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    Tytuł:
    REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway.
    Autorzy:
    Zhang H; Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Pathology, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada.; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
    Corredor ALG; Department of Pathology, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada.
    Messina-Pacheco J; Department of Pathology, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada.
    Li Q; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY, USA.
    Zogopoulos G; Department of Surgery, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada.
    Kaddour N; Department of Medicine, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada.
    Wang Y; Department of Surgery, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada.
    Shi BY; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
    Gregorieff A; Department of Pathology, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada.
    Liu JL; Department of Medicine, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada. .
    Gao ZH; Department of Pathology, McGill University and the Research Institute of McGill University Health Centre, Montreal, QC, Canada. .
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    Źródło:
    Communications biology [Commun Biol] 2021 Jun 07; Vol. 4 (1), pp. 688. Date of Electronic Publication: 2021 Jun 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Carcinoma, Pancreatic Ductal/*metabolism
    N-Acetylglucosaminyltransferases/*metabolism
    Pancreatic Neoplasms/*metabolism
    Pancreatitis-Associated Proteins/*metabolism
    Animals ; Carcinoma, Pancreatic Ductal/pathology ; Cell Line, Tumor ; Humans ; MAP Kinase Signaling System ; Male ; Metaplasia/metabolism ; Metaplasia/pathology ; Mice, Inbred C57BL ; N-Acetylglucosaminyltransferases/analysis ; Pancreatic Ducts/metabolism ; Pancreatic Ducts/pathology ; Pancreatic Neoplasms/pathology ; Pancreatitis-Associated Proteins/analysis ; Signal Transduction ; Tumor Cells, Cultured ; raf Kinases/metabolism ; ras Proteins/metabolism ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    ELEMENT TRIAL: study protocol for a randomized controlled trial on endoscopic ultrasound-guided biliary drainage of first intent with a lumen-apposing metal stent vs. endoscopic retrograde cholangio-pancreatography in the management of malignant distal biliary obstruction.
    Autorzy:
    Chen YI; Division of Gastroenterology and Hepatology, McGill University Health Centre, McGill University, Montreal, QC, Canada. .
    Callichurn K; Division of Gastroenterology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
    Chatterjee A; Division of Gastroenterology and Hepatology, Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
    Desilets E; Division of Gastroenterology, Hôpital Charles-Le Moyne, University of Sherbrooke, Greenfield Park, QC, Canada.
    Fergal D; Division of Gastroenterology and Hepatology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
    Forbes N; Division of Gastroenterology and Hepatology, University of Calgary, Calgary, AB, Canada.
    Gan I; Division of Gastroenterology and Hepatology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
    Kenshil S; Division of Gastroenterology and Hepatology, Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
    Khashab MA; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, MD, USA.
    Kunda R; Department of Surgery, Department of Gastroenterology and Hepatology, Department of Advanced Interventional Endoscopy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
    Lam E; Division of Gastroenterology and Hepatology, St-Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
    May G; Division of Gastroenterology and Hepatology, St-Michael's Hospital, University of Toronto, Toronto, ON, Canada.
    Mohamed R; Division of Gastroenterology and Hepatology, University of Calgary, Calgary, AB, Canada.
    Mosko J; Division of Gastroenterology and Hepatology, St-Michael's Hospital, University of Toronto, Toronto, ON, Canada.
    Paquin SC; Division of Gastroenterology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
    Sahai A; Division of Gastroenterology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
    Sandha G; Division of Gastroenterology and Hepatology, University of Alberta Hospital, University of Alberta, Edmonton, AB, Canada.
    Teshima C; Division of Gastroenterology and Hepatology, St-Michael's Hospital, University of Toronto, Toronto, ON, Canada.
    Barkun A; Division of Gastroenterology and Hepatology, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Barkun J; Department of Surgery, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Bessissow A; Department of Radiology, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Candido K; Division of Gastroenterology and Hepatology, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Martel M; Division of Gastroenterology and Hepatology, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Miller C; Division of Gastroenterology and Hepatology, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Waschke K; Division of Gastroenterology and Hepatology, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Zogopoulos G; Department of Surgery, McGill University Health Centre, McGill University, Montreal, QC, Canada.
    Wong C; Division of Gastroenterology and Hepatology, Royal Alexandra Hospital, University of Alberta, Edmonton, AB, Canada.
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    Corporate Authors:
    ELEMENT trial and for the Canadian Endoscopic Research Collaborative (CERC)
    Źródło:
    Trials [Trials] 2019 Dec 09; Vol. 20 (1), pp. 696. Date of Electronic Publication: 2019 Dec 09.
    Typ publikacji:
    Clinical Trial Protocol; Journal Article
    MeSH Terms:
    Bile Duct Neoplasms*/complications
    Cholangiopancreatography, Endoscopic Retrograde*/adverse effects
    Cholangiopancreatography, Endoscopic Retrograde*/methods
    Cholestasis*/therapy
    Drainage*/methods
    Endosonography*/methods
    Stents*/adverse effects
    Ultrasonography, Interventional*/methods
    Humans ; Randomized Controlled Trials as Topic ; Single-Blind Method ; Multicenter Studies as Topic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.
    Autorzy:
    Wong C; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
    Chen F; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
    Alirezaie N; McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada.
    Wang Y; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
    Cuggia A; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
    Borgida A; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
    Holter S; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
    Lenko T; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
    Domecq C; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
    Petersen GM; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
    Syngal S; Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Gastroenterology Division, Brigham and Women's Hospital, Harvard Medical Schozol, Boston, Massachusetts, United States of America.
    Brand R; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Rustgi AK; Division of Gastroenterology, Departments of Medicine and Genetics, Pancreatic Cancer Translation Center of Excellence, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
    Cote ML; Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America.
    Stoffel E; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
    Olson SH; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.
    Roberts NJ; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America.; The Sol Goldman Pancreatic Cancer Research Center, Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America.
    Akbari MR; Women's College Hospital Research Institute, Women's College Hospital, Toronto, Ontario, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
    Majewski J; McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada.
    Klein AP; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America.; The Sol Goldman Pancreatic Cancer Research Center, Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America.
    Greenwood CMT; Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.; Gerald Bronfman Department of Oncology, and Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.
    Gallinger S; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
    Zogopoulos G; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
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    Corporate Authors:
    Alzheimer’s Disease Neuroimaging Initiative
    Źródło:
    PLoS genetics [PLoS Genet] 2019 Aug 30; Vol. 15 (8), pp. e1008344. Date of Electronic Publication: 2019 Aug 30 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Genetic Association Studies/*methods
    Pancreatic Neoplasms/*genetics
    Sequence Analysis, DNA/*methods
    Adenocarcinoma/genetics ; Adult ; BRCA2 Protein/genetics ; Carcinoma/genetics ; Female ; Genes, BRCA2 ; Genetic Predisposition to Disease/genetics ; Germ-Line Mutation/genetics ; Humans ; Male ; Middle Aged ; Pancreas/pathology ; Pancreatic Neoplasms/metabolism ; Protein Serine-Threonine Kinases/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.
    Autorzy:
    Poffenberger MC; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Metcalfe-Roach A; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.
    Aguilar E; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Chen J; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Hsu BE; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Medicine, McGill University, Montreal, Quebec H3G 2M1, Canada.
    Wong AH; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Johnson RM; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Genentech, 1 DNA Way South, San Francisco, CA 94080, USA.
    Flynn B; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Samborska B; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.
    Ma EH; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Gravel SP; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Faculty of Pharmacy, University of Montreal, Montreal, Quebec H3C 3J7, Canada.
    Tonelli L; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.
    Devorkin L; Trev and Joyce Deeley Research Centre, BC Cancer Agency, Victoria, British Columbia V8R 6V5, Canada.
    Kim P; Trev and Joyce Deeley Research Centre, BC Cancer Agency, Victoria, British Columbia V8R 6V5, Canada.
    Hall A; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Research Institute of the McGill University Health Centre, Montreal, Quebec H3H 2R9, Canada.
    Izreig S; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Loginicheva E; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Beauchemin N; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Siegel PM; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Medicine, McGill University, Montreal, Quebec H3G 2M1, Canada.
    Artyomov MN; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Human Immunology and Immunotherapy Programs, Washington University at St. Louis, St. Louis, MO 63110, USA.
    Lum JJ; Trev and Joyce Deeley Research Centre, BC Cancer Agency, Victoria, British Columbia V8R 6V5, Canada.; Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 2Y2, Canada.
    Zogopoulos G; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Research Institute of the McGill University Health Centre, Montreal, Quebec H3H 2R9, Canada.
    Blagih J; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
    Jones RG; Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada. .; Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.; Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2018 Jul 27; Vol. 361 (6400), pp. 406-411.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Adenomatous Polyps/*genetics
    Peutz-Jeghers Syndrome/*genetics
    Protein Serine-Threonine Kinases/*genetics
    Stomach Neoplasms/*genetics
    T-Lymphocytes/*immunology
    AMP-Activated Protein Kinases ; Adenomatous Polyps/immunology ; Adenomatous Polyps/pathology ; Animals ; Chemokine CXCL2/genetics ; Gene Deletion ; Gene Expression ; Humans ; Inflammation/genetics ; Inflammation/immunology ; Inflammation/pathology ; Interleukin-11/genetics ; Interleukin-6/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Peutz-Jeghers Syndrome/immunology ; Peutz-Jeghers Syndrome/pathology ; STAT3 Transcription Factor/metabolism ; Signal Transduction ; Stomach Neoplasms/immunology ; Stomach Neoplasms/pathology
    SCR Disease Name:
    Polyposis, Gastric
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Establishing a clinic-based pancreatic cancer and periampullary tumour research registry in Quebec.
    Autorzy:
    Smith AL; The Research Institute of the McGill University Health Centre, Montreal, QC. ; The Goodman Cancer Research Centre, McGill University, Montreal, QC.
    Bascuñana C; The Research Institute of the McGill University Health Centre, Montreal, QC. ; The Goodman Cancer Research Centre, McGill University, Montreal, QC.
    Hall A; The Research Institute of the McGill University Health Centre, Montreal, QC. ; The Goodman Cancer Research Centre, McGill University, Montreal, QC.
    Salman A; The Research Institute of the McGill University Health Centre, Montreal, QC. ; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC.
    Andrei AZ; The Research Institute of the McGill University Health Centre, Montreal, QC. ; The Goodman Cancer Research Centre, McGill University, Montreal, QC.
    Volenik A; The Research Institute of the McGill University Health Centre, Montreal, QC. ; The Goodman Cancer Research Centre, McGill University, Montreal, QC. ; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, QC.
    Rothenmund H; The Research Institute of the McGill University Health Centre, Montreal, QC. ; The Goodman Cancer Research Centre, McGill University, Montreal, QC. ; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, QC.
    Ferland D; The Research Institute of the McGill University Health Centre, Montreal, QC. ; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC.
    Lamoussenery D; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC. ; Hepato-Pancreato-Biliary Oncology, McGill University Health Centre, Montreal, QC.
    Kamath AS; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC.
    Amre R; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Caglar D; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Gao ZH; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Haegert DG; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Kanber Y; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Michel RP; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Omeroglu-Altinel G; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Asselah J; Hepato-Pancreato-Biliary Oncology, McGill University Health Centre, Montreal, QC.
    Bouganim N; Hepato-Pancreato-Biliary Oncology, McGill University Health Centre, Montreal, QC.
    Kavan P; Hepato-Pancreato-Biliary Oncology, McGill University Health Centre, Montreal, QC.
    Arena G; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC.
    Barkun J; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC.
    Chaudhury P; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC.
    Gallinger S; The Research Institute of the McGill University Health Centre, Montreal, QC.
    Foulkes WD; The Research Institute of the McGill University Health Centre, Montreal, QC. ; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, QC.
    Omeroglu A; Department of Pathology, McGill University Health Centre, Montreal, QC.
    Metrakos P; The Research Institute of the McGill University Health Centre, Montreal, QC. ; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC.
    Zogopoulos G; The Research Institute of the McGill University Health Centre, Montreal, QC. ; The Goodman Cancer Research Centre, McGill University, Montreal, QC. ; Hepato-Pancreato-Biliary and Transplant Surgery, McGill University Health Centre, Montreal, QC. ; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, QC.
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    Źródło:
    Current oncology (Toronto, Ont.) [Curr Oncol] 2015 Apr; Vol. 22 (2), pp. 113-21.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Germline EPHB2 receptor variants in familial colorectal cancer.
    Autorzy:
    Zogopoulos G; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
    Jorgensen C
    Bacani J
    Montpetit A
    Lepage P
    Ferretti V
    Chad L
    Selvarajah S
    Zanke B
    Hudson TJ
    Pawson T
    Gallinger S
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2008 Aug 06; Vol. 3 (8), pp. e2885. Date of Electronic Publication: 2008 Aug 06.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genetic Variation*
    Germ-Line Mutation*
    Colorectal Neoplasms/*genetics
    Receptor, EphB2/*genetics
    Adenomatous Polyposis Coli/genetics ; Base Sequence ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; DNA, Neoplasm/genetics ; DNA, Neoplasm/isolation & purification ; Exons ; Female ; Humans ; Male ; Pedigree ; Polymorphism, Single Nucleotide ; Reference Values ; Registries
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.
    Autorzy:
    Zanke BW; Cancer Care Ontario, 620 University Avenue, Toronto, Ontario M5G 1L7, Canada.
    Greenwood CM
    Rangrej J
    Kustra R
    Tenesa A
    Farrington SM
    Prendergast J
    Olschwang S
    Chiang T
    Crowdy E
    Ferretti V
    Laflamme P
    Sundararajan S
    Roumy S
    Olivier JF
    Robidoux F
    Sladek R
    Montpetit A
    Campbell P
    Bezieau S
    O'Shea AM
    Zogopoulos G
    Cotterchio M
    Newcomb P
    McLaughlin J
    Younghusband B
    Green R
    Green J
    Porteous ME
    Campbell H
    Blanche H
    Sahbatou M
    Tubacher E
    Bonaiti-Pellié C
    Buecher B
    Riboli E
    Kury S
    Chanock SJ
    Potter J
    Thomas G
    Gallinger S
    Hudson TJ
    Dunlop MG
    Pokaż więcej
    Źródło:
    Nature genetics [Nat Genet] 2007 Aug; Vol. 39 (8), pp. 989-94. Date of Electronic Publication: 2007 Jul 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 8*
    Genetic Predisposition to Disease*
    Polymorphism, Single Nucleotide*
    Colorectal Neoplasms/*genetics
    Case-Control Studies ; Chromosome Mapping ; Humans ; Linkage Disequilibrium ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-7 z 7

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