Temat: "acetylcholine" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: RC-4BC cells express nicotinic and muscarinic acetylcholine receptors.
Autorzy:: Zhubanova G; Biology Department, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan, Republic of Kazakhstan.
Filchakova O; Biology Department, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan, Republic of Kazakhstan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Dec 16; Vol. 17 (12), pp. e0279284. Date of Electronic Publication: 2022 Dec 16 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Nicotine*/metabolism
Receptors, Nicotinic*/genetics
Receptors, Nicotinic*/metabolism
Animals ; Rats ; Receptors, Muscarinic/genetics ; Receptors, Muscarinic/metabolism ; Acetylcholine/metabolism ; Pituitary Gland/metabolism

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Skocz do pozycji: 2.

Tytuł:: From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19?
Autorzy:: Gauthier AG; Department of Pharmaceutical Sciences, St. John's University, Queens, NY, USA.
Lin M; Department of Pharmaceutical Sciences, St. John's University, Queens, NY, USA.
Wu J; Department of Pharmaceutical Sciences, St. John's University, Queens, NY, USA.
Kennedy TP; School of Medicine, Tulane University, New Orleans, LA, USA.
Daley LA; Department of Pharmaceutical Sciences, St. John's University, Queens, NY, USA.
Ashby CR Jr; Department of Pharmaceutical Sciences, St. John's University, Queens, NY, USA.
Mantell LL; Department of Pharmaceutical Sciences, St. John's University, Queens, NY, USA.; The Feinstein Institute for Medical Research, Northwell Health System, Manhasset, NY, USA.; Pokaż więcej
Źródło:: Journal of immunotoxicology [J Immunotoxicol] 2021 Dec; Vol. 18 (1), pp. 23-29.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural
MeSH Terms:: COVID-19 Drug Treatment*
Benzylidene Compounds/*pharmacology
Cholinergic Agents/*pharmacology
Inflammation/*drug therapy
Nicotine/*metabolism
Pyridines/*pharmacology
SARS-CoV-2/*physiology
Tobacco Use Disorder/*drug therapy
Antibodies, Monoclonal, Humanized/therapeutic use ; Cigarette Smoking/adverse effects ; Dexamethasone/therapeutic use ; HMGB1 Protein/blood ; Humans ; Pandemics ; alpha7 Nicotinic Acetylcholine Receptor/agonists

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Skocz do pozycji: 3.

Tytuł:: Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters.
Autorzy:: González-Gutiérrez JP; Departamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380492 Santiago, Chile. .
Pessoa-Mahana HA; Departamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380492 Santiago, Chile. .
Iturriaga-Vásquez PE; Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería y Ciencias, Universidad de la Frontera, 4811230 Temuco, Chile. .; Center of Excellence in Biotechnology Research Applied to the Environment, Universidad de La Frontera, 4811230 Temuco, Chile. .
Reyes-Parada MI; Centro de Investigación Biomédica y Aplicada (CIBAP), Escuela de Medicina, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, 9170022 Santiago, Chile. .; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, 3467987 Sede Talca, Chile. .
Guerra-Díaz NE; Departamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380492 Santiago, Chile. .
Hodar-Salazar M; Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería y Ciencias, Universidad de la Frontera, 4811230 Temuco, Chile. .
Viscarra F; Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería y Ciencias, Universidad de la Frontera, 4811230 Temuco, Chile. .
Paillali P; Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería y Ciencias, Universidad de la Frontera, 4811230 Temuco, Chile. .
Núñez-Vivanco G; Centro de Bioinformática y Simulación Molecular, Universidad de Talca, 3340000 Talca, Chile. .; Escuela de Ingeniería Civil en Bioinformática, Universidad de Talca, Av. Lircay 3340000 Talca, Chile. .
Lorca-Carvajal MA; Instituto de Química y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, 2360102 Valparaíso, Chile. .
Mella-Raipán J; Instituto de Química y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, 2360102 Valparaíso, Chile. .
Zúñiga MC; Departamento de Química Inorgánica and Analítica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380492 Santiago, Chile. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2019 Oct 22; Vol. 24 (20). Date of Electronic Publication: 2019 Oct 22.
Typ publikacji:: Journal Article
MeSH Terms:: Acetylcholine/*analogs & derivatives
Dopamine Plasma Membrane Transport Proteins/*chemistry
Nicotine/*analogs & derivatives
Receptors, Nicotinic/*chemistry
Serotonin Plasma Membrane Transport Proteins/*chemistry
Acetylcholine/agonists ; Acetylcholine/chemical synthesis ; Acetylcholine/chemistry ; Allosteric Regulation ; Binding Sites ; Dopamine/chemistry ; Dopamine Agonists/chemistry ; Dopamine Plasma Membrane Transport Proteins/agonists ; Esters/chemistry ; HEK293 Cells ; Humans ; Ligands ; Molecular Docking Simulation ; Nicotine/agonists ; Nicotine/chemical synthesis ; Nicotine/chemistry ; Nicotinic Agonists/chemistry ; Pyrrolidines/chemistry ; Radioligand Assay ; Serotonin Plasma Membrane Transport Proteins/agonists ; Structure-Activity Relationship

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Skocz do pozycji: 4.

Tytuł:: YAP-Dependent BiP Induction Is Involved in Nicotine-Mediated Oral Cancer Malignancy.
Autorzy:: Chien CY; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Chen YC; Molecular and Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Science, National Defense Medical Center, Taipei 114, Taiwan.
Hsu CC; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Chou YT; Institute of Biotechnology, National Tsing Hua University, Hsinchu 300, Taiwan.
Shiah SG; National Institute of Cancer Research, National Health Research Institutes, Miaoli 350, Taiwan.
Liu SY; Department of Oral and Maxillofacial Surgery, Chi Mei Medical Center, Tainan 710, Taiwan.
Hsieh AC; School of Traditional Chinese Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Yen CY; Department of Oral and Maxillofacial Surgery, Chi Mei Medical Center, Tainan 710, Taiwan.; School of Dentistry, Taipei Medical University, Taipei 110, Taiwan.
Lee CH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.; Department and Graduate Institute of Biochemistry, National Defense Medical Center, Taipei 114, Taiwan.
Shieh YS; Department and Graduate Institute of Biochemistry, National Defense Medical Center, Taipei 114, Taiwan.; Department of Dentistry, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Aug 13; Vol. 10 (8). Date of Electronic Publication: 2021 Aug 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Squamous Cell/*pathology
Cell Cycle Proteins/*metabolism
Heat-Shock Proteins/*metabolism
Mouth Neoplasms/*pathology
Nicotine/*pharmacology
Transcription Factors/*metabolism
Animals ; Carcinoma, Squamous Cell/drug therapy ; Cell Cycle Proteins/antagonists & inhibitors ; Cell Cycle Proteins/genetics ; Cell Line, Tumor ; Cell Movement/drug effects ; Endoplasmic Reticulum Chaperone BiP ; Epithelial-Mesenchymal Transition/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Heat-Shock Proteins/antagonists & inhibitors ; Heat-Shock Proteins/genetics ; Humans ; Male ; Mice, Nude ; Mouth Neoplasms/drug therapy ; RNA Interference ; RNA, Small Interfering/metabolism ; RNA, Small Interfering/therapeutic use ; Signal Transduction/drug effects ; Smoking/adverse effects ; Transcription Factors/antagonists & inhibitors ; Transcription Factors/genetics ; alpha7 Nicotinic Acetylcholine Receptor/metabolism ; Mice

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Skocz do pozycji: 5.

Tytuł:: Nicotine self-administration with menthol and audiovisual cue facilitates differential packaging of CYP2A6 and cytokines/chemokines in rat plasma extracellular vesicles.
Autorzy:: Kumar A; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Sinha N; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Haque S; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Kodidela S; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Wang T; Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Martinez AG; Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Chen H; Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Kumar S; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Aug 30; Vol. 11 (1), pp. 17393. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Chemokines/*blood
Cytochrome P-450 CYP2A6/*metabolism
Cytokines/*blood
Extracellular Vesicles/*metabolism
Menthol/*administration & dosage
Nicotine/*administration & dosage
Animals ; Antioxidants/metabolism ; Female ; Male ; Nicotine/metabolism ; Rats ; Self Administration ; Tetraspanin 29/metabolism ; alpha7 Nicotinic Acetylcholine Receptor/metabolism

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Skocz do pozycji: 6.

Tytuł:: Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal.
Autorzy:: Jackson A; Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA, USA. .
Papke RL; Department of Pharmacology and Therapeutics, University of Florida, PO Box 100267, Gainesville, FL, 32610-0267, USA.
Damaj MI; Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA, USA.; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2018 Jul; Vol. 235 (7), pp. 1897-1905. Date of Electronic Publication: 2018 Mar 16.
Typ publikacji:: Journal Article
MeSH Terms:: Disease Models, Animal*
Mecamylamine/*administration & dosage
Nicotine/*administration & dosage
Nicotinic Antagonists/*administration & dosage
Substance Withdrawal Syndrome/*physiopathology
alpha7 Nicotinic Acetylcholine Receptor/*physiology
Animals ; Benzamides/administration & dosage ; Bridged Bicyclo Compounds/administration & dosage ; Dose-Response Relationship, Drug ; Infusion Pumps ; Male ; Mice ; Mice, Inbred ICR ; Nicotine/adverse effects ; Nicotinic Agonists/administration & dosage ; Substance Withdrawal Syndrome/etiology ; Substance Withdrawal Syndrome/psychology ; alpha7 Nicotinic Acetylcholine Receptor/agonists ; alpha7 Nicotinic Acetylcholine Receptor/antagonists & inhibitors

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Skocz do pozycji: 7.

Tytuł:: α9- and α7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line.
Autorzy:: Mucchietto V; CNR, Institute of Neuroscience, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy.
Fasoli F; CNR, Institute of Neuroscience, Milan, Italy.
Pucci S; CNR, Institute of Neuroscience, Milan, Italy.
Moretti M; CNR, Institute of Neuroscience, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy.
Benfante R; CNR, Institute of Neuroscience, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy.
Maroli A; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy.
Di Lascio S; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy.
Bolchi C; Department of Pharmaceutical Science, Università degli Studi di Milano, Milan, Italy.
Pallavicini M; Department of Pharmaceutical Science, Università degli Studi di Milano, Milan, Italy.
Dowell C; Department of Biology, University of Utah, Salt Lake City, UT, USA.
McIntosh M; Department of Biology, University of Utah, Salt Lake City, UT, USA.; George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, UT, USA.; Department of Psychiatry, University of Utah, Salt Lake City, UT, USA.
Clementi F; CNR, Institute of Neuroscience, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy.
Gotti C; CNR, Institute of Neuroscience, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2018 Jun; Vol. 175 (11), pp. 1957-1972. Date of Electronic Publication: 2017 Sep 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenocarcinoma/*drug therapy
Lung Neoplasms/*drug therapy
Nicotine/*pharmacology
Receptors, Nicotinic/*metabolism
alpha7 Nicotinic Acetylcholine Receptor/*antagonists & inhibitors
A549 Cells ; Adenocarcinoma/metabolism ; Adenocarcinoma/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Quaternary Ammonium Compounds/pharmacology ; Stilbenes/pharmacology ; Structure-Activity Relationship ; alpha7 Nicotinic Acetylcholine Receptor/metabolism

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Skocz do pozycji: 8.

Tytuł:: Wheel running during chronic nicotine exposure is protective against mecamylamine-precipitated withdrawal and up-regulates hippocampal α7 nACh receptors in mice.
Autorzy:: Keyworth H; School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Georgiou P; School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Zanos P; School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Rueda AV; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Chen Y; School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.; Institute of Psychiatry, Psychology and Neuroscience, Division of Academic Psychiatry, King's College London, London, UK.
Kitchen I; School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Camarini R; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Cropley M; School of Psychology, Faculty of Health and Medical Sciences, University of Surrey, Surrey, UK.
Bailey A; School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.; Institute of Medical and Biomedical Education, St George's University of London, London, UK.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2018 Jun; Vol. 175 (11), pp. 1928-1943. Date of Electronic Publication: 2017 Dec 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mecamylamine/*antagonists & inhibitors
Nicotine/*pharmacology
Protective Agents/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Animals ; Male ; Mecamylamine/pharmacology ; Mice ; Mice, Inbred C57BL ; Nicotine/administration & dosage ; Protective Agents/administration & dosage ; Up-Regulation/drug effects ; alpha7 Nicotinic Acetylcholine Receptor/antagonists & inhibitors

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Skocz do pozycji: 9.

Tytuł:: Nicotine Changes Airway Epithelial Phenotype and May Increase the SARS-COV-2 Infection Severity.
Autorzy:: Lupacchini L; Molecular and Cellular Neurobiology, IRCSS San Raffaele Pisana, Via di Val Cannuta, 247, I-00166 Rome, Italy.
Maggi F; Department of Medicine and Surgery, and Laboratory of Clinical Microbiology, University of Insubria, ASST dei Sette Laghi, viale Luigi Borri 57, I-21100 Varese, Italy.
Tomino C; Scientific Direction, IRCSS San Raffaele Pisana, Via di Val Cannuta, 247, I-00166 Rome, Italy.
De Dominicis C; Molecular and Cellular Neurobiology, IRCSS San Raffaele Pisana, Via di Val Cannuta, 247, I-00166 Rome, Italy.
Mollinari C; Institute of Translational Pharmacology, National Research Council, Via Fosso del Cavaliere 100, 00133 Rome, Italy.; Department of Neuroscience, Istituto Superiore di Sanità, Viale Regina Elena 299, I-00161 Rome, Italy.
Fini M; Scientific Direction, IRCSS San Raffaele Pisana, Via di Val Cannuta, 247, I-00166 Rome, Italy.
Bonassi S; Clinical and Molecular Epidemiology, IRCSS San Raffaele Pisana, Via di Val Cannuta, 247, I-00166 Rome, Italy.; Department of Human Sciences and Quality of Life Promotion San Raffaele University, Via di Val Cannuta, 247, I-00166 Rome, Italy.
Merlo D; Department of Neuroscience, Istituto Superiore di Sanità, Viale Regina Elena 299, I-00161 Rome, Italy.
Russo P; Clinical and Molecular Epidemiology, IRCSS San Raffaele Pisana, Via di Val Cannuta, 247, I-00166 Rome, Italy.; Department of Human Sciences and Quality of Life Promotion San Raffaele University, Via di Val Cannuta, 247, I-00166 Rome, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Dec 28; Vol. 26 (1). Date of Electronic Publication: 2020 Dec 28.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19/*pathology
Epithelial Cells/*drug effects
Nicotine/*adverse effects
Respiratory System/*drug effects
Angiotensin-Converting Enzyme 2/metabolism ; COVID-19/virology ; Cell Line ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Epithelial Cells/virology ; Humans ; Receptors, Nicotinic/metabolism ; Respiratory System/virology ; SARS-CoV-2/pathogenicity ; Severity of Illness Index ; Signal Transduction/drug effects ; Smoking/adverse effects ; alpha7 Nicotinic Acetylcholine Receptor/metabolism

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Skocz do pozycji: 10.

Tytuł:: Nicotine stimulates ion transport via metabotropic β4 subunit containing nicotinic ACh receptors.
Autorzy:: Kumar P; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
Scholze P; Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Vienna, Austria.
Fronius M; Department of Physiology and HeartOtago, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Krasteva-Christ G; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
Hollenhorst MI; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2020 Dec; Vol. 177 (24), pp. 5595-5608. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Nicotine*/pharmacology
Receptors, Nicotinic*
Acetylcholine ; Animals ; Dihydro-beta-Erythroidine ; Mecamylamine ; Mice ; Nicotinic Agonists ; Nicotinic Antagonists/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Component of nicotine-induced intracellular calcium elevation mediated through α3- and α5-containing nicotinic acetylcholine receptors are regulated by cyclic AMP in SH-SY 5Y cells.
Autorzy:: Takahashi T; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.; Department of Dental Anesthesiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yoshida T; Department of Neurophysiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Harada K; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Miyagi T; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Hashimoto K; Department of Neurophysiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Hide I; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Tanaka S; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Irifune M; Department of Dental Anesthesiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Sakai N; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Nov 30; Vol. 15 (11), pp. e0242349. Date of Electronic Publication: 2020 Nov 30 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Calcium/*metabolism
Cyclic AMP/*metabolism
Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
Receptors, Nicotinic/*metabolism
Cell Line ; Humans ; alpha7 Nicotinic Acetylcholine Receptor/metabolism

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Skocz do pozycji: 12.

Tytuł:: Nicotine stimulates collagen type I expression in lung via α7 nicotinic acetylcholine receptors.
Autorzy:: Vicary GW; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY, USA.
Ritzenthaler JD; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Disorders, University of Louisville School of Medicine, 550 South Jackson Street (3rd floor), Louisville, KY, USA.
Panchabhai TS; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Disorders, University of Louisville School of Medicine, 550 South Jackson Street (3rd floor), Louisville, KY, USA.
Torres-González E; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Disorders, University of Louisville School of Medicine, 550 South Jackson Street (3rd floor), Louisville, KY, USA.
Roman J; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY, USA. .; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Disorders, University of Louisville School of Medicine, 550 South Jackson Street (3rd floor), Louisville, KY, USA. .; Louisville Robley Rex Veterans Affairs Medical Center, Louisville, KY, USA. .; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2017 Jun 02; Vol. 18 (1), pp. 115. Date of Electronic Publication: 2017 Jun 02.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Collagen Type I/*metabolism
Extracellular Matrix/*drug effects
Fibroblasts/*drug effects
Lung/*drug effects
Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Animals ; Cell Proliferation/drug effects ; Collagen Type I/genetics ; Dose-Response Relationship, Drug ; Extracellular Matrix/metabolism ; Extracellular Matrix/pathology ; Female ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Humans ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Lung/metabolism ; Lung/pathology ; Mice, Inbred C57BL ; Mice, Knockout ; RNA Interference ; Time Factors ; Transfection ; U937 Cells ; Up-Regulation ; alpha7 Nicotinic Acetylcholine Receptor/genetics ; alpha7 Nicotinic Acetylcholine Receptor/metabolism

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Skocz do pozycji: 13.

Tytuł:: Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice.
Autorzy:: Higa KK; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Grim A; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Kamenski ME; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
van Enkhuizen J; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Zhou X; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.; Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA, 92037, USA.
Li K; Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Naviaux JC; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Wang L; Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Naviaux RK; Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Geyer MA; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.; Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA, 92037, USA.
Markou A; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Young JW; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA. .; Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA, 92037, USA. .; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2017 May; Vol. 234 (9-10), pp. 1573-1586. Date of Electronic Publication: 2017 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Attention/*physiology
Nicotine/*administration & dosage
Nicotine/*adverse effects
Psychomotor Performance/*physiology
Substance Withdrawal Syndrome/*metabolism
alpha7 Nicotinic Acetylcholine Receptor/*deficiency
Animals ; Attention/drug effects ; Choice Behavior/drug effects ; Choice Behavior/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Psychomotor Performance/drug effects ; Substance Withdrawal Syndrome/psychology ; Synaptosomes/drug effects ; Synaptosomes/metabolism ; alpha7 Nicotinic Acetylcholine Receptor/agonists

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Tytuł:: Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.
Autorzy:: Lykhmus O; Palladin Institute of Biochemistry, 01030 Kyiv, Ukraine.
Kalashnyk O; Palladin Institute of Biochemistry, 01030 Kyiv, Ukraine.
Uspenska K; Palladin Institute of Biochemistry, 01030 Kyiv, Ukraine.
Horid'ko T; Palladin Institute of Biochemistry, 01030 Kyiv, Ukraine.
Kosyakova H; Palladin Institute of Biochemistry, 01030 Kyiv, Ukraine.
Komisarenko S; Palladin Institute of Biochemistry, 01030 Kyiv, Ukraine.
Skok M; Palladin Institute of Biochemistry, 01030 Kyiv, Ukraine.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2020 Feb 03; Vol. 10 (2). Date of Electronic Publication: 2020 Feb 03.
Typ publikacji:: Journal Article
MeSH Terms:: Memory, Episodic*
Brain/*drug effects
Ethanolamines/*pharmacology
Mitochondria/*drug effects
Nicotine/*pharmacology
Stearic Acids/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*genetics
Animals ; Behavior, Animal ; Brain/metabolism ; Cytochromes c/metabolism ; Enzyme-Linked Immunosorbent Assay ; Interleukin-6/metabolism ; Lipids/chemistry ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism

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Tytuł:: Impact of modulation of the α7 nicotinic acetylcholine receptor on nicotine reward in the mouse conditioned place preference test.
Autorzy:: Jackson A; Department of Psychiatry, Yale School of Medicine, 34 Park St., New Haven, CT, 06519, USA. .
Alkhlaif Y; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, 23298-0613, USA.
Papke RL; Department of Pharmacology and Therapeutics, University of Florida, PO Box 100267, Gainesville, FL, 32610-0267, USA.
Brunzell DH; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, 23298-0613, USA.
Damaj MI; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, 23298-0613, USA.; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2019 Dec; Vol. 236 (12), pp. 3593-3599. Date of Electronic Publication: 2019 Jul 13.
Typ publikacji:: Journal Article
MeSH Terms:: Reward*
Conditioning, Classical/*physiology
Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*agonists
alpha7 Nicotinic Acetylcholine Receptor/*physiology
Animals ; Conditioning, Classical/drug effects ; Dose-Response Relationship, Drug ; Male ; Mice ; Mice, Inbred ICR

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Tytuł:: Nicotinic activity layer specifically modulates synaptic potentiation in the mouse insular cortex.
Autorzy:: Toyoda H; Department of Oral Physiology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, 565-0871, Japan.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2019 Aug; Vol. 50 (3), pp. 2211-2223. Date of Electronic Publication: 2018 Feb 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cerebral Cortex/*physiology
Nicotine/*pharmacology
Receptors, Nicotinic/*physiology
Synapses/*physiology
Synaptic Transmission/*physiology
Acetylcholine/pharmacology ; Animals ; Cerebral Cortex/cytology ; Cerebral Cortex/drug effects ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Nicotinic Agonists/pharmacology ; Synapses/drug effects ; Synaptic Transmission/drug effects

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Tytuł:: The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model.
Autorzy:: Šimurda J; Department of Physiology, Faculty of Medicine, Masaryk University, Kamenice, Brno, Czech Republic.
Šimurdová M; Department of Physiology, Faculty of Medicine, Masaryk University, Kamenice, Brno, Czech Republic.
Bébarová M; Department of Physiology, Faculty of Medicine, Masaryk University, Kamenice, Brno, Czech Republic.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Oct 10; Vol. 14 (10), pp. e0223448. Date of Electronic Publication: 2019 Oct 10 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetylcholine/*pharmacology
Ethanol/*pharmacology
G Protein-Coupled Inwardly-Rectifying Potassium Channels/*metabolism
Ion Channel Gating/*drug effects
Nicotine/*pharmacology
Computer Simulation ; Models, Biological ; Time Factors

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Skocz do pozycji: 18.

Tytuł:: Interactions of Glutamatergic Neurotransmission and Brain-Derived Neurotrophic Factor in the Regulation of Behaviors after Nicotine Administration.
Autorzy:: Kim J; Department of Biological Sciences, Pusan National University, 63-2 Busandaehak-ro, Geumjeong-gu, Busan 46241, Korea. .
Yang JH; Department of Biological Sciences, Pusan National University, 63-2 Busandaehak-ro, Geumjeong-gu, Busan 46241, Korea. .
Ryu IS; Department of Biological Sciences, Pusan National University, 63-2 Busandaehak-ro, Geumjeong-gu, Busan 46241, Korea. .; Research Center for Safety Pharmacology, Korea Institute of Toxicology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, Korea. .
Sohn S; Department of Biological Sciences, Pusan National University, 63-2 Busandaehak-ro, Geumjeong-gu, Busan 46241, Korea. .
Kim S; Department of Biological Sciences, Pusan National University, 63-2 Busandaehak-ro, Geumjeong-gu, Busan 46241, Korea. .
Choe ES; Department of Biological Sciences, Pusan National University, 63-2 Busandaehak-ro, Geumjeong-gu, Busan 46241, Korea. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Jun 16; Vol. 20 (12). Date of Electronic Publication: 2019 Jun 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Behavior*
Synaptic Transmission*
Brain-Derived Neurotrophic Factor/*metabolism
GABAergic Neurons/*drug effects
GABAergic Neurons/*physiology
Nicotine/*administration & dosage
Animals ; Glutamic Acid/biosynthesis ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/physiopathology ; Humans ; Nerve Growth Factors/metabolism ; Receptor, trkB/metabolism ; Receptors, Glutamate/metabolism ; Signal Transduction ; alpha7 Nicotinic Acetylcholine Receptor/agonists

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Skocz do pozycji: 19.

Tytuł:: Alpha7 nicotinic acetylcholine receptor is required for amyloid pathology in brain endothelial cells induced by Glycoprotein 120, methamphetamine and nicotine.
Autorzy:: Liu L; Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.; Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA90027, USA.
Yu J; Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA90027, USA.; School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, 510515, China.
Li L; School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, 510515, China.; Department of Clinical Laboratory, Kunming Children's Hospital, Kunming Medical University, Kunming, Yunnan 650034, China.
Zhang B; Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA90027, USA.; School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, 510515, China.
Liu L; Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Wu CH; Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA90027, USA.
Jong A; Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA90027, USA.
Mao DA; Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Huang SH; Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA90027, USA.; School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, 510515, China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2017 Jan 11; Vol. 7, pp. 40467. Date of Electronic Publication: 2017 Jan 11.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Amyloid/*metabolism
Brain/*pathology
Endothelial Cells/*metabolism
HIV Envelope Protein gp120/*pharmacology
Methamphetamine/*pharmacology
Nicotine/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Alzheimer Disease/blood ; Alzheimer Disease/cerebrospinal fluid ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/metabolism ; Animals ; Biomarkers/metabolism ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/injuries ; Blood-Brain Barrier/metabolism ; Blood-Brain Barrier/pathology ; Cell Movement/drug effects ; Cellular Senescence/drug effects ; Endothelial Cells/drug effects ; HL-60 Cells ; Humans ; Mice, Inbred C57BL ; Monocytes/drug effects ; Monocytes/metabolism ; Protein Transport/drug effects ; Receptor for Advanced Glycation End Products/metabolism ; S100 Proteins/metabolism ; Time Factors ; alpha7 Nicotinic Acetylcholine Receptor/antagonists & inhibitors

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Tytuł:: Stimulation of Alpha7 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Upregulation of MMP, MCP-1, and RANTES through Modulating ERK1/2/AP-1 Signaling Pathway in RAW264.7 and MOVAS Cells.
Autorzy:: Liu L; Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, Shanghai Jiaotong University, Shanghai, China.; Department of Cardiology, Yancheng First People's Hospital, The Fourth Affiliated Hospital of Nantong Medical University, Jiangsu, China.
Wu H; Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, Shanghai Jiaotong University, Shanghai, China.
Cao Q; Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, Shanghai Jiaotong University, Shanghai, China.
Guo Z; Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, Shanghai Jiaotong University, Shanghai, China.
Ren A; Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, Shanghai Jiaotong University, Shanghai, China.
Dai Q; Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, Shanghai Jiaotong University, Shanghai, China.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2017; Vol. 2017, pp. 2401027. Date of Electronic Publication: 2017 Nov 16.
Typ publikacji:: Journal Article
MeSH Terms:: Chemokine CCL2/*genetics
Chemokine CCL5/*genetics
Extracellular Signal-Regulated MAP Kinases/*physiology
Matrix Metalloproteinases/*genetics
Nicotine/*pharmacology
Signal Transduction/*physiology
Transcription Factor AP-1/*physiology
alpha7 Nicotinic Acetylcholine Receptor/*physiology
Animals ; Benzamides/pharmacology ; Bridged Bicyclo Compounds/pharmacology ; Butadienes/pharmacology ; JNK Mitogen-Activated Protein Kinases/metabolism ; MAP Kinase Signaling System/physiology ; Mice ; Nitriles/pharmacology ; Phosphorylation ; RAW 264.7 Cells ; Up-Regulation/physiology ; alpha7 Nicotinic Acetylcholine Receptor/agonists

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