Temat: "activation" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Role of Hemigraphis alternata in wound healing: metabolomic profiling and molecular insights into mechanisms.
Autorzy:: Devasahayam Arokia Balaya R; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India, 575018.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Palollathil A; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India, 575018.
Kumar STA; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India, 575018.
Chandrasekaran J; Department of Pharmacology, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Chennai, 600116, India.
Upadhyay SS; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India, 575018.
Parate SS; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India, 575018.
Sajida M; Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India.
Karthikkeyan G; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India, 575018.
Prasad TSK; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India, 575018. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 16; Vol. 14 (1), pp. 3872. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Wound Healing*/physiology
Platelet Activation*
Humans ; Metabolomics ; Plant Leaves/chemistry ; Molecular Docking Simulation

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Skocz do pozycji: 2.

Tytuł:: Mechanosensitive traction force generation is regulated by the neutrophil activation state.
Autorzy:: Witt H; Graduate Program in Pathobiology, Brown University, Providence, RI, 02912, USA. hadley_.; Division of Surgical Research, Department of Surgery, Rhode Island Hospital, Providence, RI, 02903, USA. hadley_.
Yan Z; School of Engineering, Brown University, Providence, RI, 02912, USA.
Henann D; School of Engineering, Brown University, Providence, RI, 02912, USA.
Franck C; Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Reichner J; Division of Surgical Research, Department of Surgery, Rhode Island Hospital, Providence, RI, 02903, USA. jonathan_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jul 09; Vol. 13 (1), pp. 11098. Date of Electronic Publication: 2023 Jul 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Neutrophil Activation*
Traction*
Humans ; Microscopy, Atomic Force ; Phagocytosis ; Neutrophils/physiology

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Skocz do pozycji: 3.

Tytuł:: Identification and elucidation of cross talk between SLAM Family Member 7 (SLAMF7) and Toll-like receptor (TLR) pathways in monocytes and macrophages.
Autorzy:: Choe U; Department of Nutrition and Food Science, University of Maryland, College Park, MD, 20742, USA.
Pham Q; U.S. Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD, 20705, USA.
Kim YS; Cancer Prevention Science Branch, Division of Cancer Prevention, NCI, Rockville, MD, 20850, USA.
Yu L; Department of Nutrition and Food Science, University of Maryland, College Park, MD, 20742, USA.
Wang TTY; U.S. Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD, 20705, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jul 07; Vol. 13 (1), pp. 11007. Date of Electronic Publication: 2023 Jul 07.
Typ publikacji:: Journal Article
MeSH Terms:: Macrophages*/metabolism
Monocytes*/metabolism
Signaling Lymphocytic Activation Molecule Family*/metabolism
Toll-Like Receptors*/metabolism
Humans ; Cytokines/metabolism ; Family ; Ligands ; Lipopolysaccharides ; RNA, Messenger/metabolism

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Skocz do pozycji: 4.

Tytuł:: Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics.
Autorzy:: Fernández DI; The Department of Biochemistry, CARIM, Maastricht University, 6229 ER, Maastricht, The Netherlands.; Platelet Proteomics Group, CiMUS, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Troitiño S; Platelet Proteomics Group, CiMUS, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Sobota V; IHU-LIRYC, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, 33604, Bordeaux, France.; Institut de Mathématiques de Bordeaux, UMR5251, University of Bordeaux, 33 405, Talence, France.
Tullemans BME; The Department of Biochemistry, CARIM, Maastricht University, 6229 ER, Maastricht, The Netherlands.; Synapse Research Institute, Kon. Emmaplein 7, 6217 KD, Maastricht, The Netherlands.
Zou J; The Department of Biochemistry, CARIM, Maastricht University, 6229 ER, Maastricht, The Netherlands.; Synapse Research Institute, Kon. Emmaplein 7, 6217 KD, Maastricht, The Netherlands.
van den Hurk H; Pivot Park Screening Centre, 5349 AB, Oss, The Netherlands.
García Á; Platelet Proteomics Group, CiMUS, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Honarnejad S; Pivot Park Screening Centre, 5349 AB, Oss, The Netherlands.
Kuijpers MJE; The Department of Biochemistry, CARIM, Maastricht University, 6229 ER, Maastricht, The Netherlands. .; Thrombosis Expertise Centre, Heart and Vascular Centre, Maastricht University Medical Centre+, 6229 HX, Maastricht, The Netherlands. .
Heemskerk JWM; The Department of Biochemistry, CARIM, Maastricht University, 6229 ER, Maastricht, The Netherlands. .; Synapse Research Institute, Kon. Emmaplein 7, 6217 KD, Maastricht, The Netherlands. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 14; Vol. 14 (1), pp. 6229. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Platelet Aggregation Inhibitors*/pharmacology
Calcium*/metabolism
Phenothiazines*
Humans ; Thrombin/metabolism ; Calcium Signaling ; Platelet Membrane Glycoproteins/metabolism ; Receptor, PAR-1/metabolism ; Blood Platelets/metabolism ; Platelet Activation ; Calcium, Dietary/pharmacology ; Platelet Aggregation

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Skocz do pozycji: 5.

Tytuł:: Inhibition of succinate dehydrogenase activity impairs human T cell activation and function.
Autorzy:: Nastasi C; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Willerlev-Olsen A; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Dalhoff K; MS-Omics, Vedbæk, Denmark.
Ford SL; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Gadsbøll AØ; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Buus TB; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Gluud M; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Danielsen M; MS-Omics, Vedbæk, Denmark.
Litman T; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; LEO Pharma A/S, Ballerup, Denmark.
Bonefeld CM; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Geisler C; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Ødum N; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark.
Woetmann A; LEO Foundation Skin Immunology Research Center & Department of Immunology and Microbiology, University of Copenhagen, Panum Institute, The Maersk tower, 07.12.76, Blegdamsvej 3C, 2200, Copenhagen, Denmark. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 14; Vol. 11 (1), pp. 1458. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Proliferation/*drug effects
Enzyme Inhibitors/*pharmacology
Gene Expression Regulation/*drug effects
Lymphocyte Activation/*drug effects
Succinate Dehydrogenase/*antagonists & inhibitors
T-Lymphocytes/*immunology
Cytokines/biosynthesis ; Cytokines/immunology ; Enzyme Activation/drug effects ; Enzyme Activation/immunology ; Gene Expression Regulation/immunology ; Humans ; Succinate Dehydrogenase/immunology

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Skocz do pozycji: 6.

Tytuł:: Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation.
Autorzy:: Silva IS; Laboratory of Inflammation and Proteases, Department of Pharmacology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Almeida AD; Laboratory of Inflammation and Proteases, Department of Pharmacology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Lima Filho ACM; Department of Physiology and Biophysics, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Fernandes-Braga W; Laboratory of Atherosclerosis and Nutritional Biochemistry (LABIN-UFMG), Department of Biochemistry and Immunology, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Barra A; Laboratory of Inflammation and Proteases, Department of Pharmacology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Oliveira HMC; Department of Morphology, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Cassali GD; Department of Pathology, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Capettini LSA; Laboratory of Vascular Biology, Department of Pharmacology, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Menezes GB; Department of Morphology, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Alvarez-Leite JI; Laboratory of Atherosclerosis and Nutritional Biochemistry (LABIN-UFMG), Department of Biochemistry and Immunology, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Leite MF; Department of Physiology and Biophysics, ICB/UFMG, Belo Horizonte, Minas Gerais, Brazil.
Klein A; Laboratory of Inflammation and Proteases, Department of Pharmacology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Dec 07; Vol. 13 (1), pp. 21637. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:: Journal Article
MeSH Terms:: NF-kappa B*/metabolism
Pneumonia*/chemically induced
Mice ; Animals ; Platelet Activating Factor/metabolism ; Receptor, PAR-2/genetics ; Receptor, PAR-2/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Aprotinin/metabolism ; Neutrophil Infiltration ; Transcriptional Activation

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Skocz do pozycji: 7.

Tytuł:: Artificial surface labelling of Escherichia coli with StrepTagII antigen to study how monoclonal antibodies drive complement-mediated killing.
Autorzy:: Muts RM; Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
den Boer MA; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University, 3584 CH, Utrecht, The Netherlands.; Netherlands Proteomic Center, 3584 CH, Utrecht, The Netherlands.
Bardoel BW; Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Aerts PC; Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
de Haas CJC; Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Heck AJR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University, 3584 CH, Utrecht, The Netherlands.; Netherlands Proteomic Center, 3584 CH, Utrecht, The Netherlands.
Rooijakkers SHM; Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Heesterbeek DAC; Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Nov 01; Vol. 13 (1), pp. 18836. Date of Electronic Publication: 2023 Nov 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Escherichia coli*/metabolism
Antibodies, Monoclonal*/metabolism
Complement System Proteins/metabolism ; Complement Membrane Attack Complex/metabolism ; Complement Activation ; Immunoglobulin G ; Antigens, Surface/metabolism ; Immunoglobulin M/metabolism

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Skocz do pozycji: 8.

Tytuł:: Expression of membrane Hsp90 is a molecular signature of T cell activation.
Autorzy:: Scarneo SA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Smith AP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Favret J; Bolder BioPath INC., Boulder, CO, 80301, USA.
O'Connell R; Bolder BioPath INC., Boulder, CO, 80301, USA.
Pickeral J; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA.
Yang KW; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Ferrari G; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA.
Loiselle DR; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Hughes PF; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Kulkarni MM; Department of Microbiology, Ohio State University, Columbus, OH, 43210, USA.
Gargesha M; BioInVision, Inc., Mayfield, OH, 44143, USA.
Scott B; BioInVision, Inc., Mayfield, OH, 44143, USA.
Roy D; BioInVision, Inc., Mayfield, OH, 44143, USA.
Haynes BF; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
Kwiek JJ; Department of Microbiology, Ohio State University, Columbus, OH, 43210, USA.
Haystead TAJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Oct 27; Vol. 12 (1), pp. 18091. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Lymphocyte Activation*
Arthritis, Rheumatoid*/drug therapy
Mice ; Animals ; Humans ; HSP90 Heat-Shock Proteins/metabolism ; T-Lymphocytes ; Disease Models, Animal

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Skocz do pozycji: 9.

Tytuł:: An updated view into the cell cycle kinetics of human T lymphocytes and the impact of irradiation.
Autorzy:: Duthoo E; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Vral A; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Baeyens A; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium. .; Cancer Research Institute Ghent (CRIG), Ghent, Belgium. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 May 10; Vol. 12 (1), pp. 7687. Date of Electronic Publication: 2022 May 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Lymphocyte Activation*
T-Lymphocytes*
Cell Cycle ; Humans ; Kinetics ; Lymphocytes/metabolism ; Phytohemagglutinins/metabolism ; Phytohemagglutinins/pharmacology

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Skocz do pozycji: 10.

Tytuł:: Clinical characteristics and treatment of elderly onset adult-onset Still's disease.
Autorzy:: Kishida D; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan. .
Ichikawa T; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan.
Takamatsu R; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan.
Nomura S; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan.
Matsuda M; Department of Rheumatology, Saku Central Hospital, Saku, Japan.
Ishii W; Division of Rheumatology, Department of Internal Medicine, Nagano Red Cross Hospital, Nagano, Japan.
Nagai T; Department of Rheumatology, Minaminagano Medical Center, Shinonoi General Hospital, Nagano, Japan.
Suzuki S; Department of Rheumatology, Minaminagano Medical Center, Shinonoi General Hospital, Nagano, Japan.
Ueno KI; Department of Rheumatology, Japanese Red Cross Society Suwa Hospital, Suwa, Japan.
Tachibana N; Department of Nephrology, Japanese Red Cross Society Suwa Hospital, Suwa, Japan.
Shimojima Y; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan.
Sekijima Y; Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Apr 26; Vol. 12 (1), pp. 6787. Date of Electronic Publication: 2022 Apr 26.
Typ publikacji:: Journal Article; Multicenter Study
MeSH Terms:: Cytomegalovirus Infections*/complications
Macrophage Activation Syndrome*/complications
Macrophage Activation Syndrome*/drug therapy
Still's Disease, Adult-Onset*/complications
Still's Disease, Adult-Onset*/drug therapy
Still's Disease, Adult-Onset*/epidemiology
Adult ; Aged ; Humans ; Immunosuppressive Agents/therapeutic use ; Retrospective Studies

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Skocz do pozycji: 11.

Tytuł:: Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes.
Autorzy:: Fischer K; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Bradlerova M; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Decker T; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria. .; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria. .
Supper V; Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Oct 30; Vol. 13 (1), pp. 18651. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: T-Lymphocytes*
Listeria monocytogenes*/metabolism
Humans ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; Butyrophilins/genetics ; Butyrophilins/metabolism ; Antigens ; Epithelial Cells/metabolism ; Lymphocyte Activation ; Antigens, CD/metabolism

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Skocz do pozycji: 12.

Tytuł:: A novel noble metal stent coating reduces in vitro platelet activation and acute in vivo thrombosis formation: a blinded study.
Autorzy:: Sandell M; Division of Micro and Nanosystems, KTH Royal Institute of Technology, Malvinas väg 10, 114 28, Stockholm, Sweden.; Department of Clinical Neuroscience, Karolinska Institute, Tomtebodavägen 18A, 171 77, Stockholm, Sweden.; MedTechLabs, Stockholm, Sweden.
Ericsson A; Bactiguard AB, Alfred Nobels allé 150, 146 48, Tullinge, Sweden.
Al-Saadi J; Department of Clinical Neuroscience, Karolinska Institute, Tomtebodavägen 18A, 171 77, Stockholm, Sweden.
Södervall B; Bactiguard AB, Alfred Nobels allé 150, 146 48, Tullinge, Sweden.
Södergren E; Bactiguard AB, Alfred Nobels allé 150, 146 48, Tullinge, Sweden.
Grass S; Bactiguard AB, Alfred Nobels allé 150, 146 48, Tullinge, Sweden.
Sanchez J; Bactiguard AB, Alfred Nobels allé 150, 146 48, Tullinge, Sweden.; Department of Clinical Sciences, Danderyd Hospital, 182 88, Stockholm, Sweden.
Holmin S; Department of Clinical Neuroscience, Karolinska Institute, Tomtebodavägen 18A, 171 77, Stockholm, Sweden. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Oct 11; Vol. 13 (1), pp. 17225. Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Coronary Artery Disease*/drug therapy
Drug-Eluting Stents*
Thrombosis*/drug therapy
Percutaneous Coronary Intervention*
Humans ; Animals ; Swine ; Platelet Aggregation Inhibitors/pharmacology ; Platelet Aggregation Inhibitors/therapeutic use ; Stents/adverse effects ; Platelet Activation ; Treatment Outcome ; Drug Therapy, Combination

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Skocz do pozycji: 13.

Tytuł:: The effect of circulating iron on barrier integrity of primary human endothelial cells.
Autorzy:: Madsen MC; Department of Physiology, Amsterdam UMC, De Boelelaan 1118, Amsterdam, 1081 HV, Netherlands. .; Department of Internal Medicine, Amsterdam UMC, Amsterdam, Netherlands. .; Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, Netherlands. .
Podieh F; Department of Physiology, Amsterdam UMC, De Boelelaan 1118, Amsterdam, 1081 HV, Netherlands.
Overboom MC; Department of Physiology, Amsterdam UMC, De Boelelaan 1118, Amsterdam, 1081 HV, Netherlands.
Thijs A; Department of Internal Medicine, Amsterdam UMC, Amsterdam, Netherlands.
den Heijer M; Department of Internal Medicine, Amsterdam UMC, Amsterdam, Netherlands.; Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, Netherlands.
Hordijk PL; Department of Physiology, Amsterdam UMC, De Boelelaan 1118, Amsterdam, 1081 HV, Netherlands.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Oct 06; Vol. 13 (1), pp. 16857. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:: Journal Article
MeSH Terms:: Endothelium, Vascular*/metabolism
Humans ; Reactive Oxygen Species/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Up-Regulation ; Transcriptional Activation ; Cells, Cultured

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Skocz do pozycji: 14.

Tytuł:: The C-terminal transactivation domain of MITF interacts promiscuously with co-activator CBP/p300.
Autorzy:: Brown AD; Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, B3H 4R2, Canada.
Lynch K; Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, B3H 4R2, Canada.
Langelaan DN; Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, B3H 4R2, Canada. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Sep 26; Vol. 13 (1), pp. 16094. Date of Electronic Publication: 2023 Sep 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CREB-Binding Protein*/genetics
Melanoma*/genetics
Humans ; Microphthalmia-Associated Transcription Factor/genetics ; Transcriptional Activation ; Oncogenes

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Skocz do pozycji: 15.

Tytuł:: Calcineurin-mediated dephosphorylation enhances the stability and transactivation of c-Myc.
Autorzy:: Masaki T; Department of Veterinary Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8511, Japan.
Habara M; Department of Veterinary Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8511, Japan.
Hanaki S; Department of Veterinary Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8511, Japan.
Sato Y; Department of Veterinary Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8511, Japan.
Tomiyasu H; Department of Veterinary Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8511, Japan.
Miki Y; Department of Veterinary Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8511, Japan.
Shimada M; Department of Veterinary Biochemistry, Joint Faculty of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8511, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 12; Vol. 13 (1), pp. 13116. Date of Electronic Publication: 2023 Aug 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Calcineurin*/genetics
Calcineurin*/metabolism
Transcription Factors*/metabolism
Humans ; Mice ; Animals ; Transcriptional Activation ; Gene Expression Regulation ; Protein Processing, Post-Translational

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Skocz do pozycji: 16.

Tytuł:: Optimization of methods for the accurate characterization of whole blood neutrophils.
Autorzy:: Connelly AN; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Huijbregts RPH; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Pal HC; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Kuznetsova V; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Davis MD; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Ong KL; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Fay CX; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Greene ME; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Overton ET; Center for AIDS Research, University of Alabama at Birmingham, Birmingham, AL, USA.; Division of Infectious Disease, University of Alabama at Birmingham, Birmingham, AL, USA.
Hel Z; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA. .; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA. .; Center for AIDS Research, University of Alabama at Birmingham, Birmingham, AL, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Mar 07; Vol. 12 (1), pp. 3667. Date of Electronic Publication: 2022 Mar 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Neutrophil Activation*
Neutrophils*/metabolism
Cells, Cultured ; Leukocytes ; Reproducibility of Results

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Tytuł:: Ionic mitigation of CD4 T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc.
Autorzy:: Krone A; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Fu Y; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Schreiber S; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Kotrba J; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Borde L; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Nötzold A; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Thurm C; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Negele J; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Franz T; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Stegemann-Koniszewski S; Experimental Pneumology, Department of Pneumology, University Hospital Magdeburg/Medical Faculty, Otto-von-Guericke-University, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Schreiber J; Experimental Pneumology, Department of Pneumology, University Hospital Magdeburg/Medical Faculty, Otto-von-Guericke-University, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Garbers C; Institute of Pathology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Shukla A; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Geffers R; Genome Analytics, Helmholtz-Center for Infection Research (HZI), Braunschweig, Germany.
Schraven B; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Reinhold D; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Dudeck A; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Reinhold A; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Müller AJ; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Intravital Microscopy of Infection and Immunity, Helmholtz-Center for Infection Research (HZI), Braunschweig, Germany.; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Kahlfuss S; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. .; Institute of Medical Microbiology and Hospital Hygiene, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. .; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany. .; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Feb 04; Vol. 12 (1), pp. 1943. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aspartic Acid/*analogs & derivatives
Asthma/*drug therapy
Central Nervous System/*drug effects
Encephalomyelitis, Autoimmune, Experimental/*drug therapy
Energy Metabolism/*drug effects
Immunomodulating Agents/*pharmacology
Lung/*drug effects
Lymphocyte Activation/*drug effects
Pneumonia/*drug therapy
Th1 Cells/*drug effects
Th2 Cells/*drug effects
Zinc Compounds/*pharmacology
Animals ; Aspartic Acid/pharmacology ; Asthma/genetics ; Asthma/immunology ; Asthma/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Proliferation/drug effects ; Cells, Cultured ; Central Nervous System/immunology ; Central Nervous System/metabolism ; Encephalomyelitis, Autoimmune, Experimental/genetics ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Encephalomyelitis, Autoimmune, Experimental/metabolism ; Energy Metabolism/genetics ; Gene Expression Regulation ; Lung/immunology ; Lung/metabolism ; Lymphocyte Activation/genetics ; Mice, Inbred C57BL ; Mice, Transgenic ; Pneumonia/genetics ; Pneumonia/immunology ; Pneumonia/metabolism ; Pyroglyphidae/immunology ; Signal Transduction ; Th1 Cells/immunology ; Th1 Cells/metabolism ; Th2 Cells/immunology ; Th2 Cells/metabolism ; Transcription, Genetic ; Mice

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Skocz do pozycji: 18.

Tytuł:: Severity of thermal burn injury is associated with systemic neutrophil activation.
Autorzy:: Laggner M; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, 1090, Vienna, Austria.
Lingitz MT; Division of General Anesthesia and Intensive Care Medicine, Department of Anesthesia, Critical Care and Pain Medicine, Medical University of Vienna, 1090, Vienna, Austria.
Copic D; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, 1090, Vienna, Austria.
Direder M; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, 1090, Vienna, Austria.
Klas K; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, 1090, Vienna, Austria.
Bormann D; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, 1090, Vienna, Austria.
Gugerell A; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, 1090, Vienna, Austria.
Moser B; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Radtke C; Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, 1090, Vienna, Austria.
Hacker S; Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, 1090, Vienna, Austria.; Department of Plastic, Reconstructive and Aesthetic Surgery, Landesklinikum Wiener Neustadt, 2700, Wiener Neustadt, Austria.
Mildner M; Department of Dermatology, Medical University of Vienna, 1090, Vienna, Austria.
Ankersmit HJ; Department of Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. .; Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, 1090, Vienna, Austria. .
Haider T; Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 31; Vol. 12 (1), pp. 1654. Date of Electronic Publication: 2022 Jan 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neutrophil Activation*
Burns/*immunology
Neutrophils/*immunology
Adult ; Aged ; Biomarkers/blood ; Burns/blood ; Burns/diagnosis ; Burns/mortality ; Case-Control Studies ; Citrullination ; Complement C3/metabolism ; Female ; Histones/blood ; Humans ; Leukocyte Count ; Leukocyte Elastase/blood ; Male ; Middle Aged ; Neutrophils/metabolism ; Peroxidase/blood ; Predictive Value of Tests ; Prognosis ; Protein Processing, Post-Translational ; Severity of Illness Index ; Time Factors ; Young Adult

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Skocz do pozycji: 19.

Tytuł:: FOXO1 forkhead domain mutants in B-cell lymphoma lack transcriptional activity.
Autorzy:: Sablon A; Experimental Medicine Unit, De Duve Institute, Université Catholique de Louvain, Avenue Hippocrate 75, B1.74.05, 1200, Brussels, Belgium.
Bollaert E; Experimental Medicine Unit, De Duve Institute, Université Catholique de Louvain, Avenue Hippocrate 75, B1.74.05, 1200, Brussels, Belgium.
Pirson C; Experimental Medicine Unit, De Duve Institute, Université Catholique de Louvain, Avenue Hippocrate 75, B1.74.05, 1200, Brussels, Belgium.
Velghe AI; Experimental Medicine Unit, De Duve Institute, Université Catholique de Louvain, Avenue Hippocrate 75, B1.74.05, 1200, Brussels, Belgium.
Demoulin JB; Experimental Medicine Unit, De Duve Institute, Université Catholique de Louvain, Avenue Hippocrate 75, B1.74.05, 1200, Brussels, Belgium. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 25; Vol. 12 (1), pp. 1309. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Loss of Function Mutation*
Transcriptional Activation*
Forkhead Box Protein O1/*genetics
Forkhead Box Protein O1/*metabolism
Lymphoma, B-Cell/*genetics
Lymphoma, B-Cell/*metabolism
Protein Domains/*genetics
Signal Transduction/*genetics
Amino Acids/metabolism ; DNA/metabolism ; Forkhead Box Protein O1/chemistry ; HEK293 Cells ; Humans ; Phosphorylation/genetics ; Point Mutation ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Interaction Maps/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Transfection

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Tytuł:: Pax5 mediates the transcriptional activation of the CD81 gene.
Autorzy:: Hosokawa K; Department of Cell Biology, Kyoto Pharmaceutical University, Misasagi-Shichonocho 1, Yamashinaku, Kyoto-shi, Kyoto, 607-8412, Japan.
Ishimaru H; Department of Cell Biology, Kyoto Pharmaceutical University, Misasagi-Shichonocho 1, Yamashinaku, Kyoto-shi, Kyoto, 607-8412, Japan.
Watanabe T; Department of Cell Biology, Kyoto Pharmaceutical University, Misasagi-Shichonocho 1, Yamashinaku, Kyoto-shi, Kyoto, 607-8412, Japan.; Department of Virology, Graduate School of Medicine, University of the Ryukyus, Okinawa, 903-0215, Japan.
Fujimuro M; Department of Cell Biology, Kyoto Pharmaceutical University, Misasagi-Shichonocho 1, Yamashinaku, Kyoto-shi, Kyoto, 607-8412, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Nov 25; Vol. 11 (1), pp. 22919. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Promoter Regions, Genetic*
Transcriptional Activation*
Neoplasms/*metabolism
PAX5 Transcription Factor/*metabolism
Tetraspanin 28/*metabolism
A549 Cells ; Binding Sites ; Cell Movement ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; HeLa Cells ; Humans ; MCF-7 Cells ; Neoplasm Invasiveness ; Neoplasms/genetics ; Neoplasms/pathology ; PAX5 Transcription Factor/genetics ; Protein Binding ; Tetraspanin 28/genetics

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