Temat: "activated" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The effects of restraint stress on ceramide metabolism disorders in the rat liver: the role of CerS6 in hepatocyte injury.
Autorzy:: Liu Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.; Department of Forensic Medicine, College of Medicine, Nantong University, Nantong, 226000, China.
Sun Z; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Sun Q; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Wang L; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Wang C; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Li Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Ma C; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Shi W; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Zhang G; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.; Hebei Province Laboratory of Experimental Animal, Shijiazhuang, 050017, China.
Dong Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Zhang X; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China. .
Cong B; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China. .; Hainan Tropical Forensic Medicine Academician Workstation, Haikou, 571199, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2024 Mar 02; Vol. 23 (1), pp. 68. Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:: Journal Article
MeSH Terms:: AMP-Activated Protein Kinases*/metabolism
Tandem Mass Spectrometry*
Rats ; Animals ; Chromatography, Liquid ; Ceramides/metabolism ; Hepatocytes/metabolism ; Liver/metabolism ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism ; Apoptosis ; Sphingosine N-Acyltransferase/genetics ; Sphingosine N-Acyltransferase/metabolism

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Skocz do pozycji: 2.

Tytuł:: The Role of the Dysregulated JNK Signaling Pathway in the Pathogenesis of Human Diseases and Its Potential Therapeutic Strategies: A Comprehensive Review.
Autorzy:: Yan H; Department of Ultrasound, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
He L; Department of Ultrasound, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Lv; Department of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Yang J; Cancer Center and State Key Laboratory of Biotherapy, Department of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.
Yuan Z; Cancer Center and State Key Laboratory of Biotherapy, Department of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Feb 19; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:: Journal Article; Review
MeSH Terms:: MAP Kinase Signaling System*
Mitogen-Activated Protein Kinases*/metabolism
Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; Cell Differentiation

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Skocz do pozycji: 3.

Tytuł:: Sesamin attenuates UVA-induced keratinocyte injury via inhibiting ASK-1-JNK/p38 MAPK pathways.
Autorzy:: Li H; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Zhu L; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Weng Z; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Fu H; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Liu J; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Mao Q; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Li W; The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Ding B; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Cao Y; The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.; Pokaż więcej
Źródło:: Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Jan; Vol. 23 (1), pp. 316-325. Date of Electronic Publication: 2023 Aug 06.
Typ publikacji:: Journal Article
MeSH Terms:: p38 Mitogen-Activated Protein Kinases*/metabolism
p38 Mitogen-Activated Protein Kinases*/pharmacology
Matrix Metalloproteinase 9*/metabolism
Humans ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/pharmacology ; Matrix Metalloproteinase 1/metabolism ; Keratinocytes/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/pharmacology ; JNK Mitogen-Activated Protein Kinases/metabolism ; JNK Mitogen-Activated Protein Kinases/pharmacology ; Apoptosis ; Superoxide Dismutase/metabolism ; Ultraviolet Rays/adverse effects

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Skocz do pozycji: 4.

Tytuł:: Mitochondrial p38 Mitogen-Activated Protein Kinase: Insights into Its Regulation of and Role in LONP1-Deficient Nematodes.
Autorzy:: Taouktsi E; Laboratory of Molecular Genetics of Aging, Biomedical Research Foundation of the Academy of Athens, Center of Basic Research, 11527 Athens, Greece.; Department of Biotechnology, Agricultural University of Athens, 11855 Athens, Greece.
Kyriakou E; Laboratory of Molecular Genetics of Aging, Biomedical Research Foundation of the Academy of Athens, Center of Basic Research, 11527 Athens, Greece.
Voulgaraki E; Laboratory of Molecular Genetics of Aging, Biomedical Research Foundation of the Academy of Athens, Center of Basic Research, 11527 Athens, Greece.
Verganelakis D; Laboratory of Molecular Genetics of Aging, Biomedical Research Foundation of the Academy of Athens, Center of Basic Research, 11527 Athens, Greece.; Department of Biological Applications & Technology, University of Ioannina, 45500 Ioannina, Greece.
Krokou S; Laboratory of Molecular Genetics of Aging, Biomedical Research Foundation of the Academy of Athens, Center of Basic Research, 11527 Athens, Greece.
Rigas S; Department of Biotechnology, Agricultural University of Athens, 11855 Athens, Greece.
Voutsinas GE; Laboratory of Molecular Carcinogenesis and Rare Disease Genetics, Institute of Biosciences and Applications, National Center for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15341 Athens, Greece.
Syntichaki P; Laboratory of Molecular Genetics of Aging, Biomedical Research Foundation of the Academy of Athens, Center of Basic Research, 11527 Athens, Greece.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 07; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:: Journal Article
MeSH Terms:: Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Mitogen-Activated Protein Kinase 14*/metabolism
Animals ; Caenorhabditis elegans/metabolism ; Cyclic AMP Response Element-Binding Protein/metabolism ; Mammals/metabolism ; Mitogen-Activated Protein Kinases/genetics ; Mitogen-Activated Protein Kinases/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism

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Skocz do pozycji: 5.

Tytuł:: Dual-Specificity Phosphatases in Regulation of Tumor-Associated Macrophage Activity.
Autorzy:: Patysheva MR; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia.
Prostakishina EA; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia.
Budnitskaya AA; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Genetic Technologies, Siberian State Medical University, 634050 Tomsk, Russia.
Bragina OD; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia.
Kzhyshkowska JG; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Genetic Technologies, Siberian State Medical University, 634050 Tomsk, Russia.; Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Mannheim Institute of Innate Immunosciences (MI3), University of Heidelberg, 68167 Mannheim, Germany.; German Red Cross Blood Service Baden-Württemberg-Hessen, 69117 Mannheim, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 16; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Dual-Specificity Phosphatases*/metabolism
Mitogen-Activated Protein Kinases*/metabolism
Phosphoprotein Phosphatases/metabolism ; Tumor-Associated Macrophages/metabolism ; Protein Tyrosine Phosphatases/metabolism ; Mitogens ; Phosphorylation ; Protein Kinases/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism ; Dual Specificity Phosphatase 1/metabolism

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Skocz do pozycji: 6.

Tytuł:: Cooling of male rat skeletal muscle during endurance-like contraction attenuates contraction-induced PGC-1α mRNA expression.
Autorzy:: Hoshino D; Bioscience and Technology Program, Department of Engineering Science, The University of Electro-Communications, Chofu, Tokyo, Japan.
Wada R; Bioscience and Technology Program, Department of Engineering Science, The University of Electro-Communications, Chofu, Tokyo, Japan.
Mori Y; Bioscience and Technology Program, Department of Engineering Science, The University of Electro-Communications, Chofu, Tokyo, Japan.
Takeda R; Bioscience and Technology Program, Department of Engineering Science, The University of Electro-Communications, Chofu, Tokyo, Japan.
Nonaka Y; Institute of Liberal Arts and Science, Kanazawa University, Kanazawa, Japan.
Kano R; Bioscience and Technology Program, Department of Engineering Science, The University of Electro-Communications, Chofu, Tokyo, Japan.
Takagi R; Ritsumeikan Global Innovation Research Organization, Ritsumeikan University, Kusatsu, Shiga, Japan.
Kano Y; Bioscience and Technology Program, Department of Engineering Science, The University of Electro-Communications, Chofu, Tokyo, Japan.; Pokaż więcej
Źródło:: Physiological reports [Physiol Rep] 2023 Nov; Vol. 11 (21), pp. e15867.
Typ publikacji:: Journal Article
MeSH Terms:: AMP-Activated Protein Kinases*/metabolism
Vascular Endothelial Growth Factor A*/genetics
Vascular Endothelial Growth Factor A*/metabolism
Animals ; Male ; Rats ; Glycogen/metabolism ; Ice ; Muscle Contraction ; Muscle, Skeletal/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; RNA, Messenger/metabolism

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Skocz do pozycji: 7.

Tytuł:: Photoprotective Effects of Epigallocatechin Gallate on Ultraviolet-Induced Zebrafish and Human Skin Fibroblasts Cells.
Autorzy:: Zhang J; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Xu Y; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Ruan X; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Zhang T; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Zi M; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Zhang Q; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2024 Jan 24; Vol. 2024, pp. 7887678. Date of Electronic Publication: 2024 Jan 24 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Zebrafish*
Mitogen-Activated Protein Kinases*/metabolism
Catechin/*analogs & derivatives
Animals ; Humans ; NF-kappa B/metabolism ; Interleukin-6/metabolism ; Transcription Factor AP-1/metabolism ; Ultraviolet Rays/adverse effects ; Tumor Necrosis Factor-alpha/metabolism ; Skin/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism ; Fibroblasts/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 8.

Tytuł:: Resveratrol improves the prognosis of rats after spinal cord injury by inhibiting mitogen-activated protein kinases signaling pathway.
Autorzy:: Kan S; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Liu C; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhao X; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Feng S; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhu H; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Ma B; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhou M; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Fu X; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Hu W; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhu R; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Nov 13; Vol. 13 (1), pp. 19723. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mitogen-Activated Protein Kinases*/metabolism
Spinal Cord Injuries*
Rats ; Animals ; Rats, Sprague-Dawley ; Resveratrol/pharmacology ; Resveratrol/therapeutic use ; Tumor Necrosis Factor-alpha/pharmacology ; Interleukin-6/pharmacology ; Signal Transduction ; p38 Mitogen-Activated Protein Kinases/metabolism ; Prognosis ; Anti-Inflammatory Agents/pharmacology ; Spinal Cord/metabolism ; Recovery of Function

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Skocz do pozycji: 9.

Tytuł:: Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells.
Autorzy:: Akasaka Y; Department of Biomedical Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Hasei S; Department of Biomedical Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Ohata Y; Department of Biomedical Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Kanna M; Department of Biomedical Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Nakatsu Y; Department of Biomedical Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Sakoda H; Department of Bioregulatory Sciences, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan.
Fujishiro M; Division of Diabetes and Metabolic Diseases, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Kushiyama A; Department of Pharmacotherapy, Meiji Pharmaceutical University, Kiyose 204-8588, Japan.
Ono H; Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Matsubara A; Department of Urology, JA Hiroshima General Hospital, Hatsukaichi 738-8503, Japan.
Hinata N; Department of Urology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Asano T; Department of Biomedical Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Yamamotoya T; Department of Biomedical Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 06; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:: Journal Article
MeSH Terms:: AMP-Activated Protein Kinases*/metabolism
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/metabolism
Male ; Humans ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Prostate-Specific Antigen/genetics ; Prostate-Specific Antigen/metabolism ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Prostate/metabolism ; HEK293 Cells ; AMP-Activated Protein Kinase Kinases ; TOR Serine-Threonine Kinases/metabolism ; Cell Proliferation ; Cell Line, Tumor

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Skocz do pozycji: 10.

Tytuł:: Mitogen-Activated Protein Kinase and Exploratory Nuclear Receptor Crosstalk in Cancer Immunotherapy.
Autorzy:: Burgermeister E; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 26; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 26.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Mitogen-Activated Protein Kinases*/metabolism
Neoplasms*/therapy
Humans ; p38 Mitogen-Activated Protein Kinases ; JNK Mitogen-Activated Protein Kinases ; Receptors, Cytoplasmic and Nuclear ; Immunotherapy

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Skocz do pozycji: 11.

Tytuł:: Differential Modulation of the Phosphoproteome by the MAP Kinases Isoforms p38α and p38β.
Autorzy:: Melamed Kadosh D; Faculty of Biology, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
Beenstock J; Department of Biological Chemistry, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Engelberg D; Department of Biological Chemistry, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.; Singapore-HUJ Alliance for Research and Enterprise, Mechanisms of Liver Inflammatory Diseases Program, National University of Singapore, Singapore 138602, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117456, Singapore.
Admon A; Faculty of Biology, Technion-Israel Institute of Technology, Haifa 3200003, Israel.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 04; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:: Journal Article
MeSH Terms:: Proteome*/metabolism
Mitogen-Activated Protein Kinase 14*/genetics
Mitogen-Activated Protein Kinase 14*/metabolism
Animals ; Humans ; Mice ; Tumor Suppressor Protein p53/metabolism ; Fibroblasts/metabolism ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Phosphorylation ; p38 Mitogen-Activated Protein Kinases/metabolism

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Skocz do pozycji: 12.

Tytuł:: Microglia and p38 MAPK Inhibitors Suppress Development of Mechanical Allodynia in Both Sexes in a Mouse Model of Antiretroviral-Induced Neuropathic Pain.
Autorzy:: Alhadlaq MW; Molecular Biology Program, College of Graduate Studies, Kuwait University, Safat, Kuwait City 13110, Kuwait.; Department of Pharmacology and Therapeutics, College of Pharmacy, Kuwait University, Safat, Kuwait City 13110, Kuwait.
Masocha W; Department of Pharmacology and Therapeutics, College of Pharmacy, Kuwait University, Safat, Kuwait City 13110, Kuwait.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 15; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 15.
Typ publikacji:: Journal Article
MeSH Terms:: Mitogen-Activated Protein Kinase 14*
Neuralgia*/chemically induced
Neuralgia*/drug therapy
HIV Infections*
Female ; Male ; Animals ; Mice ; p38 Mitogen-Activated Protein Kinases ; Hyperalgesia/chemically induced ; Hyperalgesia/drug therapy ; Microglia ; Anti-Retroviral Agents ; Disease Models, Animal

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Skocz do pozycji: 13.

Tytuł:: Repeated Rounds of Gonadotropin Stimulation Induce Imbalance in the Antioxidant Machinery and Activation of Pro-Survival Proteins in Mouse Oviducts.
Autorzy:: Di Nisio V; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, SE-14186 Stockholm, Sweden.; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, SE-14186 Stockholm, Sweden.
Antonouli S; Department of Clinical Chemistry, Faculty of Medicine, University of Ioannina, PC-45110 Ioannina, Greece.
Colafarina S; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Zarivi O; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Rossi G; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Cecconi S; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Poma AMG; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 26; Vol. 24 (11). Date of Electronic Publication: 2023 May 26.
Typ publikacji:: Journal Article
MeSH Terms:: Mitogen-Activated Protein Kinases*/metabolism
Antioxidants*
Mice ; Animals ; JNK Mitogen-Activated Protein Kinases ; HSP27 Heat-Shock Proteins ; p38 Mitogen-Activated Protein Kinases ; Apoptosis ; Mitogen-Activated Protein Kinase 8 ; DNA, Mitochondrial

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Skocz do pozycji: 14.

Tytuł:: Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells.
Autorzy:: Lynch KD; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Iverson DT; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Bachhav NK; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Call MR; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Yue GE; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Prasad B; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Clarke JD; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 06; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:: Journal Article
MeSH Terms:: Mitogen-Activated Protein Kinases*/metabolism
Chemical and Drug Induced Liver Injury*/metabolism
Humans ; Microcystins/toxicity ; Phosphorylation ; Phosphoprotein Phosphatases/metabolism ; Cytoskeleton/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism

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Skocz do pozycji: 15.

Tytuł:: Novel Tryptanthrin Derivatives with Selectivity as c -Jun N-Terminal Kinase (JNK) 3 Inhibitors.
Autorzy:: Schepetkin IA; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
Karpenko OS; O.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, 65080 Odesa, Ukraine.
Kovrizhina AR; Kizhner Research Center, Tomsk Polytechnic University, Tomsk 634050, Russia.
Kirpotina LN; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
Khlebnikov AI; Kizhner Research Center, Tomsk Polytechnic University, Tomsk 634050, Russia.
Chekal SI; Department of Organic Chemistry, Faculty of Chemistry and Pharmacy, Odesa I.I. Mechnikov National University, 65082 Odesa, Ukraine.
Radudik AV; O.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, 65080 Odesa, Ukraine.; Department of Organic Chemistry, Faculty of Chemistry and Pharmacy, Odesa I.I. Mechnikov National University, 65082 Odesa, Ukraine.
Shybinska MO; O.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, 65080 Odesa, Ukraine.
Quinn MT; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jun 16; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:: Journal Article
MeSH Terms:: JNK Mitogen-Activated Protein Kinases*/metabolism
Lipopolysaccharides*/pharmacology
Mitogen-Activated Protein Kinase 8/metabolism ; Phosphorylation ; Oximes/pharmacology ; Oximes/chemistry

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Skocz do pozycji: 16.

Tytuł:: The angiotensin receptor neprilysin inhibitor LCZ696 attenuates renal fibrosis via ASK1/JNK/p38 MAPK-mediated apoptosis in unilateral ureteral obstruction.
Autorzy:: Ding J; Department of Nephrology, Yanbian University Hospital, Yanji, China.
Cui S; Department of Nephrology, Yanbian University Hospital, Yanji, China.; Department of Internal Medicine, Transplantation Research Center, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Li SY; Department of Nephrology, Yanbian University Hospital, Yanji, China.
Cui LY; Department of Nephrology, Yanbian University Hospital, Yanji, China.
Nan QY; Department of Intensive Care Unit, Yanbian University Hospital, Yanji, China.
Lin XJ; Department of Radionuclide Medicine, Yanbian University Hospital, Yanji, China.
Xuan MY; Department of Health Examination Central, Yanbian University, Yanji, China.
Jin J; Department of General Practice, Yanbian University Hospital, Yanji, China.
Piao SG; Department of Nephrology, Yanbian University Hospital, Yanji, China.
Jiang YJ; Department of Nephrology, Yanbian University Hospital, Yanji, China.
Zheng HL; Department of Nephrology, Yanbian University Hospital, Yanji, China.
Jin JZ; Department of Nephrology, Yanbian University Hospital, Yanji, China.
Chung BH; Department of Internal Medicine, Transplantation Research Center, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.; Department of Internal Medicine, Division of Nephrology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Yang CW; Department of Internal Medicine, Transplantation Research Center, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.; Department of Internal Medicine, Division of Nephrology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Cui JH; College of Pharmaceutical Sciences, Soochow University, Jiangsu Prov., Suzhou, China.
Li C; Department of Nephrology, Yanbian University Hospital, Yanji, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jun 13; Vol. 18 (6), pp. e0286903. Date of Electronic Publication: 2023 Jun 13 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ureteral Obstruction*/complications
Ureteral Obstruction*/drug therapy
Mitogen-Activated Protein Kinase 14*
Kidney Diseases*
Humans ; Animals ; Rats ; p38 Mitogen-Activated Protein Kinases ; Neprilysin ; Receptors, Angiotensin ; Hydrogen Peroxide ; MAP Kinase Kinase Kinase 5 ; Valsartan/pharmacology ; Antihypertensive Agents ; Antiviral Agents ; Apoptosis

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Skocz do pozycji: 17.

Tytuł:: Differential Functional Contribution of BK Channel Subunits to Aldosterone-Induced Channel Activation in Vascular Smooth Muscle and Eventual Cerebral Artery Dilation.
Autorzy:: Mysiewicz SC; Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Hawks SM; Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Bukiya AN; Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Dopico AM; Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38103, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 12; Vol. 24 (10). Date of Electronic Publication: 2023 May 12.
Typ publikacji:: Journal Article
MeSH Terms:: Large-Conductance Calcium-Activated Potassium Channels*
Aldosterone*/pharmacology
Mice ; Animals ; Large-Conductance Calcium-Activated Potassium Channel beta Subunits/genetics ; Muscle, Smooth, Vascular ; Dilatation ; Steroids/pharmacology ; Cerebral Arteries

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Skocz do pozycji: 18.

Tytuł:: Growth State-Dependent Activation of eNOS in Response to DHA: Involvement of p38 MAPK.
Autorzy:: Huang S; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB R2H 2A6, Canada.
Taylor CG; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB R2H 2A6, Canada.; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0W2, Canada.
Zahradka P; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB R2H 2A6, Canada.; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0W2, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 06; Vol. 24 (9). Date of Electronic Publication: 2023 May 06.
Typ publikacji:: Journal Article
MeSH Terms:: Nitric Oxide Synthase Type III*/metabolism
Mitogen-Activated Protein Kinase 14*/metabolism
Humans ; p38 Mitogen-Activated Protein Kinases/metabolism ; Docosahexaenoic Acids/pharmacology ; Docosahexaenoic Acids/metabolism ; Endothelial Cells/metabolism ; Phosphorylation ; Cells, Cultured

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Skocz do pozycji: 19.

Tytuł:: Omentin-1 promotes mitochondrial biogenesis via PGC1α-AMPK pathway in chondrocytes.
Autorzy:: Li Z; Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Zhang Y; Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Tian F; Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Wang Z; Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Song H; Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Chen H; Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Wu B; Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.; Pokaż więcej
Źródło:: Archives of physiology and biochemistry [Arch Physiol Biochem] 2023 Apr; Vol. 129 (2), pp. 291-297. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji:: Journal Article
MeSH Terms:: AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Chondrocytes*/metabolism
Adenosine Triphosphate/metabolism ; DNA, Mitochondrial/genetics ; DNA, Mitochondrial/metabolism ; Mitochondrial Proteins/genetics ; Organelle Biogenesis ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Lectins/pharmacology ; Cytokines/pharmacology ; GPI-Linked Proteins/pharmacology

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Skocz do pozycji: 20.

Tytuł:: Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1.
Autorzy:: Malik N; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Ferreira BI; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Hollstein PE; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Curtis SD; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Trefts E; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Weiser Novak S; Biophotonics Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Yu J; Bioinformatics Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Gilson R; Biophotonics Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Hellberg K; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Fang L; Biophotonics Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Sheridan A; Biophotonics Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Hah N; Next Generation Sequencing Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Shadel GS; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Manor U; Biophotonics Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Shaw RJ; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2023 Apr 21; Vol. 380 (6642), pp. eabj5559. Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:: Journal Article
MeSH Terms:: AMP-Activated Protein Kinases*/metabolism
Lysosomes*/metabolism
Mitochondria*
Organelle Biogenesis*
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Phosphorylation ; Protein Processing, Post-Translational ; Humans

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