Temat: "adenosine" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Use of Remdesivir in children with COVID-19: report of an Italian multicenter study.
Autorzy:: Romani L; Infectious Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. .
Roversi M; PhD Course 'Immunology, Molecular Medicine and Applied Biotechnology', University of Rome Tor Vergata, Rome, Italy.
Bernardi S; Infectious Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Venturini E; Infectious Diseases Unit, Meyer Children's University Hospital, Florence, Italy.
Garazzino S; Pediatric Infectious Diseases Unit, Regina Margherita Children's Hospital, University of Turin, Turin, Italy.
Donà D; Division of Pediatric Infectious Diseases, Department for Woman and Child Health, University of Padua, Padua, Italy.
Krzysztofiak A; Infectious Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Montagnani C; Infectious Diseases Unit, Meyer Children's University Hospital, Florence, Italy.
Funiciello E; Pediatric Infectious Diseases Unit, Regina Margherita Children's Hospital, University of Turin, Turin, Italy.
Calò Carducci FI; Infectious Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Marabotto C; Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Castagnola E; Hematology and Oncology, Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Salvini F; Pediatrics Division, Azienda Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Lancella L; Infectious Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Lo Vecchio A; Department of Translational Medical Sciences, Federico II University, Naples, Italy.
Galli L; Infectious Diseases Unit, Meyer Children's University Hospital, Florence, Italy.
Castelli Gattinara G; Institute of Child Health, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.; Pokaż więcej
Corporate Authors:: Italian Society of Pediatric Infectious Diseases (SITIP)
Źródło:: Italian journal of pediatrics [Ital J Pediatr] 2024 Feb 27; Vol. 50 (1), pp. 32. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Multicenter Study; Journal Article
MeSH Terms:: Adenosine Monophosphate*/analogs & derivatives
Alanine*/analogs & derivatives
COVID-19*
Child ; Humans ; Antiviral Agents/therapeutic use ; COVID-19 Drug Treatment ; Italy/epidemiology ; SARS-CoV-2

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Skocz do pozycji: 2.

Tytuł:: Comparable outcomes of outpatient remdesivir and sotrovimab among high-risk patients with mild to moderate COVID-19 during the omicron BA.1 surge.
Autorzy:: Chesdachai S; Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA. .
Rivera CG; Department of Pharmacy, Mayo Clinic, Rochester, MN, USA.
Cole KC; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Teaford HR; Department of Pharmacy, Mayo Clinic, Rochester, MN, USA.
Gonzalez Suarez ML; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Larsen JJ; Department of Nursing, Mayo Clinic, Rochester, MN, USA.
Ganesh R; Department of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Tulledge-Scheitel S; Department of Community Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Razonable RR; Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 05; Vol. 14 (1), pp. 5430. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:: Journal Article
MeSH Terms:: Outpatients*
COVID-19*
Antibodies, Neutralizing*
Antibodies, Monoclonal, Humanized*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Humans ; COVID-19 Vaccines ; SARS-CoV-2 ; COVID-19 Drug Treatment

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Skocz do pozycji: 3.

Tytuł:: Risk factors for hyperglycemia in COVID-19 patients treated with remdesivir.
Autorzy:: Kim W; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.; Department of Pharmacy, Kangwon National University, Chuncheon, Korea.
Lee GW; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.; Department of Pharmacy, Bestian Hospital, Cheongju-si, Korea.
Rhee N; Medical Department, Bestian Hospital, Cheongju-si, Korea.
Min KH; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.
Kim JH; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.
Gil JY; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.
Kim SY; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.; National Institute of Food and Drug Safety Evaluation, Cheongju-si, Korea.
Han JM; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.
Lee KE; College of Pharmacy, Chungbuk National University, Cheongju-si, Korea.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13684. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19*
Hyperglycemia*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Humans ; COVID-19 Drug Treatment ; Risk Factors

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Skocz do pozycji: 4.

Tytuł:: Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity.
Autorzy:: Huang S; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Jia A; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Song W; Institute of Biochemistry, University of Cologne, 50674 Cologne, Germany.; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.
Hessler G; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.
Meng Y; School of Pharmaceutical Sciences, Zhengzhou University, 450001 Zhengzhou, China.
Sun Y; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Xu L; National Protein Science Facility, Tsinghua University, 100084 Beijing, China.
Laessle H; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.
Jirschitzka J; Institute of Biochemistry, University of Cologne, 50674 Cologne, Germany.; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.
Ma S; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Xiao Y; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Yu D; Institute of Biochemistry, University of Cologne, 50674 Cologne, Germany.; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.
Hou J; School of Pharmaceutical Sciences, Zhengzhou University, 450001 Zhengzhou, China.
Liu R; School of Pharmaceutical Sciences, Zhengzhou University, 450001 Zhengzhou, China.
Sun H; Institute of Biochemistry, University of Cologne, 50674 Cologne, Germany.; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.
Liu X; National Protein Science Facility, Tsinghua University, 100084 Beijing, China.
Han Z; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Chang J; School of Pharmaceutical Sciences, Zhengzhou University, 450001 Zhengzhou, China.; Henan Key Laboratory of Organic Functional Molecules and Drug Innovation, Henan Normal University, 453007 Xinxiang, China.
Parker JE; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.
Chai J; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.; Institute of Biochemistry, University of Cologne, 50674 Cologne, Germany.; Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, 50829 Cologne, Germany.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2022 Jul 29; Vol. 377 (6605), pp. eabq3297. Date of Electronic Publication: 2022 Jul 29.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine Diphosphate*/metabolism
Adenosine Monophosphate*/metabolism
Arabidopsis*/enzymology
Arabidopsis*/immunology
Arabidopsis Proteins*/chemistry
Arabidopsis Proteins*/genetics
Arabidopsis Proteins*/metabolism
Carboxylic Ester Hydrolases*/chemistry
Carboxylic Ester Hydrolases*/genetics
Carboxylic Ester Hydrolases*/metabolism
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Plant Immunity*/genetics
Catalysis

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Skocz do pozycji: 5.

Tytuł:: Population pharmacokinetic modeling of GS-441524, the active metabolite of remdesivir, in Japanese COVID-19 patients with renal dysfunction.
Autorzy:: Sukeishi A; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.
Itohara K; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.
Yonezawa A; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Sato Y; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.
Matsumura K; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.
Katada Y; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.
Nakagawa T; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.
Hamada S; Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tanabe N; Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Imoto E; Shimadzu Corporation, Kyoto, Japan.
Kai S; Department of Anesthesia, Kyoto University Hospital, Kyoto, Japan.
Hirai T; Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yanagita M; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.
Ohtsuru S; Department of Primary Care and Emergency Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Terada T; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Kyoto, Japan.
Ito I; Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Pokaż więcej
Źródło:: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2022 Jan; Vol. 11 (1), pp. 94-103. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19 Drug Treatment*
Adenosine/*analogs & derivatives
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Kidney Diseases/*blood
Adenosine/blood ; Adenosine Monophosphate/administration & dosage ; Adenosine Monophosphate/pharmacokinetics ; Aged ; Aged, 80 and over ; Alanine/administration & dosage ; Alanine/pharmacokinetics ; Body Surface Area ; COVID-19/blood ; Drug Administration Schedule ; Extracorporeal Membrane Oxygenation ; Female ; Glomerular Filtration Rate ; Humans ; Japan ; Male ; Middle Aged ; Monte Carlo Method ; Precision Medicine ; Retrospective Studies

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Skocz do pozycji: 6.

Tytuł:: Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID-19.
Autorzy:: Biever P; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine II (Division of Infectious Diseases), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Staudacher DL; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Sommer MJ; Institute of Forensic Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Hermann Staudinger Graduate School, University of Freiburg, Freiburg, Germany.
Triebel H; Institute of Forensic Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Neukamm MA; Institute of Forensic Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Bode C; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Supady A; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany.
Lother A; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Pokaż więcej
Źródło:: Pharmacology research & perspectives [Pharmacol Res Perspect] 2021 Apr; Vol. 9 (2), pp. e00743.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
COVID-19/*therapy
Hemoperfusion/*instrumentation
Adenosine/analogs & derivatives ; Adenosine Monophosphate/blood ; Adenosine Monophosphate/pharmacokinetics ; Alanine/blood ; Alanine/pharmacokinetics ; Blood Chemical Analysis ; COVID-19/blood ; Chromatography, Liquid ; Combined Modality Therapy ; Furans/blood ; Furans/pharmacokinetics ; Hemoperfusion/adverse effects ; Humans ; Pyrroles/blood ; Pyrroles/pharmacokinetics ; Tandem Mass Spectrometry ; Triazines/blood ; Triazines/pharmacokinetics

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Skocz do pozycji: 7.

Tytuł:: The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections.
Autorzy:: Hickman MR; Joint Project Manager for Chemical, Biological, Radiological, and Nuclear Medical (JPM CBRN Medical), Fort Detrick, Maryland, United States of America.
Saunders DL; U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America.
Bigger CA; Logistics Management International Inc, Tysons Corner, Virginia, United States of America.
Kane CD; National Cancer Institute, Frederick, Maryland, United States of America.
Iversen PL; Oregon State University, Corvallis, Oregon, United States of America.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2022 Mar 08; Vol. 16 (3), pp. e0010220. Date of Electronic Publication: 2022 Mar 08 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms:: Drug Development*
Medical Countermeasures*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antiviral Agents/*pharmacology
Hemorrhagic Fevers, Viral/*drug therapy
RNA Virus Infections/*drug therapy
Adenosine Monophosphate/pharmacology ; Alanine/pharmacology ; Animals ; Humans ; Models, Animal ; Primates ; United States ; United States Food and Drug Administration/legislation & jurisprudence

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Skocz do pozycji: 8.

Tytuł:: Comparative outcomes of combined corticosteroid and remdesivir therapy with corticosteroid monotherapy in ventilated COVID-19 patients.
Autorzy:: Mandadi S; Department of Infectious Diseases, Charleston Area Medical Center, Charleston, West Virginia, United States of America.
Pulluru H; Department of Hospital Medicine, Charleston Area Medical Center, Charleston, West Virginia, United States of America.
Annie F; Charleston Area Medical Center Health Education and Research Institute, Charleston, West Virginia, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Feb 23; Vol. 17 (2), pp. e0264301. Date of Electronic Publication: 2022 Feb 23 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19 Drug Treatment*
Adenosine Monophosphate/*analogs & derivatives
Adrenal Cortex Hormones/*therapeutic use
Alanine/*analogs & derivatives
Adenosine Monophosphate/therapeutic use ; Aged ; Alanine/therapeutic use ; COVID-19/complications ; COVID-19/mortality ; COVID-19/virology ; Cohort Studies ; Drug Therapy, Combination ; Female ; Hospital Mortality ; Humans ; Incidence ; Kaplan-Meier Estimate ; Length of Stay ; Male ; Middle Aged ; Proportional Hazards Models ; Pseudomonas Infections/diagnosis ; Pseudomonas Infections/epidemiology ; Pseudomonas Infections/etiology ; Respiration, Artificial ; SARS-CoV-2/isolation & purification ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/epidemiology ; Staphylococcal Infections/etiology ; Treatment Outcome

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Skocz do pozycji: 9.

Tytuł:: Remdesivir in combination with dexamethasone for patients hospitalized with COVID-19: A retrospective multicenter study.
Autorzy:: Gressens SB; Département des Maladies Infectieuses, Hôpitaux Saint Louis-Lariboisière, Université de Paris, AP-HP, Paris, France.
Esnault V; Département des Maladies Infectieuses, Hôpitaux Saint Louis-Lariboisière, Université de Paris, AP-HP, Paris, France.
De Castro N; Département des Maladies Infectieuses, Hôpitaux Saint Louis-Lariboisière, Université de Paris, AP-HP, Paris, France.
Sellier P; Département des Maladies Infectieuses, Hôpitaux Saint Louis-Lariboisière, Université de Paris, AP-HP, Paris, France.
Sene D; Département de Médecine Interne, AP-HP Hôpital Lariboisière, Paris, France.
Chantelot L; Service de Pneumologie, AP-HP Hôpital Saint Louis, Paris, France.
Hervier B; UF de Médecine Interne, AP-HP Hôpital Saint Louis, Paris, France.
Delaugerre C; Laboratoire de Virologie, AP-HP Hôpital Saint Louis, Paris, France.
Chevret S; Service de Biostatistique et Information Médicale, AP-HP Hôpital Saint Louis, Paris, France.
Molina JM; Département des Maladies Infectieuses, Hôpitaux Saint Louis-Lariboisière, Université de Paris, AP-HP, Paris, France.; Pokaż więcej
Corporate Authors:: Saint-Louis CORE group
Źródło:: PloS one [PLoS One] 2022 Feb 17; Vol. 17 (2), pp. e0262564. Date of Electronic Publication: 2022 Feb 17 (Print Publication: 2022).
Typ publikacji:: Journal Article; Multicenter Study
MeSH Terms:: COVID-19 Drug Treatment*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Anti-Inflammatory Agents/*therapeutic use
Antiviral Agents/*therapeutic use
Dexamethasone/*therapeutic use
SARS-CoV-2/*drug effects
Adenosine Monophosphate/therapeutic use ; Aged ; Alanine/therapeutic use ; COVID-19/epidemiology ; COVID-19/mortality ; COVID-19/virology ; Drug Therapy, Combination ; Female ; Follow-Up Studies ; France/epidemiology ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; SARS-CoV-2/isolation & purification ; Survival Rate

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Skocz do pozycji: 10.

Tytuł:: Cardiovascular events and safety outcomes associated with remdesivir using a World Health Organization international pharmacovigilance database.
Autorzy:: Jung SY; Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Kim MS; College of Medicine, Korea University, Seoul, Korea.; Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Samsung Medical Center, Sungkyunkwan University, Seoul, Korea.
Li H; University of Florida College of Medicine, Gainesville, Florida, USA.
Lee KH; Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Koyanagi A; Research and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, CIBERSAM, Barcelona, Spain.; ICREA, Barcelona, Spain.; Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Solmi M; Department of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada.; Department of Mental Health, The Ottawa Hospital, Ottawa, Ontario, Canada.; Ottawa Hospital Research Institute (OHRI) Clinical Epidemiology Program, University of Ottawa, Ottawa, Ontario, Canada.
Kronbichler A; Department of Internal Medicine IV, Medical University Innsbruck, Innsbruck, Austria.
Dragioti E; Department of Health, Medicine and Caring Sciences, Pain and Rehabilitation Centre, Linköping University, Linköping, Sweden.
Tizaoui K; Laboratory Microorganismes and Active Biomolecules, Sciences Faculty of Tunis, Tunis El Manar University, Tunis, Tunisia.
Cargnin S; Department of Pharmaceutical Sciences, Interdepartmental Research Center of Pharmacogenetics and Pharmacogenomics (CRIFF), University of Piemonte Orientale, Novara, Italy.
Terrazzino S; Department of Pharmaceutical Sciences, Interdepartmental Research Center of Pharmacogenetics and Pharmacogenomics (CRIFF), University of Piemonte Orientale, Novara, Italy.
Hong SH; Yonsei University College of Medicine, Seoul, Korea.
Abou Ghayda R; Urology Institute, University Hospitals and Case Western Reserve University, Cleveland, Ohio, USA.
Kim NK; Department of Pediatrics, Emory University, Atlanta, Georgia, USA.; Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea.
Chung SK; College of Medicine, Ewha Womans University, Seoul, Korea.
Jacob L; Research and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, CIBERSAM, Barcelona, Spain.; Faculty of Medicine, University of Versailles Saint-Quentin-en-Yvelines, Montigny-le-Bretonneux, France.
Salem JE; Department of Pharmacology, INSERM, CIC-1901 Paris-Est, CLIP Galilée, UNICO-GRECO Cardio-oncology Program, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, Paris, France.
Yon DK; Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Korea.
Lee SW; Department of Data Science, Sejong University College of Software Convergence, Seoul, Korea.
Kostev K; University Clinic of Marburg, Marburg, Germany.
Kim AY; Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Jung JW; Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Choi JY; Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Shin JS; Infectious Disease Research Center, Korea Research Institute of Chemical Technology, Daejeon, Korea.
Park SJ; Stem Cell Research Institute, T&R Biofab Co. Ltd, Siheung, Korea.
Choi SW; Department of Physiology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea.
Ban K; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China.
Moon SH; Stem Cell Research Institute, T&R Biofab Co. Ltd, Siheung, Korea.
Go YY; Department of Infectious Diseases and Public Health, City University of Hong Kong, Hong Kong SAR, China.
Shin JI; Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Smith L; The Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, Cambridge, UK.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2022 Feb; Vol. 15 (2), pp. 501-513. Date of Electronic Publication: 2021 Oct 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Pharmacovigilance*
SARS-CoV-2*
COVID-19 Drug Treatment*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antiviral Agents/*adverse effects
Cardiovascular Diseases/*chemically induced
Adenosine Monophosphate/adverse effects ; Alanine/adverse effects ; Databases, Factual ; Humans ; Myocytes, Cardiac/drug effects ; Retrospective Studies ; World Health Organization

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Skocz do pozycji: 11.

Tytuł:: Remdesivir and dexamethasone as tools to relieve hospital care systems stressed by COVID-19: A modelling study on bed resources and budget impact.
Autorzy:: Béraud G; Infectious Diseases Department, University Hospital of Poitiers, Poitiers, France.
Timsit JF; APHP- Bichat Hospital-Medical and Infectious Diseases Intensive Care Unit, Paris, France.; IAME UMR 1137 Université de Paris (Paris-Diderot), Paris, France.
Leleu H; Public Health Expertise, Paris, France.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jan 12; Vol. 17 (1), pp. e0262462. Date of Electronic Publication: 2022 Jan 12 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antiviral Agents/*economics
Bed Occupancy/*economics
Dexamethasone/*economics
Adenosine Monophosphate/economics ; Adenosine Monophosphate/therapeutic use ; Alanine/economics ; Alanine/therapeutic use ; Antiviral Agents/therapeutic use ; Bed Occupancy/statistics & numerical data ; COVID-19/economics ; COVID-19/virology ; Dexamethasone/therapeutic use ; France ; Hospitalization/economics ; Hospitalization/statistics & numerical data ; Humans ; Intensive Care Units ; Length of Stay ; Models, Statistical ; SARS-CoV-2/isolation & purification ; COVID-19 Drug Treatment

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Skocz do pozycji: 12.

Tytuł:: Comparative assessment of favipiravir and remdesivir against human coronavirus NL63 in molecular docking and cell culture models.
Autorzy:: Wang Y; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-1005, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
Li P; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-1005, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
Rajpoot S; Department of Biosciences and Biomedical Engineering (BSBE), Indian Institute of Technology Indore (IITI), Simrol, Indore, 453552, MP, India.
Saqib U; Department of Chemistry, Indian Institute of Technology Indore (IITI), Simrol, Indore, 453552, MP, India.
Yu P; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-1005, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
Li Y; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-1005, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
Li Y; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-1005, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
Ma Z; Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Baig MS; Department of Biosciences and Biomedical Engineering (BSBE), Indian Institute of Technology Indore (IITI), Simrol, Indore, 453552, MP, India. .
Pan Q; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-1005, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Dec 06; Vol. 11 (1), pp. 23465. Date of Electronic Publication: 2021 Dec 06.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Amides/*chemistry
Antiviral Agents/*chemistry
Coronavirus NL63, Human/*enzymology
Pyrazines/*chemistry
RNA-Dependent RNA Polymerase/*chemistry
Adenosine Monophosphate/chemistry ; Adenosine Monophosphate/metabolism ; Adenosine Monophosphate/pharmacology ; Alanine/chemistry ; Alanine/metabolism ; Alanine/pharmacology ; Amides/metabolism ; Amides/pharmacology ; Animals ; Antiviral Agents/metabolism ; Antiviral Agents/pharmacology ; Binding Sites ; Cell Culture Techniques ; Cell Line ; Coronavirus NL63, Human/physiology ; Haplorhini ; Humans ; Molecular Docking Simulation ; Pyrazines/metabolism ; Pyrazines/pharmacology ; RNA-Dependent RNA Polymerase/metabolism ; Virus Replication/drug effects

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Skocz do pozycji: 13.

Tytuł:: AMP-Activated Protein Kinase: Do We Need Activators or Inhibitors to Treat or Prevent Cancer?
Autorzy:: Russell FM; Division of Cell Signalling & Immunology, School of Life Sciences, University of Dundee, Dow Street, Dundee, Scotland DD1 5EH, UK.
Hardie DG; Division of Cell Signalling & Immunology, School of Life Sciences, University of Dundee, Dow Street, Dundee, Scotland DD1 5EH, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Dec 27; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 27.
Typ publikacji:: Journal Article; Review
MeSH Terms:: AMP-Activated Protein Kinases/*antagonists & inhibitors
AMP-Activated Protein Kinases/*metabolism
Adenosine Monophosphate/*pharmacology
Energy Metabolism/*physiology
Neoplasms/*metabolism
Protein Kinase Inhibitors/*pharmacology
Signal Transduction/*drug effects
AMP-Activated Protein Kinases/chemistry ; AMP-Activated Protein Kinases/genetics ; Adenosine Monophosphate/analogs & derivatives ; Adenosine Triphosphate/biosynthesis ; Animals ; Calcium-Calmodulin-Dependent Protein Kinase Kinase/metabolism ; DNA Damage/genetics ; DNA Damage/physiology ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Humans ; Neoplasms/drug therapy ; Neoplasms/genetics ; Phosphorylation/drug effects ; Signal Transduction/genetics ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism

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Skocz do pozycji: 14.

Tytuł:: Quantitative HPLC-MS/MS determination of Nuc, the active metabolite of remdesivir, and its pharmacokinetics in rat.
Autorzy:: Du P; Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, Beijing, 100020, People's Republic of China. .
Wang G; Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, Beijing, 100020, People's Republic of China.
Yang S; Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, Beijing, 100020, People's Republic of China.
Li P; Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, Beijing, 100020, People's Republic of China.
Liu L; Department of Pharmacy, Beijing Chao-Yang Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, Beijing, 100020, People's Republic of China. .; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Sep; Vol. 413 (23), pp. 5811-5820. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine/*analogs & derivatives
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antiviral Agents/*blood
Chromatography, High Pressure Liquid/*methods
Tandem Mass Spectrometry/*methods
Adenosine/blood ; Adenosine/pharmacokinetics ; Adenosine/standards ; Adenosine Monophosphate/blood ; Adenosine Monophosphate/pharmacokinetics ; Adenosine Monophosphate/standards ; Alanine/blood ; Alanine/pharmacokinetics ; Alanine/standards ; Animals ; Antiviral Agents/pharmacokinetics ; Antiviral Agents/standards ; Limit of Detection ; Male ; Quality Control ; Rats ; Rats, Sprague-Dawley ; Reference Standards ; Reproducibility of Results

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Skocz do pozycji: 15.

Tytuł:: Real-world treatment patterns and clinical outcomes for inpatients with COVID-19 in the US from September 2020 to February 2021.
Autorzy:: Ayodele O; Data Sciences Institute, Takeda Pharmaceutical Company Limited, Cambridge, MA, United States of America.
Ren K; Data Sciences Institute, Takeda Pharmaceutical Company Limited, Cambridge, MA, United States of America.
Zhao J; Analysis Group, Data Sciences Institute, Boston, MA, United States of America.
Signorovitch J; Analysis Group, Data Sciences Institute, Boston, MA, United States of America.
Jonsson Funk M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, United States of America.
Zhu J; Center for Observational Research and Data Science, Bristol-Myers Squibb, Princeton, NJ, United States of America.
Bao Y; Center for Observational Research and Data Science, Bristol-Myers Squibb, Princeton, NJ, United States of America.
Gondek K; Data Sciences Institute, Takeda Pharmaceutical Company Limited, Cambridge, MA, United States of America.
Keenan H; Data Sciences Institute, Takeda Pharmaceutical Company Limited, Cambridge, MA, United States of America.; Pokaż więcej
Corporate Authors:: R&D COVID Alliance
Źródło:: PloS one [PLoS One] 2021 Dec 28; Vol. 16 (12), pp. e0261707. Date of Electronic Publication: 2021 Dec 28 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Patient Discharge*
COVID-19 Drug Treatment*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Anti-Inflammatory Agents/*therapeutic use
Antiviral Agents/*therapeutic use
Dexamethasone/*therapeutic use
Hypertension/*epidemiology
Obesity/*epidemiology
SARS-CoV-2/*genetics
SARS-CoV-2/*immunology
Adenosine Monophosphate/therapeutic use ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alanine/therapeutic use ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/virology ; Comorbidity ; Drug Therapy, Combination/methods ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; RNA, Viral/genetics ; Retrospective Studies ; Treatment Outcome ; United States/epidemiology ; Young Adult

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Skocz do pozycji: 16.

Tytuł:: Retrospective evaluation of seven different treatment protocols in hospitalized COVID-19 patients
Autorzy:: Demir Önder K; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Antalya Training and Research Hospital, Antalya, Turkey.
Seremet Keskin A; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Antalya Training and Research Hospital, Antalya, Turkey.
Berk H; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Antalya Training and Research Hospital, Antalya, Turkey.
Seyman D; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Antalya Training and Research Hospital, Antalya, Turkey.
Öztoprak N; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Antalya Training and Research Hospital, Antalya, Turkey.; Pokaż więcej
Źródło:: Turkish journal of medical sciences [Turk J Med Sci] 2021 Dec 13; Vol. 51 (6), pp. 2835-2849. Date of Electronic Publication: 2021 Dec 13.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Amides/*therapeutic use
Antiviral Agents/*therapeutic use
COVID-19/*diagnosis
COVID-19/*therapy
Hydroxychloroquine/*therapeutic use
Oseltamivir/*therapeutic use
Pyrazines/*therapeutic use
Respiration, Artificial/*methods
Adenosine Monophosphate/therapeutic use ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alanine/therapeutic use ; COVID-19/mortality ; COVID-19 Nucleic Acid Testing ; Clinical Protocols ; Female ; Humans ; Length of Stay ; Male ; Middle Aged ; Pandemics ; Retrospective Studies ; SARS-CoV-2/isolation & purification ; Treatment Outcome ; Young Adult

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Skocz do pozycji: 17.

Tytuł:: Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9.
Autorzy:: Lerum TV; Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Nydalen, Postboks 4950, 0424, Oslo, Norway. .; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway. .
Maltzahn NN; Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.; Department of Biostatistics, Oslo Centre for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway.
Aukrust P; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.
Trøseid M; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway.
Henriksen KN; Department of Haematology, Oslo University Hospital, Oslo, Norway.; Hospital Pharmacies of South-Eastern Norway Enterprise, Oslo, Norway.
Kåsine T; Division of Critical Care and Emergencies, Oslo University Hospital, Oslo, Norway.
Dyrhol-Riise AM; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital, Ullevål, Oslo, Norway.
Stiksrud B; Department of Infectious Diseases, Oslo University Hospital, Ullevål, Oslo, Norway.
Haugli M; Infectious Diseases Department, Sørlandet Hospital SSK, Kristiansand, Norway.
Blomberg B; Department of Medicine, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway.
Kittang BR; Department of Medicine, Haraldsplass Deaconess Hospital, Bergen, Norway.
Johannessen A; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Department of Infectious Diseases, Vestfold Hospital Trust, Tønsberg, Norway.
Hannula R; Department of Infectious Diseases, Trondheim University Hospital, Trondheim, Norway.
Aballi S; Department of Infectious Diseases, Østfold Hospital Trust Kalnes, Grålum, Norway.
Kildal AB; Department of Anaesthesiology and Intensive Care, University Hospital of North Norway, Tromsø, Norway.
Eiken R; Department of Infectious Diseases, Innlandet Hospital Trust, Lillehammer, Norway.
Dahl TB; Division of Critical Care and Emergencies, Oslo University Hospital, Oslo, Norway.; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.
Lund-Johansen F; Division of Laboratory Medicine, Department of Immunology, Oslo University Hospital, Oslo, Norway.
Müller F; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway.
Rodriguez JR; Department of Radiology and Nuclear Medicine, Oslo University Hospital Ullevål, Oslo, Norway.
Meltzer C; Department of Radiology and Nuclear Medicine, Oslo University Hospital Ullevål, Oslo, Norway.
Einvik G; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Department of Pulmonary Medicine, Akershus University Hospital, Lørenskog, Norway.
Ueland T; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.
Olsen IC; Department of Research Support for Clinical Trials, Oslo University Hospital, Oslo, Norway.
Barratt-Due A; Division of Critical Care and Emergencies, Oslo University Hospital, Oslo, Norway.; Department of Immunology, University of Oslo, Oslo, Norway.
Aaløkken TM; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital Ullevål, Oslo, Norway.
Skjønsberg OH; Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Nydalen, Postboks 4950, 0424, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Blindern, Postboks 1171, 0318, Oslo, Norway.; Pokaż więcej
Corporate Authors:: NOR-SOLIDARITY Consortium
Źródło:: Scientific reports [Sci Rep] 2021 Dec 01; Vol. 11 (1), pp. 23205. Date of Electronic Publication: 2021 Dec 01.
Typ publikacji:: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: Viral Load*
COVID-19 Drug Treatment*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Hydroxychloroquine/*adverse effects
Lung Diseases/*pathology
Matrix Metalloproteinase 9/*metabolism
SARS-CoV-2/*drug effects
Adenosine Monophosphate/adverse effects ; Aged ; Alanine/adverse effects ; Antibody Formation ; Antimalarials/adverse effects ; Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; COVID-19/virology ; Female ; Hospitalization ; Humans ; Lung Diseases/chemically induced ; Lung Diseases/enzymology ; Lung Diseases/virology ; Male ; Middle Aged ; Severity of Illness Index

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Skocz do pozycji: 18.

Tytuł:: Protocol: Benefits and harms of remdesivir for COVID-19 in adults: A systematic review with meta-analysis.
Autorzy:: Paludan-Müller AS; Department of Clinical Research, Centre for Evidence-Based Medicine Odense (CEBMO) and Cochrane Denmark, University of Southern Denmark, Odense, Denmark.; Open Patient Data Exploratory Network (OPEN), Odense University Hospital, Odense, Denmark.
Lundh A; Department of Clinical Research, Centre for Evidence-Based Medicine Odense (CEBMO) and Cochrane Denmark, University of Southern Denmark, Odense, Denmark.; Open Patient Data Exploratory Network (OPEN), Odense University Hospital, Odense, Denmark.; Department of Infectious Diseases, Hvidovre University Hospital, Hvidovre, Denmark.
Page MJ; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Munkholm K; Department of Clinical Research, Centre for Evidence-Based Medicine Odense (CEBMO) and Cochrane Denmark, University of Southern Denmark, Odense, Denmark.; Open Patient Data Exploratory Network (OPEN), Odense University Hospital, Odense, Denmark.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Nov 29; Vol. 16 (11), pp. e0260544. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:: COVID-19 Drug Treatment*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Adenosine Monophosphate/therapeutic use ; Adult ; Alanine/therapeutic use ; Humans ; Publication Bias ; Risk

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Skocz do pozycji: 19.

Tytuł:: Evaluation of the therapeutic regimen in COVID-19 in transplant patients: where do immunomodulatory and antivirals stand?
Autorzy:: Shafiekhani M; Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Shahabinezhad F; Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Niknam T; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Tara SA; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Haem E; Department of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Mardani P; Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.
Zare Z; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Jafarian S; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Mirzad Jahromi K; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Arabsheybani S; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Moeini YS; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Alavi J; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Jalali SS; Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Salimi M; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Shahriarirad R; Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. .
Malekhosseini SA; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.; Pokaż więcej
Źródło:: Virology journal [Virol J] 2021 Nov 22; Vol. 18 (1), pp. 228. Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: Transplant Recipients*
COVID-19 Drug Treatment*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antibodies, Monoclonal, Humanized/*therapeutic use
Antiviral Agents/*therapeutic use
Immunologic Factors/*therapeutic use
SARS-CoV-2/*isolation & purification
Adenosine Monophosphate/therapeutic use ; Aged ; Alanine/therapeutic use ; COVID-19/diagnosis ; COVID-19/mortality ; COVID-19 Nucleic Acid Testing ; COVID-19 Testing ; Female ; Humans ; Iran/epidemiology ; Length of Stay ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2/genetics

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Skocz do pozycji: 20.

Tytuł:: Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets.
Autorzy:: Cheng K; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Biological Sciences Graduate Program (BISI), University of Maryland, College Park, MD, USA.
Martin-Sancho L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Pal LR; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.
Pu Y; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Riva L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Yin X; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Sinha S; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Biological Sciences Graduate Program (BISI), University of Maryland, College Park, MD, USA.
Nair NU; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.
Chanda SK; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Ruppin E; Cancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.; Department of Computer Science, University of Maryland, College Park, MD, USA.; Pokaż więcej
Źródło:: Molecular systems biology [Mol Syst Biol] 2021 Nov; Vol. 17 (11), pp. e10260.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Pandemics*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antiviral Agents/*therapeutic use
COVID-19/*metabolism
Metabolic Networks and Pathways/*genetics
SARS-CoV-2/*physiology
Adenosine Monophosphate/therapeutic use ; Alanine/therapeutic use ; Animals ; COVID-19/virology ; Caco-2 Cells ; Chlorocebus aethiops ; Datasets as Topic ; Drug Development ; Drug Repositioning ; Host-Pathogen Interactions ; Humans ; RNA, Small Interfering ; Sequence Analysis, RNA ; Vero Cells ; COVID-19 Drug Treatment

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