Temat: "accumulation" - OpacWWW

Skocz do pozycji: 21.

Tytuł:: Lipid Accumulation Product Index to Predict Metabolic Syndrome in People Living with HIV.
Autorzy:: Raposo MA; Department of Infectology and Tropical Medicine, Faculty of Medicine - Federal University of Minas Gerais (UFMG) - Belo Horizonte, Minas Gerais - Brazil .
Guimarães NS; Department of Infectology and Tropical Medicine, Faculty of Medicine - Federal University of Minas Gerais (UFMG) - Belo Horizonte, Minas Gerais - Brazil.
Tupinambás U; Department of Infectology and Tropical Medicine, Faculty of Medicine - Federal University of Minas Gerais (UFMG) - Belo Horizonte, Minas Gerais - Brazil.; Pokaż więcej
Źródło:: Clinical medicine & research [Clin Med Res] 2020 Dec; Vol. 18 (4), pp. 120-125. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji:: Journal Article
MeSH Terms:: HIV Infections*/complications
HIV Infections*/epidemiology
Lipid Accumulation Product*
Metabolic Syndrome*/complications
Metabolic Syndrome*/diagnosis
Metabolic Syndrome*/epidemiology
Adult ; Cross-Sectional Studies ; Female ; Humans ; Male ; Waist Circumference

Czasopismo naukowe

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Skocz do pozycji: 22.

Tytuł:: Hypertriglyceridemic Waist Phenotype and Lipid Accumulation Product: Two Comprehensive Obese Indicators of Waist Circumference and Triglyceride to Predict Type 2 Diabetes Mellitus in Chinese Population.
Autorzy:: Xu M; Wujin District Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Huang M; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.; Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.; Department of Prenatal Diagnosis, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, Nanjing, China.
Qiang D; Wujin District Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Gu J; Wujin District Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Li Y; Wujin District Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Pan Y; Wujin District Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Yao X; Changzhou Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Xu W; Changzhou Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Tao Y; Department of Medical Affairs, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Zhou Y; Wujin District Center for Disease Prevention and Control, Changzhou, Jiangsu, China.
Ma H; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.; Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.; Pokaż więcej
Źródło:: Journal of diabetes research [J Diabetes Res] 2020 Dec 02; Vol. 2020, pp. 9157430. Date of Electronic Publication: 2020 Dec 02 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Lipid Accumulation Product*
Waist Circumference*
Diabetes Mellitus, Type 2/*epidemiology
Hypertriglyceridemia/*diagnosis
Obesity/*diagnosis
Triglycerides/*blood
Adult ; Biomarkers/blood ; Blood Glucose/metabolism ; China/epidemiology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Female ; Humans ; Hypertriglyceridemia/blood ; Hypertriglyceridemia/epidemiology ; Incidence ; Male ; Middle Aged ; Obesity/blood ; Obesity/epidemiology ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Risk Assessment ; Risk Factors ; Rural Health

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Skocz do pozycji: 23.

Tytuł:: Demographic history shaped geographical patterns of deleterious mutation load in a broadly distributed Pacific Salmon.
Autorzy:: Rougemont Q; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
Moore JS; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
Leroy T; ISEM, Univ. Montpellier, CNRS, EPHE, IRD, Montpellier, France.; Department of Botany & Biodiversity Research, University of Vienna, Vienna, Austria.
Normandeau E; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
Rondeau EB; Centre for Biomedical Research, University of Victoria, Victoria, BC, Canada.; Department of Biology, University of Victoria, Victoria, BC, Canada.
Withler RE; Department of Fisheries and Ocean, Pacific Biological Station, Nanaimo, British Columbia, Canada.
Van Doornik DM; National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Northwest Fisheries Science Center, Manchester Research Station, Port Orchard, Washington, United States of America.
Crane PA; Conservation Genetics Laboratory, U.S. Fish and Wildlife Service, Anchorage, Alaska, United States of America.
Naish KA; School of Aquatic and Fishery Sciences, University of Washington, Seattle, WA, United States of America.
Garza JC; Fisheries Ecology Division, Southwest Fisheries Science Center, National Marine Fisheries Service and Institute of Marine Sciences, University of California-Santa Cruz, Santa Cruz, California, United States of America.
Beacham TD; Department of Fisheries and Ocean, Pacific Biological Station, Nanaimo, British Columbia, Canada.
Koop BF; Centre for Biomedical Research, University of Victoria, Victoria, BC, Canada.; Department of Biology, University of Victoria, Victoria, BC, Canada.
Bernatchez L; Département de Biologie, Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2020 Aug 26; Vol. 16 (8), pp. e1008348. Date of Electronic Publication: 2020 Aug 26 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Animal Distribution*
Mutation Accumulation*
Oncorhynchus kisutch/*genetics
Animals ; Evolution, Molecular ; Models, Genetic

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Skocz do pozycji: 24.

Tytuł:: mtDNA Mutation Accumulation in Muscle Is Not a Major Cause of Fiber Loss. Reply to "Comment on: Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging. Cells 2020, 9 , 197".
Autorzy:: Hepple RT; Department of Physical Therapy, University of Florida, Gainesville, FL 32610, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Aug 01; Vol. 9 (8). Date of Electronic Publication: 2020 Aug 01.
Typ publikacji:: Letter; Comment
MeSH Terms:: DNA, Mitochondrial*/genetics
Mutation Accumulation*
Mitochondria/genetics ; Neuromuscular Junction/metabolism

Opinia redakcyjna

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Skocz do pozycji: 25.

Tytuł:: Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis.
Autorzy:: Hasaart KAL; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
Manders F; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
van der Hoorn ML; Leiden University Medical Center, 2333 ZC, Leiden, The Netherlands.
Verheul M; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
Poplonski T; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands.
Kuijk E; Center for Molecular Medicine, University Medical Center Utrecht and Oncode Institute, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
de Sousa Lopes SMC; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC, Leiden, The Netherlands.
van Boxtel R; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Jul 31; Vol. 10 (1), pp. 12991. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Down Syndrome*/embryology
Down Syndrome*/genetics
Down Syndrome*/pathology
Mutation Accumulation*
Cell Lineage/*genetics
Fetus/*metabolism
Hematopoiesis/*genetics
Hematopoietic Stem Cells/*metabolism
Female ; Fetus/pathology ; Hematopoietic Stem Cells/pathology ; Humans ; Leukemia/embryology ; Leukemia/genetics ; Leukemia/pathology ; Male ; Whole Genome Sequencing

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Skocz do pozycji: 26.

Tytuł:: A little bit of sex prevents mutation accumulation even in apomictic polyploid plants.
Autorzy:: Hodač L; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany.
Klatt S; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany.
Hojsgaard D; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany.
Sharbel TF; Global Institute for Food Security, University of Saskatchewan, Saskatoon, Canada.
Hörandl E; Department of Systematics, Biodiversity and Evolution of Plants (with Herbarium), University of Goettingen, Goettingen, Germany. .; Pokaż więcej
Źródło:: BMC evolutionary biology [BMC Evol Biol] 2019 Aug 14; Vol. 19 (1), pp. 170. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mutation Accumulation*
Recombination, Genetic*
Ranunculus/*genetics
DNA, Plant/analysis ; DNA, Plant/genetics ; Microsatellite Repeats ; Mutation Rate ; Ovule ; Polyploidy ; Ranunculus/growth & development ; Ranunculus/physiology ; Reproduction, Asexual

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Skocz do pozycji: 27.

Tytuł:: Molecular footprint of Medawar's mutation accumulation process in mammalian aging.
Autorzy:: Turan ZG; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Parvizi P; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Dönertaş HM; European Molecular Biology Laboratory, European Bioinformatics Institute EMBL-EBI, Wellcome Trust Genome Campus, Cambridge, UK.
Tung J; Department of Evolutionary Anthropology, Duke University, Durham, North Carolina.; Department of Biology, Duke University, Durham, North Carolina.; Duke Population Research Institute, Duke University, Durham, North Carolina.
Khaitovich P; Center for Neurobiology and Brain Restoration, Skolkovo Institute of Science and Technology, Moscow, Russia.; CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Somel M; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2019 Aug; Vol. 18 (4), pp. e12965. Date of Electronic Publication: 2019 May 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Evolution, Molecular*
Mutation Accumulation*
Selection, Genetic*
Transcriptome*
Aging/*genetics
Alleles ; Animals ; Databases, Genetic ; Genetic Drift ; Humans ; Macaca/genetics ; Mice ; Phenotype ; Rats ; Up-Regulation/genetics

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Skocz do pozycji: 28.

Tytuł:: Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival.
Autorzy:: Wood MA; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Portland VA Research Foundation, Portland, USA.
Weeder BR; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.
David JK; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.
Nellore A; Computational Biology Program, Oregon Health & Science University, Portland, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA.; Department of Surgery, Oregon Health & Science University, Portland, USA.
Thompson RF; Computational Biology Program, Oregon Health & Science University, Portland, USA. .; Portland VA Research Foundation, Portland, USA. .; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA. .; Department of Radiation Medicine, Oregon Health & Science University, Portland, USA. .; Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, USA. .; VA Portland Healthcare System, Division of Hospital and Specialty Medicine, Portland, USA. .; Pokaż więcej
Źródło:: Genome medicine [Genome Med] 2020 Mar 30; Vol. 12 (1), pp. 33. Date of Electronic Publication: 2020 Mar 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Mutation Accumulation*
Carcinoma, Non-Small-Cell Lung/*genetics
Immune Checkpoint Inhibitors/*therapeutic use
Lung Neoplasms/*genetics
Melanoma/*genetics
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Epitopes/genetics ; Epitopes/immunology ; Humans ; Lung Neoplasms/drug therapy ; Melanoma/drug therapy

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Skocz do pozycji: 29.

Tytuł:: Visceral adiposity index (VAI), lipid accumulation product (LAP), and product of triglycerides and glucose (TyG) to discriminate prediabetes and diabetes.
Autorzy:: Ahn N; Chair of Epidemiology, Ludwig-Maximilians-Universität München, UNIKA-T Augsburg, Augsburg, Germany. .; The Institute of Medical Informatics, Biometry and Epidemiology (IBE), Ludwig-Maximilians-University of Munich, Munich, Germany. .
Baumeister SE; Chair of Epidemiology, Ludwig-Maximilians-Universität München, UNIKA-T Augsburg, Augsburg, Germany.
Amann U; Chair of Epidemiology, Ludwig-Maximilians-Universität München, UNIKA-T Augsburg, Augsburg, Germany.
Rathmann W; Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.
Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Huth C; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Thorand B; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Meisinger C; Chair of Epidemiology, Ludwig-Maximilians-Universität München, UNIKA-T Augsburg, Augsburg, Germany.; Independent Research Group Clinical Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Jul 04; Vol. 9 (1), pp. 9693. Date of Electronic Publication: 2019 Jul 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adiposity*
Lipid Accumulation Product*
Diabetes Mellitus, Type 2/*diagnosis
Glucose/*metabolism
Intra-Abdominal Fat/*physiopathology
Obesity, Abdominal/*physiopathology
Prediabetic State/*diagnosis
Triglycerides/*metabolism
Adult ; Aged ; Biomarkers/analysis ; Diabetes Mellitus, Type 2/epidemiology ; Diagnosis, Differential ; Female ; Germany/epidemiology ; Humans ; Male ; Middle Aged ; Prediabetic State/epidemiology ; ROC Curve ; Risk Factors

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Skocz do pozycji: 30.

Tytuł:: Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii.
Autorzy:: Böndel KB; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
Kraemer SA; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.; Biology Department, Concordia University, Montreal, Quebec, Canada.
Samuels T; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
McClean D; Institute of Immunology and Infection Research, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
Lachapelle J; Department of Biology, William G. Davis Building, University of Toronto, Mississauga, Canada.
Ness RW; Department of Biology, William G. Davis Building, University of Toronto, Mississauga, Canada.
Colegrave N; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.
Keightley PD; Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2019 Jun 26; Vol. 17 (6), pp. e3000192. Date of Electronic Publication: 2019 Jun 26 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mutation Accumulation*
Chlamydomonas reinhardtii/*genetics
DNA Mutational Analysis/*methods
Genetic Fitness/*genetics
Bayes Theorem ; Biological Evolution ; Evolution, Molecular ; Genetic Variation ; Genotype ; Models, Genetic ; Mutagenesis ; Mutation/genetics ; Mutation Rate ; Selection, Genetic/genetics

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Skocz do pozycji: 31.

Tytuł:: Muver, a computational framework for accurately calling accumulated mutations.
Autorzy:: Burkholder AB; Integrative Bioinformatics, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, Durham, NC, 27709, USA.
Lujan SA; Laboratory of Genomic Integrity and Structural Biology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, Durham, NC, 27709, USA.
Lavender CA; Integrative Bioinformatics, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, Durham, NC, 27709, USA.
Grimm SA; Integrative Bioinformatics, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, Durham, NC, 27709, USA.
Kunkel TA; Laboratory of Genomic Integrity and Structural Biology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, Durham, NC, 27709, USA.
Fargo DC; Integrative Bioinformatics, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, Durham, NC, 27709, USA. .; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2018 May 09; Vol. 19 (1), pp. 345. Date of Electronic Publication: 2018 May 09.
Typ publikacji:: Journal Article
MeSH Terms:: Genome, Fungal*
Mutation Accumulation*
Software*
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Sequence Analysis, DNA/*methods
Computational Biology ; Fathers ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Mutation Rate ; Reference Standards

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Skocz do pozycji: 32.

Tytuł:: Characterization of a Treponema denticola ATCC 35405 mutant strain with mutation accumulation, including a lack of phage-derived genes.
Autorzy:: Yokogawa T; Division of Orthodontics and Dentofacial Orthopedics, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan.
Nagano K; Division of Microbiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan.
Fujita M; Division of Microbiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan.
Miyakawa H; Division of Microbiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan.
Iijima M; Division of Orthodontics and Dentofacial Orthopedics, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jun 24; Vol. 17 (6), pp. e0270198. Date of Electronic Publication: 2022 Jun 24 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacteriophages*/genetics
Treponema denticola*/genetics
Bacterial Proteins/genetics ; Bacterial Typing Techniques ; Mutation Accumulation ; Treponema/genetics

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Skocz do pozycji: 33.

Tytuł:: Tumor Mutation Load: A Novel Independent Prognostic Factor in Stage IIIA-N2 Non-Small-Cell Lung Cancer.
Autorzy:: Kang J; Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Luo Y; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Wang D; Department of Clinical Laboratory, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Men Y; Department of VIP Medical Services & Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Wang J; Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Che YQ; Department of Clinical Laboratory, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Hui Z; Department of VIP Medical Services & Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.; Pokaż więcej
Źródło:: Disease markers [Dis Markers] 2019 Apr 30; Vol. 2019, pp. 3837687. Date of Electronic Publication: 2019 Apr 30 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Mutation Accumulation*
Mutation Rate*
Biomarkers, Tumor/*genetics
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Carcinoma, Non-Small-Cell Lung/pathology ; Female ; Genes, Tumor Suppressor ; Humans ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis

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Skocz do pozycji: 34.

Tytuł:: No signal of deleterious mutation accumulation in conserved gene sequences of extant asexual hexapods.
Autorzy:: Brandt A; University of Göttingen, JF Blumenbach Institute of Zoology and Anthropology, Untere Karspüle 2, D-37073, Göttingen, Germany. .
Bast J; University of Lausanne, Department of Ecology and Evolution, UNIL Sorge, Le Biophore, CH-1015, Lausanne, Switzerland.
Scheu S; University of Göttingen, JF Blumenbach Institute of Zoology and Anthropology, Untere Karspüle 2, D-37073, Göttingen, Germany.
Meusemann K; University of Freiburg, Biology I, Evolutionary Biology & Ecology, Hauptstraße 1, D-79104, Freiburg, Germany.; Center for Molecular Biodiversity Research (ZMB), Zoological Research Museum Alexander König, Adenauerallee 160, D-53113, Bonn, Germany.
Donath A; Center for Molecular Biodiversity Research (ZMB), Zoological Research Museum Alexander König, Adenauerallee 160, D-53113, Bonn, Germany.
Schütte K; University of Hamburg, Faculty of Mathematics, Informatics and Natural Sciences, Department of Biology, Institute of Zoology, Research Unit Animal Ecology and Conservation, Martin-Luther-King-Platz 3, D-20146, Hamburg, Germany.
Machida R; Sugadaira Research Station, Mountain Science Center, University of Tsukuba, 1278-294, Sugadaira Kogen, Ueda, Nagano, 386-2204, Japan.
Kraaijeveld K; University of Amsterdam, Institute for Biodiversity and Ecosystem Dynamics, Science Park 904, 1090 GE, Amsterdam, The Netherlands.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Mar 29; Vol. 9 (1), pp. 5338. Date of Electronic Publication: 2019 Mar 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Conserved Sequence*
Mutation Accumulation*
Insecta/*genetics
Reproduction, Asexual/*genetics
Animals ; Evolution, Molecular ; Insecta/classification ; Selection, Genetic ; Silent Mutation ; Species Specificity

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Skocz do pozycji: 35.

Tytuł:: Mutation rate and spectrum in obligately outcrossing Caenorhabditis elegans mutation accumulation lines subjected to RNAi-induced knockdown of the mismatch repair gene msh-2.
Autorzy:: Katju V; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77845, USA.
Konrad A; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77845, USA.; Faculdade de Ciência da Universidade de Lisboa (FCUL), CE3C-Centre for Ecology, Evolution and Environmental Changes, 1749-016 Lisboa, Portugal.
Deiss TC; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77845, USA.
Bergthorsson U; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77845, USA.; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2022 Jan 04; Vol. 12 (1).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Caenorhabditis elegans*/genetics
Mutation Rate*
Animals ; DNA Mismatch Repair/genetics ; Female ; Male ; Mutation ; Mutation Accumulation ; RNA Interference

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Skocz do pozycji: 36.

Tytuł:: Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study.
Autorzy:: Kawakami S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Takano S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan. .
Fukasawa M; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Shindo H; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Takahashi E; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Fukasawa Y; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Hayakawa H; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kuratomi N; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kadokura M; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Hosomura N; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Amemiya H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Kawaida H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Kono H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Maekawa S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Ichikawa D; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Enomoto N; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2021 Nov 19; Vol. 21 (1), pp. 1245. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:: Journal Article
MeSH Terms:: Mutation*
Gallbladder Neoplasms/*genetics
Genes, p53/*genetics
Pancreaticobiliary Maljunction/*genetics
Adult ; Aged ; Case-Control Studies ; Cholecystitis/genetics ; Female ; Gene Expression Profiling ; Genes, Retinoblastoma ; Genes, erbB-1 ; Genes, erbB-2 ; Genes, ras ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Mutation Accumulation ; Retrospective Studies ; Risk Factors

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Skocz do pozycji: 37.

Tytuł:: Whole Genome Sequence Analysis of Mutations Accumulated in rad27 Δ Yeast Strains with Defects in the Processing of Okazaki Fragments Indicates Template-Switching Events.
Autorzy:: Omer S; Department of Natural and Life Sciences, The Open University of Israel, 4353701 Ra'anana, Israel.; Department of Plant Pathology and Microbiology, Robert H. Smith Faculty of Agriculture, Food and Environment, Hebrew University, 76100 Rehovot, Israel.
Lavi B; Department of Natural and Life Sciences, The Open University of Israel, 4353701 Ra'anana, Israel.; Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, 69978, Israel.
Mieczkowski PA; Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina 27599.
Covo S; Department of Plant Pathology and Microbiology, Robert H. Smith Faculty of Agriculture, Food and Environment, Hebrew University, 76100 Rehovot, Israel .
Hazkani-Covo E; Department of Natural and Life Sciences, The Open University of Israel, 4353701 Ra'anana, Israel .; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2017 Nov 06; Vol. 7 (11), pp. 3775-3787. Date of Electronic Publication: 2017 Nov 06.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Replication*
Mutation Accumulation*
DNA/*genetics
Flap Endonucleases/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Genome, Fungal ; INDEL Mutation ; Microsatellite Repeats

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Skocz do pozycji: 38.

Tytuł:: What Are the Biomarkers for Immunotherapy in SCLC?
Autorzy:: Longo V; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Catino A; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Montrone M; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Pizzutilo P; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Annese T; Department of Basic Medical Sciences, Neurosciences, and Sensory Organs, University of Bari Medical School, 70124 Bari, Italy.
Pesola F; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Marech I; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Cassiano S; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Ribatti D; Department of Basic Medical Sciences, Neurosciences, and Sensory Organs, University of Bari Medical School, 70124 Bari, Italy.
Galetta D; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 15; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Immunotherapy*/methods
Biomarkers, Tumor/*analysis
Lung Neoplasms/*therapy
Small Cell Lung Carcinoma/*therapy
Animals ; Biomarkers, Pharmacological/analysis ; Biomarkers, Tumor/isolation & purification ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Mutation Accumulation ; Prognosis ; Small Cell Lung Carcinoma/diagnosis ; Small Cell Lung Carcinoma/genetics ; Small Cell Lung Carcinoma/metabolism ; Treatment Outcome

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Skocz do pozycji: 39.

Tytuł:: Comparison of various insulin resistance surrogates on prognostic prediction and stratification following percutaneous coronary intervention in patients with and without type 2 diabetes mellitus.
Autorzy:: Zhao Q; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, 100029, China.
Cheng YJ; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, 100029, China.
Xu YK; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, 100029, China.
Zhao ZW; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, 100029, China.
Liu C; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, 100029, China.
Sun TN; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, 100029, China.
Zhou YJ; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, 100029, China. .; Pokaż więcej
Źródło:: Cardiovascular diabetology [Cardiovasc Diabetol] 2021 Sep 18; Vol. 20 (1), pp. 190. Date of Electronic Publication: 2021 Sep 18.
Typ publikacji:: Comparative Study; Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin Resistance*
Percutaneous Coronary Intervention*/adverse effects
Percutaneous Coronary Intervention*/mortality
Acute Coronary Syndrome/*therapy
Diabetes Mellitus, Type 2/*diagnosis
Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/mortality ; Adiposity ; Aged ; Biomarkers/blood ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/mortality ; Diabetes Mellitus, Type 2/physiopathology ; Female ; Humans ; Lipid Accumulation Product ; Lipids/blood ; Male ; Middle Aged ; Predictive Value of Tests ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome

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Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 40.

Tytuł:: Mechanisms of glycosylase induced genomic instability.
Autorzy:: Eyler DE; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, United States of America.
Burnham KA; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, United States of America.
Wilson TE; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, United States of America.; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, United States of America.
O'Brien PJ; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Mar 23; Vol. 12 (3), pp. e0174041. Date of Electronic Publication: 2017 Mar 23 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Mutation Accumulation*
DNA Glycosylases/*metabolism
DNA Copy Number Variations/genetics ; DNA Repair/genetics ; Frameshift Mutation/genetics ; Humans ; Microsatellite Repeats/genetics ; Mutagenesis/genetics ; Point Mutation/genetics ; Saccharomyces cerevisiae/genetics

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