Autor: "Zhao, Xue-Shan" - OpacWWW

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Tytuł:: Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression.
Autorzy:: Zhao XS; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Wu Q; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Peng J; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Pan LH; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Ren Z; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Liu HT; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Jiang ZS; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Wang GX; College of Bioengineering, Chongqing University, Chongqing 400030, P.R. China.
Tang ZH; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.
Liu LS; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan University of South China, Hengyang, Hunan 421001, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 Feb; Vol. 15 (2), pp. 712-718. Date of Electronic Publication: 2016 Dec 16.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation*
Apolipoproteins E/*genetics
Apoptosis/*genetics
Hyperlipidemias/*physiopathology
Neurons/*metabolism
Proprotein Convertase 9/*genetics
Amyloid Precursor Protein Secretases/metabolism ; Animals ; Apolipoproteins E/deficiency ; Caspase 3/metabolism ; Cholesterol/blood ; Diet, High-Fat ; Hippocampus/cytology ; Hippocampus/metabolism ; Hyperlipidemias/metabolism ; Immunohistochemistry ; Mice ; Mice, Knockout ; Neurons/cytology ; Proprotein Convertase 9/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Triglycerides/blood ; bcl-2-Associated X Protein/metabolism

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