- Tytuł:
-
Enhanced chemosensitivity by simultaneously inhibiting cell cycle progression and promoting
apoptosis of drug-resistant osteosarcoma MG63/DXR cells by targeting Cyclin D1 and Bcl-2. - Autorzy:
- Źródło:
- Cancer biomarkers : section A of Disease markers [Cancer Biomark] 2012; Vol. 12 (4), pp. 155-67.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Drug Resistance, Neoplasm*
Antibiotics, Antineoplastic/*pharmacologyApoptosis /*drug effects
Cyclin D1/*metabolism
Doxorubicin/*pharmacology
Proto-Oncogene Proteins c-bcl-2/*metabolism
Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclin D1/genetics ; Gene Expression ; Gene Knockdown Techniques ; Genetic Vectors ; Humans ; Inhibitory Concentration 50 ; Lentivirus/genetics ; Osteosarcoma ; Proto-Oncogene Proteins c-bcl-2/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/genetics
Czasopismo naukowe