronic Publication: 2019 Jun 11.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Extracellular Signal-Regulated MAP Kinases/*metabolism
Mitophagy/*drug effects
Neuroprotective Agents/*pharmacology
Oxidative Stress/*drug effects
Saponins/*pharmacology
p38 Mitogen-Activated Protein Kinases/*metabolism
Aralia/chemistry ; Cell Survival/drug effects ; Enzyme Activation/drug effects ; Humans ; Hydrogen Peroxide/antagonists & inhibitors ; Hydrogen Peroxide/pharmacology ; Imidazoles/pharmacology ; Models, Molecular ; Molecular Conformation ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/isolation & purification ; Protein Kinase Inhibitors/pharmacology ; Pyrazoles/pharmacology ; Pyridazines/pharmacology ; Pyridines/pharmacology ; Saponins/chemistry ; Saponins/isolation & purification ; Tumor Cells, Cultured

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Skocz do pozycji: 5.

Tytuł:: Spatiotemporal Correlations between amh and cyp19a1a Transcript Expression and Apoptosis during Gonadal Sex Differentiation of Pejerrey, Odontesthes bonariensis.
Autorzy:: Sarida M
Hattori RS
Zhang Y
Yamamoto Y
Strüssmann CA; Pokaż więcej
Źródło:: Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation [Sex Dev] 2019; Vol. 13 (2), pp. 99-108. Date of Electronic Publication: 2019 Mar 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Developmental*
Anti-Mullerian Hormone/*genetics
Apoptosis/*genetics
Aromatase/*genetics
Fishes/*genetics
Gonads/*growth & development
Sex Differentiation/*genetics
Animals ; Anti-Mullerian Hormone/metabolism ; Aromatase/metabolism ; Female ; Genotype ; Male ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Sex Ratio

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Skocz do pozycji: 6.

Tytuł:: CX-3543 Promotes Cell Apoptosis through Downregulation of CCAT1 in Colon Cancer Cells.
Autorzy:: Yao YX; Department of Digestive Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing 101100, China.
Xu BH; Department of Digestive Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing 101100, China.
Zhang Y; Central Laboratory, Beijing Luhe Hospital, Capital Medical University, Beijing 101100, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2018 Nov 04; Vol. 2018, pp. 9701957. Date of Electronic Publication: 2018 Nov 04 (Print Publication: 2018).
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Benzoxazines/*administration & dosage
Colonic Neoplasms/*drug therapy
Quinolones/*administration & dosage
RNA, Long Noncoding/*genetics
Animals ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; Gene Expression Regulation, Neoplastic/drug effects ; HT29 Cells ; Humans ; Proto-Oncogene Proteins c-myc/genetics ; Rats ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 7.

Tytuł:: The anticancer mechanism investigation of Tanshinone II A by pharmacological clustering in protein network.
Autorzy:: Cao YF; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100102, China.; Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 100029, China.
Wang SF; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100102, China.
Li X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100102, China.
Zhang YL; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100102, China. collean_zhang@163.com.
Qiao YJ; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100102, China. .; Pokaż więcej
Źródło:: BMC systems biology [BMC Syst Biol] 2018 Oct 29; Vol. 12 (1), pp. 90. Date of Electronic Publication: 2018 Oct 29.
Typ publikacji:: Journal Article
MeSH Terms:: Computational Biology*
Abietanes/*pharmacology
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Abietanes/therapeutic use ; Autophagy/drug effects ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Gene Ontology ; Humans ; Neovascularization, Pathologic/drug therapy

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Skocz do pozycji: 8.

Tytuł:: Melatonin protects H9c2 cells against ischemia/reperfusion‑induced apoptosis and oxidative stress via activation of the Nrf2 signaling pathway.
Autorzy:: Zhang Y; Department of Anesthesiology, Heze Municipal Hospital, Heze, Shandong 274031, P.R. China.
Qiao B; Department of Anesthesiology, Heze Municipal Hospital, Heze, Shandong 274031, P.R. China.
Gao F; Department of Anesthesiology, Heze Municipal Hospital, Heze, Shandong 274031, P.R. China.
Wang H; Department of Anesthesiology, Heze Municipal Hospital, Heze, Shandong 274031, P.R. China.
Miao S; Department of Anesthesiology, Heze Municipal Hospital, Heze, Shandong 274031, P.R. China.
Zhao H; Department of Anesthesiology, Heze Municipal Hospital, Heze, Shandong 274031, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Sep; Vol. 18 (3), pp. 3497-3505. Date of Electronic Publication: 2018 Jul 24.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Melatonin/*pharmacology
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Signal Transduction/*drug effects
Animals ; Antioxidants/pharmacology ; Caspase 3/metabolism ; Cell Line ; Cell Survival/drug effects ; Cells, Cultured ; Myocardial Reperfusion Injury/metabolism ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 9.

Tytuł:: Effects of microRNA-133b on retinal vascular endothelial cell proliferation and apoptosis through angiotensinogen-mediated angiotensin II- extracellular signal-regulated kinase 1/2 signalling pathway in rats with diabetic retinopathy.
Autorzy:: Liu TT; Department of Ophthalmology, First Hospital of Jilin University, Changchun, China.
Hao Q; Department of Ophthalmology, First Hospital of Jilin University, Changchun, China.
Zhang Y; Department of Otorhinolaryngology, Head and Neck Surgery, First Hospital of Jilin University, Changchun, China.
Li ZH; Department of Ophthalmology, People's Hospital of Changchun City, Changchun, China.
Cui ZH; Department of Ophthalmology, First Hospital of Jilin University, Changchun, China.
Yang W; Department of Ophthalmology, First Hospital of Jilin University, Changchun, China.; Pokaż więcej
Źródło:: Acta ophthalmologica [Acta Ophthalmol] 2018 Aug; Vol. 96 (5), pp. e626-e635. Date of Electronic Publication: 2018 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Experimental*
Gene Expression Regulation*
Angiotensin II/*metabolism
Apoptosis/*genetics
Diabetic Retinopathy/*genetics
MAP Kinase Signaling System/*physiology
MicroRNAs/*genetics
Animals ; Blotting, Western ; Cell Proliferation ; Cells, Cultured ; Diabetic Retinopathy/metabolism ; Diabetic Retinopathy/pathology ; Flow Cytometry ; Immunohistochemistry ; Male ; MicroRNAs/biosynthesis ; RNA/genetics ; Rats ; Rats, Sprague-Dawley ; Real-Time Polymerase Chain Reaction ; Signal Transduction

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Skocz do pozycji: 10.

Tytuł:: Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells.
Autorzy:: Zhang HW; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Hu JJ; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Fu RQ; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Liu X; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Zhang YH; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Li J; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Liu L; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Li YN; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Deng Q; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Luo QS; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Ouyang Q; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China.
Gao N; College of Pharmacy, 3rd Military Medical University, Chongqing, 400038, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2018 Jul 26; Vol. 8 (1), pp. 11255. Date of Electronic Publication: 2018 Jul 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phosphoinositide-3 Kinase Inhibitors*
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Autophagy/*drug effects
Cell Proliferation/*drug effects
Flavonoids/*pharmacology
Signal Transduction/*drug effects
Autophagy-Related Protein-1 Homolog/metabolism ; Cell Line, Tumor ; Class Ib Phosphatidylinositol 3-Kinase ; Down-Regulation ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Oncogene Protein v-akt/metabolism ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; TOR Serine-Threonine Kinases/metabolism

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Skocz do pozycji: 11.

Tytuł:: Effect of ATP and Bax on the apoptosis of Eimeria tenella host cells.
Autorzy:: Xu Z; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.; College of Animal Science and Technology, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Zheng M; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China. .
Zhang L; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.
Zhang X; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.
Zhang Y; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.
Cui X; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.
Gong X; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.
Xi R; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.
Bai R; College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030801, China.; Pokaż więcej
Źródło:: BMC veterinary research [BMC Vet Res] 2017 Dec 28; Vol. 13 (1), pp. 399. Date of Electronic Publication: 2017 Dec 28.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine Triphosphate/*pharmacology
Apoptosis/*drug effects
Eimeria tenella/*drug effects
bcl-2-Associated X Protein/*pharmacology
Animals ; Chickens/parasitology ; Coccidiosis/drug therapy ; Coccidiosis/microbiology ; Flow Cytometry/veterinary ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/parasitology

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Skocz do pozycji: 12.

Tytuł:: Interference of Apoptosis by Hepatitis B Virus.
Autorzy:: Lin S; Molecular Virology Laboratory, VA-MD College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA. .
Zhang YJ; Molecular Virology Laboratory, VA-MD College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2017 Aug 18; Vol. 9 (8). Date of Electronic Publication: 2017 Aug 18.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Hepatitis B/*physiopathology
Hepatitis B virus/*physiology
Liver Neoplasms/*physiopathology
Animals ; Gene Expression Regulation, Neoplastic ; Hepatitis B/genetics ; Hepatitis B/metabolism ; Hepatitis B/virology ; Hepatitis B virus/genetics ; Humans ; Liver Neoplasms/virology

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Skocz do pozycji: 13.

Tytuł:: 2,5-hexanedione downregulates nerve growth factor and induces neuron apoptosis in the spinal cord of rats via inhibition of the PI3K/Akt signaling pathway.
Autorzy:: Wang Z; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.
Qiu Z; Laboratory Animal center, Dalian Medical University, Dalian, Liaoning, China.
Gao C; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.
Sun Y; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.
Dong W; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.
Zhang Y; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.
Chen R; Department of Sexually Transmitted Disease, Heping Center for Disease Control and Prevention of Tianjin, Tianjin, China.
Qi Y; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.
Li S; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.
Guo Y; Department of Biochemistry, Dalian Medical University, Dalian, Liaoning, China.
Piao Y; Department of Dermatology, the First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Li S; Department of Biochemistry, Dalian Medical University, Dalian, Liaoning, China.
Piao F; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Jun 27; Vol. 12 (6), pp. e0179388. Date of Electronic Publication: 2017 Jun 27 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Down-Regulation/*drug effects
Hexanones/*pharmacology
Nerve Growth Factor/*metabolism
Neurons/*drug effects
Signal Transduction/*drug effects
Spinal Cord/*drug effects
Animals ; Caspase 3/metabolism ; Male ; Neurons/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Spinal Cord/metabolism

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Skocz do pozycji: 14.

Tytuł:: Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway.
Autorzy:: Xie X; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Zhao Y; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Ma CY; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Xu XM; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Zhang YQ; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Wang CG; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Jin J; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Shen X; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Gao JL; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Li N; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.
Sun ZJ; Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin, China.
Dong DL; Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2015 Aug; Vol. 172 (15), pp. 3929-43. Date of Electronic Publication: 2015 Jun 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Colonic Neoplasms/*pathology
Dimethyl Fumarate/*adverse effects
Glutathione/*metabolism
MAP Kinase Signaling System/*drug effects
Mitogen-Activated Protein Kinases/*metabolism
Necrosis/*chemically induced
Reactive Oxygen Species/*metabolism
Animals ; Cell Line, Tumor ; Cell Survival/drug effects ; Colonic Neoplasms/enzymology ; Colonic Neoplasms/metabolism ; Fumarates/adverse effects ; HMGB1 Protein/metabolism ; Humans ; L-Lactate Dehydrogenase/metabolism ; Maleates/adverse effects ; Membrane Potential, Mitochondrial/drug effects ; Methanol/adverse effects ; Mice ; Necrosis/metabolism

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Skocz do pozycji: 15.

Tytuł:: Compound 331 selectively induces glioma cell death by upregulating miR-494 and downregulating CDC20.
Autorzy:: Zhang L; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China.
Niu T; 1] Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking University, Beijing, China [2] Aviation Medicine Research Laboratory, The General Hospital of the Air Force, Beijing, China.
Huang Y; Laboratory of Computer-Aided Drug Design &Discovery, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zhu H; Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
Zhong W; Laboratory of Computer-Aided Drug Design &Discovery, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Lin J; Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
Zhang Y; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2015 Jul 08; Vol. 5, pp. 12003. Date of Electronic Publication: 2015 Jul 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Cdc20 Proteins/*metabolism
Down-Regulation/*drug effects
MicroRNAs/*metabolism
Pyridines/*pharmacology
Thiosemicarbazones/*pharmacology
Up-Regulation/*drug effects
Animals ; Astrocytes/cytology ; Astrocytes/drug effects ; Cell Cycle Checkpoints/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Female ; Glioma/drug therapy ; Glioma/metabolism ; Glioma/pathology ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Pyridines/chemistry ; Pyridines/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Thiosemicarbazones/chemistry ; Thiosemicarbazones/therapeutic use ; Transplantation, Heterologous

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Skocz do pozycji: 16.

Tytuł:: Abnormal expression of CD66a promotes proliferation and inhibits apoptosis of human leukemic B cells in vitro.
Autorzy:: Zhao W; Center of Laboratory Technology, China Medical University , Shenyang, Liaoning , China.
Zhang Y
Liu D
Zhong L
He Q
Zhao Y; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2015 Jan; Vol. 56 (1), pp. 202-10. Date of Electronic Publication: 2014 Jun 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression*
Antigens, CD/*genetics
Apoptosis/*genetics
Cell Adhesion Molecules/*genetics
Leukemia, B-Cell/*genetics
Antigens, CD/metabolism ; Caspases/metabolism ; Cell Adhesion Molecules/metabolism ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cell Proliferation ; Fas Ligand Protein/genetics ; Fas Ligand Protein/metabolism ; Granulocytes/metabolism ; Humans ; Leukemia, B-Cell/metabolism ; Protein Isoforms ; RNA Interference ; RNA, Small Interfering/genetics

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Skocz do pozycji: 17.

Tytuł:: A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes of Spodoptera litura after parasitization by Microplitis bicoloratus.
Autorzy:: Li M; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Pang Z; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Xiao W; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Liu X; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Zhang Y; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Yu D; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Yang M; Shanghai-Ministry of Science and Technology Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, P. R. China.
Yang Y; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Hu J; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.
Luo K; School of Life Sciences, Yunnan University, Kunming, P. R. China; Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming, P. R. China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Oct 28; Vol. 9 (10), pp. e110967. Date of Electronic Publication: 2014 Oct 28 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Gene Expression Regulation*
Transcriptome*
Wasps*
Hemocytes/*metabolism
Spodoptera/*metabolism
Animals ; Cell Membrane Permeability ; DNA Fragmentation ; Gene Expression Profiling ; Hemocytes/cytology ; Hemocytes/parasitology ; Host-Parasite Interactions ; Immunosuppression Therapy ; Lectins, C-Type/chemistry ; Mitochondrial Membrane Transport Proteins/metabolism ; Mitochondrial Membranes ; Mitochondrial Permeability Transition Pore ; NF-kappa B/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; Spodoptera/parasitology ; Transcription, Genetic

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Skocz do pozycji: 18.

Tytuł:: N-acetylcysteine attenuates ischemia-reperfusion-induced apoptosis and autophagy in mouse liver via regulation of the ROS/JNK/Bcl-2 pathway.
Autorzy:: Wang C; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Chen K; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xia Y; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Dai W; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Wang F; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Shen M; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Cheng P; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Wang J; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Lu J; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhang Y; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yang J; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhu R; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhang H; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Li J; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zheng Y; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhou Y; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Guo C; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Sep 29; Vol. 9 (9), pp. e108855. Date of Electronic Publication: 2014 Sep 29 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetylcysteine/*pharmacology
Apoptosis/*drug effects
Autophagy/*drug effects
Liver/*blood supply
Liver/*pathology
MAP Kinase Signaling System/*drug effects
Proto-Oncogene Proteins c-bcl-2/*metabolism
Reactive Oxygen Species/*metabolism
Acetylcysteine/therapeutic use ; Animals ; Cytokines/metabolism ; Intracellular Space/metabolism ; Liver/drug effects ; Liver/enzymology ; Male ; Mice, Inbred BALB C ; Protective Agents/pharmacology ; Protective Agents/therapeutic use ; Reperfusion Injury/drug therapy ; Reperfusion Injury/enzymology ; Reperfusion Injury/pathology ; Reperfusion Injury/prevention & control

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Skocz do pozycji: 19.

Tytuł:: Cryptotanshinone inhibits lung tumorigenesis and induces apoptosis in cancer cells in vitro and in vivo.
Autorzy:: Chen L; Department of Respiratory Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, Liaoning 116023, P.R. China.
Wang HJ; Department of Tumor Chemotherapy, Wuwei Tumor Hospital, Wuwei, Gansu 733000, P.R. China.
Xie W; Department of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, Liaoning 116023, P.R. China.
Yao Y; Research Center for Biochemistry and Molecular Biology, Xuzhou Medical College, Xuzhou, Jiangsu 221004, P.R. China.
Zhang YS; Department of Tumor Surgery, Wuwei Tumor Hospital, Wuwei, Gansu 733000, P.R. China.
Wang H; Department of Respiratory Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, Liaoning 116023, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2014 Jun; Vol. 9 (6), pp. 2447-52. Date of Electronic Publication: 2014 Mar 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Cell Transformation, Neoplastic/*drug effects
Drugs, Chinese Herbal/*pharmacology
Phenanthrenes/*pharmacology
Animals ; Apoptosis/genetics ; Body Weight ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Transformation, Neoplastic/genetics ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Humans ; Lung Neoplasms/etiology ; Lung Neoplasms/pathology ; Mice ; Tumor Burden ; Tumor Stem Cell Assay ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 20.

Tytuł:: α-Melanocyte-stimulating hormone protects retinal vascular endothelial cells from oxidative stress and apoptosis in a rat model of diabetes.
Autorzy:: Zhang L; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.
Dong L; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.
Liu X; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.
Jiang Y; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.
Zhang L; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.
Zhang X; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.
Li X; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.
Zhang Y; Tianjin Medical University Eye Hospital/Eye Institute, Tianjin, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Apr 02; Vol. 9 (4), pp. e93433. Date of Electronic Publication: 2014 Apr 02 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*physiology
Diabetes Mellitus, Experimental/*metabolism
Endothelial Cells/*metabolism
Oxidative Stress/*physiology
Retina/*metabolism
alpha-MSH/*metabolism
Animals ; Apoptosis/genetics ; Diabetes Mellitus, Experimental/genetics ; Diabetic Retinopathy/genetics ; Diabetic Retinopathy/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Gene Expression/genetics ; Hydrogen Peroxide/metabolism ; Intercellular Adhesion Molecule-1/genetics ; Intercellular Adhesion Molecule-1/metabolism ; Male ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Oxidative Stress/genetics ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Up-Regulation/genetics ; Up-Regulation/physiology ; alpha-MSH/genetics

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