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Wyszukujesz frazę ""accumulation"" wg kryterium: Temat


Tytuł :
Perfect Match Genomic Landscape strategy: Refinement and customization of reference genomes.
Autorzy :
Palacios-Flores K; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
García-Sotelo J; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
Castillo A; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
Uribe C; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
Morales L; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
Boege M; Escuela Nacional de Estudios Superiores Juriquilla, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
Dávila G; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
Flores M; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México.
Palacios R; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, 76230 Querétaro, México; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Apr 06; Vol. 118 (14).
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Variation*
Genome, Microbial*
Genomics/*methods
SARS-CoV-2/*genetics
Algorithms ; Mutation Accumulation ; Proof of Concept Study ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł :
Transforming Candida hispaniensis, a promising oleaginous and flavogenic yeast.
Autorzy :
Morin N; INRAE, AgroParisTech, Université Paris-Saclay, Micalis Institute, Jouy-en-Josas, France.
Czerwiec Q; INRAE, AgroParisTech, Université Paris-Saclay, Micalis Institute, Jouy-en-Josas, France.
Nicaud JM; INRAE, AgroParisTech, Université Paris-Saclay, Micalis Institute, Jouy-en-Josas, France.
Neuvéglise C; INRAE, AgroParisTech, Université Paris-Saclay, Micalis Institute, Jouy-en-Josas, France.
Rossignol T; INRAE, AgroParisTech, Université Paris-Saclay, Micalis Institute, Jouy-en-Josas, France.
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Źródło :
Yeast (Chichester, England) [Yeast] 2020 May; Vol. 37 (5-6), pp. 348-355. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Lipid Accumulation Product*
Candida/*genetics
Candida/*metabolism
Lipids/*biosynthesis
Biotechnology ; Candida/cytology ; Candida/enzymology ; Glucose/metabolism ; Lipid Metabolism ; Riboflavin/biosynthesis ; Transformation, Genetic ; Yarrowia/genetics ; beta-Fructofuranosidase
Czasopismo naukowe
Tytuł :
Will SARS-CoV-2 variants of concern affect the promise of vaccines?
Autorzy :
Gupta RK; Cambridge Institute of Therapeutic Immunology & Infectious Disease, University of Cambridge, Cambridge, UK. .
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Źródło :
Nature reviews. Immunology [Nat Rev Immunol] 2021 Jun; Vol. 21 (6), pp. 340-341.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*prevention & control
COVID-19/*virology
COVID-19 Vaccines/*pharmacology
Pandemics/*prevention & control
SARS-CoV-2/*genetics
SARS-CoV-2/*immunology
COVID-19/immunology ; COVID-19 Vaccines/supply & distribution ; Evolution, Molecular ; Humans ; Mutation Accumulation ; Neutralization Tests ; SARS-CoV-2/pathogenicity ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology ; Virulence/genetics ; Virulence/immunology
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Considering mutational meltdown as a potential SARS-CoV-2 treatment strategy.
Autorzy :
Jensen JD; School of Life Sciences, Arizona State University, Tempe, AZ, USA. .
Lynch M; School of Life Sciences, Arizona State University, Tempe, AZ, USA.
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Źródło :
Heredity [Heredity (Edinb)] 2020 May; Vol. 124 (5), pp. 619-620. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
Mutation Accumulation*
Antiviral Agents/*therapeutic use
Betacoronavirus/*genetics
Coronavirus Infections/*drug therapy
Pneumonia, Viral/*drug therapy
Amides/pharmacology ; Amides/therapeutic use ; Antiviral Agents/pharmacology ; Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections/virology ; Humans ; Models, Genetic ; Pandemics ; Pneumonia, Viral/virology ; Pyrazines/pharmacology ; Pyrazines/therapeutic use ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Mutations Beget More Mutations-Rapid Evolution of Mutation Rate in Response to the Risk of Runaway Accumulation.
Autorzy :
Ruan Y; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Wang H; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Chen B; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Wen H; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Wu CI; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.; Department of Ecology and Evolution, University of Chicago, Chicago, IL.
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Źródło :
Molecular biology and evolution [Mol Biol Evol] 2020 Apr 01; Vol. 37 (4), pp. 1007-1019.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Genetic*
Mutation Accumulation*
Mutation Rate*
Carcinogenesis/genetics ; Evolution, Molecular ; Humans
Czasopismo naukowe
Tytuł :
Predictive performance of lipid accumulation product and visceral adiposity index for renal function decline in non-diabetic adults, an 8.6-year follow-up.
Autorzy :
Mousapour P; Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Barzin M; Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Valizadeh M; Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahdavi M; Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azizi F; Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hosseinpanah F; Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. .
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Źródło :
Clinical and experimental nephrology [Clin Exp Nephrol] 2020 Mar; Vol. 24 (3), pp. 225-234. Date of Electronic Publication: 2019 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Adiposity*
Lipid Accumulation Product*
Renal Insufficiency, Chronic/*physiopathology
Adolescent ; Adult ; Biomarkers ; Female ; Follow-Up Studies ; Humans ; Kidney Function Tests ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Lipid accumulation product and late-onset hypogonadism in middle-aged and elderly men: results from a cross-sectional study in China.
Autorzy :
Sun K; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Wang C; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Lao G; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Lin D; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Huang C; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Li N; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Li L; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Li F; Department of Endocrinology, The Seventh Affiliated Hospital Sun Yat-sen University, Shenzhen, China.
Xiao H; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China .
Yan L; Department of Endocrinology, Sun Yat-sen Memorial Hospital, Guangzhou, China .
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Źródło :
BMJ open [BMJ Open] 2020 Feb 10; Vol. 10 (2), pp. e033991. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypogonadism*/epidemiology
Lipid Accumulation Product*
Aged ; Body Mass Index ; China/epidemiology ; Cross-Sectional Studies ; Humans ; Male ; Middle Aged ; Prevalence ; Testosterone/blood ; Waist Circumference
Czasopismo naukowe
Tytuł :
Implementation of a 1‐D Thermodynamic Model for Simulating the Winter‐Time Evolvement of Physical Properties of Snow and Ice Over the Arctic Ocean.
Autorzy :
Kang, Eui‐Jong (AUTHOR)
Sohn, Byung‐Ju (AUTHOR)
Tonboe, Rasmus Tage (AUTHOR)
Dybkjær, Gorm (AUTHOR)
Holmlund, Kenneth (AUTHOR)
Kim, Jong‐Min (AUTHOR)
Liu, Chao (AUTHOR)
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Źródło :
Journal of Advances in Modeling Earth Systems. Mar2021, Vol. 13 Issue 3, p1-30. 30p.
Czasopismo naukowe
Tytuł :
Trends and spatial variation in rain-on-snow events over the Arctic Ocean during the early melt season.
Autorzy :
Dou, Tingfeng (AUTHOR)
Xiao, Cunde (AUTHOR)
Liu, Jiping (AUTHOR)
Wang, Qiang (AUTHOR)
Pan, Shifeng (AUTHOR)
Su, Jie (AUTHOR)
Yuan, Xiaojun (AUTHOR)
Ding, Minghu (AUTHOR)
Zhang, Feng (AUTHOR)
Xue, Kai (AUTHOR)
Bieniek, Peter A. (AUTHOR)
Eicken, Hajo (AUTHOR)
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Źródło :
Cryosphere. Feb2021, Vol. 15 Issue 2, p883-895. 13p.
Czasopismo naukowe
Tytuł :
Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival.
Autorzy :
Wood MA; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Portland VA Research Foundation, Portland, USA.
Weeder BR; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.
David JK; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.
Nellore A; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.; Department of Surgery, Oregon Health & Science University, Portland, USA.
Thompson RF; Computational Biology Program, Oregon Health & Science University, Portland, USA. .; Portland VA Research Foundation, Portland, USA. .; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA. .; Department of Radiation Medicine, Oregon Health & Science University, Portland, USA. .; Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, USA. .; VA Portland Healthcare System, Division of Hospital and Specialty Medicine, Portland, USA. .
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Źródło :
Genome medicine [Genome Med] 2020 Mar 30; Vol. 12 (1), pp. 33. Date of Electronic Publication: 2020 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Mutation Accumulation*
Carcinoma, Non-Small-Cell Lung/*genetics
Immune Checkpoint Inhibitors/*therapeutic use
Lung Neoplasms/*genetics
Melanoma/*genetics
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Epitopes/genetics ; Epitopes/immunology ; Humans ; Lung Neoplasms/drug therapy ; Melanoma/drug therapy
Czasopismo naukowe
Tytuł :
Mutation accumulation in cancer genes relates to nonoptimal outcome in chronic myeloid leukemia.
Autorzy :
Adnan Awad S; Hematology Research Unit Helsinki, Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Clinical and Chemical Pathology Department, National Cancer Institute, Cairo University, Giza, Egypt.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Kankainen M; Hematology Research Unit Helsinki, Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine and.; Department of Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; and.
Ojala T; Department of Pharmacology, Faculty of Medicine, and.
Koskenvesa P; Hematology Research Unit Helsinki, Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
Eldfors S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Ghimire B; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Kumar A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Kytölä S; Department of Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; and.
Kamel MM; Clinical and Chemical Pathology Department, National Cancer Institute, Cairo University, Giza, Egypt.
Heckman CA; iCAN Digital Precision Cancer Medicine and.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Porkka K; Hematology Research Unit Helsinki, Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine and.
Mustjoki S; Hematology Research Unit Helsinki, Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine and.
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Źródło :
Blood advances [Blood Adv] 2020 Feb 11; Vol. 4 (3), pp. 546-559.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics
Mutation Accumulation*
Blast Crisis ; Fusion Proteins, bcr-abl/genetics ; Genes, Neoplasm ; Humans
Czasopismo naukowe
Tytuł :
A compartment size-dependent selective threshold limits mutation accumulation in hierarchical tissues.
Autorzy :
Grajzel D; MTA-ELTE 'Lendület' Evolutionary Genomics Research Group, H-1117 Budapest, Hungary.; Department of Biological Physics, Eötvös Loránd University, H-1117 Budapest, Hungary.
Derényi I; Department of Biological Physics, Eötvös Loránd University, H-1117 Budapest, Hungary.; MTA-ELTE Statistical and Biological Physics Research Group, Hungarian Academy of Sciences, H-1117 Budapest, Hungary.
Szöllősi GJ; MTA-ELTE 'Lendület' Evolutionary Genomics Research Group, H-1117 Budapest, Hungary; .; Department of Biological Physics, Eötvös Loránd University, H-1117 Budapest, Hungary.; Evolutionary Systems Research Group, Centre for Ecological Research, Hungarian Academy of Sciences, 8237 Tihany, Hungary.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 21; Vol. 117 (3), pp. 1606-1611. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Genetic*
Mutation Accumulation*
Genes, Neoplasm/*genetics
Neoplasms/*genetics
Cell Differentiation/genetics ; Cell Division ; Clonal Evolution/genetics ; Computer Simulation ; Cytoprotection/genetics ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
Beyond tumor mutational burden: potential and limitations in using exosomes to predict response to immunotherapy.
Autorzy :
Crow J; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Samuel G; Division of Hematology Oncology, and Bone Marrow Transplant, The Children's Mercy Hospital, Kansas City, MO, USA.
Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.; University of Kansas Cancer Center, University of Kansas Medical Center, Kansas City, KS, USA.
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Źródło :
Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2019 Dec; Vol. 19 (12), pp. 1079-1088. Date of Electronic Publication: 2019 Nov 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immunotherapy*
Mutation Accumulation*
Biomarkers, Tumor/*genetics
Exosomes/*genetics
Neoplasms/*genetics
Biomarkers, Tumor/metabolism ; Exosomes/metabolism ; Genomics/methods ; Humans ; Neoplasms/therapy
Czasopismo naukowe
Tytuł :
Interaction of lipid accumulation product and family history of hypertension on hypertension risk: a cross-sectional study in the Southern Chinese population.
Autorzy :
Huang J; School of Public Health, Guangzhou Medical University, Guangzhou, China.; General Practice Center, Nanhai Hospital, Southern Medical University, Foshan, China.
Bao X; School of Public Health, Guangzhou Medical University, Guangzhou, China.
Xie Y; School of Public Health, Guangzhou Medical University, Guangzhou, China.
Zhang X; School of Public Health, Guangzhou Medical University, Guangzhou, China.
Peng X; School of Public Health, Guangzhou Medical University, Guangzhou, China.
Liu Y; School of Public Health, Guangzhou Medical University, Guangzhou, China.
Cheng M; School of Public Health, Guangzhou Medical University, Guangzhou, China.
Ma J; School of Public Health, Guangzhou Medical University, Guangzhou, China .
Wang P; General Practice Center, Nanhai Hospital, Southern Medical University, Foshan, China .
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Źródło :
BMJ open [BMJ Open] 2019 Nov 28; Vol. 9 (11), pp. e029253. Date of Electronic Publication: 2019 Nov 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipid Accumulation Product*
Hypertension/*epidemiology
Obesity/*epidemiology
Triglycerides/*blood
Adult ; Anthropometry ; Body Mass Index ; China ; Comorbidity ; Cross-Sectional Studies ; Female ; Humans ; Hypertension/blood ; Male ; Middle Aged ; Obesity/blood ; Risk Assessment ; Risk Factors ; Waist Circumference ; Waist-Hip Ratio
Czasopismo naukowe

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