- Tytuł:
- Vanillic Acid Suppresses HIF-1α Expression via Inhibition of mTOR/p70S6K/4E-BP1 and Raf/MEK/ERK Pathways in Human Colon Cancer HCT116 Cells.
- Autorzy:
- Źródło:
- International journal of molecular sciences [Int J Mol Sci] 2019 Jan 22; Vol. 20 (3). Date of Electronic Publication: 2019 Jan 22.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Extracellular Signal-Regulated MAP Kinases/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Ribosomal Protein S6 Kinases, 70-kDa/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Vanillic Acid/*therapeutic use
raf Kinases/*metabolism
Animals ; Cell Proliferation/drug effects ; HCT116 Cells ; Humans ; Immunohistochemistry ; MAP Kinase Signaling System/drug effects ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neovascularization, Pathologic/drug therapy
Czasopismo naukowe