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Wyszukujesz frazę ""alpha-Glucosidases"" wg kryterium: Temat


Tytuł :
Characterization of an α-Glucosidase Enzyme Conserved in Gardnerella spp. Isolated from the Human Vaginal Microbiome.
Autorzy :
Bhandari P; Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewangrid.25152.31, Saskatoon, Saskatchewan, Canada.
Tingley JP; Lethbridge Research and Development Centre, Agriculture and Agri-Food Canada, Lethbridge, Alberta, Canada.; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, Canada.
Palmer DRJ; Department of Chemistry, University of Saskatchewangrid.25152.31, Saskatoon, Saskatchewan, Canada.
Abbott DW; Lethbridge Research and Development Centre, Agriculture and Agri-Food Canada, Lethbridge, Alberta, Canada.; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, Canada.
Hill JE; Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewangrid.25152.31, Saskatoon, Saskatchewan, Canada.
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Źródło :
Journal of bacteriology [J Bacteriol] 2021 Aug 09; Vol. 203 (17), pp. e0021321. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microbiota*
Bacterial Proteins/*chemistry
Gardnerella/*enzymology
Gardnerella/*isolation & purification
Vagina/*microbiology
alpha-Glucosidases/*chemistry
Amino Acid Sequence ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Enzyme Stability ; Female ; Gardnerella/classification ; Gardnerella/genetics ; Humans ; Hydrogen-Ion Concentration ; Kinetics ; Phylogeny ; Sequence Alignment ; Temperature ; alpha-Glucosidases/genetics ; alpha-Glucosidases/metabolism
Czasopismo naukowe
Tytuł :
Natural α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitors: A Source of Scaffold Molecules for Synthesis of New Multitarget Antidiabetic Drugs.
Autorzy :
Genovese M; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50139 Florence, Italy.
Nesi I; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50139 Florence, Italy.
Caselli A; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50139 Florence, Italy.
Paoli P; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50139 Florence, Italy.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 09; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Enzyme Inhibitors/*chemistry
Hypoglycemic Agents/*chemistry
Protein Tyrosine Phosphatase, Non-Receptor Type 1/*antagonists & inhibitors
alpha-Glucosidases/*drug effects
Diabetes Mellitus, Type 2/drug therapy ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/therapeutic use ; Glycoside Hydrolase Inhibitors/chemical synthesis ; Glycoside Hydrolase Inhibitors/chemistry ; Glycoside Hydrolase Inhibitors/therapeutic use ; Humans ; Hypoglycemic Agents/chemical synthesis ; Hypoglycemic Agents/therapeutic use ; Protein Tyrosine Phosphatase, Non-Receptor Type 1/chemistry ; Protein Tyrosine Phosphatase, Non-Receptor Type 1/genetics ; alpha-Glucosidases/chemistry ; alpha-Glucosidases/genetics
Czasopismo naukowe
Tytuł :
Inhibition Mechanism of α-Amylase/α-Glucosidase by Silibinin, Its Synergism with Acarbose, and the Effect of Milk Proteins.
Autorzy :
Yang J; School of Life Sciences, Tianjin University, Tianjin 300072, People's Republic of China.
Li H; School of Life Sciences, Tianjin University, Tianjin 300072, People's Republic of China.
Wang X; School of Life Sciences, Tianjin University, Tianjin 300072, People's Republic of China.
Zhang C; School of Life Sciences, Tianjin University, Tianjin 300072, People's Republic of China.
Feng G; School of Life Sciences, Tianjin University, Tianjin 300072, People's Republic of China.
Peng X; School of Life Sciences, Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, Tianjin University, Tianjin 300072, People's Republic of China.; Key Laboratory of Tropical Medicinal Resources Chemistry of Ministry of Education, Hainan Normal University, Haikou, Hainan 571158, People's Republic of China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Sep 15; Vol. 69 (36), pp. 10515-10526. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article
MeSH Terms :
Acarbose*/pharmacology
alpha-Glucosidases*
Amylases ; Glucosidases ; Glycoside Hydrolase Inhibitors ; Milk Proteins ; Silybin ; alpha-Amylases
Czasopismo naukowe
Tytuł :
α-glucosidase immobilization on magnetic core-shell metal-organic frameworks for inhibitor screening from traditional Chinese medicines.
Autorzy :
Wan GZ; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Ma XH; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, 730000, China.
Jin L; College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, 730000, China. Electronic address: .
Chen J; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2021 Sep; Vol. 205, pp. 111847. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Metal-Organic Frameworks*
alpha-Glucosidases*
China ; Enzymes, Immobilized ; Glycoside Hydrolase Inhibitors/pharmacology ; Magnetic Phenomena ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł :
Number of galloyl moiety and intramolecular bonds in galloyl-based polyphenols affect their interaction with alpha-glucosidase.
Autorzy :
Cao J; College of Food Science and Engineering, Northwest A & F University, Yangling, Shaanxi 712100, PR China.
Yan S; College of Food Science and Engineering, Northwest A & F University, Yangling, Shaanxi 712100, PR China.
Xiao Y; College of Food Science and Engineering, Northwest A & F University, Yangling, Shaanxi 712100, PR China.
Han L; College of Food Science and Engineering, Northwest A & F University, Yangling, Shaanxi 712100, PR China.
Sun L; College of Food Science and Engineering, Northwest A & F University, Yangling, Shaanxi 712100, PR China. Electronic address: .
Wang M; College of Food Science and Engineering, Northwest A & F University, Yangling, Shaanxi 712100, PR China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2022 Jan 15; Vol. 367, pp. 129846. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*
alpha-Glucosidases*
Glycoside Hydrolase Inhibitors ; Humans ; Molecular Docking Simulation ; Polyphenols
Czasopismo naukowe
Tytuł :
Three-dimensional tissue-engineered human skeletal muscle model of Pompe disease.
Autorzy :
Wang J; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Zhou CJ; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Khodabukus A; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Tran S; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Han SO; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Carlson AL; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Madden L; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Kishnani PS; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Koeberl DD; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Bursac N; Department of Biomedical Engineering, Duke University, Durham, NC, USA. .
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Źródło :
Communications biology [Commun Biol] 2021 May 05; Vol. 4 (1), pp. 524. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Disease Models, Animal*
Muscle Contraction*
Glycogen Storage Disease Type II/*therapy
Muscle, Skeletal/*cytology
Myocardium/*cytology
Tissue Engineering/*methods
alpha-Glucosidases/*metabolism
Animals ; Dependovirus/genetics ; Glycogen/metabolism ; Glycogen Storage Disease Type II/metabolism ; Glycogen Storage Disease Type II/pathology ; Lysosomes/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle Development ; Muscle, Skeletal/metabolism ; Myocardium/metabolism ; alpha-Glucosidases/administration & dosage ; alpha-Glucosidases/genetics
Czasopismo naukowe
Tytuł :
Concentration effects on optical properties, DFT, crystal characterization and α-glucosidase activity studies: Novel Zn(II) complex.
Autorzy :
Dege N; Ondokuz Mayıs University, Faculty of Arts and Sciences, Department of Physics, 55139 Samsun, Turkey.
Özge Ö; Sakarya University, Faculty of Arts and Sciences, Department of Physics, 54187 Sakarya, Turkey.
Avcı D; Sakarya University, Faculty of Arts and Sciences, Department of Physics, 54187 Sakarya, Turkey. Electronic address: .
Başoğlu A; Sakarya University, Faculty of Arts and Sciences, Department of Physics, 54187 Sakarya, Turkey. Electronic address: .
Sönmez F; Sakarya University of Applied Sciences, Pamukova Vocational High School, 54055 Sakarya, Turkey.
Yaman M; Ondokuz Mayıs University, Faculty of Arts and Sciences, Department of Physics, 55139 Samsun, Turkey.
Tamer Ö; Sakarya University, Faculty of Arts and Sciences, Department of Physics, 54187 Sakarya, Turkey.
Atalay Y; Sakarya University, Faculty of Arts and Sciences, Department of Physics, 54187 Sakarya, Turkey.
Zengin Kurt B; Bezmialem Vakif University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 34093 Istanbul, Turkey.
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Źródło :
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2021 Dec 05; Vol. 262, pp. 120072. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Refractometry*
alpha-Glucosidases*
Spectroscopy, Fourier Transform Infrared ; Zinc
Czasopismo naukowe
Tytuł :
Suppression of Bta11975, an α-glucosidase, by RNA interference reduces transmission of tomato chlorosis virus by Bemisia tabaci.
Autorzy :
Lu D; Subcollege of Longping, Graduate School of Hunan University, Changsha, China.; Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, China.
Yue H; Subcollege of Longping, Graduate School of Hunan University, Changsha, China.; Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, China.
Huang L; Subcollege of Longping, Graduate School of Hunan University, Changsha, China.; Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, China.
Zhang D; Subcollege of Longping, Graduate School of Hunan University, Changsha, China.; Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, China.
Zhang Z; Institute of Vegetable, Hunan Academy of Agricultural Sciences, Changsha, China.
Zhang Z; Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, China.
Zhang Y; Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Li F; College of Plant Protection, Yunnan Agricultural University, Kunming, China.
Yan F; Institute of Plant Virology, Ningbo University, Ningbo, China.
Zhou X; Department of Entomology, University of Kentucky, Lexington, KY, USA.
Shi X; Subcollege of Longping, Graduate School of Hunan University, Changsha, China.; Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, China.
Liu Y; Subcollege of Longping, Graduate School of Hunan University, Changsha, China.; Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, China.
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Źródło :
Pest management science [Pest Manag Sci] 2021 Nov; Vol. 77 (11), pp. 5294-5303. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Hemiptera*/genetics
alpha-Glucosidases*
Animals ; Crinivirus ; Plant Diseases ; RNA Interference
SCR Organism :
Tomato chlorosis virus
Czasopismo naukowe
Tytuł :
Comment on "Phenolic profiling and evaluation of in vitro antioxidant, α-glucosidase and α-amylase inhibitory activities of Lepisanthes fruticosa (Roxb) Leenh fruit extracts".
Autorzy :
Beszterda M; Poznań University of Life Sciences, Department of Food Biochemistry and Analysis, Mazowiecka 48, 60-623 Poznań, Poland.
Frański R; Adam Mickiewicz University, Faculty of Chemistry, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Nov 01; Vol. 361, pp. 130107. Date of Electronic Publication: 2021 May 15.
Typ publikacji :
Letter; Comment
MeSH Terms :
Antioxidants*
alpha-Glucosidases*
Fruit ; Plant Extracts ; alpha-Amylases
Opinia redakcyjna
Tytuł :
Inhibitory Activity and Mechanism Investigation of Hypericin as a Novel α -Glucosidase Inhibitor.
Autorzy :
Dong Q; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining 810008, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Hu N; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining 810008, China.
Yue H; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining 810008, China.
Wang H; CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining 810008, China.; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining 810008, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 28; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Anthracenes/*chemistry
Fungal Proteins/*antagonists & inhibitors
Glycoside Hydrolase Inhibitors/*chemistry
Hypoglycemic Agents/*chemistry
Perylene/*analogs & derivatives
alpha-Glucosidases/*chemistry
Anthracenes/metabolism ; Binding Sites ; Fungal Proteins/chemistry ; Fungal Proteins/metabolism ; Glycoside Hydrolase Inhibitors/metabolism ; Humans ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Hypoglycemic Agents/metabolism ; Kinetics ; Molecular Docking Simulation ; Nitrophenylgalactosides/chemistry ; Nitrophenylgalactosides/metabolism ; Perylene/chemistry ; Perylene/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Saccharomyces cerevisiae/classification ; Saccharomyces cerevisiae/enzymology ; Surface Plasmon Resonance ; alpha-Glucosidases/metabolism
Czasopismo naukowe
Tytuł :
Screening of in vitro and in silico α-amylase, α-glucosidase, and lipase inhibitory activity of oxyprenylated natural compounds and semisynthetic derivatives.
Autorzy :
Faraone I; Department of Science, University of Basilicata, via dell'Ateneo Lucano 10, 85100, Potenza, Italy; SpinoffBioActiPlant s.r.l., via dell'Ateneo Lucano 10, 85100, Potenza, Italy.
Russo D; Department of Science, University of Basilicata, via dell'Ateneo Lucano 10, 85100, Potenza, Italy; SpinoffBioActiPlant s.r.l., via dell'Ateneo Lucano 10, 85100, Potenza, Italy.
Genovese S; Department of Pharmacy, University Gabriele D'Annunzio of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy.
Milella L; Department of Science, University of Basilicata, via dell'Ateneo Lucano 10, 85100, Potenza, Italy. Electronic address: .
Monné M; Department of Science, University of Basilicata, via dell'Ateneo Lucano 10, 85100, Potenza, Italy.
Epifano F; Department of Pharmacy, University Gabriele D'Annunzio of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy. Electronic address: .
Fiorito S; Department of Pharmacy, University Gabriele D'Annunzio of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy.
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Źródło :
Phytochemistry [Phytochemistry] 2021 Jul; Vol. 187, pp. 112781. Date of Electronic Publication: 2021 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
alpha-Amylases*
alpha-Glucosidases*
Computer Simulation ; Glycoside Hydrolase Inhibitors/pharmacology ; Lipase ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł :
Thermal treatment enhances the α-glucosidase inhibitory activity of bitter melon (Momordica charantia) by increasing the free form of phenolic compounds and the contents of Maillard reaction products.
Autorzy :
Hsieh HJ; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan.
Lin JA; Graduate Institute of Food Safety, National Chung Hsing University, Taichung, Taiwan.
Chen KT; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan.
Cheng KC; Institute of Biotechnology, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Food Science and Technology, National Taiwan University, Taipei, Taiwan.; Department of Optometry, Asia University, Taichung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Hsieh CW; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.
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Źródło :
Journal of food science [J Food Sci] 2021 Jul; Vol. 86 (7), pp. 3109-3121. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Hot Temperature*
Antioxidants/*pharmacology
Glycation End Products, Advanced/*metabolism
Momordica charantia/*chemistry
Phenols/*metabolism
Plant Extracts/*pharmacology
alpha-Glucosidases/*pharmacology
Antioxidants/chemistry ; Glycation End Products, Advanced/analysis ; Phenols/analysis ; Plant Extracts/chemistry ; alpha-Glucosidases/chemistry
Czasopismo naukowe
Tytuł :
Nutritional composition and proteomic analysis of soft-shelled turtle (Pelodiscus sinensis) egg and identification of oligopeptides with alpha-glucosidase inhibitory activity.
Autorzy :
Qiu L; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China.
Deng Z; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China; Institute for Advanced Study, University of Nanchang, Nanchang 330031, Jiangxi, PR China.
Zhao C; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China.
Xiao T; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China.
Weng C; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China.
Li J; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China.
Zheng L; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China. Electronic address: .
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2021 Jul; Vol. 145, pp. 110414. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Turtles*
alpha-Glucosidases*
Animals ; Molecular Docking Simulation ; Oligopeptides ; Proteomics ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Gene duplication and subsequent functional diversification of maltase in fig wasp (Chalcidoidea, Hymenoptera).
Autorzy :
Wei X; Institute of Entomology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Li J; Institute of Entomology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Xiao J; Institute of Entomology, College of Life Sciences, Nankai University, Tianjin 300071, China. Electronic address: .
Huang D; Institute of Entomology, College of Life Sciences, Nankai University, Tianjin 300071, China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 01; Vol. 182, pp. 482-491. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Gene Duplication*
Insect Proteins/*genetics
alpha-Glucosidases/*genetics
Animals ; Binding Sites ; Insect Proteins/metabolism ; Life History Traits ; Protein Domains ; Wasps/classification ; Wasps/enzymology ; Wasps/genetics ; alpha-Glucosidases/metabolism
Czasopismo naukowe
Tytuł :
Immobilized lipase catalytic synthesis of phenolamides and their potential against α-glucosidase.
Autorzy :
Zeng F; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources and Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China.
Zhang H; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources and Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China.
Xu M; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources and Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China.
Huang K; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources and Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China.
Zhang T; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources and Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China.
Duan J; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources and Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, PR China. Electronic address: .
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Źródło :
Journal of biotechnology [J Biotechnol] 2021 Jun 20; Vol. 334, pp. 51-57. Date of Electronic Publication: 2021 Apr 18.
Typ publikacji :
Journal Article
MeSH Terms :
Glycoside Hydrolase Inhibitors*/pharmacology
alpha-Glucosidases*/metabolism
Glucosidases ; Lipase ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Comparative study of inhibition mechanisms of structurally different flavonoid compounds on α-glucosidase and synergistic effect with acarbose.
Autorzy :
Yang J; School of Life Sciences, Tianjin University, Tianjin 300072, PR China.
Wang X; School of Life Sciences, Tianjin University, Tianjin 300072, PR China.
Zhang C; School of Life Sciences, Tianjin University, Tianjin 300072, PR China.
Ma L; Shaanxi Zhuyuanbang Medical Technology Co., Ltd, Xi'an 710048, PR China.
Wei T; Shaanxi Zhuyuanbang Medical Technology Co., Ltd, Xi'an 710048, PR China.
Zhao Y; School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, PR China.
Peng X; School of Life Sciences, Tianjin University, Tianjin 300072, PR China; Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, Tianjin University, Tianjin 300072, PR China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Jun 15; Vol. 347, pp. 129056. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Acarbose/*chemistry
Flavonoids/*chemistry
Glycoside Hydrolase Inhibitors/*chemistry
alpha-Glucosidases/*chemistry
Acarbose/metabolism ; Apigenin/chemistry ; Apigenin/metabolism ; Binding Sites ; Diabetes Mellitus/drug therapy ; Drug Synergism ; Flavones/chemistry ; Flavones/metabolism ; Flavonoids/metabolism ; Flavonoids/therapeutic use ; Glycoside Hydrolase Inhibitors/metabolism ; Glycoside Hydrolase Inhibitors/therapeutic use ; Humans ; Kinetics ; Molecular Docking Simulation ; Thermodynamics ; alpha-Glucosidases/metabolism
Czasopismo naukowe
Tytuł :
Reusable Fluorescent Nanobiosensor Integrated in a Multiwell Plate for Screening and Quantification of Antidiabetic Drugs.
Autorzy :
Alacid Y; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain.
Martínez-Tomé MJ; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain.
Mateo CR; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Jun 09; Vol. 13 (22), pp. 25624-25634. Date of Electronic Publication: 2021 May 27.
Typ publikacji :
Journal Article
MeSH Terms :
Fluorescence*
Biosensing Techniques/*methods
Glycoside Hydrolase Inhibitors/*pharmacology
Hypoglycemic Agents/*pharmacology
Nanoparticles/*administration & dosage
Polymers/*chemistry
alpha-Glucosidases/*chemistry
Acarbose/pharmacology ; Fluorenes/chemistry ; Fluorescent Dyes ; Glycoside Hydrolase Inhibitors/isolation & purification ; Humans ; Hypoglycemic Agents/isolation & purification ; Liposomes/chemistry ; Nanoparticles/chemistry ; alpha-Glucosidases/analysis
Czasopismo naukowe
Tytuł :
Asperflaloids A and B from Aspergillus   flavipes DZ-3, an Endophytic Fungus of Eucommia   ulmoides Oliver.
Autorzy :
Liu W; School of Pharmacy, Henan University, Kaifeng 475004, China.
Liu Y; School of Pharmacy, Henan University, Kaifeng 475004, China.
Yang F; School of Pharmacy, Henan University, Kaifeng 475004, China.
Han S; School of Pharmacy, Henan University, Kaifeng 475004, China.
Zhang J; School of Pharmacy, Henan University, Kaifeng 475004, China.
Yang H; School of Pharmacy, Henan University, Kaifeng 475004, China.
Cheng Z; School of Pharmacy, Henan University, Kaifeng 475004, China.; Eucommia Ulmoides Cultivation and Utilization of Henan Engineering Laboratory, Kaifeng 475004, China.
Li Q; School of Pharmacy, Henan University, Kaifeng 475004, China.; Eucommia Ulmoides Cultivation and Utilization of Henan Engineering Laboratory, Kaifeng 475004, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 09; Vol. 26 (12). Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids/*chemistry
Antioxidants/*pharmacology
Aspergillus/*chemistry
Eucommiaceae/*microbiology
alpha-Glucosidases/*chemistry
Alkaloids/pharmacology ; Antioxidants/chemistry ; alpha-Glucosidases/metabolism
SCR Organism :
Aspergillus flavipes
Czasopismo naukowe
Tytuł :
Irreversible thermal inactivation and conformational lock of alpha glucosidase.
Autorzy :
Alaei L; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Department of Biology and Biotechnology, Faculty of Sciences, University of Kurdistan, Sanandaj, Iran.
Izadi Z; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Zistmavad Pharmed Co, Tehran, Iran.
Jafari S; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Zistmavad Pharmed Co, Tehran, Iran.
Jahanshahi F; Student research committee, Faculty of Medicine, Iran University of Medical Science, Tehran, Iran.
Jaymand M; Nano Drug Delivery Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mohammadi P; Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Paray BA; Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Hasan A; Department of Mechanical and Industrial Engineering, College of Engineering, Qatar University, Doha, Qatar.; Biomedical Research Center, Qatar University, Doha, Qatar.
Falahati M; Department of Nanotechnology, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Varnamkhasti BS; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Zistmavad Pharmed Co, Tehran, Iran.
Saboury AA; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Moosavi-Nejad Z; Department of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran.
Sheikh-Hosseini M; Department of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran.
Derakhshankhah H; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Zistmavad Pharmed Co, Tehran, Iran.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Jun; Vol. 39 (9), pp. 3256-3262. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
alpha-Glucosidases*/metabolism
Enzyme Stability ; Hydrogen-Ion Concentration ; Kinetics ; Protein Conformation ; Temperature
Czasopismo naukowe
Tytuł :
New ent-kaurane diterpenes from the roasted arabica coffee beans and molecular docking to α-glucosidase.
Autorzy :
Hu G; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Peng X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China.
Dong D; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China; Key Laboratory of Animal Models and Human Disease Mechanisms, and Ion Channel Research and Drug Development Center, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People's Republic of China.
Nian Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Gao Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Wang X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China.
Hong D; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Qiu M; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 May 30; Vol. 345, pp. 128823. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Coffea/*chemistry
Diterpenes, Kaurane/*metabolism
Diterpenes, Kaurane/*pharmacology
Glycoside Hydrolase Inhibitors/*metabolism
Glycoside Hydrolase Inhibitors/*pharmacology
alpha-Glucosidases/*metabolism
Cooking ; Diterpenes, Kaurane/chemistry ; Glycoside Hydrolase Inhibitors/chemistry ; Magnetic Resonance Spectroscopy ; Protein Conformation ; alpha-Glucosidases/chemistry
Czasopismo naukowe

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