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Tytuł:
Mutations accumulated in the Spike of SARS-CoV-2 Omicron allow for more efficient counteraction of the restriction factor BST2/Tetherin.
Autorzy:
Shi Y; Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.
Simpson S; Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.
Chen Y; Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.
Aull H; Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.
Benjamin J; Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.
Serra-Moreno R; Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Jan 08; Vol. 20 (1), pp. e1011912. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Bone Marrow Stromal Antigen 2*
COVID-19*/genetics
Humans ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/metabolism ; Mutation ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists.
Autorzy:
Hagelauer E; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, 72076 Tübingen, Germany.
Lotke R; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, 72076 Tübingen, Germany.
Kmiec D; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Hu D; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, 72076 Tübingen, Germany.
Hohner M; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, 72076 Tübingen, Germany.
Stopper S; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, 72076 Tübingen, Germany.
Nchioua R; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Kirchhoff F; Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Sauter D; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, 72076 Tübingen, Germany.
Schindler M; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, 72076 Tübingen, Germany.
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Źródło:
Viruses [Viruses] 2023 Nov 30; Vol. 15 (12). Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Marrow Stromal Antigen 2*
COVID-19*/metabolism
COVID-19*/virology
Severe acute respiratory syndrome-related coronavirus*
Humans ; Caco-2 Cells ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/metabolism ; HEK293 Cells ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Identification of Two Isoforms of Canine Tetherin in Domestic Dogs and Characterization of Their Antiviral Activity against Canine Influenza Virus.
Autorzy:
Xu L; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Ou J; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Hu X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Zheng Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Ye S; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Zhong L; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Lai Z; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Cai S; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Lu G; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
Li S; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China.; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, China.
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Źródło:
Viruses [Viruses] 2023 Jan 30; Vol. 15 (2). Date of Electronic Publication: 2023 Jan 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/immunology
Antiviral Agents*/therapeutic use
Bone Marrow Stromal Antigen 2*/immunology
Bone Marrow Stromal Antigen 2*/therapeutic use
Influenza A Virus, H3N2 Subtype*/immunology
Dog Diseases*/prevention & control
Orthomyxoviridae Infections*/prevention & control
Orthomyxoviridae Infections*/veterinary
Animals ; Dogs ; Amino Acids ; Glycosylphosphatidylinositols ; Protein Isoforms/genetics
Czasopismo naukowe
Tytuł:
BST2, a Novel Inhibitory Receptor, Is Involved in NK Cell Cytotoxicity through Its Cytoplasmic Tail Domain.
Autorzy:
Oh J; College of Life Science and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.
Yi E; College of Life Science and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.
Jeong SK; College of Life Science and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.
Park S; College of Life Science and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.
Park SH; College of Life Science and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 27; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 27.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Marrow Stromal Antigen 2*/genetics
Bone Marrow Stromal Antigen 2*/immunology
Cytotoxicity, Immunologic*/genetics
Cytotoxicity, Immunologic*/immunology
Killer Cells, Natural*/immunology
Animals ; Antibodies, Monoclonal/immunology ; Antigens, CD/genetics ; Antigens, CD/immunology ; Carrier Proteins/immunology ; Galectins/immunology ; Ligands ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/immunology ; Mice ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł:
Human BST2 inhibits rabies virus release independently of cysteine-linked dimerization and asparagine-linked glycosylation.
Autorzy:
Tanwattana N; Interdisciplinary Program in Genetic Engineering and Bioinformatics, Graduate School, Kasetsart University, Bangkok, Thailand.; Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, Thailand.
Wanasen N; Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, Thailand.
Jantraphakorn Y; Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, Thailand.
Srisutthisamphan K; Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, Thailand.
Chailungkarn T; Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, Thailand.
Boonrungsiman S; National Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), KlongLuang, Pathum Thani, Thailand.
Lumlertdacha B; Queen Saovabha Memorial Institute, Thai Red Cross Society, WHO Collaborating Center for Research and Training Prophylaxis on Rabies, Pathumwan, Bangkok, Thailand.
Lekchareonsuk P; Interdisciplinary Program in Genetic Engineering and Bioinformatics, Graduate School, Kasetsart University, Bangkok, Thailand.; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.; Center for Advance Studies in Agriculture and Food, KU Institute Studies, Kasetsart University, Bangkok, Thailand.
Kaewborisuth C; Interdisciplinary Program in Genetic Engineering and Bioinformatics, Graduate School, Kasetsart University, Bangkok, Thailand.; Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, Thailand.
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Źródło:
PloS one [PLoS One] 2023 Nov 03; Vol. 18 (11), pp. e0292833. Date of Electronic Publication: 2023 Nov 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Rabies virus*/physiology
Rabies*/prevention & control
Humans ; Glycosylation ; Asparagine/metabolism ; Cysteine/metabolism ; Dimerization ; Virus Release ; Bone Marrow Stromal Antigen 2/genetics ; Antigens, CD/metabolism ; GPI-Linked Proteins/metabolism
Czasopismo naukowe
Tytuł:
Tetherin downmodulation by SIVmac Nef lost with the H196Q escape variant is restored by an upstream variant.
Autorzy:
Schouest B; Division of Microbiology, Tulane National Primate Research Center, Covington, LA, United States of America.
Leslie GJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Hoxie JA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
Maness NJ; Division of Microbiology, Tulane National Primate Research Center, Covington, LA, United States of America.; Department of Microbiology and Immunology, School of Medicine, Tulane University Health Sciences Center, New Orleans, LA, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Aug 07; Vol. 15 (8), pp. e0225420. Date of Electronic Publication: 2020 Aug 07 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Bone Marrow Stromal Antigen 2/*metabolism
Simian Immunodeficiency Virus/*genetics
Viral Regulatory and Accessory Proteins/*genetics
Animals ; Antigens, CD/metabolism ; Bone Marrow Stromal Antigen 2/genetics ; CD4-Positive T-Lymphocytes/metabolism ; GPI-Linked Proteins/metabolism ; Gene Products, nef/metabolism ; Macaca mulatta/metabolism ; Simian Acquired Immunodeficiency Syndrome/virology ; Simian Immunodeficiency Virus/metabolism ; Simian Immunodeficiency Virus/physiology ; Viral Regulatory and Accessory Proteins/metabolism
Czasopismo naukowe
Tytuł:
Strain-Specific Antagonism of the Human H1N1 Influenza A Virus against Equine Tetherin.
Autorzy:
Wang M; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China. .
Zhang Z; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China. .
Wang X; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China. .
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Źródło:
Viruses [Viruses] 2018 May 16; Vol. 10 (5). Date of Electronic Publication: 2018 May 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Host-Pathogen Interactions*
Bone Marrow Stromal Antigen 2/*metabolism
Hemagglutinin Glycoproteins, Influenza Virus/*metabolism
Influenza A Virus, H1N1 Subtype/*metabolism
Neuraminidase/*metabolism
Animals ; Bone Marrow Stromal Antigen 2/chemistry ; Bone Marrow Stromal Antigen 2/genetics ; Dogs ; Glycosylphosphatidylinositols/physiology ; HEK293 Cells ; Hemagglutinin Glycoproteins, Influenza Virus/chemistry ; Hemagglutinin Glycoproteins, Influenza Virus/genetics ; Horses ; Humans ; Influenza A Virus, H1N1 Subtype/genetics ; Influenza A Virus, H3N8 Subtype/genetics ; Influenza A Virus, H3N8 Subtype/physiology ; Madin Darby Canine Kidney Cells ; Models, Molecular ; Mutation ; Neuraminidase/genetics ; Structure-Activity Relationship ; Virus Release
Czasopismo naukowe
Tytuł:
Novel Compound Inhibitors of HIV-1 NL4-3 Vpu.
Autorzy:
Robinson CA; Department of Molecular Microbiology and Immunology, University of Missouri, School of Medicine and the Christopher S. Bond Life Sciences Center, Columbia, MO 65211, USA.
Lyddon TD; Department of Molecular Microbiology and Immunology, University of Missouri, School of Medicine and the Christopher S. Bond Life Sciences Center, Columbia, MO 65211, USA.
Gil HM; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA.
Evans DT; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA.
Kuzmichev YV; Infectious Disease Research, Drug Development Division, Southern Research, Frederick, MD 21701, USA.
Richard J; Centre de Recherche du CHUM, Montréal, QC HX2 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC HX2 0A9, Canada.
Finzi A; Centre de Recherche du CHUM, Montréal, QC HX2 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC HX2 0A9, Canada.
Welbourn S; Department of Molecular Microbiology and Immunology, University of Missouri, School of Medicine and the Christopher S. Bond Life Sciences Center, Columbia, MO 65211, USA.
Rasmussen L; High-Throughput Screening Center, Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA.
Nebane NM; High-Throughput Screening Center, Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA.
Gupta VV; Department of Chemistry, Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA.
Ananthan S; Department of Chemistry, Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA.
Cai Z; Infectious Disease Research, Drug Development Division, Southern Research, Frederick, MD 21701, USA.
Wonderlich ER; Infectious Disease Research, Drug Development Division, Southern Research, Frederick, MD 21701, USA.
Augelli-Szafran CE; Department of Chemistry, Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA.
Bostwick R; High-Throughput Screening Center, Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA.
Ptak RG; Infectious Disease Research, Drug Development Division, Southern Research, Frederick, MD 21701, USA.
Schader SM; Infectious Disease Research, Drug Development Division, Southern Research, Frederick, MD 21701, USA.
Johnson MC; Department of Molecular Microbiology and Immunology, University of Missouri, School of Medicine and the Christopher S. Bond Life Sciences Center, Columbia, MO 65211, USA.
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Źródło:
Viruses [Viruses] 2022 Apr 15; Vol. 14 (4). Date of Electronic Publication: 2022 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-HIV Agents*/chemistry
HIV-1*/metabolism
Human Immunodeficiency Virus Proteins*/antagonists & inhibitors
Human Immunodeficiency Virus Proteins*/metabolism
Viral Regulatory and Accessory Proteins*/antagonists & inhibitors
Viral Regulatory and Accessory Proteins*/metabolism
Viroporin Proteins*/antagonists & inhibitors
Bone Marrow Stromal Antigen 2/metabolism ; GPI-Linked Proteins/metabolism ; Leukemia Virus, Gibbon Ape/metabolism ; Small Molecule Libraries
Czasopismo naukowe
Tytuł:
Dual Role of HIV-1 Envelope Signal Peptide in Immune Evasion.
Autorzy:
Upadhyay C; Division of Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA.
Rao PG; Division of Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA.
Feyznezhad R; Division of Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA.
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Źródło:
Viruses [Viruses] 2022 Apr 13; Vol. 14 (4). Date of Electronic Publication: 2022 Apr 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
HIV-1*/physiology
Bone Marrow Stromal Antigen 2/genetics ; GPI-Linked Proteins/genetics ; Genes, env ; Human Immunodeficiency Virus Proteins/genetics ; Human Immunodeficiency Virus Proteins/metabolism ; Immune Evasion ; Protein Sorting Signals/genetics ; Viral Regulatory and Accessory Proteins/genetics ; Viral Regulatory and Accessory Proteins/metabolism
Czasopismo naukowe
Tytuł:
Canine Influenza Virus is Mildly Restricted by Canine Tetherin Protein.
Autorzy:
Zheng Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Hao X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Zheng Q; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. qingxu_.; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. qingxu_.; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. qingxu_.
Lin X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Zhang X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Zeng W; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Ding S; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .
Zhou P; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
Li S; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. .; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China. .; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou 510642, China. .
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Źródło:
Viruses [Viruses] 2018 Oct 16; Vol. 10 (10). Date of Electronic Publication: 2018 Oct 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Marrow Stromal Antigen 2/*immunology
Dog Diseases/*immunology
Orthomyxoviridae/*physiology
Orthomyxoviridae Infections/*veterinary
Animals ; Bone Marrow Stromal Antigen 2/genetics ; Dog Diseases/genetics ; Dog Diseases/virology ; Dogs ; Interferon-alpha/genetics ; Interferon-alpha/immunology ; Orthomyxoviridae/genetics ; Orthomyxoviridae/immunology ; Orthomyxoviridae Infections/genetics ; Orthomyxoviridae Infections/immunology ; Orthomyxoviridae Infections/virology ; Virus Replication
Czasopismo naukowe
Tytuł:
Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients.
Autorzy:
Mlimi H; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, 4013, South Africa.
Naidoo KK; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, 4013, South Africa.
Mabuka J; Department of Global Health, University of Washington, Seattle, USA.
Ndung'u T; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, 4013, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Africa Health Research Institute (AHRI), Durban, KwaZulu-Natal, South Africa.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA, 02139, USA.; Division of Infection and Immunity, University College London, London, UK.
Madlala P; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, 4013, South Africa. .; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. .
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Źródło:
Retrovirology [Retrovirology] 2022 Jan 26; Vol. 19 (1), pp. 3. Date of Electronic Publication: 2022 Jan 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV Infections*/genetics
HIV-1*/genetics
Antigens, CD/*genetics
Antibody-Dependent Cell Cytotoxicity ; Bone Marrow Stromal Antigen 2 ; CD4-Positive T-Lymphocytes ; GPI-Linked Proteins/genetics ; HIV Envelope Protein gp120 ; Humans ; Immunoglobulin G ; Leukocytes, Mononuclear ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
High-Mannose But Not Complex-Type Glycosylation of Tetherin Is Required for Restriction of HIV-1 Release.
Autorzy:
Waheed AA; Virus-Cell Interaction Section, HIV Dynamics and Replication Program, National Cancer Institute, Bldg. 535, Room 108B, 1050 Boyles St., Frederick, MD 21702-1201, USA. .
Gitzen A; Virus-Cell Interaction Section, HIV Dynamics and Replication Program, National Cancer Institute, Bldg. 535, Room 108B, 1050 Boyles St., Frederick, MD 21702-1201, USA. .
Swiderski M; Virus-Cell Interaction Section, HIV Dynamics and Replication Program, National Cancer Institute, Bldg. 535, Room 108B, 1050 Boyles St., Frederick, MD 21702-1201, USA. .
Freed EO; Virus-Cell Interaction Section, HIV Dynamics and Replication Program, National Cancer Institute, Bldg. 535, Room 108B, 1050 Boyles St., Frederick, MD 21702-1201, USA. .
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Źródło:
Viruses [Viruses] 2018 Jan 05; Vol. 10 (1). Date of Electronic Publication: 2018 Jan 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Virus Release*
Bone Marrow Stromal Antigen 2/*metabolism
HIV Infections/*metabolism
HIV Infections/*virology
HIV-1/*physiology
Mannose/*metabolism
Bone Marrow Stromal Antigen 2/genetics ; Cell Line ; Cell Membrane/metabolism ; Gene Expression ; Glycosylation ; HIV Infections/genetics ; Host-Pathogen Interactions/genetics ; Humans ; Tunicamycin/pharmacology
Czasopismo naukowe
Tytuł:
The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells.
Autorzy:
Brinkmann C; Infection Biology Unit, German Primate Center, Kellnerweg 4, Göttingen, Germany.
Hoffmann M; Infection Biology Unit, German Primate Center, Kellnerweg 4, Göttingen, Germany.
Lübke A; Infection Biology Unit, German Primate Center, Kellnerweg 4, Göttingen, Germany.
Nehlmeier I; Infection Biology Unit, German Primate Center, Kellnerweg 4, Göttingen, Germany.
Krämer-Kühl A; Infection Biology Unit, German Primate Center, Kellnerweg 4, Göttingen, Germany.
Winkler M; Infection Biology Unit, German Primate Center, Kellnerweg 4, Göttingen, Germany.
Pöhlmann S; Infection Biology Unit, German Primate Center, Kellnerweg 4, Göttingen, Germany.
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Źródło:
PloS one [PLoS One] 2017 Dec 07; Vol. 12 (12), pp. e0189073. Date of Electronic Publication: 2017 Dec 07 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Bone Marrow Stromal Antigen 2/*metabolism
Vesiculovirus/*metabolism
Viral Proteins/*physiology
Virion/*physiology
Animals ; Bone Marrow Stromal Antigen 2/immunology ; Cell Line ; GTP-Binding Proteins/immunology ; Humans ; Swine
Czasopismo naukowe
Tytuł:
Parkinson's Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread.
Autorzy:
Ding Y; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Li Y; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Chhetri G; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Peng X; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Wu J; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Wang Z; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhao B; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhao W; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Li X; School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
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Źródło:
Cells [Cells] 2021 Mar 28; Vol. 10 (4). Date of Electronic Publication: 2021 Mar 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Marrow Stromal Antigen 2/*metabolism
Parkinson Disease/*metabolism
Parkinson Disease/*virology
Simplexvirus/*metabolism
Vesicular Transport Proteins/*metabolism
COVID-19/virology ; Cell Line, Tumor ; Endosomes/metabolism ; Humans ; Mutation ; Parkinson Disease/genetics ; Protein Transport/genetics ; SARS-CoV-2/growth & development ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity ; Simplexvirus/pathogenicity ; Transfection ; Vesicular Transport Proteins/genetics ; Virus Replication/genetics
Czasopismo naukowe
Tytuł:
The N-glycosylation of Equine Tetherin Affects Antiviral Activity by Regulating Its Subcellular Localization.
Autorzy:
Bai B; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150069, China.
Wang XF; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150069, China.; Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhang M; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150069, China.
Na L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150069, China.
Zhang X; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150069, China.
Zhang H; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150069, China.
Yang Z; Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Wang X; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150069, China.
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Źródło:
Viruses [Viruses] 2020 Feb 16; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Marrow Stromal Antigen 2/*genetics
Bone Marrow Stromal Antigen 2/*metabolism
Intracellular Space/*metabolism
Animals ; Endocytosis ; Glycosylation ; HEK293 Cells ; Horses ; Humans ; Mutation ; Protein Transport ; Virus Release
Czasopismo naukowe
Tytuł:
Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques.
Autorzy:
Tavakoli-Tameh A; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Janaka SK; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Zarbock K; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
O'Connor S; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Crosno K; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Capuano S 3rd; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Uno H; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.
Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Evans DT; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2020 Apr 17; Vol. 16 (4), pp. e1008487. Date of Electronic Publication: 2020 Apr 17 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Bone Marrow Stromal Antigen 2/*metabolism
Simian Acquired Immunodeficiency Syndrome/*virology
Simian Immunodeficiency Virus/*physiology
Viral Regulatory and Accessory Proteins/*genetics
Viral Regulatory and Accessory Proteins/*metabolism
Virus Replication/*physiology
Amino Acid Sequence ; Animals ; Antigens, CD/metabolism ; CD4-Positive T-Lymphocytes/virology ; Gene Products, nef ; Macaca mulatta ; Membrane Proteins/metabolism ; RNA, Viral/metabolism ; Simian Immunodeficiency Virus/genetics ; Simian Immunodeficiency Virus/metabolism ; Viral Load ; Viral Regulatory and Accessory Proteins/antagonists & inhibitors
Czasopismo naukowe
Tytuł:
Rapamycin Re-Directs Lysosome Network, Stimulates ER-Remodeling, Involving Membrane CD317 and Affecting Exocytosis, in Campylobacter Jejuni -Lysate-Infected U937 Cells.
Autorzy:
Canonico B; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Cesarini E; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Montanari M; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Di Sario G; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Campana R; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Galluzzi L; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Sola F; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Gundogdu O; Department of Pathogen Molecular Biology, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
Luchetti F; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Diotallevi A; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Baffone W; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Giordano A; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Temple University, Philadelphia, PA 19122, USA.; Department of Medical Botechnologies, University of Siena, 53100 Siena, Italy.
Papa S; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Mar 23; Vol. 21 (6). Date of Electronic Publication: 2020 Mar 23.
Typ publikacji:
Journal Article
MeSH Terms:
Exocytosis*/drug effects
Bone Marrow Stromal Antigen 2/*metabolism
Campylobacter jejuni/*physiology
Cell Membrane/*metabolism
Endoplasmic Reticulum/*metabolism
Lysosomes/*metabolism
Biomarkers ; Cell Death/drug effects ; Cell Proliferation ; Cells, Cultured ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum Stress ; Humans ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Prohibitins ; Signal Transduction/drug effects ; Sirolimus/pharmacology ; U937 Cells/metabolism ; U937 Cells/microbiology
Czasopismo naukowe
Tytuł:
Single Viruses on the Fluorescence Microscope: Imaging Molecular Mobility, Interactions and Structure Sheds New Light on Viral Replication.
Autorzy:
Parveen N; Laboratory for Photochemistry and Spectroscopy, Molecular Imaging and Photonics Division, Chemistry Department, KU Leuven, B-3001 Leuven, Belgium. .
Borrenberghs D; Laboratory for Photochemistry and Spectroscopy, Molecular Imaging and Photonics Division, Chemistry Department, KU Leuven, B-3001 Leuven, Belgium. .
Rocha S; Laboratory for Photochemistry and Spectroscopy, Molecular Imaging and Photonics Division, Chemistry Department, KU Leuven, B-3001 Leuven, Belgium. .
Hendrix J; Laboratory for Photochemistry and Spectroscopy, Molecular Imaging and Photonics Division, Chemistry Department, KU Leuven, B-3001 Leuven, Belgium. .; Dynamic Bioimaging Lab, Advanced Optical Microscopy Centre and Biomedical Research Institute (BIOMED), Hasselt University, B-3590 Diepenbeek, Belgium. .
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Źródło:
Viruses [Viruses] 2018 May 10; Vol. 10 (5). Date of Electronic Publication: 2018 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Virus Assembly*
Virus Replication*
HIV-1/*physiology
Microscopy, Fluorescence/*instrumentation
Bone Marrow Stromal Antigen 2/chemistry ; Fluorescence Resonance Energy Transfer ; HIV Integrase/chemistry ; Humans ; Microscopy, Confocal/instrumentation ; Protein Structure, Quaternary ; Simian virus 40
Czasopismo naukowe

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