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Tytuł:
Familiar observers attenuate surgery-induced neuroinflammation and cognitive dysfunction in mice.
Autorzy:
Jiang Q; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.; Department of Anesthesiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Guo M; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.; Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14351. Date of Electronic Publication: 2023 Jul 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Cognitive Dysfunction*/etiology
Postoperative Cognitive Complications*
Mice ; Male ; Animals ; Neuroinflammatory Diseases ; Mice, Inbred C57BL ; Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Late surgical start time is associated with increased blood transfusion following gastric bypass surgery.
Autorzy:
Knio ZO; Department of Anesthesiology, University of Virginia Health, Charlottesville, VA, United States of America.
Zhang L; Department of Anesthesiology, University of Virginia Health, Charlottesville, VA, United States of America.
Watts DA; School of Medicine, University of Virginia, Charlottesville, VA, United States of America.
Zuo Z; Department of Anesthesiology, University of Virginia Health, Charlottesville, VA, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Feb 24; Vol. 18 (2), pp. e0282139. Date of Electronic Publication: 2023 Feb 24 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Gastric Bypass*/adverse effects
Humans ; Retrospective Studies ; Risk Factors ; Risk Assessment ; Treatment Outcome ; Blood Transfusion ; Postoperative Complications/etiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pioglitazone attenuates ischaemic stroke aggravation by blocking PPARγ reduction and inhibiting chronic inflammation in diabetic mice.
Autorzy:
Guo Y; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zuo W; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yin L; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Gu T; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Wang S; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Fang Z; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Wang B; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Dong H; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Hou W; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.
Deng J; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2022 Sep; Vol. 56 (6), pp. 4948-4961. Date of Electronic Publication: 2022 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Ischemia*/drug therapy
Diabetes Mellitus, Experimental*/complications
Ischemic Stroke*
Stroke*/complications
Animals ; Inflammation/complications ; Inflammation/drug therapy ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein ; PPAR gamma/metabolism ; Pioglitazone/pharmacology ; Pioglitazone/therapeutic use ; Tumor Necrosis Factor-alpha ; Vascular Remodeling
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Far infrared light irradiation enhances Aβ clearance via increased exocytotic microglial ATP and ameliorates cognitive deficit in Alzheimer's disease-like mice.
Autorzy:
Li Q; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China.; Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Peng J; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China.
Luo Y; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China.
Zhou J; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China.
Li T; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China.
Cao L; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China.
Peng S; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, VA, 22901, USA. .; Department of Anesthesiology, University of Virginia Health System, 1 Hospital Drive, PO Box 800710, Charlottesville, VA, 22908-0710, USA. .
Wang Z; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 YanJiang West Road, Guangzhou, 510289, Guangdong Province, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2022 Jun 14; Vol. 19 (1), pp. 145. Date of Electronic Publication: 2022 Jun 14.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/genetics
Cognitive Dysfunction*/etiology
Cognitive Dysfunction*/metabolism
Cognitive Dysfunction*/therapy
Adenosine Triphosphate/pharmacology ; Amyloid beta-Peptides/metabolism ; Animals ; Cognition ; Disease Models, Animal ; Mammals/metabolism ; Mice ; Mice, Transgenic ; Microglia/metabolism ; Phosphatidylinositol 3-Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice.
Autorzy:
Min J; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.; Department of Anesthesiology, First Affiliated Hospital, Nanchang University, Nanchang, China.
Lai Z; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.; Department of Anesthesiology, Fujian Medical University Union Hospital, Fuzhou, China.
Wang H; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.; Department of Anesthesiology, General Hospital of Ningxia Medical University, Yinchuan, China.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2022 Apr; Vol. 28 (4), pp. 619-629. Date of Electronic Publication: 2021 Dec 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Adhesion Molecules, Neuronal*/metabolism
Isoflurane*/metabolism
Postoperative Cognitive Complications*/prevention & control
Animals ; Epigenesis, Genetic ; Hippocampus/metabolism ; Male ; Maze Learning ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Sox2 in Learning, Memory, and Postoperative Cognitive Dysfunction in Mice.
Autorzy:
Gui L; Department of Anesthesiology, University of Virginia, Charlottesville, VA 22901, USA.; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Luo Z; Department of Anesthesiology, University of Virginia, Charlottesville, VA 22901, USA.; Department of Anesthesiology, West China Hospital, Sichuan University, No. 37 Guo Xue Alley, Chengdu 610041, China.
Shan W; Department of Anesthesiology, University of Virginia, Charlottesville, VA 22901, USA.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, VA 22901, USA.
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Źródło:
Cells [Cells] 2021 Mar 24; Vol. 10 (4). Date of Electronic Publication: 2021 Mar 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Memory*/drug effects
Postoperative Cognitive Complications/*metabolism
Postoperative Cognitive Complications/*physiopathology
SOXB1 Transcription Factors/*metabolism
Animals ; Gene Silencing ; Male ; Mice, Inbred C57BL ; Resveratrol/pharmacology ; Sirtuin 1/metabolism ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Perioperative Dexmedetomidine attenuates brain ischemia reperfusion injury possibly via up-regulation of astrocyte Connexin 43.
Autorzy:
Zheng X; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, People's Republic of China.
Cai X; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, People's Republic of China.
Ye F; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, People's Republic of China.
Li Y; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, People's Republic of China.
Wang Q; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-Sen University, No. 74 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, People's Republic of China.
Zuo Z; Department of Anesthesiology, University of Virginia, 1 Hospital Drive, PO Box 800710, Charlottesville, Virginia, 22908-0710, USA.
Huang W; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, People's Republic of China. .
Wang Z; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, People's Republic of China. .
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Źródło:
BMC anesthesiology [BMC Anesthesiol] 2020 Dec 07; Vol. 20 (1), pp. 299. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Ischemia/*drug therapy
Connexin 43/*drug effects
Dexmedetomidine/*pharmacology
Hypnotics and Sedatives/*pharmacology
Perioperative Care/*methods
Reperfusion Injury/*drug therapy
Animals ; Astrocytes/drug effects ; Brain Ischemia/genetics ; Connexin 43/genetics ; Disease Models, Animal ; Male ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/genetics ; Up-Regulation/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Novel Individual-based Determination of Postoperative Cognitive Dysfunction in Mice.
Autorzy:
Zhong J; 1Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.; 2Department of Anesthesiology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Li J; 1Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.
Miao C; 2Department of Anesthesiology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Zuo Z; 1Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.
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Źródło:
Aging and disease [Aging Dis] 2020 Oct 01; Vol. 11 (5), pp. 1133-1145. Date of Electronic Publication: 2020 Oct 01 (Print Publication: 2020).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Learning and memory dysfunction of non-surgery cage-mates of mice with surgery.
Autorzy:
Zheng Y; Department of Anesthesiology, University of Virginia, Charlottesville, VA, USA.; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, VA, USA.
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Źródło:
Stress (Amsterdam, Netherlands) [Stress] 2020 Jul; Vol. 23 (4), pp. 474-480. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cognitive Dysfunction*
Stress, Psychological*
Animals ; Cytokines/metabolism ; Hippocampus/metabolism ; Humans ; Learning ; Maze Learning ; Memory ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of inflammation on brain subcellular energetics in anesthetized rats.
Autorzy:
Thiele RH; Department of Anesthesiology, University of Virginia School of Medicine, P.O. Box 800710, Charlottesville, VA, 22908-0710, USA. .
Osuru HP; Department of Anesthesiology, University of Virginia School of Medicine, P.O. Box 800710, Charlottesville, VA, 22908-0710, USA.
Paila U; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, USA.
Ikeda K; Department of Anesthesiology, University of Virginia School of Medicine, P.O. Box 800710, Charlottesville, VA, 22908-0710, USA.
Zuo Z; Department of Anesthesiology, University of Virginia School of Medicine, P.O. Box 800710, Charlottesville, VA, 22908-0710, USA.
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Źródło:
BMC neuroscience [BMC Neurosci] 2019 Jul 15; Vol. 20 (1), pp. 34. Date of Electronic Publication: 2019 Jul 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Brain/*metabolism
Inflammation/*metabolism
Isoflurane/*administration & dosage
Propofol/*administration & dosage
Typhlitis/*metabolism
Adenosine Diphosphate/metabolism ; Adenosine Triphosphate/metabolism ; Anesthetics, Inhalation ; Animals ; Electron Transport Complex IV/metabolism ; HSP90 Heat-Shock Proteins/metabolism ; Heme Oxygenase (Decyclizing)/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Isoflurane/pharmacology ; Lactic Acid/metabolism ; Male ; NF-kappa B/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Propofol/pharmacology ; Protein Carbonylation/drug effects ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A response to readers' comments.
Autorzy:
Zuo Z; Department of Anesthesiology, Sun-Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China. .; Laboratory of RNA and Major Diseases of Brain and Heart, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, Guangzhou, China. .; Department of Anesthesiology, University of Virginia, Charlottesville, VA, 22908, USA. .
Wang Z; Department of Anesthesiology, Sun-Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China.
Meng S; Department of Anesthesiology, Sun-Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China.
Peng S; Department of Anesthesiology, Sun-Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China.
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2018 Sep 14; Vol. 15 (1), pp. 267. Date of Electronic Publication: 2018 Sep 14.
Typ publikacji:
Letter
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice.
Autorzy:
Liang P; Department of Anesthesiology, University of Virginia, Charlottesville, VA, 22901, USA.; Department of Anesthesiology and Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Center, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Shan W; Department of Anesthesiology, University of Virginia, Charlottesville, VA, 22901, USA.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, VA, 22901, USA. .; Department of Anesthesiology and Laboratory of RNA and Major Diseases of Brain and Heart, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 512012, Guangdong, China. .; Department of Anesthesiology, University of Virginia Health System, 1 Hospital Drive, PO Box 800710, Charlottesville, VA, 22908-0710, USA. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2018 Aug 22; Vol. 15 (1), pp. 235. Date of Electronic Publication: 2018 Aug 22.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Bacterial Agents/*administration & dosage
Cefazolin/*administration & dosage
Cognition Disorders/*etiology
Cognition Disorders/*prevention & control
Colitis/*chemically induced
Postoperative Complications/*physiopathology
Animals ; Anti-Bacterial Agents/metabolism ; Brain/drug effects ; Brain/metabolism ; Cefazolin/metabolism ; Cell Line ; Conditioning, Classical/drug effects ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Fear/drug effects ; Fear/physiology ; Interleukins/metabolism ; Laparotomy/adverse effects ; Male ; Maze Learning/drug effects ; Mice ; Microglia/drug effects ; RNA, Ribosomal, 16S/genetics ; RNA, Ribosomal, 16S/metabolism ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment.
Autorzy:
Wang Z; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China.
Meng S; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China.
Cao L; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China.
Chen Y; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China.
Zuo Z; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China. .; Laboratory of RNA and Major Diseases of Brain and Heart, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China. .; Department of Anesthesiology, University of Virginia, Charlottesville, USA. .
Peng S; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510289, Guangdong, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2018 Apr 17; Vol. 15 (1), pp. 109. Date of Electronic Publication: 2018 Apr 17.
Typ publikacji:
Journal Article
MeSH Terms:
Aging*
Cognitive Dysfunction/*metabolism
Inflammation/*pathology
Microglia/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Signal Transduction/*physiology
Amino Acid Chloromethyl Ketones/therapeutic use ; Anesthetics, Inhalation/toxicity ; Animals ; Caspase 1/metabolism ; Cell Line, Transformed ; Cognitive Dysfunction/chemically induced ; Cognitive Dysfunction/drug therapy ; Cysteine Proteinase Inhibitors/therapeutic use ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Inflammation/chemically induced ; Inflammation/drug therapy ; Isoflurane/toxicity ; Male ; Maze Learning/drug effects ; Mice ; Mice, Inbred C57BL ; Microglia/drug effects ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hydrochlorothiazide modulates ischemic heart failure-induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats.
Autorzy:
Luo J; Department of Cardiology, First Affiliated Hospital, Zhong-Shan University, Guangzhou, China.; Department of Geriatrics, Huizhou Municipal Central Hospital, Guangdong, China.
Chen X; Department of Cardiology, First Affiliated Hospital, Zhong-Shan University, Guangzhou, China.
Luo C; Department of Cardiology, First Affiliated Hospital, Zhong-Shan University, Guangzhou, China.
Lu G; Department of Cardiology, First Affiliated Hospital, Zhong-Shan University, Guangzhou, China.
Peng L; Department of Cardiology, First Affiliated Hospital, Zhong-Shan University, Guangzhou, China.
Gao X; Department of Cardiology, First Affiliated Hospital, Zhong-Shan University, Guangzhou, China.
Zuo Z; Department of Anesthesiology, University of Virginia Health System, Charlottesville, VA, USA.
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Źródło:
Cardiovascular therapeutics [Cardiovasc Ther] 2017 Apr; Vol. 35 (2).
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Angiotensin II Type 1 Receptor Blockers/*pharmacology
Diuretics/*pharmacology
Heart Failure/*drug therapy
Heart Ventricles/*drug effects
Hydrochlorothiazide/*pharmacology
Receptor, Angiotensin, Type 1/*drug effects
Ventricular Function, Left/*drug effects
Ventricular Remodeling/*drug effects
Aldosterone/blood ; Angiotensin II/blood ; Animals ; Animals, Newborn ; Cells, Cultured ; Disease Models, Animal ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Fibrosis ; Furosemide/pharmacology ; Heart Failure/metabolism ; Heart Failure/pathology ; Heart Failure/physiopathology ; Heart Ventricles/metabolism ; Heart Ventricles/pathology ; Heart Ventricles/physiopathology ; Male ; Rats, Sprague-Dawley ; Receptor, Angiotensin, Type 1/metabolism ; Recovery of Function ; Signal Transduction/drug effects ; Smad2 Protein/metabolism ; Stroke Volume/drug effects ; Transforming Growth Factor beta1/metabolism ; Valsartan/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Maternal Exposure of Rats to Isoflurane during Late Pregnancy Impairs Spatial Learning and Memory in the Offspring by Up-Regulating the Expression of Histone Deacetylase 2.
Autorzy:
Luo F; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.
Hu Y; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.; Department of Anesthesiology, Jiangxi Province Traditional Chinese Medicine Hospital, Nanchang 33006, China.
Zhao W; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.
Zuo Z; Department of Anesthesiology, University of Virginia, Charlottesville, VA, 22908, United States of America.
Yu Q; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.
Liu Z; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.
Lin J; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.
Feng Y; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.
Li B; Department of Anesthesiology, Jiangxi Province Tumor Hospital, Nanchang 330006, China.
Wu L; Department of Anesthesiology, Jiangxi Province Tumor Hospital, Nanchang 330006, China.
Xu L; Department of Anesthesiology, the First Affiliated Hospital, Nanchang University, Nanchang 33006, China.
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Źródło:
PloS one [PLoS One] 2016 Aug 18; Vol. 11 (8), pp. e0160826. Date of Electronic Publication: 2016 Aug 18 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Anesthetics, Inhalation/*adverse effects
Histone Deacetylase 2/*genetics
Isoflurane/*adverse effects
Maternal Exposure/*adverse effects
Memory/*drug effects
Prenatal Exposure Delayed Effects/*chemically induced
Spatial Learning/*drug effects
Animals ; Female ; Maze Learning/drug effects ; Pregnancy ; Prenatal Exposure Delayed Effects/genetics ; Prenatal Exposure Delayed Effects/physiopathology ; Rats ; Rats, Sprague-Dawley ; Up-Regulation/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1α via CD64/PI3k/Akt and MAPK/ERK signaling pathways.
Autorzy:
Chen J; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120, People's Republic of China.; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
Gu Z; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120, People's Republic of China.; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
Wu M; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120, People's Republic of China.; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
Yang Y; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120, People's Republic of China.; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
Zhang J; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120, People's Republic of China.; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
Ou J; Division of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, People's Republic of China.; Guangdong Province Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, 510080, People's Republic of China.
Zuo Z; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.; Department of Anesthesiology, University of Virginia, Health Science Center, Charlottesville, VA, USA.
Wang J; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China. dr_.; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120, People's Republic of China. dr_.; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China. dr_.
Chen Y; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China. .; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120, People's Republic of China. .; Laboratory of RNA and Major Disease of Brain and Heart, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2016 Aug 16; Vol. 7 (1), pp. 114. Date of Electronic Publication: 2016 Aug 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adipose Tissue/*metabolism
C-Reactive Protein/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Neovascularization, Pathologic/*metabolism
Signal Transduction/*physiology
Stem Cells/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Adipose Tissue/pathology ; Animals ; Cell Proliferation/physiology ; MAP Kinase Signaling System/physiology ; Male ; Matrix Metalloproteinase 2/metabolism ; Mice ; Mice, Inbred C57BL ; Neovascularization, Pathologic/pathology ; Paracrine Communication/physiology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, IgG/metabolism ; Stem Cells/pathology ; Up-Regulation/physiology ; Vasa Vasorum/metabolism ; Vasa Vasorum/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Isoflurane Post-Treatment Improves Outcome after an Embolic Stroke in Rabbits.
Autorzy:
Chen F; Department of Anesthesiology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Long Z; Department of Anesthesiology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Yin J; Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Zuo Z; Department of Anesthesiology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.; Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, United States of America.
Li H; Department of Anesthesiology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
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Źródło:
PloS one [PLoS One] 2015 Dec 08; Vol. 10 (12), pp. e0143931. Date of Electronic Publication: 2015 Dec 08 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anesthetics, Inhalation/*administration & dosage
Cerebral Infarction/*therapy
Embolism/*therapy
Isoflurane/*administration & dosage
Animals ; Cerebral Infarction/complications ; Embolism/complications ; Male ; Rabbits ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Doxepin and imipramine but not fluoxetine reduce the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes.
Autorzy:
Park HJ; Dasom anesthesia and analgesia practice association, Seoul, Republic of Korea. .
Baik HJ; Department of anesthesiology and pain medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea. .
Kim DY; Department of anesthesiology and pain medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea. .
Lee GY; Department of anesthesiology and pain medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea. .
Woo JH; Department of anesthesiology and pain medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea. .
Zuo Z; Department of Anesthesiology, University of Virginia Health System, Charlottesville, VA, USA. .
Chung RK; Department of anesthesiology and pain medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea. .
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Źródło:
BMC anesthesiology [BMC Anesthesiol] 2015 Aug 08; Vol. 15, pp. 116. Date of Electronic Publication: 2015 Aug 08.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Doxepin/*pharmacology
Excitatory Amino Acid Transporter 3/*antagonists & inhibitors
Fluoxetine/*pharmacology
Imipramine/*pharmacology
Animals ; Antidepressive Agents/administration & dosage ; Antidepressive Agents/pharmacology ; Dose-Response Relationship, Drug ; Doxepin/administration & dosage ; Female ; Fluoxetine/administration & dosage ; Glutamic Acid/metabolism ; Imipramine/administration & dosage ; Oocytes/drug effects ; Oocytes/metabolism ; Protein Kinase C/metabolism ; RNA, Messenger/metabolism ; Rats ; Tetradecanoylphorbol Acetate/pharmacology ; Xenopus laevis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Neonatal exposure to sevoflurane may not cause learning and memory deficits and behavioral abnormality in the childhood of Cynomolgus monkeys.
Autorzy:
Zhou L; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Wang Z; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Zhou H; Department of Obstetrics and Gynecology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Liu T; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Lu F; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Wang S; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Li J; Department of Obstetrics and Gynecology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Peng S; Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Zuo Z; 1] Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China [2] Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, U.S.A.
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Źródło:
Scientific reports [Sci Rep] 2015 Jun 05; Vol. 5, pp. 11145. Date of Electronic Publication: 2015 Jun 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Behavior, Animal/*drug effects
Learning/*drug effects
Memory/*drug effects
Methyl Ethers/*pharmacology
Anesthetics, Inhalation/pharmacology ; Animals ; Animals, Newborn ; Cerebral Cortex/drug effects ; Cerebral Cortex/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Macaca fascicularis ; Male ; Sevoflurane
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sevoflurane postconditioning provides neuroprotection against brain hypoxia-ischemia in neonatal rats.
Autorzy:
Ren X; Department of Anesthesiology, The First Hospital of China Medical University, Shenyang, 110001, People's Republic of China.
Wang Z
Ma H
Zuo Z
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2014 Sep; Vol. 35 (9), pp. 1401-4. Date of Electronic Publication: 2014 Apr 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypoxia-Ischemia, Brain/*prevention & control
Methyl Ethers/*administration & dosage
Neuroprotective Agents/*administration & dosage
Analysis of Variance ; Animals ; Animals, Newborn ; Body Weight/drug effects ; Decanoic Acids/pharmacology ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Female ; Hydroxy Acids/pharmacology ; Male ; Potassium Channel Blockers/pharmacology ; Rats ; Rats, Sprague-Dawley ; Sevoflurane
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 27

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