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Wyszukujesz frazę ""angiopoietin-2"" wg kryterium: Temat


Wyświetlanie 1-13 z 13
Tytuł:
Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases.
Autorzy:
Kahlert C; Department of General, Visceral and Transplantation Surgery, National Center for Tumor Diseases and Hamamatsu Tissue Imaging and Analysis (TIGA) Center, Institute for Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Pecqueux M; Department of General, Visceral and Thoracic Surgery, University of Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Halama N; Department of Medical Oncology, National Center for Tumor Diseases and Hamamatsu Tissue Imaging and Analysis (TIGA) Center, Institute for Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.
Dienemann H; Department of Thoracic Surgery, Thoraxklinik am Universitätsklinikum Heidelberg, Amalienstrasse 5, 69126 Heidelberg, Germany.
Muley T; Department of Thoracic Surgery, Thoraxklinik am Universitätsklinikum Heidelberg, Amalienstrasse 5, 69126 Heidelberg, Germany.
Pfannschmidt J; Department of Thoracic Surgery, Thoraxklinik am Universitätsklinikum Heidelberg, Amalienstrasse 5, 69126 Heidelberg, Germany.
Lasitschka F; Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany.
Klupp F; Department of General, Visceral and Transplantation Surgery, National Center for Tumor Diseases and Hamamatsu Tissue Imaging and Analysis (TIGA) Center, Institute for Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Schmidt T; Department of General, Visceral and Transplantation Surgery, National Center for Tumor Diseases and Hamamatsu Tissue Imaging and Analysis (TIGA) Center, Institute for Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Rahbari N; Department of General, Visceral and Transplantation Surgery, National Center for Tumor Diseases and Hamamatsu Tissue Imaging and Analysis (TIGA) Center, Institute for Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Reissfelder C; Department of General, Visceral and Thoracic Surgery, University of Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Kunz C; Division of Biostatistics, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Benner A; Division of Biostatistics, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Falk C; Medizinische Hochschule Hannover, Institut für Immunologie, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Weitz J; Department of General, Visceral and Thoracic Surgery, University of Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Koch M; Department of General, Visceral and Thoracic Surgery, University of Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
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Źródło:
British journal of cancer [Br J Cancer] 2014 Jan 21; Vol. 110 (2), pp. 441-9. Date of Electronic Publication: 2013 Nov 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiogenesis Inducing Agents/*metabolism
Biomarkers, Tumor/*biosynthesis
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*pathology
Stromal Cells/*pathology
Aged ; Angiopoietin-2/biosynthesis ; Angiopoietin-2/genetics ; Angiopoietin-2/metabolism ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Colorectal Neoplasms/genetics ; Cytokines/biosynthesis ; Cytokines/genetics ; Cytokines/metabolism ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Liver Neoplasms/secondary ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Lung Neoplasms/secondary ; Male ; Matrix Metalloproteinases/biosynthesis ; Matrix Metalloproteinases/genetics ; Matrix Metalloproteinases/metabolism ; Prognosis ; Stromal Cells/metabolism ; Transcriptome ; Vascular Endothelial Growth Factor A/biosynthesis ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł:
Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer.
Autorzy:
Lee SJ; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
Lee I; Biomedical Research Institute, Samsung Medical Center, Seoul 135-710, Korea.
Lee J; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
Park C; Biomedical Research Institute, Samsung Medical Center, Seoul 135-710, Korea.
Kang WK; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
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Źródło:
British journal of cancer [Br J Cancer] 2014 Jul 29; Vol. 111 (3), pp. 497-505. Date of Electronic Publication: 2014 Jun 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiogenesis Inhibitors/*pharmacology
Antibodies, Monoclonal, Humanized/*pharmacology
Colorectal Neoplasms/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology
Simvastatin/*pharmacology
Angiopoietin-2/metabolism ; Animals ; Bevacizumab ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Colorectal Neoplasms/blood supply ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Drug Synergism ; Endoplasmic Reticulum Chaperone BiP ; HSP90 Heat-Shock Proteins/metabolism ; Heat-Shock Proteins/metabolism ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/physiology ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/metabolism ; Peritoneal Neoplasms/drug therapy ; Peritoneal Neoplasms/metabolism ; Peritoneal Neoplasms/secondary ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Pro-angiogenic cytokines for prediction of outcomes in patients with advanced hepatocellular carcinoma.
Autorzy:
Miyahara K; Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama-city, Okayama 700-8558, Japan.
Nouso K
Morimoto Y
Takeuchi Y
Hagihara H
Kuwaki K
Onishi H
Ikeda F
Miyake Y
Nakamura S
Shiraha H
Takaki A
Honda M
Kaneko S
Sato T
Sato S
Obi S
Iwadou S
Kobayashi Y
Takaguchi K
Kariyama K
Takuma Y
Takabatake H
Yamamoto K
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Corporate Authors:
Okayama Liver Cancer Group
Źródło:
British journal of cancer [Br J Cancer] 2013 Oct 15; Vol. 109 (8), pp. 2072-8. Date of Electronic Publication: 2013 Sep 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular/*blood
Cytokines/*blood
Liver Neoplasms/*blood
Adult ; Aged ; Aged, 80 and over ; Angiopoietin-2/blood ; Antineoplastic Agents/therapeutic use ; Carcinoma, Hepatocellular/blood supply ; Carcinoma, Hepatocellular/drug therapy ; Cohort Studies ; Female ; Humans ; Liver Neoplasms/blood supply ; Liver Neoplasms/drug therapy ; Male ; Middle Aged ; Neovascularization, Pathologic/blood ; Niacinamide/analogs & derivatives ; Niacinamide/therapeutic use ; Phenylurea Compounds/therapeutic use ; Retrospective Studies ; Sorafenib
Czasopismo naukowe
Tytuł:
High bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes.
Autorzy:
Cheng CL; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, No. 7, Chung-Shan South Road, Taipei 10002, Taiwan.
Hou HA
Jhuang JY
Lin CW
Chen CY
Tang JL
Chou WC
Tseng MH
Yao M
Huang SY
Ko BS
Hsu SC
Wu SJ
Tsay W
Chen YC
Tien HF
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Źródło:
British journal of cancer [Br J Cancer] 2011 Sep 27; Vol. 105 (7), pp. 975-82. Date of Electronic Publication: 2011 Aug 30.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiopoietin-1/*metabolism
Bone Marrow/*metabolism
Myelodysplastic Syndromes/*metabolism
Myelodysplastic Syndromes/*mortality
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Angiopoietin-1/genetics ; Angiopoietin-2/genetics ; Angiopoietin-2/metabolism ; Case-Control Studies ; Cohort Studies ; Female ; Humans ; Immunoenzyme Techniques ; Male ; Middle Aged ; Myelodysplastic Syndromes/genetics ; Prognosis ; RNA, Messenger/genetics ; Receptor, TIE-2/genetics ; Receptor, TIE-2/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Survival Rate ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor C/genetics ; Vascular Endothelial Growth Factor C/metabolism ; Young Adult
Czasopismo naukowe
Tytuł:
Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer.
Autorzy:
Volkova E; Angiogenesis and Cancer Research Group, Department of Pathology, University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand.
Willis JA
Wells JE
Robinson BA
Dachs GU
Currie MJ
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Źródło:
British journal of cancer [Br J Cancer] 2011 Jan 04; Vol. 104 (1), pp. 51-9. Date of Electronic Publication: 2010 Nov 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Adenocarcinoma/*mortality
Angiopoietin-2/*blood
Biomarkers/*metabolism
C-Reactive Protein/*metabolism
Colorectal Neoplasms/*mortality
Obesity/*blood
Adenocarcinoma/blood ; Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; C-Peptide/blood ; Colorectal Neoplasms/blood ; Colorectal Neoplasms/pathology ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Insulin/blood ; Insulin-Like Growth Factor I/metabolism ; Male ; Middle Aged ; Prospective Studies ; Survival Rate ; Treatment Outcome ; Vascular Endothelial Growth Factor A/blood
Czasopismo naukowe
Tytuł:
Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy.
Autorzy:
Goede V; Department of Internal Medicine I, Center of Integrated Oncology Cologne-Bonn, University Hospital Cologne, Kerpener Straße 62, Cologne 50924, Germany.
Coutelle O
Neuneier J
Reinacher-Schick A
Schnell R
Koslowsky TC
Weihrauch MR
Cremer B
Kashkar H
Odenthal M
Augustin HG
Schmiegel W
Hallek M
Hacker UT
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Źródło:
British journal of cancer [Br J Cancer] 2010 Oct 26; Vol. 103 (9), pp. 1407-14. Date of Electronic Publication: 2010 Oct 05.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiopoietin-2/*blood
Antibodies, Monoclonal/*administration & dosage
Colorectal Neoplasms/*drug therapy
Aged ; Aged, 80 and over ; Animals ; Antibodies, Monoclonal, Humanized ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Bevacizumab ; Biomarkers, Tumor/blood ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/pathology ; Female ; Humans ; Male ; Mice ; Mice, Nude ; Middle Aged ; Prognosis ; Treatment Outcome ; Vascular Endothelial Growth Factor A/administration & dosage ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia.
Autorzy:
Lee CY; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No.1 Chang-Te Street, Taipei 10048, Taiwan.
Tien HF
Hu CY
Chou WC
Lin LI
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Źródło:
British journal of cancer [Br J Cancer] 2007 Oct 08; Vol. 97 (7), pp. 877-82. Date of Electronic Publication: 2007 Sep 11.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiogenesis Inducing Agents/*metabolism
Biomarkers, Tumor/*metabolism
Leukemia, Myeloid/*metabolism
Acute Disease ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Angiopoietin-1/metabolism ; Angiopoietin-2/metabolism ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Case-Control Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Leukemia, Myeloid/classification ; Leukemia, Myeloid/pathology ; Male ; Middle Aged ; Neovascularization, Pathologic ; Prognosis ; Receptor, TIE-2/metabolism ; Sensitivity and Specificity ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor C/metabolism ; Vascular Endothelial Growth Factor D/metabolism
Czasopismo naukowe
Tytuł:
Expression of the VEGF and angiopoietin genes in endometrial atypical hyperplasia and endometrial cancer.
Autorzy:
Holland CM; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB1 1QP, UK. />Day K
Evans A
Smith SK
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Źródło:
British journal of cancer [Br J Cancer] 2003 Sep 01; Vol. 89 (5), pp. 891-8.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiogenesis Inducing Agents/*biosynthesis
Endometrial Hyperplasia/*genetics
Endometrial Neoplasms/*genetics
Endothelial Growth Factors/*biosynthesis
Intercellular Signaling Peptides and Proteins/*biosynthesis
Lymphokines/*biosynthesis
Membrane Glycoproteins/*biosynthesis
Adult ; Aged ; Aged, 80 and over ; Angiogenesis Inducing Agents/genetics ; Angiopoietin-1 ; Angiopoietin-2 ; Antigens, CD/biosynthesis ; Antigens, CD/genetics ; Antigens, Differentiation, Myelomonocytic/biosynthesis ; Antigens, Differentiation, Myelomonocytic/genetics ; Endometrial Hyperplasia/metabolism ; Endometrial Neoplasms/metabolism ; Endothelial Growth Factors/genetics ; Epithelium/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Intercellular Signaling Peptides and Proteins/genetics ; Keratins/biosynthesis ; Keratins/genetics ; Lymphokines/genetics ; Membrane Glycoproteins/genetics ; Middle Aged ; RNA, Messenger/analysis ; Reverse Transcriptase Polymerase Chain Reaction ; Transcription, Genetic ; Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors
Czasopismo naukowe
    Wyświetlanie 1-13 z 13

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