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    Wyświetlanie 1-5 z 5
    Tytuł:
    Anticancer osmium complex inhibitors of the HIF-1α and p300 protein-protein interaction.
    Autorzy:
    Yang C; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Wang W; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Li GD; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Zhong HJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Dong ZZ; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Wong CY; Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, China.
    Kwong DW; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Ma DL; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Leung CH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
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    Źródło:
    Scientific reports [Sci Rep] 2017 Feb 22; Vol. 7, pp. 42860. Date of Electronic Publication: 2017 Feb 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Coordination Complexes/*chemical synthesis
    E1A-Associated p300 Protein/*metabolism
    Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
    Osmium/*chemistry
    Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Cell Line ; Coordination Complexes/chemistry ; Coordination Complexes/pharmacology ; Dose-Response Relationship, Drug ; E1A-Associated p300 Protein/chemistry ; HEK293 Cells ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/chemistry ; Mice ; Molecular Structure ; Phosphorylation/drug effects ; Protein Binding/drug effects ; Signal Transduction/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Development of a luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of adenosine.
    Autorzy:
    Lu L; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Zhong HJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    He B; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Leung CH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Ma DL; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.; Partner State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Hong Kong, China.
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    Źródło:
    Scientific reports [Sci Rep] 2016 Jan 18; Vol. 6, pp. 19368. Date of Electronic Publication: 2016 Jan 18.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Adenosine*
    Biosensing Techniques*
    Coordination Complexes*/chemistry
    G-Quadruplexes*
    Iridium*
    Luminescence*
    Luminescent Measurements ; Molecular Structure
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes.
    Autorzy:
    Lu L; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Zhong HJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Wang M; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Ho SL; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Li HW; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Leung CH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Ma DL; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
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    Źródło:
    Scientific reports [Sci Rep] 2015 Sep 30; Vol. 5, pp. 14619. Date of Electronic Publication: 2015 Sep 30.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Luminescent Agents*
    Amyloid beta-Peptides/*metabolism
    Iridium/*pharmacology
    Protein Aggregates/*drug effects
    Protein Aggregation, Pathological/*metabolism
    Amyloid beta-Peptides/chemistry ; Animals ; Cell Line, Tumor ; Cell Survival ; Humans ; Iridium/chemistry ; Mice ; Molecular Structure ; Neuroblastoma ; Neurons/metabolism ; Neurons/pathology ; Protein Aggregation, Pathological/drug therapy
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Identification of an iridium(III) complex with anti-bacterial and anti-cancer activity.
    Autorzy:
    Lu L; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Liu LJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Chao WC; Department of Biomedical Science and Environmental Biology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
    Zhong HJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Wang M; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Chen XP; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Lu JJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
    Li RN; Department of Biomedical Science and Environmental Biology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
    Ma DL; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
    Leung CH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
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    Źródło:
    Scientific reports [Sci Rep] 2015 Sep 29; Vol. 5, pp. 14544. Date of Electronic Publication: 2015 Sep 29.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anti-Bacterial Agents/*chemistry
    Antineoplastic Agents/*chemistry
    Coordination Complexes/*chemistry
    Iridium/*chemistry
    Organometallic Compounds/*chemistry
    Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/pharmacology ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Coordination Complexes/chemical synthesis ; Coordination Complexes/pharmacology ; Dose-Response Relationship, Drug ; Drug Design ; Enterococcus faecalis/drug effects ; Enterococcus faecalis/growth & development ; Escherichia coli/drug effects ; Escherichia coli/growth & development ; Humans ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/growth & development ; Ligands ; Microbial Sensitivity Tests ; Organometallic Compounds/chemical synthesis ; Organometallic Compounds/pharmacology ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/growth & development
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Facile microwave-assisted synthesis of Klockmannite CuSe nanosheets and their exceptional electrical properties.
    Autorzy:
    Liu YQ; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 215123 Suzhou, P. R. China.
    Wang FX; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 215123 Suzhou, P. R. China.
    Xiao Y; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 215123 Suzhou, P. R. China.
    Peng HD; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 215123 Suzhou, P. R. China.
    Zhong HJ; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 215123 Suzhou, P. R. China.
    Liu ZH; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 215123 Suzhou, P. R. China.
    Pan GB; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 215123 Suzhou, P. R. China.
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    Źródło:
    Scientific reports [Sci Rep] 2014 Aug 08; Vol. 4, pp. 5998. Date of Electronic Publication: 2014 Aug 08.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-5 z 5

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