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Wyświetlanie 1-20 z 654
Tytuł:
Simvastatin inhibits the inflammation and oxidative stress of human neutrophils in sepsis via autophagy induction.
Autorzy:
Xu L; Intensive Care Unit, Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
Wu XM; Intensive Care Unit, Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
Zhang YK; Intensive Care Unit, Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
Huang MJ; Intensive Care Unit, Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
Chen J; Intensive Care Unit, Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Jan; Vol. 25 (1). Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy/*drug effects
Inflammation/*drug therapy
Neutrophils/*metabolism
Oxidative Stress/*drug effects
Sepsis/*metabolism
Simvastatin/*pharmacology
Adult ; Aged ; Animals ; Beclin-1/metabolism ; Cell Survival/drug effects ; Cytokines/metabolism ; Female ; Humans ; Inflammation Mediators/metabolism ; Interleukin-6/metabolism ; Male ; Middle Aged ; Reactive Oxygen Species/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model.
Autorzy:
Ji W; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Zhu P; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Liang R; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Zhang L; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Zhang Y; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Wang Y; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Zhang W; Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA.
Tao L; School of Public Health, Xinxiang Medical University, Xinxiang 453003, China.
Chen S; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Yang H; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Jin Y; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Duan G; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.; Henan Key Laboratory of Molecular Medicine, Zhengzhou University, Zhengzhou 450001, China.
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Źródło:
Viruses [Viruses] 2021 Aug 11; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coxsackievirus Infections/*complications
Enterovirus/*pathogenicity
Heart/*virology
Heart Injuries/*virology
Inflammation/*virology
Animals ; Animals, Newborn ; Apoptosis ; Cytokines/classification ; Cytokines/genetics ; Cytokines/immunology ; Disease Models, Animal ; Enterovirus/classification ; Inflammation/immunology ; Matrix Metalloproteinases/classification ; Matrix Metalloproteinases/genetics ; Matrix Metalloproteinases/immunology ; Mice ; Mice, Inbred BALB C ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Actin-Binding Proteins as Potential Biomarkers for Chronic Inflammation-Induced Cancer Diagnosis and Therapy.
Autorzy:
Zhang YG; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Niu JT; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Wu HW; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Si XL; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Zhang SJ; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Li DH; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Bian TT; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Li YF; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.; Key Laboratory of Standard and Quality of Chinese Medicine Research of Gansu, Engineering Research Center of Chinese Medicine Pharmaceutical Process of Gansu, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Yan XK; Laboratory of Molecular Biology, College of Acupuncture-Moxibustion and Tuina, Gansu University of Chinese Medicine, Lanzhou 730000, China.
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Źródło:
Analytical cellular pathology (Amsterdam) [Anal Cell Pathol (Amst)] 2021 Jun 05; Vol. 2021, pp. 6692811. Date of Electronic Publication: 2021 Jun 05 (Print Publication: 2021).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor/*metabolism
Inflammation/*metabolism
Microfilament Proteins/*metabolism
Neoplasms/*metabolism
Actins/metabolism ; Chronic Disease ; Cytoskeleton/metabolism ; Disease Progression ; Humans ; Inflammation/pathology ; Neoplasms/diagnosis ; Neoplasms/therapy ; Polymerization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis.
Autorzy:
Francisco J; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Zhang Y; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Nakada Y; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Jeong JI; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Huang CY; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Ivessa A; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Oka S; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Babu GJ; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA.
Del Re DP; Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, 185 South Orange Avenue, MSB G-609, Newark, NJ, 07103, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 May 18; Vol. 11 (1), pp. 10553. Date of Electronic Publication: 2021 May 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Vectors*
Dependovirus/*genetics
Fibrosis/*pathology
Inflammation/*genetics
Myofibroblasts/*metabolism
Transcription Factors/*genetics
Animals ; Gene Expression Regulation ; HEK293 Cells ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Myocardium/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Peroxiredoxin 1 as an inflammatory marker in diarrhea-predominant and postinfectious irritable bowel syndrome.
Autorzy:
Zhang Y; School of Nursing, Yangzhou University, Yangzhou, China.; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou, China.
Wu XX; School of Nursing, Yangzhou University, Yangzhou, China.
Li S; School of Nursing, Yangzhou University, Yangzhou, China.
Wu JF; School of Nursing, Yangzhou University, Yangzhou, China.
Han S; Department of Immunology, School of Medicine, Yangzhou University, Yangzhou, China.
Lin ZJ; Department of Immunology, School of Medicine, Yangzhou University, Yangzhou, China.
Ding SZ; Department of Immunology, School of Medicine, Yangzhou University, Yangzhou, China.
Gong WJ; School of Nursing, Yangzhou University, Yangzhou, China.; Department of Immunology, School of Medicine, Yangzhou University, Yangzhou, China.
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Źródło:
Neurogastroenterology and motility [Neurogastroenterol Motil] 2020 Feb; Vol. 32 (2), pp. e13741. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers/*metabolism
Inflammation/*metabolism
Intestinal Mucosa/*metabolism
Irritable Bowel Syndrome/*metabolism
Peroxiredoxins/*metabolism
Adult ; Cross-Sectional Studies ; Diarrhea/etiology ; Female ; Humans ; Irritable Bowel Syndrome/complications ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Effects of Antimicrobial Peptide Nal-P-113 on Inhibiting Periodontal Pathogens and Improving Periodontal Status.
Autorzy:
Wang H; Department of Periodontics, School of Stomatology, China Medical University, Shenyang 110002, China.
Ai L; Department of Periodontics, Jinan Stomatological Hospital, Jinan 250001, China.
Zhang Y; Shenyang Dental Hospital, Shenyang 110002, China.
Cheng J; Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Yu H; Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.
Li C; Department of Periodontics, School of Stomatology, China Medical University, Shenyang 110002, China.
Zhang D; Department of Periodontics, School of Stomatology, China Medical University, Shenyang 110002, China.
Pan Y; Department of Periodontics, School of Stomatology, China Medical University, Shenyang 110002, China.
Lin L; Department of Periodontics, School of Stomatology, China Medical University, Shenyang 110002, China.
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Źródło:
BioMed research international [Biomed Res Int] 2018 Mar 15; Vol. 2018, pp. 1805793. Date of Electronic Publication: 2018 Mar 15 (Print Publication: 2018).
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Anti-Bacterial Agents/*administration & dosage
Inflammation/*drug therapy
Peptides/*administration & dosage
Periodontal Diseases/*drug therapy
Adult ; Anti-Bacterial Agents/chemistry ; Biofilms/drug effects ; Female ; Fusobacterium nucleatum/drug effects ; Fusobacterium nucleatum/pathogenicity ; Gingiva/drug effects ; Gingiva/microbiology ; Humans ; Inflammation/microbiology ; Inflammation/pathology ; Male ; Middle Aged ; Peptides/chemistry ; Periodontal Diseases/microbiology ; Periodontal Pocket/drug therapy ; Periodontal Pocket/microbiology ; Porphyromonas gingivalis/drug effects ; Porphyromonas gingivalis/pathogenicity ; Streptococcus gordonii/drug effects ; Streptococcus gordonii/pathogenicity ; Treponema denticola/drug effects ; Treponema denticola/pathogenicity ; beta-Alanine/analogs & derivatives ; beta-Alanine/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain.
Autorzy:
Zhang C; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, 100191, P.R. China.; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, P.R. China.
Chen RX; Research Center for Medicine and Biology, Zunyi Medical University, Zunyi, 563000, P.R. China.
Zhang Y; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, 100191, P.R. China.
Wang J; Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, 430071, P.R. China.
Liu FY; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, 100191, P.R. China.
Cai J; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, 100191, P.R. China.
Liao FF; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, 100191, P.R. China.
Xu FQ; Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, 430071, P.R. China.
Yi M; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, 100191, P.R. China. .
Wan Y; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, 100191, P.R. China. .; Key Laboratory for Neuroscience, Ministry of Education/National Health and Family Planning Commission, Beijing, 100191, P.R. China. .
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Źródło:
Scientific reports [Sci Rep] 2017 Feb 02; Vol. 7, pp. 41439. Date of Electronic Publication: 2017 Feb 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Synaptic Transmission*
Chronic Pain/*physiopathology
GABAergic Neurons/*physiology
Hyperalgesia/*physiopathology
Inflammation/*physiopathology
Thalamus/*physiopathology
Animals ; Chronic Pain/complications ; Extracellular Space/metabolism ; Freund's Adjuvant ; Gene Knockout Techniques ; Hyperalgesia/complications ; Inflammation/complications ; Isoxazoles/pharmacology ; Male ; Muscimol/pharmacology ; Optogenetics ; Patch-Clamp Techniques ; Protein Subunits/metabolism ; Rats, Sprague-Dawley ; Receptors, GABA-A/metabolism ; Thalamus/pathology ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Plaque Thrombosis is Reduced by Attenuating Plaque Inflammation with Pioglitazone and is Evaluated by Fluorodeoxyglucose Positron Emission Tomography.
Autorzy:
Zhang MD; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.
Zhao XC; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.
Zhang YH; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.
Yan YF; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.
Wang ZM; Center for PET/CT, General Hospital of Second Artillery of PLA, Beijing, China.
Lv SZ; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.
Zhao QM; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.
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Źródło:
Cardiovascular therapeutics [Cardiovasc Ther] 2015 Jun; Vol. 33 (3), pp. 118-26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypoglycemic Agents/*pharmacology
Inflammation/*drug therapy
Plaque, Atherosclerotic/*drug therapy
Thiazolidinediones/*pharmacology
Thrombosis/*prevention & control
Animals ; Biomarkers ; Blood Glucose ; C-Reactive Protein/metabolism ; Fluorodeoxyglucose F18 ; Lipids/blood ; Male ; Matrix Metalloproteinase 9/metabolism ; Pioglitazone ; Positron-Emission Tomography ; Rabbits ; Tomography, X-Ray Computed
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The association of platelet count with clinicopathological significance and prognosis in renal cell carcinoma: a systematic review and meta-analysis.
Autorzy:
Gu L; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Li H; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Gao Y; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Ma X; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Chen L; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Li X; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Zhang Y; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Fan Y; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
Zhang X; Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, No. 28 Fuxing Road, Beijing 100853, P.R. China.
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Źródło:
PloS one [PLoS One] 2015 May 08; Vol. 10 (5), pp. e0125538. Date of Electronic Publication: 2015 May 08 (Print Publication: 2015).
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:
Platelet Count*
Prognosis*
Carcinoma, Renal Cell/*epidemiology
Inflammation/*epidemiology
Carcinoma, Renal Cell/blood ; Carcinoma, Renal Cell/pathology ; Disease-Free Survival ; Humans ; Inflammation/blood ; Inflammation/pathology ; Neoplasm Metastasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Endoplasmic reticulum is at the crossroads of autophagy, inflammation, and apoptosis signaling pathways and participates in the pathogenesis of diabetes mellitus.
Autorzy:
Su J; Department of Pathophysiology, Norman Bethune College of Medicine, Jilin University, Changchun, China.
Zhou L
Kong X
Yang X
Xiang X
Zhang Y
Li X
Sun L
Pokaż więcej
Źródło:
Journal of diabetes research [J Diabetes Res] 2013; Vol. 2013, pp. 193461. Date of Electronic Publication: 2013 May 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Apoptosis/*physiology
Autophagy/*physiology
Diabetes Mellitus/*etiology
Endoplasmic Reticulum/*metabolism
Endoplasmic Reticulum Stress/*physiology
Inflammation/*metabolism
Animals ; Diabetes Mellitus/metabolism ; Diabetes Mellitus/physiopathology ; Humans ; Inflammation/physiopathology ; Signal Transduction/physiology ; Unfolded Protein Response/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 654

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