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    Wyświetlanie 1-2 z 2
    Tytuł:
    Improving the specificity of nucleic acid detection with endonuclease-actuated degradation.
    Autorzy:
    Zou RS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Gavrilov M; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
    Liu Y; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Rasoloson D; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Howard Hughes Medical Institute, Baltimore, MD, USA.
    Conte M; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Hardick J; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Shen L; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Chen S; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Pekosz A; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
    Seydoux G; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Howard Hughes Medical Institute, Baltimore, MD, USA.
    Manabe YC; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Ha T; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA. .; Howard Hughes Medical Institute, Baltimore, MD, USA. .
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    Źródło:
    Communications biology [Commun Biol] 2022 Mar 31; Vol. 5 (1), pp. 290. Date of Electronic Publication: 2022 Mar 31.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    COVID-19*/diagnosis
    Molecular Diagnostic Techniques*/methods
    Nucleic Acid Amplification Techniques*/methods
    Nucleic Acids*/isolation & purification
    DNA ; Endonucleases ; Humans ; SARS-CoV-2/genetics
    SCR Protocol:
    LAMP assay
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Very fast CRISPR on demand.
    Autorzy:
    Liu Y; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD, USA. .
    Zou RS; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. .
    He S; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD, USA.
    Nihongaki Y; Department of Cell Biology, Johns Hopkins University, Baltimore, MD, USA.
    Li X; Department of Cell Biology, Johns Hopkins University, Baltimore, MD, USA.
    Razavi S; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. .
    Wu B; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD, USA. .; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USA.; The Center for Cell Dynamics, Johns Hopkins University, Baltimore, MD, USA.
    Ha T; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD, USA. .; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.; Howard Hughes Medical Institute, Baltimore, MD, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2020 Jun 12; Vol. 368 (6496), pp. 1265-1269.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    CRISPR-Associated Protein 9*
    CRISPR-Cas Systems*
    DNA Cleavage/*radiation effects
    DNA Repair/*genetics
    Gene Editing/*methods
    Single-Cell Analysis/*methods
    DNA Breaks, Double-Stranded ; HEK293 Cells ; Histones/metabolism ; Humans ; Light ; MRE11 Homologue Protein/genetics ; Optical Imaging/methods ; Phosphorylation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-2 z 2

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