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Wyszukujesz frazę ""a549 cells"" wg kryterium: Temat


Tytuł:
Hibiscus manihot L. flower extract induces anticancer activity through modulation of apoptosis and autophagy in A549 cells.
Autorzy:
Xu M; School of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang, 453-003, Henan, China.
Zhao M; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Zhu M; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Yuan H; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Li Z; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Yan P; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Ma C; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Zhao H; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Wang S; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Wan R; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China.
Wang L; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China. .
Yu G; State Key Laboratory of Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, Institute of Biomedical Science, College of Life Science, Henan Normal university, 46 Jianshe Road, Xinxiang, 453007, Henan, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 06; Vol. 14 (1), pp. 8102. Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:
Journal Article
MeSH Terms:
Hibiscus*/metabolism
Manihot*/metabolism
Lung Neoplasms*/pathology
Humans ; A549 Cells ; Autophagy ; Flowers/metabolism ; Apoptosis ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
IRF1 Mediates Growth Arrest and the Induction of a Secretory Phenotype in Alveolar Epithelial Cells in Response to Inflammatory Cytokines IFNγ/TNFα.
Autorzy:
Recchia Luciani G; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Barilli A; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Visigalli R; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Sala R; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Dall'Asta V; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Rotoli BM; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Azetidines*
Cytokines*/metabolism
Purines*
Pyrazoles*
Sulfonamides*
Tumor Necrosis Factor-alpha*/metabolism
Alveolar Epithelial Cells/metabolism ; Cellular Senescence ; Interleukin-6/metabolism ; Phenotype ; A549 Cells ; Humans
Czasopismo naukowe
Tytuł:
ABCG2 transporter reduces protein aggregation in cigarette smoke condensate-exposed A549 lung cancer cells.
Autorzy:
Ajenu EO; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
Seideneck AM; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
Pandellapalli E; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
Shinsky EM; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
Humphries CL; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
Aparicio NL; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
Sharma M; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
Marden JH; Department of Biology, Penn State University, University Park, Pennsylvania, United states of America.
Krasilnikova MM; Department of Biochemistry and Molecular Biology, Penn State University, University Park, Pennsylvania, United states of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 05; Vol. 19 (3), pp. e0297661. Date of Electronic Publication: 2024 Mar 05 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
ATP Binding Cassette Transporter, Subfamily G, Member 2*/metabolism
Cigarette Smoking*
Lung Neoplasms*
Protein Aggregates*
Humans ; A549 Cells
Czasopismo naukowe
Tytuł:
TonEBP/NFAT5 expression is associated with cisplatin resistance and migration in macrophage-induced A549 cells.
Autorzy:
Song HJ; Department of Physiology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Kim YH; Department of Physiology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Choi HN; Department of Physiology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Kim T; Department of Physiology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Kim SJ; Department of Physiology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Kang MW; Department of thoracic surgery, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
Lee SD; Department of Physiology, Chungnam National University College of Medicine, Daejeon, Republic of Korea. .
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Źródło:
BMC molecular and cell biology [BMC Mol Cell Biol] 2024 Mar 04; Vol. 25 (1), pp. 6. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Cisplatin*/pharmacology
Lung Neoplasms*/drug therapy
Humans ; NF-kappa B ; A549 Cells ; Transcription Factors
Czasopismo naukowe
Tytuł:
Coronavirus M Protein Trafficking in Epithelial Cells Utilizes a Myosin Vb Splice Variant and Rab10.
Autorzy:
Lapierre LA; Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Nashville VA Medical Center, Nashville, TN 37212, USA.
Roland JT; Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Manning EH; Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Nashville VA Medical Center, Nashville, TN 37212, USA.
Caldwell C; Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Nashville VA Medical Center, Nashville, TN 37212, USA.
Glenn HL; Biodesign Institute Center for Immunotherapy, Vaccines & Virotherapy, Tempe, AZ 85287, USA.
Vidalain PO; Equipe Infections Virales, Métabolisme et Immunité, Centre International de Recherche en Infectiologie (CIRI), Univ. Lyon, INSERM U1111, CNRS UMR5308, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, 69008 Lyon, France.; Unité Génomique Virale et Vaccination, Institut Pasteur, CNRS UMR3569, 75015 Paris, France.
Tangy F; Viral Genomics and Vaccination Unit, Department of Virology, Institut Pasteur, CNRS UMR3569, 75015 Paris, France.
Hogue BG; Biodesign Institute Center for Immunotherapy, Vaccines & Virotherapy, Tempe, AZ 85287, USA.; Center for Applied Structural Discovery, Biodesign Institute, Tempe, AZ 85287, USA.; School of Life Sciences, Arizona State University, Phoenix, AZ 85004, USA.
de Haan CAM; Faculty of Veterinary Medicine, Department of Biomolecular Health Sciences, Division of Infectious Diseases and Immunology, Section Virology, University of Utrecht, 3584 CS Utrecht, The Netherlands.
Goldenring JR; Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Nashville VA Medical Center, Nashville, TN 37212, USA.; Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
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Źródło:
Cells [Cells] 2024 Jan 10; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Coronavirus M Proteins*
Animals ; Dogs ; Humans ; Madin Darby Canine Kidney Cells/metabolism ; Madin Darby Canine Kidney Cells/virology ; Middle East Respiratory Syndrome Coronavirus ; Myosins ; rab GTP-Binding Proteins/genetics ; Saccharomyces cerevisiae ; Swine ; Viral Matrix Proteins ; SARS-CoV-2/metabolism ; Murine hepatitis virus/metabolism ; A549 Cells/metabolism ; A549 Cells/virology ; Porcine epidemic diarrhea virus/metabolism
Czasopismo naukowe
Tytuł:
Melittin kills A549 cells by targeting mitochondria and blocking mitophagy flux.
Autorzy:
Li X; Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, People's Republic of China.
Li Z; Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, People's Republic of China.
Meng YQ; Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, People's Republic of China.
Qiao H; Department of Oncology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Zhai KR; Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, People's Republic of China.
Li ZQ; Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, People's Republic of China.
Wei SL; Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, People's Republic of China.
Li B; Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, People's Republic of China.
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Źródło:
Redox report : communications in free radical research [Redox Rep] 2023 Dec; Vol. 28 (1), pp. 2284517. Date of Electronic Publication: 2023 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Mitophagy*
Lung Neoplasms*/drug therapy
Lung Neoplasms*/metabolism
Humans ; A549 Cells ; Melitten/pharmacology ; Melitten/metabolism ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/pharmacology ; Mitochondria/metabolism ; Apoptosis ; Membrane Potential, Mitochondrial
Czasopismo naukowe
Tytuł:
Kv3.4 regulates cell migration and invasion through TGF-β-induced epithelial-mesenchymal transition in A549 cells.
Autorzy:
Sim HJ; Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
Kim MR; Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
Song MS; Department of Physiology, College of Medicine, Gyeongsang National University, Jinju, 52727, Korea.
Lee SY; Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 28; Vol. 14 (1), pp. 2309. Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Transforming Growth Factor beta*/pharmacology
Lung Neoplasms*/pathology
Humans ; A549 Cells ; Cell Line, Tumor ; Transforming Growth Factor beta1/pharmacology ; Epithelial-Mesenchymal Transition ; Cell Movement
Czasopismo naukowe
Tytuł:
Protein interaction networks characterizing the A549 cells Klotho transfected are associated with activated pro-apoptotic Bim and suppressed Wnt/β-catenin signaling pathway.
Autorzy:
Matsumoto M; Department of Thoracic Surgery, Nippon Medical School, Tokyo, 113-8602, Japan.
Ogawa N; Department of Thoracic Surgery, Nippon Medical School, Tokyo, 113-8602, Japan.
Fukuda T; Biosys Technologies, Inc, Tokyo, Tokyo, 153-8904, Japan.
Bando Y; Biosys Technologies, Inc, Tokyo, Tokyo, 153-8904, Japan.
Nishimura T; Department of Translational Medicine Informatics, St. Marianna University School of Medicine, Kawasaki, Kanagawa, 216-8511, Japan. .
Usuda J; Department of Thoracic Surgery, Nippon Medical School, Tokyo, 113-8602, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 25; Vol. 14 (1), pp. 2130. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/genetics
Wnt Signaling Pathway*
Animals ; Humans ; Mice ; A549 Cells ; Bcl-2-Like Protein 11/genetics ; Protein Interaction Maps ; Proteome ; Proteomics
Czasopismo naukowe
Tytuł:
The Roles and Regulatory Mechanisms of Tight Junction Protein Cingulin and Transcription Factor Forkhead Box Protein O1 in Human Lung Adenocarcinoma A549 Cells and Normal Lung Epithelial Cells.
Autorzy:
Ishii D; Department of Thoracic Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.; Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Shindo Y; Department of Thoracic Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.; Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Arai W; Department of Thoracic Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Konno T; Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Kohno T; Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Honda K; Department of Thoracic Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.; Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Miyajima M; Department of Thoracic Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Watanabe A; Department of Thoracic Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Kojima T; Department of Cell Science, Institute of Cancer Research, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/metabolism
Adenocarcinoma of Lung*/pathology
Carcinoma, Non-Small-Cell Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/pathology
Forkhead Box Protein O1*/genetics
Forkhead Box Protein O1*/metabolism
Hydroxamic Acids*
Lung Neoplasms*/metabolism
Tight Junction Proteins*/metabolism
Humans ; A549 Cells ; Epithelial Cells/metabolism ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylase Inhibitors/metabolism ; Lung/pathology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Transcriptomic analysis of glucosidase II beta subunit (GluIIß) knockout A549 cells reveals its roles in regulation of cell adhesion molecules (CAMs) and anti-tumor immunity.
Autorzy:
Khaodee W; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Xiyuan G; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.; Public Experimental Technology Center School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, China.
Han MTT; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Tayapiwatana C; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Chiampanichayakul S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.; Cancer Research Unit, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Anuchapreeda S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.; Cancer Research Unit, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Cressey R; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand. .; Cancer Research Unit, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand. .
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Źródło:
BMC genomics [BMC Genomics] 2024 Jan 20; Vol. 25 (1), pp. 82. Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Leukocytes, Mononuclear*
Cell Adhesion Molecules*/genetics
alpha-Glucosidases*
Humans ; A549 Cells ; Gene Expression Profiling ; Cytokines ; Cell Adhesion ; Cell Adhesion Molecule-1
Czasopismo naukowe
Tytuł:
Enhanced Sensitivity of A549 Cells to Doxorubicin with WS 2 and WSe 2 Nanosheets via the Induction of Autophagy.
Autorzy:
Jin W; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.
Yang T; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.
Jia J; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.
Jia J; Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, Guangzhou University, Guangzhou 510006, China.
Zhou X; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.; Hebei Key Laboratory of Analysis and Control of Zoonotic Pathogenic Microorganism, Baoding 071000, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 18; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/pharmacology
Lung Neoplasms*
Humans ; Animals ; Mice ; A549 Cells ; Autophagy ; Epithelial Cells
Czasopismo naukowe
Tytuł:
Asymmetric Synthesis of Saturated and Unsaturated Hydroxy Fatty Acids (HFAs) and Study of Their Antiproliferative Activity.
Autorzy:
Mountanea OG; Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.; Center of Excellence for Drug Design and Discovery, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Mantzourani C; Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.; Center of Excellence for Drug Design and Discovery, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Gkikas D; Center for Basic Research, Biomedical Research Foundation of the Academy of Athens, 4 Soranou Efesiou Str., 11527 Athens, Greece.
Politis PK; Center for Basic Research, Biomedical Research Foundation of the Academy of Athens, 4 Soranou Efesiou Str., 11527 Athens, Greece.; School of Medicine, European University Cyprus, Nicosia 2404, Cyprus.
Kokotos G; Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.; Center of Excellence for Drug Design and Discovery, National and Kapodistrian University of Athens, 15771 Athens, Greece.
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Źródło:
Biomolecules [Biomolecules] 2024 Jan 15; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Fatty Acids, Unsaturated*/pharmacology
Fatty Acids*/pharmacology
Humans ; A549 Cells ; Acetylation ; Chemical Phenomena
Czasopismo naukowe
Tytuł:
Biological Properties of Extracts Obtained from In Vitro Culture of Plectranthus scutellarioides in a Cell Model.
Autorzy:
Kowalczyk T; Department of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland.
Sikora J; Department of Bioinorganic Chemistry, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
Merecz-Sadowska A; Department of Economic and Medical Informatics, University of Lodz, 90-214 Lodz, Poland.; Department of Allergology and Respiratory Rehabilitation, Medical University of Lodz, 90-725 Lodz, Poland.
Kukula-Koch W; Department of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland.
Synowiec E; Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Majda A; Students Research Group, Department of Medical Biology, Medical University of Lodz, 90-151 Lodz, Poland.
Juda D; Students Research Group, Department of Medical Biology, Medical University of Lodz, 90-151 Lodz, Poland.
Śliwiński T; Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Sitarek P; Department of Medical Biology, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 15; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Plectranthus*
Coumaric Acids*
Humans ; A549 Cells ; Anti-Bacterial Agents ; Phytochemicals
Czasopismo naukowe
Tytuł:
Hypoxia Modulates Radiosensitivity and Response to Different Radiation Qualities in A549 Non-Small Cell Lung Cancer (NSCLC) Cells.
Autorzy:
Nisar H; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.; Department of Medical Sciences, Pakistan Institute of Engineering and Applied Sciences (PIEAS), Islamabad 44000, Pakistan.
Labonté FM; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931 Cologne, Germany.
Roggan MD; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Schmitz C; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.
Chevalier F; UMR6252 CIMAP, CEA-CNRS-ENSICAEN-University of Caen Normandy, 14000 Caen, France.
Konda B; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.
Diegeler S; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Baumstark-Khan C; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.
Hellweg CE; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 13; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 13.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/radiotherapy
Lung Neoplasms*/radiotherapy
Humans ; A549 Cells ; Hypoxia ; Radiation Tolerance ; Oxygen ; Ions ; Phosphatidylinositol 3-Kinases ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Global analysis of the abundance of AU-rich mRNAs in response to glucocorticoid treatment.
Autorzy:
Muazzen Z; Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, 11211, Riyadh, Saudi Arabia.
Moghrabi W; Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, 11211, Riyadh, Saudi Arabia.
Bakheet T; Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, 11211, Riyadh, Saudi Arabia.
Mahmoud L; Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, 11211, Riyadh, Saudi Arabia.
Al-Saif M; Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, 11211, Riyadh, Saudi Arabia.
Khabar KSA; Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, 11211, Riyadh, Saudi Arabia.
Hitti EG; Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, 11211, Riyadh, Saudi Arabia. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 09; Vol. 14 (1), pp. 913. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Glucocorticoids*/pharmacology
Glucocorticoids*/therapeutic use
COVID-19*/genetics
Humans ; 3' Untranslated Regions ; A549 Cells ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
The functional role of CST1 and CCL26 in asthma development.
Autorzy:
Hoyer A; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.; Astrid Lindgren Children's Hospital, Karolinska University Hospital, Solna, Sweden.
Chakraborty S; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.; Astrid Lindgren Children's Hospital, Karolinska University Hospital, Solna, Sweden.
Lilienthal I; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.
Konradsen JR; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.; Astrid Lindgren Children's Hospital, Karolinska University Hospital, Solna, Sweden.
Katayama S; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.; Stem Cells and Metabolism Research Program, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.
Söderhäll C; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.; Astrid Lindgren Children's Hospital, Karolinska University Hospital, Solna, Sweden.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Jan; Vol. 12 (1), pp. e1162.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma*/genetics
Chemokine CCL26*/genetics
Salivary Cystatins*/genetics
Animals ; Dogs ; Humans ; A549 Cells ; Interferons
Czasopismo naukowe
Tytuł:
Synthesis and Characterization of Ruthenium-Paraphenylene-Cyclopentadienyl Full-Sandwich Complexes: Cytotoxic Activity against A549 Lung Cancer Cell Line and DNA Binding Properties.
Autorzy:
Sifnaiou E; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Tsolis T; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Ypsilantis K; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Roupakia E; Laboratory of Biology, School of Medicine, Faculty of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.; Institute of Biomedical Research, Foundation for Research and Technology, 45110 Ioannina, Greece.
Kolettas E; Laboratory of Biology, School of Medicine, Faculty of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.; Institute of Biomedical Research, Foundation for Research and Technology, 45110 Ioannina, Greece.
Plakatouras JC; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.; Institute of Materials Science and Computing, University Research Centre of Ioannina (URCI), 45110 Ioannina, Greece.
Garoufis A; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.; Institute of Materials Science and Computing, University Research Centre of Ioannina (URCI), 45110 Ioannina, Greece.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 19; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/drug therapy
Ruthenium*/pharmacology
Antineoplastic Agents*/pharmacology
Biphenyl Compounds*
Humans ; A549 Cells ; Organic Chemicals
Czasopismo naukowe
Tytuł:
Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors.
Autorzy:
El-Kalyoubi S; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Port Said University, Port Said, Egypt.
El-Sebaey SA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Rashad AM; Accelerator and Ion Sources Department, Nuclear Research Center, Atomic Energy Authority, Cairo, Egypt.; Central Lab for Elemental and Isotopic Analysis, NRC, Atomic Energy Authority, Cairo, Egypt.
Al-Ghulikah HA; Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Ghorab MM; Department of Drug Radiation Research, National Centre for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Elfeky SM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2198163.
Typ publikacji:
Journal Article
MeSH Terms:
Pyrimidines*/chemical synthesis
Pyrimidines*/pharmacology
Topoisomerase II Inhibitors*/chemical synthesis
Topoisomerase II Inhibitors*/pharmacology
HSP90 Heat-Shock Proteins*/antagonists & inhibitors
Antineoplastic Agents*/chemical synthesis
Antineoplastic Agents*/pharmacology
Hep G2 Cells ; A549 Cells ; MCF-7 Cells ; Humans ; Cell Proliferation/drug effects ; Gene Expression Regulation/drug effects ; Cell Cycle/drug effects ; Computer Simulation
Czasopismo naukowe
Tytuł:
Glucocorticoids alleviate particulate matter-induced COX-2 expression and mitochondrial dysfunction through the Bcl-2/GR complex in A549 cells.
Autorzy:
Park YJ; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Republic of Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Republic of Korea.
Heo J; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Republic of Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Republic of Korea.
Kim Y; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Republic of Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Republic of Korea.
Cho H; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Republic of Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Republic of Korea.
Shim M; BL Healthcare, Yongin-si, Gyeonggi-do, 16827, South Korea.
Im K; BL Healthcare, Yongin-si, Gyeonggi-do, 16827, South Korea.
Lim W; Department of Sports Medicine, College of Health Science, Cheongju University, Cheongju, 28503, South Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 02; Vol. 13 (1), pp. 18884. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glucocorticoids*/pharmacology
Glucocorticoids*/metabolism
Dexamethasone*/pharmacology
Humans ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; A549 Cells ; Particulate Matter/toxicity ; Dinoprostone/metabolism ; Reactive Oxygen Species ; Inflammation
Czasopismo naukowe
Tytuł:
Notopterol Suppresses IL-17-Induced Proliferation and Invasion of A549 Lung Adenocarcinoma Cells via Modulation of STAT3, NF-κB, and AP-1 Activation.
Autorzy:
Inthanon S; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Dejkriengkraikul P; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; Anticarcinogenesis and Apoptosis Research Cluster, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Yodkeeree S; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; Anticarcinogenesis and Apoptosis Research Cluster, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 11; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/pathology
Lung Neoplasms*/metabolism
Humans ; NF-kappa B/metabolism ; Transcription Factor AP-1/metabolism ; Interleukin-17/pharmacology ; Interleukin-17/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Cell Line, Tumor ; A549 Cells ; Cell Proliferation ; Cell Movement ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe

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