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Wyszukujesz frazę ""adaptive immunity"" wg kryterium: Temat


Tytuł :
The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity.
Autorzy :
Bolouri H; Center for Systems Immunology, Benaroya Research Institute (BRI) at Virginia Mason, Seattle, Washington, USA.; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Speake C; Center for Interventional Immunology.
Skibinski D; Center for Interventional Immunology.
Long SA; Center for Translational Immunology, and.
Hocking AM; Center for Translational Immunology, and.
Campbell DJ; Center for Fundamental Immunology, Benaroya Research Institute (BRI) at Virginia Mason, Seattle, Washington, USA.; Department of Immunology, University of Washington School of Medicine, Seattle, Washington, USA.
Hamerman JA; Center for Fundamental Immunology, Benaroya Research Institute (BRI) at Virginia Mason, Seattle, Washington, USA.; Department of Immunology, University of Washington School of Medicine, Seattle, Washington, USA.
Malhotra U; Department of Infectious Disease, Virginia Mason Medical Center, Seattle, Washington, USA.; Department of Medicine, Section of Infectious Diseases, University of Washington, Seattle, Washington, USA.
Buckner JH; Center for Translational Immunology, and.; Department of Immunology, University of Washington School of Medicine, Seattle, Washington, USA.
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Corporate Authors :
Benaroya Research Institute COVID-19 Research Team
Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 Feb 01; Vol. 131 (3).
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Video-Audio Media
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
Severity of Illness Index*
COVID-19/*immunology
SARS-CoV-2/*immunology
Adult ; Aged ; Aged, 80 and over ; COVID-19/drug therapy ; Female ; Flow Cytometry ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
What chances do children have against COVID-19? Is the answer hidden within the thymus?
Autorzy :
Güneş H; Department of Pediatrics, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
Dinçer S; Department of Pediatrics, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
Acıpayam C; Department of Pediatric Hematology and Oncology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
Yurttutan S; Department of Pediatrics Division of Neonatology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Avsar Campus, 46100, Kahramanmaras, Turkey. .
Özkars MY; Department of Pediatric Allergy and Immunology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
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Źródło :
European journal of pediatrics [Eur J Pediatr] 2021 Mar; Vol. 180 (3), pp. 983-986. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptive Immunity*
COVID-19/*immunology
T-Lymphocytes/*immunology
Thymus Gland/*immunology
COVID-19/diagnosis ; Child ; Humans ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Kinase inhibitors developed for treatment of hematologic malignancies: implications for immune modulation in COVID-19.
Autorzy :
Jacobs CF; Department of Experimental Immunology and.; Department of Hematology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection & Immunity, Amsterdam, The Netherlands; and.
Eldering E; Department of Experimental Immunology and.; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection & Immunity, Amsterdam, The Netherlands; and.; Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
Kater AP; Department of Hematology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection & Immunity, Amsterdam, The Netherlands; and.; Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
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Źródło :
Blood advances [Blood Adv] 2021 Feb 09; Vol. 5 (3), pp. 913-925.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
COVID-19/*pathology
Hematologic Neoplasms/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Agammaglobulinaemia Tyrosine Kinase/antagonists & inhibitors ; Agammaglobulinaemia Tyrosine Kinase/metabolism ; COVID-19/complications ; COVID-19/immunology ; COVID-19/virology ; Cytokines/metabolism ; Fusion Proteins, bcr-abl/antagonists & inhibitors ; Fusion Proteins, bcr-abl/metabolism ; Hematologic Neoplasms/complications ; Hematologic Neoplasms/pathology ; Humans ; SARS-CoV-2/isolation & purification
Czasopismo naukowe
Tytuł :
Association between markers of immune response at hospital admission and COVID-19 disease severity and mortality: A meta-analysis and meta-regression.
Autorzy :
Khinda J; University of British Columbia, Vancouver, Canada.
Janjua NZ; University of British Columbia, Vancouver, Canada.; BC Centre for Disease Control, Vancouver, Canada.; Centre for Health Evaluation and Outcome Sciences (CHÉOS), Vancouver, Canada.
Cheng S; Library, BC Cancer, Vancouver, Canada.
van den Heuvel ER; Department of Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, Netherlands.; Department of Preventive Medicine and Epidemiology, School of Medicine, Boston University, Boston, Massachusetts.
Bhatti P; Cancer Control Research, BC Cancer Research Centre, Vancouver, Canada.
Darvishian M; Cancer Control Research, BC Cancer Research Centre, Vancouver, Canada.
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Źródło :
Journal of medical virology [J Med Virol] 2021 Feb; Vol. 93 (2), pp. 1078-1098. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Adaptive Immunity*
Inflammation*
COVID-19/*immunology
COVID-19/*mortality
Hospitalization/*statistics & numerical data
Biomarkers/blood ; C-Reactive Protein/analysis ; COVID-19/physiopathology ; Female ; Fibrin Fibrinogen Degradation Products/analysis ; Humans ; Lymphocytes ; Male ; Neutrophils ; Regression Analysis ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
The tumor-promoting effects of the adaptive immune system: a cause of hyperprogressive disease in cancer?
Autorzy :
Marcucci F; Department of Pharmacological and Biomolecular Sciences, University of Milan, via Trentacoste 2, Milan, Italy. .
Rumio C; Department of Pharmacological and Biomolecular Sciences, University of Milan, via Trentacoste 2, Milan, Italy.
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Feb; Vol. 78 (3), pp. 853-865. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adaptive Immunity*
Neoplasms/*pathology
Antibodies/immunology ; Antibodies/metabolism ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; B7-H1 Antigen/immunology ; B7-H1 Antigen/metabolism ; Cytokines/metabolism ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Neoplasms/drug therapy ; Neoplasms/immunology ; Programmed Cell Death 1 Receptor/immunology ; Programmed Cell Death 1 Receptor/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Postinfectious Epigenetic Immune Modifications - A Double-Edged Sword.
Autorzy :
DiNardo AR; From the Global Tuberculosis Program, William T. Shearer Center for Human Immunobiology, Texas Children's Hospital (A.R.D.), the Immigrant and Global Health Program, Department of Pediatrics (A.R.D.), and the Departments of Medicine and Molecular Virology and Microbiology (D.M.M.), Baylor College of Medicine, and the Medical Care Line, Infectious Disease Section, Michael E. DeBakey Veterans Affairs Medical Center (D.M.M.) - all in Houston; the Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands (M.G.N.); and the Department of Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany (M.G.N.).
Netea MG; From the Global Tuberculosis Program, William T. Shearer Center for Human Immunobiology, Texas Children's Hospital (A.R.D.), the Immigrant and Global Health Program, Department of Pediatrics (A.R.D.), and the Departments of Medicine and Molecular Virology and Microbiology (D.M.M.), Baylor College of Medicine, and the Medical Care Line, Infectious Disease Section, Michael E. DeBakey Veterans Affairs Medical Center (D.M.M.) - all in Houston; the Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands (M.G.N.); and the Department of Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany (M.G.N.).
Musher DM; From the Global Tuberculosis Program, William T. Shearer Center for Human Immunobiology, Texas Children's Hospital (A.R.D.), the Immigrant and Global Health Program, Department of Pediatrics (A.R.D.), and the Departments of Medicine and Molecular Virology and Microbiology (D.M.M.), Baylor College of Medicine, and the Medical Care Line, Infectious Disease Section, Michael E. DeBakey Veterans Affairs Medical Center (D.M.M.) - all in Houston; the Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands (M.G.N.); and the Department of Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany (M.G.N.).
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Źródło :
The New England journal of medicine [N Engl J Med] 2021 Jan 21; Vol. 384 (3), pp. 261-270.
Typ publikacji :
Historical Article; Journal Article; Review
MeSH Terms :
Epigenesis, Genetic*
Adaptive Immunity/*genetics
Immunogenicity, Vaccine/*genetics
Infections/*genetics
Adaptive Immunity/immunology ; Allergy and Immunology/history ; Animals ; Disease Models, Animal ; History, 19th Century ; History, 20th Century ; Humans ; Immunologic Memory/genetics ; Infections/immunology
Czasopismo naukowe
Tytuł :
Prolonged adaptive immune activation in COVID-19: implications for maintenance of long-term immunity?
Autorzy :
Mudd PA; Department of Emergency Medicine.
Remy KE; Division of Critical Care Medicine, Department of Pediatrics; and.; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 Jan 04; Vol. 131 (1).
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural
MeSH Terms :
Adaptive Immunity*
B-Lymphocytes/*immunology
COVID-19/*immunology
SARS-CoV-2/*immunology
T-Lymphocytes/*immunology
B-Lymphocytes/pathology ; COVID-19/pathology ; Female ; Humans ; Male ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł :
Protective immunity against COVID-19: Unravelling the evidences for humoral vs. cellular components.
Autorzy :
Priyanka; Independent Researcher, 07, Type IV Quarter, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University (I), Selesih, Aizawl, 796015, Mizoram, India.
Choudhary OP; Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University (I), Selesih, Aizawl, 796015, Mizoram, India. Electronic address: .
Singh I; Medical Superintendent, Community Health Centre, Deoband, Saharanpur, 247554, Uttar Pradesh, India.
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Źródło :
Travel medicine and infectious disease [Travel Med Infect Dis] 2021 Jan-Feb; Vol. 39, pp. 101911. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Letter
MeSH Terms :
Adaptive Immunity*
COVID-19/*immunology
COVID-19/prevention & control ; COVID-19 Vaccines/immunology ; Humans ; Reinfection/immunology ; SARS-CoV-2/immunology
Opinia redakcyjna
Tytuł :
Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones.
Autorzy :
Viveiros A; Department of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.
Rasmuson J; Department of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Vu J; Department of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Mulvagh SL; Division of Cardiology, Dalhousie University, Halifax, Canada.; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Yip CYY; Heart and Stroke Foundation of Canada, Toronto, Canada.
Norris CM; Division of Cardiology, Dalhousie University, Halifax, Canada.; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.; Faculty of Nursing, University of Alberta, Edmonton, Canada.
Oudit GY; Division of Cardiology, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2021 Jan 01; Vol. 320 (1), pp. H296-H304. Date of Electronic Publication: 2020 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adaptive Immunity/*immunology
Androgens/*immunology
Angiotensin-Converting Enzyme 2/*genetics
COVID-19/*immunology
Estrogens/*immunology
Immunity, Innate/*immunology
Receptors, Coronavirus/*genetics
ADAM17 Protein/metabolism ; Adaptive Immunity/genetics ; Androgens/metabolism ; Angiotensin-Converting Enzyme 2/metabolism ; COVID-19/genetics ; COVID-19/metabolism ; COVID-19/mortality ; Cardiovascular Diseases/genetics ; Cardiovascular Diseases/immunology ; Estrogens/metabolism ; Female ; Genes, X-Linked/genetics ; Genes, X-Linked/immunology ; Humans ; Immunity, Innate/genetics ; Male ; Promoter Regions, Genetic ; Receptors, Coronavirus/metabolism ; Renin-Angiotensin System/genetics ; Renin-Angiotensin System/immunology ; Response Elements/genetics ; SARS-CoV-2/metabolism ; Severity of Illness Index ; Sex Characteristics ; Sex Factors ; X Chromosome Inactivation
Czasopismo naukowe
Tytuł :
What are the immune responses during the growth of Ehrlich's tumor in ascitic and solid form?
Autorzy :
Feitosa IB; Instituto de Ciências Biológicas, Programa de Pós-graduação em Imunologia Básica e Aplicada, PPGIBA, Universidade Federal do Amazonas (UFAM), Manaus, Amazonas State, Brazil. Electronic address: .
Mori B; Instituto de Ciências Biológicas, Programa de Pós-graduação em Imunologia Básica e Aplicada, PPGIBA, Universidade Federal do Amazonas (UFAM), Manaus, Amazonas State, Brazil.
Teles CBG; Plataforma Técnica de Bioensaio de Malária e Leishmaniose, Fundação Oswaldo Cruz, Fiocruz, Rondônia/Centro Universitário São Lucas, Departamento de Medicina/Instituto Nacional de Epidemiologia na Amazônia Ocidental, Porto Velho, Rondônia State, Brazil.
Costa AGD; Instituto de Ciências Biológicas, Programa de Pós-graduação em Imunologia Básica e Aplicada, PPGIBA, Universidade Federal do Amazonas (UFAM), Manaus, Amazonas State, Brazil; Diretoria de Ensino e Pesquisa, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, Amazonas State, Brazil.
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118578. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Adaptive Immunity/*physiology
Carcinoma, Ehrlich Tumor/*immunology
Carcinoma, Ehrlich Tumor/*pathology
Immunity, Innate/*physiology
Adaptive Immunity/drug effects ; Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Carcinoma, Ehrlich Tumor/drug therapy ; Humans ; Immunity, Cellular/drug effects ; Immunity, Cellular/physiology ; Immunity, Innate/drug effects ; Mice ; Tumor Burden/drug effects ; Tumor Burden/physiology
Czasopismo naukowe
Tytuł :
Atherosclerosis and Inflammatory Bowel Disease-Shared Pathogenesis and Implications for Treatment.
Autorzy :
Kamperidis N; 3749St Mark's Hospital, Harrow, London, United Kingdom.;   Nikolaos Kamperidis and Vasileios Kamperidis are sharing first authorship.
Kamperidis V; 1st Cardiology Department, 37788AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.;   Nikolaos Kamperidis and Vasileios Kamperidis are sharing first authorship.
Zegkos T; 1st Cardiology Department, 37788AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Kostourou I; 3749St Mark's Hospital, Harrow, London, United Kingdom.
Nikolaidou O; Radiology Department, Pananikolaou General Hospital, Thessaloniki, Greece.
Arebi N; 3749St Mark's Hospital, Harrow, London, United Kingdom.
Karvounis H; 1st Cardiology Department, 37788AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Źródło :
Angiology [Angiology] 2021 Apr; Vol. 72 (4), pp. 303-314. Date of Electronic Publication: 2020 Dec 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
Life Style*
Polymorphism, Single Nucleotide*
Atherosclerosis/*etiology
Inflammatory Bowel Diseases/*etiology
Animals ; Atherosclerosis/genetics ; Atherosclerosis/immunology ; Atherosclerosis/therapy ; Gastrointestinal Microbiome ; Genetic Predisposition to Disease ; Humans ; Inflammatory Bowel Diseases/genetics ; Inflammatory Bowel Diseases/immunology ; Inflammatory Bowel Diseases/therapy ; Phenotype ; Polymorphism, Genetic ; Risk Assessment ; Risk Factors ; Vitamin D/immunology
Czasopismo naukowe
Tytuł :
Systemic innate and adaptive immune responses to SARS-CoV-2 as it relates to other coronaviruses.
Autorzy :
O'Connell P; Department of Microbiology and Molecular Genetics, College of Osteopathic Medicine, Michigan State University , East Lansing, MI, USA.
Aldhamen YA; Department of Microbiology and Molecular Genetics, College of Osteopathic Medicine, Michigan State University , East Lansing, MI, USA.
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Źródło :
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2020 Dec 01; Vol. 16 (12), pp. 2980-2991. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adaptive Immunity/*immunology
COVID-19/*therapy
Coronavirus Infections/*immunology
Immunity, Innate/*immunology
Immunotherapy/*methods
SARS-CoV-2/*immunology
Severe Acute Respiratory Syndrome/*immunology
Adaptive Immunity/drug effects ; Animals ; COVID-19/epidemiology ; COVID-19/immunology ; Coronavirus/drug effects ; Coronavirus/immunology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Humans ; Immunity, Innate/drug effects ; Immunotherapy/trends ; SARS-CoV-2/drug effects ; Severe Acute Respiratory Syndrome/epidemiology ; Severe Acute Respiratory Syndrome/therapy
Czasopismo naukowe
Tytuł :
Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity.
Autorzy :
Rydyznski Moderbacher C; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Ramirez SI; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
Dan JM; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
Grifoni A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Hastie KM; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Weiskopf D; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Belanger S; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Abbott RK; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Kim C; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Choi J; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Kato Y; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Crotty EG; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Kim C; Flow Cytometry Core Facility, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Rawlings SA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
Mateus J; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Tse LPV; Department of Epidemiology, UNC Chapel Hill School of Public Health, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Frazier A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Baric R; Department of Epidemiology, UNC Chapel Hill School of Public Health, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Peters B; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Greenbaum J; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Ollmann Saphire E; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
Smith DM; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
Sette A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA. Electronic address: .
Crotty S; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA. Electronic address: .
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Źródło :
Cell [Cell] 2020 Nov 12; Vol. 183 (4), pp. 996-1012.e19. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptive Immunity*
Antigens, Viral/*immunology
Coronavirus Infections/*pathology
Pneumonia, Viral/*pathology
Acute Disease ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; Betacoronavirus/immunology ; Betacoronavirus/isolation & purification ; Betacoronavirus/metabolism ; CD4-Positive T-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Cytokines/blood ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Severity of Illness Index ; Young Adult
Czasopismo naukowe
Tytuł :
IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria.
Autorzy :
Ngo VL; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Abo H; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Kuczma M; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Szurek E; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Moore N; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Medina-Contreras O; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Nusrat A; Department of Pathology, University of Michigan, Ann Arbor, MI 48109.
Merlin D; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Gewirtz AT; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Ignatowicz L; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Denning TL; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 03; Vol. 117 (44), pp. 27540-27548. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
Citrobacter rodentium/*immunology
Enterobacteriaceae Infections/*immunology
Receptors, Interleukin-1/*metabolism
Animals ; Citrobacter rodentium/pathogenicity ; Disease Models, Animal ; Enterobacteriaceae Infections/microbiology ; Interleukin-1/metabolism ; Intestinal Mucosa/immunology ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/microbiology ; Mice ; Mice, Knockout ; Receptors, Interleukin-1/genetics ; Signal Transduction/genetics ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
COVID-19: Loss of bridging between innate and adaptive immunity?
Autorzy :
Rao VUS; Department of Head and Neck Oncology, HCG Cancer Hospital, Bengaluru, Karnataka, India. Electronic address: .
Arakeri G; Department of Head and Neck Oncology, HCG Cancer Hospital, Bengaluru, Karnataka, India.
Subash A; Department of Head and Neck Oncology, HCG Cancer Hospital, Bengaluru, Karnataka, India.
Rao J; iCREST, International Stemcell Services Ltd., HealthCare Global Enterprises Ltd., Bengaluru, Karnataka, India.
Jadhav S; Department of Hematology, Immunology and Medical Oncology, HCG Cancer Hospital, Bengaluru, Karnataka, India.
Suhail Sayeed M; Department of Translational Medicine and Therapeutics, HCG Cancer Hospital, Bengaluru, Karnataka, India.
Rao G; iCREST, International Stemcell Services Ltd., HealthCare Global Enterprises Ltd., Bengaluru, Karnataka, India.
Brennan PA; Department of Oral & Maxillofacial Surgery, Queen Alexandra Hospital, Cosham, Portsmouth, UK.
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Źródło :
Medical hypotheses [Med Hypotheses] 2020 Nov; Vol. 144, pp. 109861. Date of Electronic Publication: 2020 May 23.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
COVID-19/*immunology
COVID-19/*therapy
Cytokines/immunology ; Humans ; Immunization, Passive ; Interferons/immunology ; Interferons/metabolism ; Risk ; Th1 Cells/immunology ; Treatment Outcome
SCR Protocol :
COVID-19 serotherapy
Czasopismo naukowe
Tytuł :
Naturally activated adaptive immunity in COVID-19 patients.
Autorzy :
Yang X; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Dai T; Department of Clinical Laboratory, The 8th hospital of Xi'an, Xi'an, Shaanxi, China.
Zhou X; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Qian H; Department of Clinical Laboratory, The 8th hospital of Xi'an, Xi'an, Shaanxi, China.
Guo R; Department of Clinical Laboratory, The 8th hospital of Xi'an, Xi'an, Shaanxi, China.
Lei L; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Zhang X; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Zhang D; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Shi L; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Cheng Y; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Hu J; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Guo Y; Department of Clinical Laboratory, The 8th hospital of Xi'an, Xi'an, Shaanxi, China.
Zhang B; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, Shaanxi, China.; Institute of infection and immunity, Translational Medicine Institute, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.; Basic and Translational Research Laboratory of Immune Related Diseases, Xi'an, Shaanxi, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Nov; Vol. 24 (21), pp. 12457-12463. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptive Immunity*
COVID-19/*immunology
Adult ; Antigens, CD/metabolism ; B-Lymphocytes/virology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/virology ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/virology ; COVID-19/blood ; Female ; Humans ; Immunophenotyping ; Male ; Programmed Cell Death 1 Receptor/metabolism ; Receptors, CXCR5/metabolism
Czasopismo naukowe
Tytuł :
SARS-CoV-2 infection induces mixed M1/M2 phenotype in circulating monocytes and alterations in both dendritic cell and monocyte subsets.
Autorzy :
Matic S; Department of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Popovic S; Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Djurdjevic P; Department of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Clinic for Haematology, Clinical Centre Kragujevac, Kragujevac, Serbia.
Todorovic D; Department of Genetics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Djordjevic N; Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Mijailovic Z; Department of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Department of Infectious Diseases, Clinical Centre Kragujevac, Kragujevac, Serbia.
Sazdanovic P; Department of Anatomy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Gynecology and Obstetrics Clinic, Clinical Centre Kragujevac, Kragujevac, Serbia.
Milovanovic D; Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Department of Clinical Pharmacology, Clinical Centre Kragujevac, Kragujevac, Serbia.
Ruzic Zecevic D; Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Department of Clinical Pharmacology, Clinical Centre Kragujevac, Kragujevac, Serbia.
Petrovic M; Department of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Clinic for Pulmonology, Clinical Centre Kragujevac, Kragujevac, Serbia.
Sazdanovic M; Department of Histology and Embryology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Zornic N; Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Corona Centre, Clinical Centre Kragujevac, Kragujevac, Serbia.
Vukicevic V; Corona Centre, Clinical Centre Kragujevac, Kragujevac, Serbia.
Petrovic I; Department of Microbiology, Clinical Centre Kragujevac, Kragujevac, Serbia.
Matic S; Department of Microbiology, Clinical Centre Kragujevac, Kragujevac, Serbia.
Karic Vukicevic M; Department of Rheumatology, Allergology and Clinical Immunology, Clinical Centre Kragujevac, Kragujevac, Serbia.
Baskic D; Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Public Health Institute, Kragujevac, Kragujevac, Serbia.
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Źródło :
PloS one [PLoS One] 2020 Dec 31; Vol. 15 (12), pp. e0241097. Date of Electronic Publication: 2020 Dec 31 (Print Publication: 2020).
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
COVID-19/*immunology
Dendritic Cells/*immunology
Monocytes/*immunology
SARS-CoV-2/*immunology
Adult ; Aged ; Aged, 80 and over ; Antigens, Differentiation/immunology ; COVID-19/pathology ; Dendritic Cells/pathology ; Female ; Flow Cytometry ; HLA-DR Antigens/immunology ; Humans ; Killer Cells, Natural/immunology ; Killer Cells, Natural/pathology ; Male ; Middle Aged ; Monocytes/pathology
Czasopismo naukowe
Tytuł :
Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases.
Autorzy :
Carsetti R; B Cell Pathophysiology Unit, Immunology Research Area, Bambino Gesù Children's Hospital Istituto di Ricovero e Cura a Carattere Scientifico (IRCSS), Rome, Italy.; Diagnostic Immunology Unit, Department of Laboratories, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Zaffina S; Occupational Medicine/Health Technology Assessment and Safety Research Unit, Clinical-Technological Innovations Research Area, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy.; Health Directorate, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.
Piano Mortari E; B Cell Pathophysiology Unit, Immunology Research Area, Bambino Gesù Children's Hospital Istituto di Ricovero e Cura a Carattere Scientifico (IRCSS), Rome, Italy.
Terreri S; B Cell Pathophysiology Unit, Immunology Research Area, Bambino Gesù Children's Hospital Istituto di Ricovero e Cura a Carattere Scientifico (IRCSS), Rome, Italy.
Corrente F; Diagnostic Immunology Unit, Department of Laboratories, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Capponi C; Diagnostic Immunology Unit, Department of Laboratories, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Palomba P; Diagnostic Immunology Unit, Department of Laboratories, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Mirabella M; Diagnostic Immunology Unit, Department of Laboratories, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Cascioli S; Research Laboratories, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Palange P; Department of Public Health and Infectious Diseases Pulmonary Division, Policlinico Umberto I Hospital, Rome, Italy.
Cuccaro I; Department of Public Health and Infectious Diseases Pulmonary Division, Policlinico Umberto I Hospital, Rome, Italy.
Milito C; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Zumla A; Center for Clinical Microbiology, Division of Infection and Immunity, University College London, London, United Kingdom.; NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, United Kingdom.
Maeurer M; Immunotherapy Programme, Champalimaud Foundation, Lisbon, Portugal.; Med Clinic, University of Mainz, Mainz, Germany.
Camisa V; Occupational Medicine/Health Technology Assessment and Safety Research Unit, Clinical-Technological Innovations Research Area, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy.; Health Directorate, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.
Vinci MR; Occupational Medicine/Health Technology Assessment and Safety Research Unit, Clinical-Technological Innovations Research Area, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy.; Health Directorate, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.
Santoro A; Occupational Medicine/Health Technology Assessment and Safety Research Unit, Clinical-Technological Innovations Research Area, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy.; Health Directorate, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.
Cimini E; Cellular Immunology Laboratory, INMI L Spallanzani, IRCCS, Rome, Italy.
Marchioni L; Clinical Department, INMI L Spallanzani, IRCCS, Rome, Italy.
Nicastri E; Clinical Department, INMI L Spallanzani, IRCCS, Rome, Italy.
Palmieri F; Clinical Department, INMI L Spallanzani, IRCCS, Rome, Italy.
Agrati C; Cellular Immunology Laboratory, INMI L Spallanzani, IRCCS, Rome, Italy.
Ippolito G; Scientific Direction, INMI L Spallanzani, IRCCS, Rome, Italy.
Porzio O; Medical Laboratory Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.
Concato C; Virology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Onetti Muda A; Department of Laboratories, Bambino Gesù Children's Hospital, Rome, Italy.
Raponi M; Health Directorate, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.
Quintarelli C; Department of Hematology/Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.; Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Quinti I; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Locatelli F; Department of Hematology/Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.; Department of Pediatrics, Sapienza, University of Rome, Rome, Italy.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Dec 16; Vol. 11, pp. 610300. Date of Electronic Publication: 2020 Dec 16 (Print Publication: 2020).
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
Antibodies, Viral/*immunology
COVID-19/*immunology
Immunoglobulin A/*immunology
Immunoglobulin M/*immunology
Killer Cells, Natural/*immunology
SARS-CoV-2/*immunology
Adult ; COVID-19/pathology ; Female ; Humans ; Killer Cells, Natural/pathology ; Male ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Estriol in regulation of cell-mediated immune reactions in multiple sclerosis.
Autorzy :
Nekrasova I; Perm Federal Research Center, Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Goleva str., 13, 614081 Perm, Russia. Electronic address: .
Shirshev S; Perm Federal Research Center, Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Goleva str., 13, 614081 Perm, Russia.
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Źródło :
Journal of neuroimmunology [J Neuroimmunol] 2020 Dec 15; Vol. 349, pp. 577421. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptive Immunity/*immunology
Estriol/*pharmacology
Immunity, Cellular/*immunology
Immunity, Innate/*immunology
Multiple Sclerosis/*immunology
Adaptive Immunity/drug effects ; Adult ; Cells, Cultured ; Dose-Response Relationship, Drug ; Female ; Humans ; Immunity, Cellular/drug effects ; Immunity, Innate/drug effects ; Male ; Multiple Sclerosis/blood
Czasopismo naukowe

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