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Wyszukujesz frazę ""Zinc Finger E-box-Binding Homeobox 1"" wg kryterium: Temat


Tytuł :
Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1.
Autorzy :
Jiang H; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Zhou C; Xuanwu Hospital, Capital Medical University, 100053, Beijing, China.
Zhang Z; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Wang Q; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Wei H; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Shi W; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Li J; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Wang Z; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Ou Y; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Wang W; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Wang H; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Zhang Q; Tianjin Key Laboratory of Organ Transplantation, Tianjin First Center Hospital, 300192, Tianjin, China.
Sun W; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China.
Sun P; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Yang S; Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation, Medical College of Nankai University, 300071, Tianjin, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 12; Vol. 11 (1), pp. 5129. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*metabolism
Jagged-1 Protein/*metabolism
Neoplastic Stem Cells/*metabolism
Receptor, Notch1/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Animals ; Breast Neoplasms/genetics ; Cell Line, Tumor ; Female ; Humans ; Jagged-1 Protein/genetics ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; Phenotype ; Receptor, Notch1/genetics ; Tumor Microenvironment ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
ZEB and Snail expression indicates epithelial-mesenchymal transition in canine melanoma.
Autorzy :
Veloso ES; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil.
Gonçalves INN; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil.
Silveira TL; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil.
Espirito Santo JT; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil.
Figueiredo LV; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil.
Varaschin MS; Department of Veterinary Medicine, Federal University of Lavras, MG, Brazil.
Cassali GD; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil.
Del Puerto HL; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil.
Ferreira E; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais, MG, Brazil. Electronic address: .
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Źródło :
Research in veterinary science [Res Vet Sci] 2020 Aug; Vol. 131, pp. 7-14. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Dog Diseases/*metabolism
Epithelial-Mesenchymal Transition/*physiology
Melanoma/*veterinary
Skin Neoplasms/*veterinary
Snail Family Transcription Factors/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Animals ; Cadherins/metabolism ; Cell Adhesion ; Cell Movement ; Dog Diseases/genetics ; Dogs ; Gene Expression Regulation, Neoplastic ; Humans ; Melanoma/metabolism ; Mouth Neoplasms/metabolism ; Mouth Neoplasms/pathology ; Mouth Neoplasms/veterinary ; Skin Neoplasms/metabolism ; Skin Neoplasms/pathology ; Snail Family Transcription Factors/genetics ; Transcription Factors/metabolism ; Tumor Microenvironment ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
PHRF1 promotes migration and invasion by modulating ZEB1 expression.
Autorzy :
Lee JY; Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan.
Fan CC; Department of Superintendent Office, Mackay Memorial Hospital, Taipei, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsinchu, Taiwan.
Chou NL; Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan.
Lin HW; Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan.
Chang MS; Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan.; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
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Źródło :
PloS one [PLoS One] 2020 Jul 30; Vol. 15 (7), pp. e0236876. Date of Electronic Publication: 2020 Jul 30 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*
Lung Neoplasms/*pathology
Membrane Proteins/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Animals ; Apoptosis ; Biomarkers, Tumor ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Membrane Proteins/genetics ; Mice ; Neoplasm Invasiveness ; Prognosis ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
During mitosis ZEB1 "switches" from being a chromatin-bound epithelial gene repressor, to become a microtubule-associated protein.
Autorzy :
Fouani L; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia.
Huang MLH; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia.
Cole L; The iThree Institute, University of Technology Sydney, Broadway, Sydney, New South Wales 2007, Australia.
Jansson PJ; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia.
Kovacevic Z; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia.
Richardson DR; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan; Centre for Cancer Cell Biology, Griffith Institute for Drug Discovery, Griffith University, Nathan, Brisbane, 4111, Queensland, Australia. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2020 Jul; Vol. 1867 (7), pp. 118673. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromatin/*genetics
Microtubule-Associated Proteins/*genetics
Mitosis/*genetics
Zinc Finger E-box-Binding Homeobox 1/*genetics
Cell Cycle Checkpoints/genetics ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p27/genetics ; Cytokinesis/genetics ; Humans ; Microtubule-Associated Proteins/chemistry ; Protein Binding/genetics ; Spindle Apparatus/genetics ; Tubulin/genetics ; Zinc Finger E-box Binding Homeobox 2/genetics ; Zinc Finger E-box-Binding Homeobox 1/chemistry
Czasopismo naukowe
Tytuł :
ZEB1 modulates endometrial receptivity through epithelial-mesenchymal transition in endometrial epithelial cells in vitro.
Autorzy :
Ran J; The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, PR China.
Yang HH; The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, PR China.
Huang HP; The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, PR China.
Huang HL; The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, PR China.
Xu Z; The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, PR China.
Zhang W; The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, PR China; Department of Basic Medicine, School of Medicine, Xiamen University, Xiamen, 361102, PR China. Electronic address: .
Wang ZX; The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, PR China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 May 07; Vol. 525 (3), pp. 699-705. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epithelial-Mesenchymal Transition*
Endometrium/*pathology
Epithelial Cells/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Biomarkers/metabolism ; Cadherins/metabolism ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Embryo Implantation ; Female ; Gene Knockdown Techniques ; Humans ; Menstrual Cycle ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Spheroids, Cellular/metabolism ; Vimentin/metabolism ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
Clonal ZEB1-Driven Mesenchymal Transition Promotes Targetable Oncologic Antiangiogenic Therapy Resistance.
Autorzy :
Chandra A; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Jahangiri A; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Chen W; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Nguyen AT; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Yagnik G; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Pereira MP; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Jain S; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Garcia JH; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Shah SS; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Wadhwa H; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Joshi RS; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Weiss J; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Wolf KJ; Department of Bioengineering, University of California Berkeley, Berkeley, California.
Lin JG; Department of Bioengineering, University of California Berkeley, Berkeley, California.
Müller S; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Rick JW; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Diaz AA; Department of Neurosurgery, University of California San Francisco, San Francisco, California.
Gilbert LA; Department of Urology, University of California San Francisco, San Francisco, California.
Kumar S; Department of Bioengineering, University of California Berkeley, Berkeley, California.
Aghi MK; Department of Neurosurgery, University of California San Francisco, San Francisco, California. .
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Źródło :
Cancer research [Cancer Res] 2020 Apr 01; Vol. 80 (7), pp. 1498-1511. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Brain Neoplasms/*drug therapy
Glioblastoma/*drug therapy
Neoplastic Stem Cells/*drug effects
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Adult ; Aged ; Angiogenesis Inhibitors/therapeutic use ; Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Antineoplastic Agents, Phytogenic/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Bevacizumab/pharmacology ; Bevacizumab/therapeutic use ; Biphenyl Compounds/pharmacology ; Biphenyl Compounds/therapeutic use ; Brain/blood supply ; Brain/pathology ; Brain Neoplasms/blood supply ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Hypoxia/drug effects ; Cell Line, Tumor ; Chitinase-3-Like Protein 1/metabolism ; Drug Resistance, Neoplasm ; Epithelial-Mesenchymal Transition/drug effects ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Glioblastoma/blood supply ; Glioblastoma/genetics ; Glioblastoma/pathology ; Human Umbilical Vein Endothelial Cells ; Humans ; Lignans/pharmacology ; Lignans/therapeutic use ; Male ; Middle Aged ; Neoplasm Invasiveness/pathology ; Neoplasm Invasiveness/prevention & control ; Neoplastic Stem Cells/pathology ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/pathology ; Tumor Microenvironment/drug effects ; Up-Regulation ; Xenograft Model Antitumor Assays ; Young Adult ; Zinc Finger E-box-Binding Homeobox 1/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies.
Autorzy :
Fu R; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Li Y; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Jiang N; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Ren BX; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Zang CZ; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Liu LJ; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Lv WC; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Li HM; State Key Laboratory of Natural Medicines, Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, Nanjing, China.
Weiss S; Life Sciences Institute, Rogel Cancer Center, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Li ZY; Department of Medicinal Chemistry, College of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Lu T; State Key Laboratory of Natural Medicines, Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, Nanjing, China.
Wu ZQ; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2020 Mar 02; Vol. 130 (3), pp. 1252-1270.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Zinc Finger E-box-Binding Homeobox 1/*deficiency
Animals ; Antineoplastic Agents, Immunological/pharmacology ; Cisplatin/pharmacology ; Endothelium/immunology ; Epigenesis, Genetic/drug effects ; Epigenesis, Genetic/immunology ; Gene Deletion ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/immunology ; Mice ; Mice, Transgenic ; Neoplasms, Experimental/blood supply ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/genetics ; Neoplasms, Experimental/immunology ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/immunology ; Zinc Finger E-box-Binding Homeobox 1/immunology
Czasopismo naukowe
Tytuł :
Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate.
Autorzy :
Wang X; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.; Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, China.
Xu H; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Sciences, Kunming, 650223, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Cheng C; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.; Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, China.
Ji Z; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.; Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, China.
Zhao H; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.
Sheng Y; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.
Li X; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.
Wang J; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.
Shu Y; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.
He Y; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.
Fan L; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Dong B; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Xue W; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Wai Chua C; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China.; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Wu D; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Sciences, Kunming, 650223, China.
Gao WQ; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China. .; Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, China. .
He Zhu H; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200127, China. .; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Feb 05; Vol. 11 (1), pp. 706. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Prostate/*cytology
Stem Cells/*physiology
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Animals ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition ; Female ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Nude ; Mice, Transgenic ; Organ Culture Techniques ; Pregnancy ; Prostate/metabolism ; Prostate/pathology ; Prostatic Neoplasms/pathology ; Rats, Sprague-Dawley ; Single-Cell Analysis ; Wnt Signaling Pathway ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
ZEB1 activated-VPS9D1-AS1 promotes the tumorigenesis and progression of prostate cancer by sponging miR-4739 to upregulate MEF2D.
Autorzy :
Wang X; Department of Urology, Carson International Cancer Centre, Shenzhen University General Hospital and Shenzhen University Clinical Medical Academy Centre, Shenzhen University, Shenzhen, 518000, Guangdong, China; College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, China; Health Science Center,School of Medicine, Shenzhen University, Shenzhen, China.
Chen Q; Department of Urology, Weifang Yidu Central Hospital, Weifang, Shandong, China.
Wang X; Department of Plastic Surgery, The First Affiliated Hospital and Clinical Medicine College of Henan University of Science and Technology, China.
Li W; Department of Urology Surgery, The First Affiliated Hospital and Clinical Medicine College of Henan University of Science and Technology, China.
Yu G; Department of Urology Surgery, The First Affiliated Hospital and Clinical Medicine College of Henan University of Science and Technology, China.
Zhu Z; Department of Urology Surgery, The First Affiliated Hospital and Clinical Medicine College of Henan University of Science and Technology, China.
Zhang W; Department of Urology, The Second Affiliated Hospital of Shandong First Medical University, Shandong First Medical University&Shandong Academy of Medicar Sciences, Taian, 271000, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Feb; Vol. 122, pp. 109557. Date of Electronic Publication: 2019 Dec 30.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs/*metabolism
Prostatic Neoplasms/*metabolism
RNA, Long Noncoding/*genetics
RNA, Long Noncoding/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Apoptosis ; Carcinogenesis ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Humans ; MEF2 Transcription Factors/genetics ; MEF2 Transcription Factors/metabolism ; Male ; MicroRNAs/genetics ; Prostatic Neoplasms/genetics ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
The microRNA‑708‑5p/ZEB1/EMT axis mediates the metastatic potential of osteosarcoma.
Autorzy :
Feng T; Key Laboratory of Diagnostic Medicine Designated by The Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
Zhu Z; Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China.
Jin Y; Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
Wang H; Key Laboratory of Diagnostic Medicine Designated by The Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
Mao X; Key Laboratory of Diagnostic Medicine Designated by The Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
Liu D; Key Laboratory of Diagnostic Medicine Designated by The Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
Li Y; Key Laboratory of Diagnostic Medicine Designated by The Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
Lu L; Key Laboratory of Diagnostic Medicine Designated by The Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
Zuo G; Key Laboratory of Diagnostic Medicine Designated by The Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China.
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Źródło :
Oncology reports [Oncol Rep] 2020 Feb; Vol. 43 (2), pp. 491-502. Date of Electronic Publication: 2019 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms/*genetics
Bone Neoplasms/*pathology
MicroRNAs/*genetics
Osteosarcoma/*genetics
Osteosarcoma/*pathology
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Bone Neoplasms/metabolism ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Metastasis ; Osteosarcoma/metabolism ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosis.
Autorzy :
Fu R; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.
Lv WC; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.
Xu Y; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.
Gong MY; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.
Chen XJ; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing, 210009, China.
Jiang N; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.
Xu Y; Department of Orthopedic Surgery, Digital Medicine Institute, The Affiliated Nanjing Hospital of Nanjing Medical University, Nanjing, 210006, China.
Yao QQ; Department of Orthopedic Surgery, Digital Medicine Institute, The Affiliated Nanjing Hospital of Nanjing Medical University, Nanjing, 210006, China.
Di L; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.
Lu T; State Key Laboratory of Natural Medicines, Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, Nanjing, 211198, China.
Wang LM; Department of Orthopedic Surgery, Digital Medicine Institute, The Affiliated Nanjing Hospital of Nanjing Medical University, Nanjing, 210006, China.
Mo R; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing, 210009, China.
Wu ZQ; State Key Laboratory of Natural Medicines, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Jan 23; Vol. 11 (1), pp. 460. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neovascularization, Physiologic/*physiology
Osteogenesis/*physiology
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Adaptor Proteins, Signal Transducing/pharmacology ; Aged ; Animals ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Calcium-Binding Proteins/pharmacology ; Endothelial Cells/metabolism ; Epigenesis, Genetic ; Female ; Humans ; Mice, Knockout ; Mice, Transgenic ; Middle Aged ; Neovascularization, Physiologic/genetics ; Osteogenesis/drug effects ; Osteogenesis/genetics ; Osteoporosis/therapy ; Ovariectomy ; Platelet Endothelial Cell Adhesion Molecule-1/metabolism ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
ZEB1 and ZEB2 gene editing mediated by CRISPR/Cas9 in A549 cell line.
Autorzy :
Mohammadinejad R
Sassan H
Pardakhty A
Hashemabadi M
Ashrafizadeh M
Dehshahri A
Mandegary A
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Źródło :
Bratislavske lekarske listy [Bratisl Lek Listy] 2020; Vol. 121 (1), pp. 31-36.
Typ publikacji :
Journal Article
MeSH Terms :
CRISPR-Cas Systems*
Carcinoma, Non-Small-Cell Lung*/genetics
Gene Editing*/methods
Lung Neoplasms*/genetics
Zinc Finger E-box Binding Homeobox 2*/genetics
Zinc Finger E-box-Binding Homeobox 1*/genetics
A549 Cells ; Gene Knockout Techniques ; Humans
Czasopismo naukowe
Tytuł :
LncRNA SPRY4‑IT1 promotes progression of osteosarcoma by regulating ZEB1 and ZEB2 expression through sponging of miR‑101 activity.
Autorzy :
Yao H; Department of Orthopaedics, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China.
Hou G; Department of Orthopaedics, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China.
Wang QY; Department of Orthopaedics, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China.
Xu WB; Department of Orthopaedics, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China.
Zhao HQ; Department of Orthopaedics, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China.
Xu YC; Department of Orthopaedics, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China.
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Źródło :
International journal of oncology [Int J Oncol] 2020 Jan; Vol. 56 (1), pp. 85-100. Date of Electronic Publication: 2019 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*metabolism
Bone Neoplasms/*pathology
MicroRNAs/*genetics
Osteosarcoma/*pathology
RNA, Long Noncoding/*genetics
Zinc Finger E-box Binding Homeobox 2/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Cell Proliferation ; Disease Progression ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, Inbred BALB C ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Signal Transduction ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; Zinc Finger E-box Binding Homeobox 2/genetics ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
Circular RNA circ-PVT1 contributes to paclitaxel resistance of gastric cancer cells through the regulation of ZEB1 expression by sponging miR-124-3p.
Autorzy :
Liu YY; Department of General Surgery, Yantaishan Hospital, China.
Zhang LY; Department of Pharmacy, Weihai Stomatological Hospital, China.
Du WZ; Department of Gastroenterology, Yantai YEDA Hospital, China.
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Źródło :
Bioscience reports [Biosci Rep] 2019 Dec 20; Vol. 39 (12).
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Neoplasm*
MicroRNAs/*metabolism
Neoplasm Proteins/*metabolism
Paclitaxel/*pharmacology
RNA, Circular/*metabolism
RNA, Neoplasm/*metabolism
Stomach Neoplasms/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Cell Line, Tumor ; Female ; Humans ; Male ; MicroRNAs/genetics ; Neoplasm Proteins/genetics ; RNA, Circular/genetics ; RNA, Neoplasm/genetics ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
LncRNA ZEB1-AS1 down-regulation suppresses the proliferation and invasion by inhibiting ZEB1 expression in oesophageal squamous cell carcinoma.
Autorzy :
Zhao Y; Department of Medical Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
Wang N; Henan Academy of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China.
Zhang X; Department of Medical Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
Liu H; College of Life Sciences, Zhengzhou University, Zhengzhou, China.
Yang S; Department of Medical Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Dec; Vol. 23 (12), pp. 8206-8218. Date of Electronic Publication: 2019 Oct 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Down-Regulation*
Gene Expression Regulation, Neoplastic*
Cell Proliferation/*genetics
Esophageal Neoplasms/*genetics
Esophageal Squamous Cell Carcinoma/*genetics
RNA, Long Noncoding/*genetics
Zinc Finger E-box-Binding Homeobox 1/*genetics
Animals ; Cell Line, Tumor ; Cell Movement/genetics ; Epithelial-Mesenchymal Transition/genetics ; Esophageal Neoplasms/metabolism ; Esophageal Neoplasms/therapy ; Esophageal Squamous Cell Carcinoma/metabolism ; Esophageal Squamous Cell Carcinoma/therapy ; Female ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness ; RNA Interference ; RNAi Therapeutics/methods ; Xenograft Model Antitumor Assays/methods ; Zinc Finger E-box-Binding Homeobox 1/metabolism
Czasopismo naukowe
Tytuł :
Hypoxia-induced HIF-1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF-β-dependent EMT.
Autorzy :
Yoshimoto S; Section of Pathology, Division of Biomedical Sciences, Department of Morphological Biology, Fukuoka Dental College, Fukuoka, Japan.
Tanaka F; Division of Oral and Medical Management, Department of Oral and Maxillofacial Surgery, Fukuoka Dental College, Fukuoka, Japan.
Morita H; Department of General Dentistry, Fukuoka Dental College, Fukuoka, Japan.
Hiraki A; Division of Oral and Medical Management, Department of Oral and Maxillofacial Surgery, Fukuoka Dental College, Fukuoka, Japan.
Hashimoto S; Section of Pathology, Division of Biomedical Sciences, Department of Morphological Biology, Fukuoka Dental College, Fukuoka, Japan.
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Źródło :
Cancer medicine [Cancer Med] 2019 Dec; Vol. 8 (18), pp. 7822-7832. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ameloblastoma/*genetics
Ameloblastoma/*metabolism
Cell Transformation, Neoplastic/*genetics
Epithelial-Mesenchymal Transition/*genetics
Hypoxia/*genetics
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Transforming Growth Factor beta/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*genetics
Adolescent ; Adult ; Aged ; Ameloblastoma/pathology ; Cell Line, Tumor ; Cell Transformation, Neoplastic/metabolism ; Female ; Gene Expression Profiling ; Humans ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Immunohistochemistry ; Male ; Middle Aged ; Young Adult ; Zinc Finger E-box-Binding Homeobox 1/metabolism
Czasopismo naukowe
Tytuł :
ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells.
Autorzy :
de Barrios O; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
Sanchez-Moral L; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
Cortés M; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
Ninfali C; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
Profitós-Pelejà N; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
Martínez-Campanario MC; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
Siles L; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.
Del Campo R; Dept of Microbiology, Hospital Ramon y Cajal Health Research Institute (IRYCIS), Spanish Network of Infectious Diseases (REIPI), National Health Institute Carlos III (ISCIII), Madrid, Spain.
Fernández-Aceñero MJ; Dept of Pathology, Hospital Gregorio Marañón, Madrid, Spain.
Darling DS; Dept of Oral Immunology and Infectious Diseases and Center for Genetics and Molecular Medicine, University of Louisville, Louisville, Kentucky, USA.
Castells A; Dept of Gastroenterology, Hospital Clínic and IDIBAPS, Barcelona, Spain.; Gastrointestinal and Pancreatic Oncology Team, CIBERehd, Barcelona, Spain.
Maurel J; Group of Translational Genomics and Targeted Therapeutics in Solid Tumours, Dept of Medical Oncology, Hospital Clínic and IDIBAPS, Barcelona, Spain.
Salas A; Dept of Gastroenterology, Hospital Clínic and IDIBAPS, Barcelona, Spain.
Dean DC; Dept of Ophthalmology and Visual Sciences and Birth Defects Center, University of Louisville, Louisville, Kentucky, USA.; Molecular Targets Program, James G. Brown Cancer Center, Louisville, Kentucky, USA.
Postigo A; Group of Transcriptional Regulation of Gene Expression, Dept of Oncology and Hematology, IDIBAPS, Barcelona, Spain.; Molecular Targets Program, James G. Brown Cancer Center, Louisville, Kentucky, USA.; ICREA, Barcelona, Spain.
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Źródło :
Gut [Gut] 2019 Dec; Vol. 68 (12), pp. 2129-2141. Date of Electronic Publication: 2019 Jul 31.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Neoplasms, Experimental*
Colitis, Ulcerative/*genetics
Colonic Neoplasms/*genetics
DNA Glycosylases/*genetics
Epithelial Cells/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*genetics
Animals ; Biopsy ; Cells, Cultured ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/metabolism ; Colonic Neoplasms/etiology ; Colonic Neoplasms/pathology ; DNA Glycosylases/metabolism ; DNA Repair ; Epithelial Cells/pathology ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; RNA, Neoplasm/genetics ; Zinc Finger E-box-Binding Homeobox 1/metabolism ; Zinc Fingers
Czasopismo naukowe
Tytuł :
Mesenchymal stemlike cells in glioblastoma.
Autorzy :
Tran AN; Department of Neurosurgery, Northwestern University, Chicago, Illinois.
Horbinski C; Department of Neurosurgery, Northwestern University, Chicago, Illinois.; Department of Pathology, Northwestern University, Chicago, Illinois.
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Źródło :
Neuro-oncology [Neuro Oncol] 2020 Oct 14; Vol. 22 (10), pp. 1409-1410.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Brain Neoplasms*
Glioblastoma*
Humans ; Neoplastic Stem Cells ; Zinc Finger E-box-Binding Homeobox 1
Czasopismo naukowe
Tytuł :
MicroRNA-708 prevents ethanol-induced hepatic lipid accumulation and inflammatory reaction via direct targeting ZEB1.
Autorzy :
Hu S; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Liu YM; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Chen-Chen; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Li LY; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Zhang BY; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Yang JF; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Li HD; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Meng XM; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Jun-Li; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.
Xu T; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China. Electronic address: .
Zhou H; National Drug Clinical Trial Center, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118147. Date of Electronic Publication: 2020 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Lipid Metabolism*
Liver/*metabolism
Liver Diseases, Alcoholic/*genetics
MicroRNAs/*genetics
Zinc Finger E-box-Binding Homeobox 1/*genetics
3' Untranslated Regions ; Adult ; Aged ; Cell Line ; Down-Regulation ; Female ; Humans ; Liver/pathology ; Liver Diseases, Alcoholic/metabolism ; Liver Diseases, Alcoholic/pathology ; Male ; Middle Aged ; Up-Regulation
Czasopismo naukowe
Tytuł :
circ_KIAA1429 accelerates hepatocellular carcinoma advancement through the mechanism of m A-YTHDF3-Zeb1.
Autorzy :
Wang M; Department of Radiotherapy, Jiaozhou Central Hospital of Qingdao, Qingdao, China.
Yang Y; Department of Orthopeadic Trauma, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Yang J; Department of Chemotherapy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Yang J; Department of Radiotherapy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Han S; Department of Chemotherapy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Sep 15; Vol. 257, pp. 118082. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*pathology
Liver Neoplasms/*pathology
RNA-Binding Proteins/*genetics
Zinc Finger E-box-Binding Homeobox 1/*genetics
Animals ; Carcinoma, Hepatocellular/genetics ; Cell Line, Tumor ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Liver Neoplasms/genetics ; Mice ; Mice, Nude ; Microarray Analysis ; RNA, Circular/genetics ; Up-Regulation ; Xenograft Model Antitumor Assays
Czasopismo naukowe

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