Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Zidovudine"" wg kryterium: Temat


Tytuł :
Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery.
Autorzy :
Krakovka S; Department of Cell and Molecular Biology, BMC, Uppsala University, Uppsala, Sweden.
Ranjbarian F; Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden.
Luján LA; Centro de Investigación y Desarrollo en Immunología y Enfermedades Infecciosas (CIDIE), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)/Universidad Católica de Córdoba (UCC), Cordoba, Argentina.
Saura A; Centro de Investigación y Desarrollo en Immunología y Enfermedades Infecciosas (CIDIE), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)/Universidad Católica de Córdoba (UCC), Cordoba, Argentina.
Larsen NB; Statens Serum Institut, København S, Denmark.
Jiménez-González A; Department of Cell and Molecular Biology, BMC, Uppsala University, Uppsala, Sweden.
Reggenti A; Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden.
Luján HD; Centro de Investigación y Desarrollo en Immunología y Enfermedades Infecciosas (CIDIE), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)/Universidad Católica de Córdoba (UCC), Cordoba, Argentina.
Svärd SG; Department of Cell and Molecular Biology, BMC, Uppsala University, Uppsala, Sweden. Electronic address: .
Hofer A; Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden. Electronic address: .
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2022 Jun; Vol. 298 (6), pp. 102028. Date of Electronic Publication: 2022 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Replication*
Giardia lamblia*/enzymology
Giardia lamblia*/genetics
Protozoan Proteins*/antagonists & inhibitors
Protozoan Proteins*/genetics
Thymidine Kinase*/antagonists & inhibitors
Thymidine Kinase*/genetics
Zidovudine*/pharmacology
Animals ; Drug Discovery ; Gerbillinae ; Giardiasis/drug therapy ; Metronidazole/therapeutic use ; Thymidine
Czasopismo naukowe
Tytuł :
Fevipiprant (QAW039) does not affect the pharmacokinetics of zidovudine, its glucuronide, and penicillin G via inhibition of UGT2B7 and/or OAT3.
Autorzy :
Kulkarni S; Novartis Institutes for Biomedical Research, East Hanover, NJ, USA. Electronic address: .
Poller B; Novartis Institutes for Biomedical Research, Basel, Switzerland.
Drollmann A; Novartis Pharma, AG, Basel, Switzerland.
Shah B; Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
Gray C; Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
Greco E; Novartis Pharma, AG, Basel, Switzerland.
Rahmanzadeh G; Novartis Institutes for Biomedical Research, Basel, Switzerland.
Hanna I; Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
Weiss HM; Novartis Institutes for Biomedical Research, Basel, Switzerland.
Pokaż więcej
Źródło :
Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2022 Feb; Vol. 72, pp. 102097. Date of Electronic Publication: 2021 Nov 17.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucuronides*
Zidovudine*
Indoleacetic Acids ; Penicillin G ; Pyridines ; Receptors, Prostaglandin
Raport
Tytuł :
Zidovudine inhibits telomere elongation, increases the transposable element LINE-1 copy number and compromises mouse embryo development.
Autorzy :
Navarro PA; Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY, USA. .; Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 3900 Bandeirantes Avenue, Ribeirão Preto, São Paulo, 14049-900, Brazil. .
Wang F; Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY, USA.
Pimentel R; Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY, USA.
Robinson LG Jr; Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY, USA.
Berteli TS; Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY, USA.; Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 3900 Bandeirantes Avenue, Ribeirão Preto, São Paulo, 14049-900, Brazil.
Keefe DL; Department of Obstetrics and Gynecology, NYU Langone Medical Center, New York, NY, USA.
Pokaż więcej
Źródło :
Molecular biology reports [Mol Biol Rep] 2021 Dec; Vol. 48 (12), pp. 7767-7773. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji :
Journal Article
MeSH Terms :
RNA-Binding Proteins/*genetics
Telomere/*metabolism
Zidovudine/*pharmacology
Animals ; Anti-HIV Agents/pharmacology ; Blastocyst/drug effects ; DNA Transposable Elements/genetics ; Embryonic Development/drug effects ; Female ; HIV Infections/drug therapy ; HIV Infections/genetics ; Long Interspersed Nucleotide Elements/genetics ; Long Interspersed Nucleotide Elements/physiology ; Mice/embryology ; Models, Animal ; Oocytes/drug effects ; Pregnancy ; RNA-Binding Proteins/metabolism ; Reverse Transcriptase Inhibitors/pharmacology ; Telomere/drug effects ; Zidovudine/adverse effects ; Zidovudine/metabolism ; Zygote/drug effects
Czasopismo naukowe
Tytuł :
Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers - antiherpes activity and penetration behavior across the human vaginal epithelium.
Autorzy :
Szymańska E; Department of Pharmaceutical Technology, Medical University of Białystok, Bialystok, Poland.
Krzyżowska M; Department of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg, Sweden.; Military Institute of Hygiene and Epidemiology, Warsaw, Poland.
Cal K; Department of Pharmaceutical Technology, Medical University of Gdańsk, Gdańsk, Poland.
Mikolaszek B; Department of Pharmaceutical Technology, Medical University of Gdańsk, Gdańsk, Poland.
Tomaszewski J; Private Obstetric and Gynecological Clinic, Tomaszewski Medical Centre, Białystok, Poland.
Wołczyński S; Department of Reproduction and Gynecological Endocrinology, Medical University of Białystok, Bialystok, Poland.
Winnicka K; Department of Pharmaceutical Technology, Medical University of Białystok, Bialystok, Poland.
Pokaż więcej
Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 2278-2288.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacology
Herpes Labialis/*drug therapy
Nanoparticles/*chemistry
Vagina/*drug effects
Zidovudine/*pharmacology
Antiviral Agents/administration & dosage ; Antiviral Agents/pharmacokinetics ; Chitosan/chemistry ; Drug Carriers/chemistry ; Female ; Glutamic Acid/chemistry ; Humans ; Keratinocytes ; Technology, Pharmaceutical ; Zidovudine/administration & dosage ; Zidovudine/pharmacokinetics
Czasopismo naukowe
Tytuł :
Enhancement of the transdermal delivery of zidovudine by pretreating the skin with two physical enhancers: microneedles and sonophoresis.
Autorzy :
Martínez-Segoviano IJ; División de Estudios de Posgrado (Tecnología Farmacéutica), Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Av. 1o de Mayo s/n, 54740, Cuautitlán Izcalli, Estado de México, Mexico.
Ganem-Rondero A; División de Estudios de Posgrado (Tecnología Farmacéutica), Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Av. 1o de Mayo s/n, 54740, Cuautitlán Izcalli, Estado de México, Mexico. .
Pokaż więcej
Źródło :
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences [Daru] 2021 Dec; Vol. 29 (2), pp. 279-290. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Skin/*chemistry
Zidovudine/*administration & dosage
Administration, Cutaneous ; Animals ; Molecular Structure ; Needles ; Phonophoresis ; Skin Absorption ; Spectroscopy, Fourier Transform Infrared ; Swine ; Zidovudine/chemistry
Czasopismo naukowe
Tytuł :
Development of Triazoles and Triazolium Salts Based on AZT and Their Anti-Viral Activity against HIV-1.
Autorzy :
de Alencar DM; ITQB-NOVA-Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avd da Republica, 2780-157 Oeiras, Portugal.
Gonçalves J; Human Immunobiology and Pathogenesis Laboratory, Chronic Diseases Research Center, NOVA Medical School, NOVA University of Lisbon, 1150-082 Lisbon, Portugal.
Vieira A; ITQB-NOVA-Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avd da Republica, 2780-157 Oeiras, Portugal.
Cerqueira SA; Human Immunobiology and Pathogenesis Laboratory, Chronic Diseases Research Center, NOVA Medical School, NOVA University of Lisbon, 1150-082 Lisbon, Portugal.
Sebastião C; Human Immunobiology and Pathogenesis Laboratory, Chronic Diseases Research Center, NOVA Medical School, NOVA University of Lisbon, 1150-082 Lisbon, Portugal.
Leitão MIPS; ITQB-NOVA-Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avd da Republica, 2780-157 Oeiras, Portugal.
Francescato G; ITQB-NOVA-Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avd da Republica, 2780-157 Oeiras, Portugal.
Antenori P; ITQB-NOVA-Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avd da Republica, 2780-157 Oeiras, Portugal.
Soares H; Human Immunobiology and Pathogenesis Laboratory, Chronic Diseases Research Center, NOVA Medical School, NOVA University of Lisbon, 1150-082 Lisbon, Portugal.
Petronilho A; ITQB-NOVA-Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avd da Republica, 2780-157 Oeiras, Portugal.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 06; Vol. 26 (21). Date of Electronic Publication: 2021 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Development*
Anti-HIV Agents/*pharmacology
HIV-1/*drug effects
Triazoles/*pharmacology
Zidovudine/*pharmacology
Anti-HIV Agents/chemical synthesis ; Anti-HIV Agents/chemistry ; Microbial Sensitivity Tests ; Molecular Structure ; Salts/chemical synthesis ; Salts/chemistry ; Salts/pharmacology ; Triazoles/chemical synthesis ; Triazoles/chemistry ; Zidovudine/chemical synthesis ; Zidovudine/chemistry
Czasopismo naukowe
Tytuł :
Poor outcome and high prevalence of invasive fungal infections in patients with adult T-cell leukemia/lymphoma exposed to zidovudine and interferon alfa.
Autorzy :
Guery R; Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Suarez F; Service d'Hématologie Adultes, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Lanternier F; Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Bougnoux ME; Laboratoire de Microbiologie Clinique, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Lecuyer H; Laboratoire de Microbiologie Clinique, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Avettand-Fenoel V; Laboratoire de Microbiologie Clinique, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Sibon D; Service d'Hématologie Adultes, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Frenzel L; Service d'Hématologie Adultes, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Raphalen JH; Service de Réanimation, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Helias P; Département de Radiothérapie-Oncologie-Hématologie, Centre Hospitalier Universitaire de La Guadeloupe, Pointe à Pitre, France.
Renaudier P; Service d'Oncologie-Hématologie, Centre Hospitalier Universitaire de La Martinique, Hôpital Pierre Zobda Quitman, Fort de France, France.
Santa F; Centre Hospitalier de Cayenne, Guyane Française, France.
Lecuit M; Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.; Biology of Infection Unit, Institut Pasteur, Inserm U1117, Paris, France.
Lortholary O; Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Hermine O; Service d'Hématologie Adultes, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Aguilar C; Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.
Marçais A; Service d'Hématologie Adultes, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France. .; Laboratoire d'Onco-Hématologie, Institut Necker-Enfants Malades, INSERM U1151, Université de Paris, Paris, France. .
Pokaż więcej
Źródło :
Annals of hematology [Ann Hematol] 2021 Nov; Vol. 100 (11), pp. 2813-2824. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Interferon-alpha/*adverse effects
Invasive Fungal Infections/*etiology
Leukemia-Lymphoma, Adult T-Cell/*drug therapy
Zidovudine/*adverse effects
Adolescent ; Adult ; Aged ; Antibiotic Prophylaxis ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Aspergillosis/epidemiology ; Aspergillosis/etiology ; Febrile Neutropenia/complications ; Female ; Fever of Unknown Origin/epidemiology ; Fever of Unknown Origin/etiology ; Fungemia/epidemiology ; Fungemia/etiology ; Humans ; Interferon-alpha/administration & dosage ; Invasive Fungal Infections/epidemiology ; Kaplan-Meier Estimate ; Leukemia-Lymphoma, Adult T-Cell/complications ; Leukemia-Lymphoma, Adult T-Cell/mortality ; Male ; Middle Aged ; Opportunistic Infections/epidemiology ; Opportunistic Infections/etiology ; Pneumonia, Pneumocystis/epidemiology ; Pneumonia, Pneumocystis/etiology ; Prevalence ; Prognosis ; Retrospective Studies ; Strongyloidiasis/epidemiology ; Strongyloidiasis/etiology ; Strongyloidiasis/prevention & control ; Treatment Outcome ; Young Adult ; Zidovudine/administration & dosage
Czasopismo naukowe
Tytuł :
Zidovudine (azidothymidine, AZT) unexpressed clinical potential against multidrug-resistant Gram-negative isolates.
Autorzy :
Di Bella S; Clinical Department of Medical, Surgical and Health Sciences, Trieste University, Trieste, Italy. Electronic address: .
Luzzati R; Clinical Department of Medical, Surgical and Health Sciences, Trieste University, Trieste, Italy.
Lagatolla C; Department of Life Sciences, Trieste University, Trieste, Italy.
Pokaż więcej
Źródło :
International journal of antimicrobial agents [Int J Antimicrob Agents] 2022 Jan; Vol. 59 (1), pp. 106500. Date of Electronic Publication: 2021 Dec 18.
Typ publikacji :
Letter; Comment
MeSH Terms :
Zidovudine*/pharmacology
Opinia redakcyjna
Tytuł :
Response to Letter to the Editor: "Zidovudine/azidothymidine (AZT) unexpressed clinical potential against multidrug-resistant Gram negatives".
Autorzy :
Foletto VS; Universidade Federal de Santa Maria, Programa de Pós-Graduação em Ciências Farmacêuticas, Santa Maria, RS, Brazil.
da Rosa TF; Universidade Federal de Santa Maria, Programa de Pós-Graduação em Ciências Farmacêuticas, Santa Maria, RS, Brazil.
Serafin MB; Universidade Federal de Santa Maria, Programa de Pós-Graduação em Ciências Farmacêuticas, Santa Maria, RS, Brazil.
Bottega A; Universidade Federal de Santa Maria, Programa de Pós-Graduação em Ciências Farmacêuticas, Santa Maria, RS, Brazil.
Hörner R; Universidade Federal de Santa Maria, Programa de Pós-Graduação em Ciências Farmacêuticas, Santa Maria, RS, Brazil; Universidade Federal de Santa Maria, Departamento de Análises Clínicas e Toxicológicas, Santa Maria, RS, Brazil. Electronic address: .
Pokaż więcej
Źródło :
International journal of antimicrobial agents [Int J Antimicrob Agents] 2022 Jan; Vol. 59 (1), pp. 106501. Date of Electronic Publication: 2021 Dec 18.
Typ publikacji :
Letter; Comment
MeSH Terms :
Anti-HIV Agents*
Zidovudine*
Opinia redakcyjna
Tytuł :
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
Autorzy :
Plyasova AA; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Berrino E; Dipartimento di Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Florence, Italy.
Khan II; Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya Street 6, Moscow 117198, Russia.; N.N. Blokhin Cancer Research Center, Kashirskoe Shosse 24, Moscow 115478, Russia.
Veselovsky AV; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Pokrovsky VS; Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya Street 6, Moscow 117198, Russia.; N.N. Blokhin Cancer Research Center, Kashirskoe Shosse 24, Moscow 115478, Russia.
Angeli A; Dipartimento di Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Florence, Italy.
Ferraroni M; Dipartimento di Chimica 'Ugo Schiff', Università degli Studi di Firenze, Via della Lastruccia 3-13, 50019 Florence, Italy.
Supuran CT; Dipartimento di Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Florence, Italy.
Pokrovskaya MV; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Alexandrova SS; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Gladilina YA; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Sokolov NN; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Hilal A; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Carta F; Dipartimento di Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Florence, Italy.
Zhdanov DD; Institute of Biomedical Chemistry, Pogodinskaya Street 10/8, Moscow 119121, Russia.
Pokaż więcej
Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Aug 12; Vol. 64 (15), pp. 11432-11444. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Carbonic Anhydrases/*metabolism
Enzyme Inhibitors/*pharmacology
Sulfonamides/*pharmacology
Telomerase/*antagonists & inhibitors
Zidovudine/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Female ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Molecular Structure ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Structure-Activity Relationship ; Sulfonamides/chemistry ; Telomerase/metabolism ; Tumor Cells, Cultured ; Zidovudine/chemistry
Czasopismo naukowe
Tytuł :
Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon.
Autorzy :
Abongwa LE; Department of Biological Sciences, Faculty of Science, University of Bamenda, BP 39, Bamenda, North West Region, Cameroon. .; Department of Microbiology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya. .; Chantal Biya International Center for Research on the Prevention and Management of HIV/AIDS (CIRCB), Yaoundé, Cameroon. .
Nyamache AK; Department of Microbiology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya.
Charles F; Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Torimiro J; Chantal Biya International Center for Research on the Prevention and Management of HIV/AIDS (CIRCB), Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Emmanuel N; Baptist Convention Health Board, Mbingo Baptist Hospital, Bamenda, North West Region, Cameroon.
Domkam I; Chantal Biya International Center for Research on the Prevention and Management of HIV/AIDS (CIRCB), Yaoundé, Cameroon.
Eyongetah M; Bamenda Regional Hospital, Bamenda, North West Region, Cameroon.
Jude B; Santa district health centre, Santa, North West Region, Cameroon.
Mua FH; Ndop district health centre, Ndop, North West Region, Cameroon.
Bella S; Ndop district health centre, Ndop, North West Region, Cameroon.
Tamboh TC; Bali District Health Centre, Bali, North West Region, Cameroon.
Moungang EC; Bafut District Hospitals, Bafut, North West Region, Cameroon.
Ngum V; Bafut District Hospitals, Bafut, North West Region, Cameroon.
Okemo P; Department of Microbiology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya.
Pokaż więcej
Źródło :
BMC gastroenterology [BMC Gastroenterol] 2022 Jun 03; Vol. 22 (1), pp. 286. Date of Electronic Publication: 2022 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-HIV Agents*/adverse effects
Chemical and Drug Induced Liver Injury*/drug therapy
Chemical and Drug Induced Liver Injury*/epidemiology
Chemical and Drug Induced Liver Injury*/etiology
HIV Infections*/drug therapy
HIV-1*
Adolescent ; Adult ; Antiretroviral Therapy, Highly Active/adverse effects ; Antiretroviral Therapy, Highly Active/methods ; Cameroon/epidemiology ; Humans ; Lamivudine/adverse effects ; Male ; Middle Aged ; Risk Factors ; Young Adult ; Zidovudine/adverse effects
Czasopismo naukowe
Tytuł :
Acquired HIV drug resistance among adults living with HIV receiving first-line antiretroviral therapy in Rwanda: A cross-sectional nationally representative survey.
Autorzy :
Musengimana G; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Tuyishime E; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Kiromera A; 3489University of Maryland, Center for International Health, Education and Biosecurity, (CIHEB), Baltimore, MD USA.
Malamba SS; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Mulindabigwi A; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Habimana MR; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Baribwira C; 3489University of Maryland, Center for International Health, Education and Biosecurity, (CIHEB), Baltimore, MD USA.
Ribakare M; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Habimana SD; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
DeVos J; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Atlanta, GA USA.
Mwesigwa RCN; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Kayirangwa E; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Rwanda.
Semuhore JM; World Health Organization, Rwanda Office.
Rwibasira GN; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.
Suthar AB; U.S. Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV & TB, Atlanta, GA USA.
Remera E; Ministry of Health, 1242Rwanda Biomedical Center, HIV/AIDs, STIs and OBBI Division, Kigali City, Rwanda.; University of Basel, Basel, Switzerland.; Swiss Tropical and Public Health Institute, Basel, Switzerland.
Pokaż więcej
Źródło :
Antiviral therapy [Antivir Ther] 2022 Jun; Vol. 27 (3), pp. 13596535221102690.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV-1*/genetics
Adult ; Anti-Retroviral Agents/pharmacology ; Anti-Retroviral Agents/therapeutic use ; Cross-Sectional Studies ; Drug Resistance, Viral/genetics ; Humans ; Lamivudine/therapeutic use ; Nevirapine/therapeutic use ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Rwanda/epidemiology ; Viral Load ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial, randomised, non-inferiority trial.
Autorzy :
Paton NI; Infectious Diseases Translational Research Programme and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: nick_.
Musaazi J; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Kityo C; Joint Clinical Research Centre, Kampala, Uganda.
Walimbwa S; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Hoppe A; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Balyegisawa A; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Asienzo J; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Kaimal A; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Mirembe G; Makerere University Walter Reed Project, Kampala, Uganda.
Lugemwa A; Joint Clinical Research Centre, Mbarara, Uganda.
Ategeka G; Joint Clinical Research Centre, Fort Portal, Uganda.
Borok M; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.
Mugerwa H; Joint Clinical Research Centre, Kampala, Uganda.
Siika A; Department of Medicine, Moi University School of Medicine, Eldoret, Kenya.
Odongpiny ELA; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Castelnuovo B; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Kiragga A; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Kambugu A; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Pokaż więcej
Corporate Authors :
NADIA Trial Team
Źródło :
The lancet. HIV [Lancet HIV] 2022 Jun; Vol. 9 (6), pp. e381-e393. Date of Electronic Publication: 2022 Apr 20.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/adverse effects
HIV Infections*/drug therapy
HIV-1*
Darunavir ; Drug Therapy, Combination ; Heterocyclic Compounds, 3-Ring ; Humans ; Lamivudine/adverse effects ; Oxazines ; Piperazines ; Prospective Studies ; Pyridones ; RNA/therapeutic use ; Ritonavir ; Tenofovir ; Viral Load ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
DnaA and SspA regulation of the iraD gene of Escherichia coli: an alternative DNA damage response independent of LexA/RecA.
Autorzy :
Sass TH; Department of Biology, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454-9110, USA.
Ferrazzoli AE; Department of Biology, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454-9110, USA.
Lovett ST; Department of Biology, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454-9110, USA.
Pokaż więcej
Źródło :
Genetics [Genetics] 2022 May 31; Vol. 221 (2).
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
DNA Damage*
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Escherichia coli*/genetics
Escherichia coli*/metabolism
Escherichia coli Proteins*/genetics
Escherichia coli Proteins*/metabolism
DNA Replication ; Gene Expression Regulation, Bacterial ; Hydrogen Peroxide/metabolism ; Rec A Recombinases/metabolism ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Sigma Factor/genetics ; Zidovudine/pharmacology
Czasopismo naukowe
Tytuł :
Improved Hematologic Outcomes in HIV1-Exposed Infants Receiving Nevirapine Compared With Zidovudine for Postnatal Prophylaxis in a High Resource Setting.
Autorzy :
Dollfus C; From the Service d'Hématologie et Oncologie Pédiatrique, Hôpital d'Enfants Armand Trousseau, APHP Sorbonne Université, Paris, France.
Le Chenadec J; CESP1018, INSERM, Service Epidémiologie-Santé Publique, Hôpital Bicêtre, Le Kremlin Bicêtre, France.
Mandelbrot L; Service de Gynécologie-Obstétrique, Hôpital Louis Mourier, APHP Nord Université de Paris, Colombes, France.; INSERM, UMR1137-IAME, Université de Paris, Paris, France.
Tubiana R; Service de Maladies Infectieuses et Tropicales, Hôpital Pitié-Salpêtrière, APHP Sorbonne Université, Paris, France.; INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Université, Paris, France.
Faye A; Service de Pédiatrie Générale, Hôpital Robert Debré, APHP Nord Université de Paris, Paris, France.
Brossard M; CESP1018, INSERM, Service Epidémiologie-Santé Publique, Hôpital Bicêtre, Le Kremlin Bicêtre, France.; APHP, Service de Santé Publique, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Frange P; Service de Microbiologie clinique, Hôpital Necker Enfants-Malades, APHP Centre Université de Paris, Paris, France.; EHU 7328 PACT, Institut Imagine, Université de Paris, Paris, France.
Blanche S; Service d'Immunologie Pédiatrique, Hôpital Necker Enfants Malades, APHP Centre Université de Paris, Paris, France.
Warszawski J; CESP1018, INSERM, Service Epidémiologie-Santé Publique, Hôpital Bicêtre, Le Kremlin Bicêtre, France.; APHP, Service de Santé Publique, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.; Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France; and The ANRS CO1/CO11 study group members are listed in the Acknowledgments.
Pokaż więcej
Corporate Authors :
ANRS CO1/CO11 study group
Źródło :
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2022 May 01; Vol. 41 (5), pp. 420-423.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/prevention & control
Pregnancy Complications, Infectious*/drug therapy
Female ; Humans ; Infant ; Infectious Disease Transmission, Vertical/prevention & control ; Nevirapine/therapeutic use ; Pregnancy ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092.
Autorzy :
Owor M; From the Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Tierney C; Department of Biostatistics, Center for Biostatistics in AIDS Research, Harvard T.H Chan School of Public Health, Boston, MA.
Ziemba L; Department of Biostatistics, Center for Biostatistics in AIDS Research, Harvard T.H Chan School of Public Health, Boston, MA.
Browning R; National Institute of Allergy and Infectious Diseases, Bethesda, MD.
Moye J; NIH/NICHD/DER/MPIDB, Bethesda, MD.
Graham B; Frontier Science Foundation, Amherst, NY.
Reding C; Frontier Science Foundation, Amherst, NY.
Costello D; IMPAACT Laboratory Center, University of California, Los Angeles, CA.
Norman J; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Wiesner L; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Hughes E; Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA.
Whalen ME; Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA.
Purdue L; NIH/NIAID/DAIDS/PAB, Bethesda, MD.
Mmbaga BT; Kilimanjaro Clinical Research Institute-Kilimanjaro Christian Medical Center and Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Kamthunzi P; University of North Carolina Project, Lilongwe, Malawi.
Kawalazira R; College of Medicine, Johns Hopkins Research Project, Blantyre, Malawi.
Nathoo K; College of Health Sciences, University of Zimbabwe, Avondale, Harare, Zimbabwe.
Bradford S; FHI 360, IMPAACT Operations Center, Durham, NC.
Coletti A; FHI 360, IMPAACT Operations Center, Durham, NC.
Aweeka F; Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA.
Musoke P; From the Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.; Department of Paediatrics and Child Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Pokaż więcej
Źródło :
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2021 May 01; Vol. 40 (5), pp. 446-452.
Typ publikacji :
Clinical Trial, Phase IV; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
MeSH Terms :
Anti-HIV Agents/*pharmacokinetics
HIV Infections/*drug therapy
Lamivudine/*pharmacokinetics
Lopinavir/*pharmacokinetics
Ritonavir/*pharmacokinetics
Zidovudine/*pharmacokinetics
Africa South of the Sahara/epidemiology ; Anti-HIV Agents/blood ; Area Under Curve ; Child, Preschool ; Chromatography, Liquid/instrumentation ; Cohort Studies ; Drug Combinations ; Drug Elimination Routes ; Drug-Related Side Effects and Adverse Reactions ; Female ; HIV Infections/complications ; Humans ; Infant ; Lamivudine/blood ; Lopinavir/blood ; Male ; Patient Safety ; Ritonavir/blood ; Severe Acute Malnutrition/complications ; Tandem Mass Spectrometry/instrumentation ; Zidovudine/blood
Czasopismo naukowe
Tytuł :
Targeting Apoptosis Signal-Regulating Kinase-1 (ASK-1) As a Biomarker of Monocrotaline-Induced Pulmonary Hypertension following Administration of Antiretroviral Medications in Rat Model.
Autorzy :
Adeoti AO; Department of Human Physiology, College of Health Sciences, School of Laboratory Medicine and Medical Sciences, University of KwaZulu- Natal, Durban, South Africa.; Department of Medicine, College of Medicine, Ado-Ekiti, Ekiti State, Nigeria.
Nadar A; Department of Human Physiology, College of Health Sciences, School of Laboratory Medicine and Medical Sciences, University of KwaZulu- Natal, Durban, South Africa.
Channa ML; Department of Human Physiology, College of Health Sciences, School of Laboratory Medicine and Medical Sciences, University of KwaZulu- Natal, Durban, South Africa.
Pokaż więcej
Źródło :
West African journal of medicine [West Afr J Med] 2022 Apr 29; Vol. 39 (4), pp. 394-398.
Typ publikacji :
Journal Article; Randomized Controlled Trial, Veterinary
MeSH Terms :
HIV Infections*
Hypertension, Pulmonary*/chemically induced
Hypertension, Pulmonary*/drug therapy
Animals ; Anti-Retroviral Agents ; Apoptosis ; Biomarkers ; Humans ; Male ; Monocrotaline ; Rats ; Rats, Sprague-Dawley ; Ritonavir ; Zidovudine
Czasopismo naukowe
Tytuł :
Zidovudine and lamivudine reach higher concentrations in ventricular than in lumbar human cerebrospinal fluid.
Autorzy :
Eggers C; Department of Neurology, Johannes Kepler University, Linz, Austria.
Hoetelmans R; Clinical Pharmacology & Pharmacometrics, Janssen Pharmaceutica NV, Beerse, Belgium.
Läer S; Institute for Clinical Pharmacy and Pharmacotherapy, University Hospital Düsseldorf, Germany.
Pokaż więcej
Źródło :
AIDS (London, England) [AIDS] 2020 Nov 01; Vol. 34 (13), pp. 1883-1889.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anti-HIV Agents/*cerebrospinal fluid
Anti-HIV Agents/*pharmacokinetics
HIV Infections/*drug therapy
Lamivudine/*cerebrospinal fluid
Lamivudine/*pharmacokinetics
Zidovudine/*cerebrospinal fluid
Zidovudine/*pharmacokinetics
AIDS Dementia Complex/prevention & control ; Adult ; Anti-HIV Agents/blood ; Anti-HIV Agents/therapeutic use ; Drug Therapy, Combination ; HIV Infections/metabolism ; HIV-1/genetics ; Humans ; Lamivudine/blood ; Lamivudine/therapeutic use ; Male ; RNA, Viral/blood ; RNA, Viral/cerebrospinal fluid ; Spinal Puncture ; Stavudine/administration & dosage ; Stavudine/blood ; Stavudine/cerebrospinal fluid ; Stavudine/therapeutic use ; Viral Load ; Zidovudine/blood ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
Influence of maternal use of tenofovir disoproxil fumarate or zidovudine in Vietnamese pregnant women with HIV on infant growth, renal function, and bone health.
Autorzy :
Kinai E; Department of Laboratory Medicine, Tokyo Medical University, Tokyo, Japan.; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Nguyen HDT; National Hospital for Tropical Diseases, Hanoi, Vietnam.
Do HQ; National Hospital of Obstetrics and Gynecology, Hanoi, Vietnam.
Matsumoto S; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Nagai M; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Tanuma J; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Nguyen KV; National Hospital for Tropical Diseases, Hanoi, Vietnam.
Pham TN; National Hospital for Tropical Diseases, Hanoi, Vietnam.
Oka S; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2021 Apr 29; Vol. 16 (4), pp. e0250828. Date of Electronic Publication: 2021 Apr 29 (Print Publication: 2021).
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV Infections/*drug therapy
Maternal Exposure/*adverse effects
Tenofovir/*adverse effects
Zidovudine/*adverse effects
beta 2-Microglobulin/*urine
Body Height/drug effects ; Endopeptidases/blood ; Female ; Humans ; Infant ; Male ; Multivariate Analysis ; Pregnancy ; Pregnant Women ; Prospective Studies ; Tenofovir/therapeutic use ; Vietnam ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
The association between HIV tri-therapy with the development of Type-2 Diabetes Mellitus in a rural South African District: A case-control study.
Autorzy :
Bam NE; Department of Nursing, Walter Sisulu University, Mthatha, South Africa.
Mabunda SA; The George Institute for Global Health, University of New South Wales, Sydney, Australia.
Ntsaba J; Department of Nursing, Walter Sisulu University, Mthatha, South Africa.
Apalata T; Department of Laboratory Medicine, Walter Sisulu University, Mthatha, South Africa.
Nomatshila SC; Department of Public Health, Walter Sisulu University, Mthatha, South Africa.
Chitha W; Health Systems Enablement & Innovation Unit, University of the Witwatersrand, Johannesburg, South Africa.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2020 Dec 31; Vol. 15 (12), pp. e0244067. Date of Electronic Publication: 2020 Dec 31 (Print Publication: 2020).
Typ publikacji :
Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2*/chemically induced
Diabetes Mellitus, Type 2*/epidemiology
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Rural Population*
Stavudine*/administration & dosage
Stavudine*/adverse effects
Zidovudine*/administration & dosage
Zidovudine*/adverse effects
Adult ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; South Africa/epidemiology ; Time Factors
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies