Caprine Bactenecins as Promising Tools for Developing New Antimicrobial and Antitumor Drugs.
Autorzy :
Kopeikin PM; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. ZharkovaMS; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Kolobov AA; Laboratory of Peptide Chemistry, State Research Institute of Highly Pure Biopreparations, Saint Petersburg, Russia. Smirnova MP; Laboratory of Peptide Chemistry, State Research Institute of Highly Pure Biopreparations, Saint Petersburg, Russia. Sukhareva MS; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Umnyakova ES; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Kokryakov VN; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Orlov DS; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Milman BL; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Balandin SV; Science-Educational Center, M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Moscow, Russia. Panteleev PV; Science-Educational Center, M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Moscow, Russia. Ovchinnikova TV; Science-Educational Center, M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Moscow, Russia.; Department of Biotechnology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia. Komlev AS; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Tossi A; Department of Life Sciences, University of Trieste, Trieste, Italy. Shamova OV; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia.
Umnyakova ES; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, Saint Petersburg, Russia. ZharkovaMS; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, Saint Petersburg, Russia. Berlov MN; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, Saint Petersburg, Russia. Shamova OV; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, Saint Petersburg, Russia. Kokryakov VN; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, Saint Petersburg, Russia.; Faculty of Biology, Department of Biochemistry, Saint Petersburg State University, Saint Petersburg, Russia.
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Źródło :
Autoimmunity [Autoimmunity] 2020 May; Vol. 53 (3), pp. 137-147. Date of Electronic Publication: 2020 Jan 08.
Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina , by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization.
Autorzy :
Orlov DS; Institute of Experimental Medicine, 12 Academic Pavlov str., St. Petersburg 197376, Russia. . Shamova OV; Institute of Experimental Medicine, 12 Academic Pavlov str., St. Petersburg 197376, Russia. . Eliseev IE; St. Petersburg Academic University, 8/3 Khlopina str., St. Petersburg 194021, Russia. . ZharkovaMS; Institute of Experimental Medicine, 12 Academic Pavlov str., St. Petersburg 197376, Russia. . Chakchir OB; St. Petersburg Academic University, 8/3 Khlopina str., St. Petersburg 194021, Russia. . Antcheva N; Department of Life Sciences, University of Trieste, Building Q, Via Giorgieri 5, 34127 Trieste, Italy. . Zachariev S; International Centre for Genetic Engineering and Biotechnology, AREA Science Park, Padriciano 99, 34149 Trieste, Italy. . Panteleev PV; M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. . Kokryakov VN; Institute of Experimental Medicine, 12 Academic Pavlov str., St. Petersburg 197376, Russia. . Ovchinnikova TV; M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. .; Department of Biotechnology, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia. . Tossi A; Department of Life Sciences, University of Trieste, Building Q, Via Giorgieri 5, 34127 Trieste, Italy. .
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Źródło :
Marine drugs [Mar Drugs] 2019 Jun 23; Vol. 17 (6). Date of Electronic Publication: 2019 Jun 23.
Application of Antimicrobial Peptides of the Innate Immune System in Combination With Conventional Antibiotics-A Novel Way to Combat Antibiotic Resistance?
Autorzy :
ZharkovaMS; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Orlov DS; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia. Golubeva OY; Laboratory of Nanostructures Research, Institute of Silicate Chemistry of the Russian Academy of Sciences, Saint Petersburg, Russia. Chakchir OB; Nanobiotechnology Laboratory, Saint Petersburg National Research Academic University of the Russian Academy of Science, Saint Petersburg, Russia. Eliseev IE; Nanobiotechnology Laboratory, Saint Petersburg National Research Academic University of the Russian Academy of Science, Saint Petersburg, Russia. Grinchuk TM; Laboratory of Intracellular Signaling, Institute of Cytology of the Russian Academy of Science, Saint Petersburg, Russia. Shamova OV; Laboratory of Design and Synthesis of Biologically Active Peptides, Department of General Pathology and Pathophysiology, FSBSI Institute of Experimental Medicine, Saint Petersburg, Russia.
[Myocardial Contractile Function in Patients with Liver Cirrhosis and Syndrome of Bacterial Overgrowth Syndrome].
Autorzy :
Ivashkin KV; Sechenov First Moscow State Medical University (Sechenov University). Shirokova EN; Sechenov First Moscow State Medical University (Sechenov University). Ivashkin VT; Sechenov First Moscow State Medical University (Sechenov University). Plyusnin SV; 3rd Central Military Clinical Hospital named after A. A. Vishnevsky. ZharkovaMS; Sechenov First Moscow State Medical University (Sechenov University). Maslennikov RV; Sechenov First Moscow State Medical University (Sechenov University). Skhirtladze MR; Sechenov First Moscow State Medical University (Sechenov University). Maevskaya MV; Sechenov First Moscow State Medical University (Sechenov University).
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Źródło :
Kardiologiia [Kardiologiia] 2019 Apr 17; Vol. 59 (4), pp. 67-73. Date of Electronic Publication: 2019 Apr 17.
Differential diagnosis of ascites in internal medicine: clinical case.
Autorzy :
Tikhonov IN; Scientific Research Department of Innovative Therapy of the Scientific and Technological Park of Biomedicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia.; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. ZharkovaMS; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Maevskaya MV; The Department of Propaedeutics of Internal Medicine of the Faculty of Physiology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Zozulya VN; The Department of Propaedeutics of Internal Medicine of the Faculty of Physiology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Nekrasova TP; Acad. A.I. Strukov Department of Pathological Anatomy, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Arslanyan MG; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Musina NP; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Tatarkina MA; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Rzaev RT; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Puzakov KB; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Ivashkin VT; Scientific Research Department of Innovative Therapy of the Scientific and Technological Park of Biomedicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia.; V.H. Vasilenko Clinic of Propaedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia.; The Department of Propaedeutics of Internal Medicine of the Faculty of Physiology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia. Malikova MS; B.V. Petrovsky Russian Scientific Center of Surgery, Moscow, Russia.
N-domain of angiotensin-converting enzyme hydrolyzes human and rat amyloid-β(1-16) peptides as arginine specific endopeptidase potentially enhancing risk of Alzheimer's disease.
Autorzy :
Kugaevskaya EV; Institute of Biomedical Chemistry, Moscow, Russia. Veselovsky AV; Institute of Biomedical Chemistry, Moscow, Russia. Indeykina MI; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Moscow, Russia.; Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences, Moscow, Russia.; Moscow Institute of Physics and Technology, Dolgoprudnyi, Moscow Region, Russia. Solovyeva NI; Institute of Biomedical Chemistry, Moscow, Russia. ZharkovaMS; Institute of Biomedical Chemistry, Moscow, Russia. Popov IA; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Moscow, Russia.; Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences, Moscow, Russia.; Moscow Institute of Physics and Technology, Dolgoprudnyi, Moscow Region, Russia. Nikolaev EN; Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences, Moscow, Russia.; Moscow Institute of Physics and Technology, Dolgoprudnyi, Moscow Region, Russia.; Skolkovo Institute of Science and technology, Moscow, Russia. Mantsyzov AB; Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, Russia. Makarov AA; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Moscow, Russia. Kozin SA; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Moscow, Russia. .
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Źródło :
Scientific reports [Sci Rep] 2018 Jan 10; Vol. 8 (1), pp. 298. Date of Electronic Publication: 2018 Jan 10.
Minibactenecins ChBac7.Nα and ChBac7. Nβ - Antimicrobial Peptides from Leukocytes of the Goat Capra hircus.
Autorzy :
Shamova OV; Institute of Experimental Medicine, Acad. Pavlov Str. 12, Saint-Petersburg, 197376, Russia ; Saint-Petersburg State University, Universitetskaya Emb, 7/9, Saint-Petersburg, 199034, Russia. Orlov DS; Institute of Experimental Medicine, Acad. Pavlov Str. 12, Saint-Petersburg, 197376, Russia ; Saint-Petersburg State University, Universitetskaya Emb, 7/9, Saint-Petersburg, 199034, Russia. ZharkovaMS; Institute of Experimental Medicine, Acad. Pavlov Str. 12, Saint-Petersburg, 197376, Russia. Balandin SV; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Mikhluho-Maklaya Str. 16/10, Moscow, 117997, Russia. Yamschikova EV; Institute of Experimental Medicine, Acad. Pavlov Str. 12, Saint-Petersburg, 197376, Russia. Knappe D; University of Leipzig, Deutscher Platz 5, D-04103 Leipzig, Germany. Hoffmann R; University of Leipzig, Deutscher Platz 5, D-04103 Leipzig, Germany. Kokryakov VN; Institute of Experimental Medicine, Acad. Pavlov Str. 12, Saint-Petersburg, 197376, Russia ; Saint-Petersburg State University, Universitetskaya Emb, 7/9, Saint-Petersburg, 199034, Russia. Ovchinnikova TV; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Mikhluho-Maklaya Str. 16/10, Moscow, 117997, Russia.
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Źródło :
Acta naturae [Acta Naturae] 2016 Jul-Sep; Vol. 8 (3), pp. 136-146.
[Interaction of novel oxazoline derivatives of 17(20)e-pregna-5,17(20)-diene with cytochrome P450 17A1].
Autorzy :
Stulov SV; Institute of Biomedical Chemistry, Moscow, Russia. Dugin NO; Institute of Biomedical Chemistry, Moscow, Russia. ZharkovaMS; Institute of Biomedical Chemistry, Moscow, Russia. Shcherbinin DS; Institute of Biomedical Chemistry, Moscow, Russia. Kuzikov AV; Institute of Biomedical Chemistry, Moscow, Russia. Shumyantseva VV; Institute of Biomedical Chemistry, Moscow, Russia. Misharin AY; Institute of Biomedical Chemistry, Moscow, Russia. Veselovsky AV; Institute of Biomedical Chemistry, Moscow, Russia.
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